Details for: ARHGEF15
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 3.17
Marker Score: 1,667 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.36
Marker Score: 20,682 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1,172 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.38
Marker Score: 873 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.34
Marker Score: 1,339 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.34
Marker Score: 1,264 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.18
Marker Score: 489 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4,818 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.03
Marker Score: 698 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,831 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,056 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 511 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 465 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,409 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 0.96
Marker Score: 2,429 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.95
Marker Score: 1,374 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.94
Marker Score: 376 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,352 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.93
Marker Score: 429 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 0.92
Marker Score: 828 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,741 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 328 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,292 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.86
Marker Score: 1,724 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.81
Marker Score: 194 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 710 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,262 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 399 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.77
Marker Score: 508 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 583 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 0.73
Marker Score: 1,058 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.73
Marker Score: 465 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 179 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 0.66
Marker Score: 154 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.66
Marker Score: 590 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.66
Marker Score: 392 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.61
Marker Score: 190 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.59
Marker Score: 471 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.57
Marker Score: 238 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 0.57
Marker Score: 490 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.56
Marker Score: 149 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.56
Marker Score: 952 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.55
Marker Score: 594 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.55
Marker Score: 8,615 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.55
Marker Score: 174 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 0.55
Marker Score: 128 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 0.54
Marker Score: 586 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 0.54
Marker Score: 546 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.49
Marker Score: 477 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.49
Marker Score: 933 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 0.48
Marker Score: 133 - Cell Name: glomerular endothelial cell (CL0002188)
Fold Change: 0.45
Marker Score: 115 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.44
Marker Score: 893 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.43
Marker Score: 166 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 0.42
Marker Score: 90 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.41
Marker Score: 2,741 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.38
Marker Score: 159 - Cell Name: erythroid lineage cell (CL0000764)
Fold Change: 0.38
Marker Score: 189 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.37
Marker Score: 374 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.33
Marker Score: 185 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.32
Marker Score: 70 - Cell Name: vasa recta ascending limb cell (CL1001131)
Fold Change: 0.29
Marker Score: 78 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 0.27
Marker Score: 66 - Cell Name: Unknown (CL0000003)
Fold Change: 0.27
Marker Score: 822 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.24
Marker Score: 147 - Cell Name: endocardial cell (CL0002350)
Fold Change: 0.24
Marker Score: 138 - Cell Name: glomerular capillary endothelial cell (CL1001005)
Fold Change: 0.24
Marker Score: 67 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.23
Marker Score: 65 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.22
Marker Score: 74 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 0.21
Marker Score: 129 - Cell Name: vasa recta descending limb cell (CL1001285)
Fold Change: 0.19
Marker Score: 52 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.18
Marker Score: 86 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.17
Marker Score: 42 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.16
Marker Score: 59 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.15
Marker Score: 67 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.14
Marker Score: 62 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.13
Marker Score: 34 - Cell Name: erythrocyte (CL0000232)
Fold Change: 0.13
Marker Score: 70 - Cell Name: mast cell (CL0000097)
Fold Change: 0.13
Marker Score: 73 - Cell Name: podocyte (CL0000653)
Fold Change: 0.12
Marker Score: 46 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.11
Marker Score: 34 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.11
Marker Score: 34 - Cell Name: monocyte (CL0000576)
Fold Change: 0.09
Marker Score: 119 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.09
Marker Score: 43 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.08
Marker Score: 798 - Cell Name: B cell (CL0000236)
Fold Change: 0.08
Marker Score: 79 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.08
Marker Score: 40 - Cell Name: leukocyte (CL0000738)
Fold Change: 0.08
Marker Score: 47 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.08
Marker Score: 78 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.08
Marker Score: 98 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.08
Marker Score: 18 - Cell Name: macrophage (CL0000235)
Fold Change: 0.08
Marker Score: 86 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.08
Marker Score: 19 - Cell Name: PP cell (CL0000696)
Fold Change: 0.08
Marker Score: 17 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.07
Marker Score: 17 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 0.07
Marker Score: 18 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.07
Marker Score: 723 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.07
Marker Score: 19 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.07
Marker Score: 18
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 89462269
Symbol: ARHGF_HUMAN
Name: Rho guanine nucleotide exchange factor 15
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12775584
Title: EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells.
PubMed ID: 12775584
PubMed ID: 23647072
Title: Exome sequencing reveals new causal mutations in children with epileptic encephalopathies.
PubMed ID: 23647072
DOI: 10.1111/epi.12201
Sequence Information:
- Length: 841
- Mass: 91940
- Checksum: 40D430ACF777002F
- Sequence:
MSAQSLPAAT PPTQKPPRII RPRPPSRSRA AQSPGPPHNG SSPQELPRNS NDAPTPMCTP IFWEPPAASL KPPALLPPSA SRASLDSQTS PDSPSSTPTP SPVSRRSASP EPAPRSPVPP PKPSGSPCTP LLPMAGVLAQ NGSASAPGTV RRLAGRFEGG AEGRAQDADA PEPGLQARAD VNGEREAPLT GSGSQENGAP DAGLACPPCC PCVCHTTRPG LELRWVPVGG YEEVPRVPRR ASPLRTSRSR PHPPSIGHPA VVLTSYRSTA ERKLLPLLKP PKPTRVRQDA TIFGDPPQPD LDLLSEDGIQ TGDSPDEAPQ NTPPATVEGR EEEGLEVLKE QNWELPLQDE PLYQTYRAAV LSEELWGVGE DGSPSPANAG DAPTFPRPPG PRNTLWQELP AVQASGLLDT LSPQERRMQE SLFEVVTSEA SYLRSLRLLT DTFVLSQALR DTLTPRDHHT LFSNVQRVQG VSERFLATLL SRVRSSPHIS DLCDVVHAHA VGPFSVYVDY VRNQQYQEET YSRLMDTNVR FSAELRRLQS LPKCERLPLP SFLLLPFQRI TRLRMLLQNI LRQTEEGSSR QENAQKALGA VSKIIERCSA EVGRMKQTEE LIRLTQRLRF HKVKALPLVS WSRRLEFQGE LTELGCRRGG VLFASRPRFT PLCLLLFSDL LLITQPKSGQ RLQVLDYAHR SLVQAQQVPD PSGPPTFRLS LLSNHQGRPT HRLLQASSLS DMQRWLGAFP TPGPLPCSPD TIYEDCDCSQ ELCSESSAPA KTEGRSLESR AAPKHLHKTP EGWLKGLPGA FPAQLVCEVT GEHERRRHLR QNQRLLEAVG SSSGTPNAPP P
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.