Details for: ELL2

Gene ID: 22936

Symbol: ELL2

Ensembl ID: ENSG00000118985

Description: elongation factor for RNA polymerase II 2

Associated with

Other Information

Genular Protein ID: 3149365234

Symbol: ELL2_HUMAN

Name: RNA polymerase II elongation factor ELL2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9108030

Title: ELL2, a new member of an ELL family of RNA polymerase II elongation factors.

PubMed ID: 9108030

DOI: 10.1073/pnas.94.8.3639

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11418481

Title: EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.

PubMed ID: 11418481

DOI: 10.1182/blood.v98.1.201

PubMed ID: 12446457

Title: ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.

PubMed ID: 12446457

DOI: 10.1182/blood-2002-06-1664

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20471948

Title: HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.

PubMed ID: 20471948

DOI: 10.1016/j.molcel.2010.04.013

PubMed ID: 20159561

Title: AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.

PubMed ID: 20159561

DOI: 10.1016/j.molcel.2010.01.026

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22195968

Title: The little elongation complex regulates small nuclear RNA transcription.

PubMed ID: 22195968

DOI: 10.1016/j.molcel.2011.12.008

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22483617

Title: The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription.

PubMed ID: 22483617

DOI: 10.1016/j.molcel.2012.03.007

PubMed ID: 22895430

Title: The super elongation complex (SEC) family in transcriptional control.

PubMed ID: 22895430

DOI: 10.1038/nrm3417

PubMed ID: 23251033

Title: HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.

PubMed ID: 23251033

DOI: 10.1073/pnas.1216971110

Sequence Information:

  • Length: 640
  • Mass: 72324
  • Checksum: 96D6228AF868E6C9
  • Sequence:
  • MAAGGTGGLR EEQRYGLSCG RLGQDNITVL HVKLTETAIR ALETYQSHKN LIPFRPSIQF 
    QGLHGLVKIP KNDPLNEVHN FNFYLSNVGK DNPQGSFDCI QQTFSSSGAS QLNCLGFIQD 
    KITVCATNDS YQMTRERMTQ AEEESRNRST KVIKPGGPYV GKRVQIRKAP QAVSDTVPER 
    KRSTPMNPAN TIRKTHSSST ISQRPYRDRV IHLLALKAYK KPELLARLQK DGVNQKDKNS 
    LGAILQQVAN LNSKDLSYTL KDYVFKELQR DWPGYSEIDR RSLESVLSRK LNPSQNAAGT 
    SRSESPVCSS RDAVSSPQKR LLDSEFIDPL MNKKARISHL TNRVPPTLNG HLNPTSEKSA 
    AGLPLPPAAA AIPTPPPLPS TYLPISHPPQ IVNSNSNSPS TPEGRGTQDL PVDSFSQNDS 
    IYEDQQDKYT SRTSLETLPP GSVLLKCPKP MEENHSMSHK KSKKKSKKHK EKDQIKKHDI 
    ETIEEKEEDL KREEEIAKLN NSSPNSSGGV KEDCTASMEP SAIELPDYLI KYIAIVSYEQ 
    RQNYKDDFNA EYDEYRALHA RMETVARRFI KLDAQRKRLS PGSKEYQNVH EEVLQEYQKI 
    KQSSPNYHEE KYRCEYLHNK LAHIKRLIGE FDQQQAESWS

Genular Protein ID: 3054236197

Symbol: Q7Z656_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 309
  • Mass: 35797
  • Checksum: 012CA5B9EBEBD3AA
  • Sequence:
  • RGWRVGSNRS LDLHKEPWTW GLPRPRRLSR KRVAGPSHLP SPTPPPLPST YLPISHPPQI 
    VNSNSNSPST PEGRGTQDLP VDSFSQNDSI YEDQQDKYTS RTSLETLPPG SVLLKCPKPM 
    EENHSMSHKK SKKKSKKHKE KDQIKKHDIE AIEEKEEDLK REEEIAKLNN SSPNSSGGVK 
    EDCTASMEPS AIELPDYSIK YIAIVSYEQR QNYKDDFNAE YDEYRALHAR METVARRFIK 
    LDAQRKRLST GSKEYQNVHE EVLQEYQKIK QSSPNYHEEK YRCEYLHNKL AHIKRLIGEF 
    DQQQAESWS

Genular Protein ID: 1711392966

Symbol: Q59FW6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 519
  • Mass: 59004
  • Checksum: 6CCD0AFF04194A6F
  • Sequence:
  • ITVCATNDSY QMTRERMTQA EEESRNRSTK VIKPGGPYVG KRVQIRKAPQ AVSDTVPERK 
    RSTPMNPANT IRKTHSSSTI SQRPYRDRVI HLLALKAYKK PELLARLQKD GVNQKDKNSL 
    GAILQQVANL NSKDLSYTLK DYVFKELQRD WPGYSEIDRR SLESVLSRKL NPSQNAAGTS 
    RSESPVCSSR DAVSSPQKRL LDSEFIDPLM NKKARISHLT NRVPPTLNGH LNPTSEKSAA 
    GLPLPPAAAA IPTPPPLPST YLPISHPPQI VNSNSNSPST PEGRGTQDLP VDSFSQNDSI 
    YEDQQDKYTS RTSLETLPPG SVLLKCPKPM EENHSMSHKK SKKKSKKHKE KDQIKKHDIE 
    TIEEKEEDLK REEEIAKLNN SSPNSSGGVK EDCTASMEPS AIELPDYLIK YIAIVSYEQR 
    QNYKDDFNAE YDEYRALHAR METVARRFIK LDAQRKRLSP GSKEYQNVHE EVLQEYQKIK 
    QSSPNYHEEK YRCEYLHNKL AHIKRLIGEF DQQQAESWS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.