Details for: DIS3
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.37
Marker Score: 2,016 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.23
Marker Score: 1,290 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.14
Marker Score: 69,887 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.13
Marker Score: 10,769 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 1.1
Marker Score: 2,713 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.1
Marker Score: 9,470 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.09
Marker Score: 1,684 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.07
Marker Score: 21,379 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.07
Marker Score: 1,138 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.04
Marker Score: 38,520 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.02
Marker Score: 3,949 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.02
Marker Score: 680 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.02
Marker Score: 9,556 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1
Marker Score: 683 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1
Marker Score: 2,282 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,651 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,874 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.99
Marker Score: 673 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.99
Marker Score: 228 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.99
Marker Score: 4,117 - Cell Name: basal cell (CL0000646)
Fold Change: 0.98
Marker Score: 1,267 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,383 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.95
Marker Score: 571 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 0.95
Marker Score: 933 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,386 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.93
Marker Score: 35,430 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.93
Marker Score: 3,426 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 472 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 431 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.91
Marker Score: 1,812 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9
Marker Score: 3,492 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,682 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.89
Marker Score: 312 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.89
Marker Score: 9,213 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.89
Marker Score: 213 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,290 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.87
Marker Score: 4,961 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 0.87
Marker Score: 307 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.86
Marker Score: 12,924 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.86
Marker Score: 489 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.85
Marker Score: 246 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.85
Marker Score: 3,523 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 0.85
Marker Score: 791 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.83
Marker Score: 205 - Cell Name: neuron (CL0000540)
Fold Change: 0.82
Marker Score: 3,338 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.81
Marker Score: 349 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.8
Marker Score: 6,155 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8
Marker Score: 320 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.8
Marker Score: 1,409 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.79
Marker Score: 8,927 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.79
Marker Score: 619 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.79
Marker Score: 1,141 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.79
Marker Score: 535 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.78
Marker Score: 903 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.78
Marker Score: 235 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.78
Marker Score: 187 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.78
Marker Score: 496 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.78
Marker Score: 532 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,258 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 592 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.77
Marker Score: 26,082 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 0.76
Marker Score: 377 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.76
Marker Score: 355 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.76
Marker Score: 839 - Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
Fold Change: 0.76
Marker Score: 171 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.76
Marker Score: 799 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.75
Marker Score: 26,135 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.75
Marker Score: 691 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.75
Marker Score: 305 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.75
Marker Score: 258 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.75
Marker Score: 362 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.74
Marker Score: 215 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.74
Marker Score: 746 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.74
Marker Score: 161 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.73
Marker Score: 252 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.73
Marker Score: 212 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.72
Marker Score: 908 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.72
Marker Score: 567 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.72
Marker Score: 6,214 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.72
Marker Score: 169 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.72
Marker Score: 1,109 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.71
Marker Score: 370 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.71
Marker Score: 457 - Cell Name: neural cell (CL0002319)
Fold Change: 0.71
Marker Score: 344 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.71
Marker Score: 425 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.71
Marker Score: 355 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.71
Marker Score: 469 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.71
Marker Score: 4,613 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.71
Marker Score: 286 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.71
Marker Score: 7,147 - Cell Name: type I enteroendocrine cell (CL0002277)
Fold Change: 0.7
Marker Score: 174 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 0.7
Marker Score: 751 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.69
Marker Score: 155 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.69
Marker Score: 170 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.69
Marker Score: 317 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.69
Marker Score: 750 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.69
Marker Score: 504 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 176 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.69
Marker Score: 193
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2773712452
Symbol: RRP44_HUMAN
Name: Exosome complex exonuclease RRP44
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9562621
Title: Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3.
PubMed ID: 9562621
PubMed ID: 11935316
Title: A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes.
PubMed ID: 11935316
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19056938
Title: RNA exosome depletion reveals transcription upstream of active human promoters.
PubMed ID: 19056938
PubMed ID: 12429849
Title: Functional proteomic analysis of human nucleolus.
PubMed ID: 12429849
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20531386
Title: The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.
PubMed ID: 20531386
PubMed ID: 20531389
Title: Dis3-like 1: a novel exoribonuclease associated with the human exosome.
PubMed ID: 20531389
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25220460
Title: The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.
PubMed ID: 25220460
PubMed ID: 29906447
Title: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
PubMed ID: 29906447
Sequence Information:
- Length: 958
- Mass: 109003
- Checksum: 92336BA0D06247FE
- Sequence:
MLKSKTFLKK TRAGGVMKIV REHYLRDDIG CGAPGCAACG GAHEGPALEP QPQDPASSVC PQPHYLLPDT NVLLHQIDVL EDPAIRNVIV LQTVLQEVRN RSAPVYKRIR DVTNNQEKHF YTFTNEHHRE TYVEQEQGEN ANDRNDRAIR VAAKWYNEHL KKMSADNQLQ VIFITNDRRN KEKAIEEGIP AFTCEEYVKS LTANPELIDR LACLSEEGNE IESGKIIFSE HLPLSKLQQG IKSGTYLQGT FRASRENYLE ATVWIHGDNE ENKEIILQGL KHLNRAVHED IVAVELLPKS QWVAPSSVVL HDEGQNEEDV EKEEETERML KTAVSEKMLK PTGRVVGIIK RNWRPYCGML SKSDIKESRR HLFTPADKRI PRIRIETRQA STLEGRRIIV AIDGWPRNSR YPNGHFVRNL GDVGEKETET EVLLLEHDVP HQPFSQAVLS FLPKMPWSIT EKDMKNREDL RHLCICSVDP PGCTDIDDAL HCRELENGNL EVGVHIADVS HFIRPGNALD QESARRGTTV YLCEKRIDMV PELLSSNLCS LKCDVDRLAF SCIWEMNHNA EILKTKFTKS VINSKASLTY AEAQLRIDSA NMNDDITTSL RGLNKLAKIL KKRRIEKGAL TLSSPEVRFH MDSETHDPID LQTKELRETN SMVEEFMLLA NISVAKKIHE EFSEHALLRK HPAPPPSNYE ILVKAARSRN LEIKTDTAKS LAESLDQAES PTFPYLNTLL RILATRCMMQ AVYFCSGMDN DFHHYGLASP IYTHFTSPIR RYADVIVHRL LAVAIGADCT YPELTDKHKL ADICKNLNFR HKMAQYAQRA SVAFHTQLFF KSKGIVSEEA YILFVRKNAI VVLIPKYGLE GTVFFEEKDK PNPQLIYDDE IPSLKIEDTV FHVFDKVKVK IMLDSSNLQH QKIRMSLVEP QIPGISIPTD TSNMDLNGPK KKKMKLGK
Genular Protein ID: 577656020
Symbol: G3V1J5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 796
- Mass: 90584
- Checksum: 4DFB954BBFFD6EE1
- Sequence:
MSADNQLQVI FITNDRRNKE KAIEEGIPAF TCEEYVKSLT ANPELIDRLA CLSEEGNEIE SGKIIFSEHL PLSKLQQGIK SGTYLQGTFR ASRENYLEAT VWIHGDNEEN KEIILQGLKH LNRAVHEDIV AVELLPKSQW VAPSSVVLHD EGQNEEDVEK EEETERMLKT AVSEKMLKPT GRVVGIIKRN WRPYCGMLSK SDIKESRRHL FTPADKRIPR IRIETRQAST LEGRRIIVAI DGWPRNSRYP NGHFVRNLGD VGEKETETEV LLLEHDVPHQ PFSQAVLSFL PKMPWSITEK DMKNREDLRH LCICSVDPPG CTDIDDALHC RELENGNLEV GVHIADVSHF IRPGNALDQE SARRGTTVYL CEKRIDMVPE LLSSNLCSLK CDVDRLAFSC IWEMNHNAEI LKTKFTKSVI NSKASLTYAE AQLRIDSANM NDDITTSLRG LNKLAKILKK RRIEKGALTL SSPEVRFHMD SETHDPIDLQ TKELRETNSM VEEFMLLANI SVAKKIHEEF SEHALLRKHP APPPSNYEIL VKAARSRNLE IKTDTAKSLA ESLDQAESPT FPYLNTLLRI LATRCMMQAV YFCSGMDNDF HHYGLASPIY THFTSPIRRY ADVIVHRLLA VAIGADCTYP ELTDKHKLAD ICKNLNFRHK MAQYAQRASV AFHTQLFFKS KGIVSEEAYI LFVRKNAIVV LIPKYGLEGT VFFEEKDKPN PQLIYDDEIP SLKIEDTVFH VFDKVKVKIM LDSSNLQHQK IRMSLVEPQI PGISIPTDTS NMDLNGPKKK KMKLGK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.