Details for: MAPRE1

Gene ID: 22919

Symbol: MAPRE1

Ensembl ID: ENSG00000101367

Description: microtubule associated protein RP/EB family member 1

Associated with

Other Information

Genular Protein ID: 3382404052

Symbol: MARE1_HUMAN

Name: Microtubule-associated protein RP/EB family member 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7606712

Title: APC binds to the novel protein EB1.

PubMed ID: 7606712

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9724749

Title: The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules.

PubMed ID: 9724749

DOI: 10.1073/pnas.95.18.10596

PubMed ID: 10226031

Title: The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.

PubMed ID: 10226031

DOI: 10.1016/s0960-9822(99)80190-0

PubMed ID: 10188731

Title: EB/RP gene family encodes tubulin binding proteins.

PubMed ID: 10188731

DOI: 10.1002/(sici)1097-0215(19990412)81:2<275::aid-ijc18>3.0.co;2-z

PubMed ID: 10644998

Title: EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue.

PubMed ID: 10644998

DOI: 10.1038/sj.onc.1203308

PubMed ID: 11943150

Title: Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle.

PubMed ID: 11943150

DOI: 10.1016/s0014-5793(02)02363-3

PubMed ID: 12388762

Title: Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.

PubMed ID: 12388762

DOI: 10.1091/mbc.e02-01-0061

PubMed ID: 14514668

Title: Characterization of functional domains of human EB1 family proteins.

PubMed ID: 14514668

DOI: 10.1074/jbc.m306194200

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15631994

Title: CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.

PubMed ID: 15631994

DOI: 10.1083/jcb.200405094

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17293347

Title: Regulated binding of adenomatous polyposis coli protein to actin.

PubMed ID: 17293347

DOI: 10.1074/jbc.m610615200

PubMed ID: 17563362

Title: Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition.

PubMed ID: 17563362

DOI: 10.1073/pnas.0703876104

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19543227

Title: TIP150 interacts with and targets MCAK at the microtubule plus ends.

PubMed ID: 19543227

DOI: 10.1038/embor.2009.94

PubMed ID: 19255245

Title: Mammalian end binding proteins control persistent microtubule growth.

PubMed ID: 19255245

DOI: 10.1083/jcb.200807179

PubMed ID: 19553473

Title: Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics.

PubMed ID: 19553473

DOI: 10.1091/mbc.e09-01-0009

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21303978

Title: Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the alpha-tubulin tyrosination cycle.

PubMed ID: 21303978

DOI: 10.1158/0008-5472.can-10-2294

PubMed ID: 21820309

Title: A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases.

PubMed ID: 21820309

DOI: 10.1016/j.cub.2011.07.017

PubMed ID: 21646404

Title: SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase.

PubMed ID: 21646404

DOI: 10.1083/jcb.201012179

PubMed ID: 23035123

Title: Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.

PubMed ID: 23035123

DOI: 10.1074/jbc.m112.406652

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23001180

Title: EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.

PubMed ID: 23001180

DOI: 10.1073/pnas.1202639109

PubMed ID: 23509069

Title: MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.

PubMed ID: 23509069

DOI: 10.1083/jcb.201207050

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23874158

Title: Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor.

PubMed ID: 23874158

DOI: 10.1371/journal.pbio.1001611

PubMed ID: 24706950

Title: GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins.

PubMed ID: 24706950

DOI: 10.1242/jcs.140558

PubMed ID: 25217626

Title: A newly identified myomegalin isoform functions in Golgi microtubule organization and ER-Golgi transport.

PubMed ID: 25217626

DOI: 10.1242/jcs.155408

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26485573

Title: Cep169, a novel microtubule plus-end-tracking centrosomal protein, binds to CDK5RAP2 and regulates microtubule stability.

PubMed ID: 26485573

DOI: 10.1371/journal.pone.0140968

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28726242

Title: Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk.

PubMed ID: 28726242

DOI: 10.1002/1873-3468.12758

PubMed ID: 28814570

Title: EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.

PubMed ID: 28814570

DOI: 10.1083/jcb.201701024

PubMed ID: 29162697

Title: EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

PubMed ID: 29162697

DOI: 10.1073/pnas.1705682114

PubMed ID: 34608293

Title: Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis.

PubMed ID: 34608293

DOI: 10.1038/s41589-021-00875-7

PubMed ID: 15616574

Title: Structural insights into the EB1-APC interaction.

PubMed ID: 15616574

DOI: 10.1038/sj.emboj.7600529

PubMed ID: 12857735

Title: Crystal structure of the amino-terminal microtubule-binding domain of end-binding protein 1 (EB1).

PubMed ID: 12857735

DOI: 10.1074/jbc.m305773200

PubMed ID: 16109370

Title: Structural basis for the activation of microtubule assembly by the EB1 and p150Glued complex.

PubMed ID: 16109370

DOI: 10.1016/j.molcel.2005.06.034

PubMed ID: 16949363

Title: Key interaction modes of dynamic +TIP networks.

PubMed ID: 16949363

DOI: 10.1016/j.molcel.2006.07.013

PubMed ID: 17889670

Title: Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.

PubMed ID: 17889670

DOI: 10.1016/j.molcel.2007.07.023

PubMed ID: 19632184

Title: An EB1-binding motif acts as a microtubule tip localization signal.

PubMed ID: 19632184

DOI: 10.1016/j.cell.2009.04.065

Sequence Information:

  • Length: 268
  • Mass: 29999
  • Checksum: 08C8999F45A145ED
  • Sequence:
  • MAVNVYSTSV TSDNLSRHDM LAWINESLQL NLTKIEQLCS GAAYCQFMDM LFPGSIALKK 
    VKFQAKLEHE YIQNFKILQA GFKRMGVDKI IPVDKLVKGK FQDNFEFVQW FKKFFDANYD 
    GKDYDPVAAR QGQETAVAPS LVAPALNKPK KPLTSSSAAP QRPISTQRTA AAPKAGPGVV 
    RKNPGVGNGD DEAAELMQQV NVLKLTVEDL EKERDFYFGK LRNIELICQE NEGENDPVLQ 
    RIVDILYATD EGFVIPDEGG PQEEQEEY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.