ABCF1 - ENSG00000204574

Details for: ABCF1

Gene ID: 23

Symbol: ABCF1

Ensembl ID: ENSG00000204574

Description: ATP binding cassette subfamily F member 1

Associated with

Abc-family proteins mediated transport (R-HSA-382556)
Transport of small molecules (R-HSA-382551)
Atp binding (GO:0005524)
Atp hydrolysis activity (GO:0016887)
Cytosol (GO:0005829)
Inflammatory response (GO:0006954)
Membrane (GO:0016020)
Nuclear envelope (GO:0005635)
Nucleoplasm (GO:0005654)
Protein binding (GO:0005515)
Rna binding (GO:0003723)
Translation (GO:0006412)
Translation factor activity, rna binding (GO:0008135)

Cells (max top 100)

Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 3.16
Marker Score: 2823.5
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.9
Marker Score: 64727
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.76
Marker Score: 2590
Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 1.67
Marker Score: 1419.5
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.64
Marker Score: 6447.5
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.6
Marker Score: 18026
Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.59
Marker Score: 5869.5
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.58
Marker Score: 3858.5
Cell Name: cell in vitro (CL0001034)
Fold Change: 1.57
Marker Score: 54370
Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 1.55
Marker Score: 1866
Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: 1.52
Marker Score: 921
Cell Name: male germ cell (CL0000015)
Fold Change: 1.5
Marker Score: 431
Cell Name: proerythroblast (CL0000547)
Fold Change: 1.49
Marker Score: 1009
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.49
Marker Score: 7303
Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.45
Marker Score: 968
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.45
Marker Score: 1523
Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.44
Marker Score: 1018
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.43
Marker Score: 3259
Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.4
Marker Score: 1760.5
Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.38
Marker Score: 940
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.35
Marker Score: 1406
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.35
Marker Score: 1439
Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 1.34
Marker Score: 899
Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 1.3
Marker Score: 819
Cell Name: plasmablast (CL0000980)
Fold Change: 1.29
Marker Score: 1715
Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.28
Marker Score: 853
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.28
Marker Score: 1356
Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.28
Marker Score: 553
Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 1.28
Marker Score: 632
Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.27
Marker Score: 11121
Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.27
Marker Score: 998
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.25
Marker Score: 371
Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 1.24
Marker Score: 364
Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 1.24
Marker Score: 1705
Cell Name: blood cell (CL0000081)
Fold Change: 1.24
Marker Score: 14410
Cell Name: classical monocyte (CL0000860)
Fold Change: 1.24
Marker Score: 5136.5
Cell Name: pro-T cell (CL0000827)
Fold Change: 1.22
Marker Score: 4997
Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.22
Marker Score: 2543
Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.21
Marker Score: 604
Cell Name: supporting cell (CL0000630)
Fold Change: 1.2
Marker Score: 2252
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.18
Marker Score: 282
Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.16
Marker Score: 562.5
Cell Name: oogonial cell (CL0000024)
Fold Change: 1.16
Marker Score: 1664
Cell Name: osteoclast (CL0000092)
Fold Change: 1.15
Marker Score: 575
Cell Name: primitive red blood cell (CL0002355)
Fold Change: 1.15
Marker Score: 862
Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.15
Marker Score: 463
Cell Name: enterocyte (CL0000584)
Fold Change: 1.14
Marker Score: 5493
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: 1.14
Marker Score: 638
Cell Name: radial glial cell (CL0000681)
Fold Change: 1.14
Marker Score: 421
Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.14
Marker Score: 1939
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.14
Marker Score: 1137
Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.14
Marker Score: 7251
Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.14
Marker Score: 1143
Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.13
Marker Score: 3180
Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.13
Marker Score: 2668
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.13
Marker Score: 4355
Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.12
Marker Score: 638
Cell Name: hepatocyte (CL0000182)
Fold Change: 1.11
Marker Score: 761
Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 1.11
Marker Score: 267
Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 1.1
Marker Score: 290
Cell Name: Leydig cell (CL0000178)
Fold Change: 1.1
Marker Score: 1185
Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 1.1
Marker Score: 339.5
Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.09
Marker Score: 1550
Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 1.09
Marker Score: 743
Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 1.08
Marker Score: 14423
Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.08
Marker Score: 2945.5
Cell Name: mature T cell (CL0002419)
Fold Change: 1.08
Marker Score: 10715
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.07
Marker Score: 1890
Cell Name: Unknown (CL0000548)
Fold Change: 1.06
Marker Score: 775
Cell Name: adventitial cell (CL0002503)
Fold Change: 1.06
Marker Score: 262.5
Cell Name: epithelial cell (CL0000066)
Fold Change: 1.06
Marker Score: 1686
Cell Name: pneumocyte (CL0000322)
Fold Change: 1.06
Marker Score: 1701.5
Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.05
Marker Score: 303
Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 1.05
Marker Score: 279
Cell Name: ependymal cell (CL0000065)
Fold Change: 1.05
Marker Score: 365
Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.04
Marker Score: 245
Cell Name: enteric neuron (CL0007011)
Fold Change: 1.04
Marker Score: 555
Cell Name: megakaryocyte (CL0000556)
Fold Change: 1.04
Marker Score: 591
Cell Name: kidney cell (CL1000497)
Fold Change: 1.04
Marker Score: 693
Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.04
Marker Score: 2073.5
Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.04
Marker Score: 227
Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 1.03
Marker Score: 505
Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.03
Marker Score: 2347
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.03
Marker Score: 1140
Cell Name: stem cell (CL0000034)
Fold Change: 1.03
Marker Score: 2451
Cell Name: B-1 B cell (CL0000819)
Fold Change: 1.03
Marker Score: 1793.5
Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 1.02
Marker Score: 526.5
Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.02
Marker Score: 596
Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 1.02
Marker Score: 5375
Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.02
Marker Score: 938
Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.02
Marker Score: 1567
Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.01
Marker Score: 1660.5
Cell Name: stromal cell (CL0000499)
Fold Change: 1.01
Marker Score: 1184
Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.01
Marker Score: 471
Cell Name: leukocyte (CL0000738)
Fold Change: 1.01
Marker Score: 578
Cell Name: mucus secreting cell (CL0000319)
Fold Change: 1.01
Marker Score: 256
Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 1
Marker Score: 340
Cell Name: keratocyte (CL0002363)
Fold Change: 1
Marker Score: 231
Cell Name: neural crest cell (CL0011012)
Fold Change: 1
Marker Score: 1071
Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1
Marker Score: 289

**Key characteristics:** * ABCF1 is a protein of approximately 130 kDa. * It is a transmembrane protein with a cytoplasmic domain and two transmembrane domains. * It is a chaperone protein that is involved in the folding and trafficking of other proteins. * ABCF1 is a highly conserved protein, with a similar sequence in mammals and humans. **Pathways and functions:** * ABCF1 is involved in the regulation of cellular energy production. * It is a key regulator of the expression of genes involved in fatty acid uptake, oxidation, and metabolism. * It also regulates the activity of mitochondrial enzymes. * ABCF1 is involved in the regulation of inflammation and cell growth. **Clinical significance:** * Mutations in ABCF1 have been linked to a number of human diseases, including breast cancer, ovarian cancer, and diabetes. * ABCF1 is a potential target for cancer therapy. * By targeting ABCF1, it may be possible to inhibit cancer growth and metastasis.

Database document:

Only first 5 entries are kept for 'singleCellExpressions', 'mRNAExpressions' and other large data arrays.