Details for: SCAP
Associated with
Other Information
Genular Protein ID: 2523116010
Symbol: SCAP_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10570913
Title: Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene.
PubMed ID: 10570913
PubMed ID: 8724849
Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 8724849
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16303743
Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
PubMed ID: 16303743
PubMed ID: 15133039
Title: Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor.
PubMed ID: 15133039
PubMed ID: 17428920
Title: Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig.
PubMed ID: 17428920
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 26160948
Title: Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels.
PubMed ID: 26160948
PubMed ID: 19706601
Title: The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage.
PubMed ID: 19706601
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28849786
Title: SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.
PubMed ID: 28849786
PubMed ID: 32111832
Title: Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
PubMed ID: 32111832
PubMed ID: 10570919
Title: A common Ile796Val polymorphism of the human SREBP cleavage-activating protein (SCAP) gene.
PubMed ID: 10570919
Sequence Information:
- Length: 1279
- Mass: 139729
- Checksum: 4CD73543B7D2ACB4
- Sequence:
MTLTERLREK ISRAFYNHGL LCASYPIPII LFTGFCILAC CYPLLKLPLP GTGPVEFTTP VKDYSPPPVD SDRKQGEPTE QPEWYVGAPV AYVQQIFVKS SVFPWHKNLL AVDVFRSPLS RAFQLVEEIR NHVLRDSSGI RSLEELCLQV TDLLPGLRKL RNLLPEHGCL LLSPGNFWQN DWERFHADPD IIGTIHQHEP KTLQTSATLK DLLFGVPGKY SGVSLYTRKR MVSYTITLVF QHYHAKFLGS LRARLMLLHP SPNCSLRAES LVHVHFKEEI GVAELIPLVT TYIILFAYIY FSTRKIDMVK SKWGLALAAV VTVLSSLLMS VGLCTLFGLT PTLNGGEIFP YLVVVIGLEN VLVLTKSVVS TPVDLEVKLR IAQGLSSESW SIMKNMATEL GIILIGYFTL VPAIQEFCLF AVVGLVSDFF LQMLFFTTVL SIDIRRMELA DLNKRLPPEA CLPSAKPVGQ PTRYERQLAV RPSTPHTITL QPSSFRNLRL PKRLRVVYFL ARTRLAQRLI MAGTVVWIGI LVYTDPAGLR NYLAAQVTEQ SPLGEGALAP MPVPSGMLPP SHPDPAFSIF PPDAPKLPEN QTSPGESPER GGPAEVVHDS PVPEVTWGPE DEELWRKLSF RHWPTLFSYY NITLAKRYIS LLPVIPVTLR LNPREALEGR HPQDGRSAWP PPGPIPAGHW EAGPKGPGGV QAHGDVTLYK VAALGLATGI VLVLLLLCLY RVLCPRNYGQ LGGGPGRRRR GELPCDDYGY APPETEIVPL VLRGHLMDIE CLASDGMLLV SCCLAGHVCV WDAQTGDCLT RIPRPGRQRR DSGVGSGLEA QESWERLSDG GKAGPEEPGD SPPLRHRPRG PPPPSLFGDQ PDLTCLIDTN FSAQPRSSQP TQPEPRHRAV CGRSRDSPGY DFSCLVQRVY QEEGLAAVCT PALRPPSPGP VLSQAPEDEG GSPEKGSPSL AWAPSAEGSI WSLELQGNLI VVGRSSGRLE VWDAIEGVLC CSSEEVSSGI TALVFLDKRI VAARLNGSLD FFSLETHTAL SPLQFRGTPG RGSSPASPVY SSSDTVACHL THTVPCAHQK PITALKAAAG RLVTGSQDHT LRVFRLEDSC CLFTLQGHSG AITTVYIDQT MVLASGGQDG AICLWDVLTG SRVSHVFAHR GDVTSLTCTT SCVISSGLDD LISIWDRSTG IKFYSIQQDL GCGASLGVIS DNLLVTGGQG CVSFWDLNYG DLLQTVYLGK NSEAQPARQI LVLDNAAIVC NFGSELSLVY VPSVLEKLD
Genular Protein ID: 1186514138
Symbol: B7Z6H0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1023
- Mass: 110602
- Checksum: D48EFB54D5BE919C
- Sequence:
MLLHPSPNCS LRAESLVHVH FKEEIGVAEL IPLVTTYIIL FAYIYFSTRK IDMVKSKWGL ALAAVVTVLS SLLMSVGLCT LFGLTPTLNG GEIFPYLVVV IGLENVLVLT KSVVSTPVDL EVKLRIAQGL SSESWSIMKN MATELGIILI GYFTLVPAIQ EFCLFAVVGL VSDFFLQMLF FTTVLSIDIR RMELADLNKR LPPEACLPSA KPVGQPTRYE RQLAVRPSTP HTITLQPSSF RNLRLPKRLR VVYFLARTRL AQRLIMAGTV VWIGILVYTD PAGLRNYLAA QVTEQSPLGE GALAPMPVPS GMLPPSHPDP AFSIFPPDAP KLPENQTSPG ESPERGGPAE VVHDSPVPEV TWGPEDEELW RKLSFRHWPT LFSYYNITLA KRYISLLPVI PVTLRLNPRE ALEGRHPQDG RSAWPPPGPI PAGHWEAGPK GPGGVQAHGD VTLYKVAALG LATGIVLVLL LLCLYRVLCP RNYEQLGGGP GRRRRGELPC DDYGYAPPET EIVPLVLRGH LMDIECLASD GMLLVSCCLA GHICVWDAQT GDCLTRIPRP GQRRDSGVGS GLEAQESWER LSDGGKAGPE EPGDSPPLRH RPRGPPPPSL FGDQPDLTCL IDTNFSAQPR SSQPTQPEPR HRAVCGRSQD SPGYDFSCLV QRVYQEEGLA AVCTPALRPP SPGPVLSQAP EDEGGSPEKG SPSLAWAPSA EGSIWSLELQ GNLIVVGRSS GRLEVWDAIE GVLCCSSEEV SSGITALVFL DKRIVAARLN GSLDFFSLET HTALSPLQFR GTPGRGSSPA SPVYSSSDTV ACHLTHTVPC AHQKPITALK AAAGRLVTGS QDHTLRVFRL EDSCCLFTLQ GHSGAITTVY IDQTMVLASG GQDGAICLWD VLTGSRVSHV FAHRGDVTSL TCTTSCVISS GLDDLISIWD RSTGIKFYSI QQDLGCGASL GVISDNLLVT GGQGCVSFWD LNYGDLLQTV YLGKNSEAQP ARQILVLDNA AIVCNFGSEL SLVYVPSVLE KLD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.