Details for: ARSG
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.96
Marker Score: 821 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.89
Marker Score: 1,079 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.79
Marker Score: 3,646 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.71
Marker Score: 4,276 - Cell Name: interneuron (CL0000099)
Fold Change: 1.65
Marker Score: 755 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.56
Marker Score: 492 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.55
Marker Score: 493 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.55
Marker Score: 453 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.55
Marker Score: 57,100 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.52
Marker Score: 416 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.44
Marker Score: 867 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.32
Marker Score: 20,671 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.31
Marker Score: 4,668 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.31
Marker Score: 1,627 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.3
Marker Score: 29,154 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.27
Marker Score: 1,966 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.23
Marker Score: 595 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.23
Marker Score: 75,355 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.22
Marker Score: 1,345 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.2
Marker Score: 4,986 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.14
Marker Score: 367 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.11
Marker Score: 37,901 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.02
Marker Score: 9,722 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.01
Marker Score: 316 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1
Marker Score: 19,837 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,402 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.98
Marker Score: 5,881 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 0.97
Marker Score: 242 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.97
Marker Score: 9,116 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.96
Marker Score: 242 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,408 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.94
Marker Score: 35,803 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 485 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.94
Marker Score: 3,924 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.94
Marker Score: 13,990 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.93
Marker Score: 2,201 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 439 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.92
Marker Score: 549 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.92
Marker Score: 3,550 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 0.92
Marker Score: 382 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,722 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.9
Marker Score: 7,722 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5,052 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.88
Marker Score: 354 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.88
Marker Score: 595 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.85
Marker Score: 407 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.85
Marker Score: 353 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.84
Marker Score: 965 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.84
Marker Score: 1,183 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.79
Marker Score: 3,400 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.77
Marker Score: 3,552 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.76
Marker Score: 1,231 - Cell Name: neuron (CL0000540)
Fold Change: 0.74
Marker Score: 3,009 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.74
Marker Score: 3,098 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.73
Marker Score: 554 - Cell Name: fat cell (CL0000136)
Fold Change: 0.71
Marker Score: 394 - Cell Name: brush cell (CL0002204)
Fold Change: 0.7
Marker Score: 640 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.67
Marker Score: 389 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: 0.66
Marker Score: 235 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.65
Marker Score: 412 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.63
Marker Score: 11,199 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.63
Marker Score: 2,426 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.61
Marker Score: 1,350 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.61
Marker Score: 650 - Cell Name: germ cell (CL0000586)
Fold Change: 0.61
Marker Score: 1,069 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.61
Marker Score: 247 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.61
Marker Score: 176 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.6
Marker Score: 267 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.59
Marker Score: 313 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.58
Marker Score: 4,438 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.57
Marker Score: 955 - Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
Fold Change: 0.57
Marker Score: 501 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.55
Marker Score: 139 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.54
Marker Score: 317 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.54
Marker Score: 1,537 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.54
Marker Score: 610 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.53
Marker Score: 426 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.52
Marker Score: 165 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.52
Marker Score: 515 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.51
Marker Score: 252 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.51
Marker Score: 390 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.5
Marker Score: 331 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.5
Marker Score: 130 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.49
Marker Score: 1,216 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.49
Marker Score: 178 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.49
Marker Score: 4,134 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.48
Marker Score: 304 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.46
Marker Score: 452 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.46
Marker Score: 161 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.46
Marker Score: 15,565 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.45
Marker Score: 875 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.45
Marker Score: 294 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.44
Marker Score: 165 - Cell Name: tracheobronchial goblet cell (CL0019003)
Fold Change: 0.44
Marker Score: 121 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.44
Marker Score: 153 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.43
Marker Score: 110 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 0.43
Marker Score: 91
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2084845442
Symbol: ARSG_HUMAN
Name: Arylsulfatase G
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12461688
Title: Molecular and biochemical characterisation of a novel sulphatase gene: arylsulfatase G (ARSG).
PubMed ID: 12461688
PubMed ID: 18283100
Title: Arylsulfatase G, a novel lysosomal sulfatase.
PubMed ID: 18283100
PubMed ID: 22689975
Title: Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice.
PubMed ID: 22689975
PubMed ID: 25135642
Title: Molecular characterization of arylsulfatase G: expression, processing, glycosylation, transport, and activity.
PubMed ID: 25135642
PubMed ID: 29300381
Title: A homozygous founder missense variant in arylsulfatase G abolishes its enzymatic activity causing atypical Usher syndrome in humans.
PubMed ID: 29300381
DOI: 10.1038/gim.2017.227
PubMed ID: 25825126
Title: Accumulation of rare variants in the arylsulfatase G (ARSG) gene in task-specific dystonia.
PubMed ID: 25825126
Sequence Information:
- Length: 525
- Mass: 57061
- Checksum: ADAB673A02B25754
- Sequence:
MGWLFLKVLL AGVSFSGFLY PLVDFCISGK TRGQKPNFVI ILADDMGWGD LGANWAETKD TANLDKMASE GMRFVDFHAA ASTCSPSRAS LLTGRLGLRN GVTRNFAVTS VGGLPLNETT LAEVLQQAGY VTGIIGKWHL GHHGSYHPNF RGFDYYFGIP YSHDMGCTDT PGYNHPPCPA CPQGDGPSRN LQRDCYTDVA LPLYENLNIV EQPVNLSSLA QKYAEKATQF IQRASTSGRP FLLYVALAHM HVPLPVTQLP AAPRGRSLYG AGLWEMDSLV GQIKDKVDHT VKENTFLWFT GDNGPWAQKC ELAGSVGPFT GFWQTRQGGS PAKQTTWEGG HRVPALAYWP GRVPVNVTST ALLSVLDIFP TVVALAQASL PQGRRFDGVD VSEVLFGRSQ PGHRVLFHPN SGAAGEFGAL QTVRLERYKA FYITGGARAC DGSTGPELQH KFPLIFNLED DTAEAVPLER GGAEYQAVLP EVRKVLADVL QDIANDNISS ADYTQDPSVT PCCNPYQIAC RCQAA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.