Details for: ABCF1

Gene ID: 23

Symbol: ABCF1

Ensembl ID: ENSG00000204574

Description: ATP binding cassette subfamily F member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 233.8870
    Cell Significance Index: -36.3800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 150.2503
    Cell Significance Index: -38.1100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 106.5401
    Cell Significance Index: -50.3000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 102.9397
    Cell Significance Index: -41.8200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 90.6713
    Cell Significance Index: -46.6400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 75.1540
    Cell Significance Index: -50.4300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 44.5041
    Cell Significance Index: -42.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 34.6890
    Cell Significance Index: -42.7700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.0072
    Cell Significance Index: -45.5600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.2290
    Cell Significance Index: -44.3100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.3111
    Cell Significance Index: -31.6700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.5368
    Cell Significance Index: -16.5000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 4.6838
    Cell Significance Index: 116.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.4656
    Cell Significance Index: 239.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.4424
    Cell Significance Index: 66.4800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.9899
    Cell Significance Index: 244.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.7953
    Cell Significance Index: 323.6400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.6935
    Cell Significance Index: 76.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3687
    Cell Significance Index: 222.6100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.2669
    Cell Significance Index: 65.8100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.2624
    Cell Significance Index: 11.6300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.2136
    Cell Significance Index: 34.7900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.2047
    Cell Significance Index: 34.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1803
    Cell Significance Index: 234.2300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.0492
    Cell Significance Index: 54.6500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0101
    Cell Significance Index: 551.6500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.9274
    Cell Significance Index: 11.0600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.8350
    Cell Significance Index: 52.6300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7806
    Cell Significance Index: 107.2000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.7621
    Cell Significance Index: 20.3500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7525
    Cell Significance Index: 332.7100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7512
    Cell Significance Index: 35.3100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7010
    Cell Significance Index: 49.5800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5904
    Cell Significance Index: 12.7900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5139
    Cell Significance Index: 23.9600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4930
    Cell Significance Index: 63.6900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.4692
    Cell Significance Index: 34.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3610
    Cell Significance Index: 72.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3146
    Cell Significance Index: 37.1000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3037
    Cell Significance Index: 108.9300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2896
    Cell Significance Index: 18.6900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2816
    Cell Significance Index: 36.1000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2174
    Cell Significance Index: 2.4700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2013
    Cell Significance Index: 181.8000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1806
    Cell Significance Index: 124.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1688
    Cell Significance Index: 32.1300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1644
    Cell Significance Index: 8.3100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1422
    Cell Significance Index: 14.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1251
    Cell Significance Index: 21.3700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1123
    Cell Significance Index: 2.3500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0161
    Cell Significance Index: 0.5600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0104
    Cell Significance Index: 0.2900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0086
    Cell Significance Index: 15.9300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0055
    Cell Significance Index: 8.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0031
    Cell Significance Index: 5.7900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0017
    Cell Significance Index: -1.3100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0027
    Cell Significance Index: -2.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0162
    Cell Significance Index: -21.9600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0213
    Cell Significance Index: -13.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0250
    Cell Significance Index: -18.5000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0313
    Cell Significance Index: -19.8600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0430
    Cell Significance Index: -1.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0522
    Cell Significance Index: -29.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0527
    Cell Significance Index: -2.9600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0536
    Cell Significance Index: -0.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0636
    Cell Significance Index: -28.8600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0689
    Cell Significance Index: -7.8900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0879
    Cell Significance Index: -8.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1155
    Cell Significance Index: -8.8700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1183
    Cell Significance Index: -1.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1287
    Cell Significance Index: -15.0000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1373
    Cell Significance Index: -28.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1419
    Cell Significance Index: -7.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1604
    Cell Significance Index: -46.1500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2003
    Cell Significance Index: -29.1200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2027
    Cell Significance Index: -3.4100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.2226
    Cell Significance Index: -2.4200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2697
    Cell Significance Index: -30.7900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3071
    Cell Significance Index: -4.1900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3471
    Cell Significance Index: -2.8300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3548
    Cell Significance Index: -9.3300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3797
    Cell Significance Index: -9.7000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3933
    Cell Significance Index: -11.5500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4163
    Cell Significance Index: -43.3500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4211
    Cell Significance Index: -9.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4390
    Cell Significance Index: -19.4200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4550
    Cell Significance Index: -8.8800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4653
    Cell Significance Index: -8.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4702
    Cell Significance Index: -37.2400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4843
    Cell Significance Index: -12.4500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5942
    Cell Significance Index: -22.5000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6389
    Cell Significance Index: -39.1700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.6422
    Cell Significance Index: -3.8800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.6447
    Cell Significance Index: -26.4200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6865
    Cell Significance Index: -14.6200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7037
    Cell Significance Index: -17.5900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7228
    Cell Significance Index: -23.1500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7459
    Cell Significance Index: -21.9700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.8008
    Cell Significance Index: -11.4000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.8747
    Cell Significance Index: -5.4400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ABCF1 is a member of the ATP-binding cassette (ABC) family of transporters, which are known for their ability to mediate the efflux of various compounds across cellular membranes. ABCF1 exhibits a unique ability to transport a wide range of molecules, including ions, metabolites, and even proteins. Its expression is widespread, with significant presence in various cell types, including extravillous trophoblasts, fibroblasts, and immune cells such as CD8-positive T cells. **Pathways and Functions:** ABCF1 plays a crucial role in several cellular signaling pathways, including: 1. **Abc-family proteins mediated transport**: ABCF1 contributes to the efflux of molecules across the plasma membrane, influencing cellular homeostasis and signaling. 2. **ATP hydrolysis activity**: ABCF1 utilizes ATP hydrolysis to drive the transport of molecules, highlighting its connection to energy metabolism. 3. **Inflammatory response**: ABCF1 has been implicated in the regulation of inflammatory responses, with potential implications for the management of inflammatory diseases. 4. **Translation and translation factor activity**: ABCF1 modulates protein synthesis and translation, affecting cellular growth and differentiation. **Clinical Significance:** The clinical relevance of ABCF1 lies in its potential role in various immune-related disorders. Some of the potential applications of ABCF1 include: 1. **Immunotherapy**: ABCF1 may serve as a target for immunotherapeutic interventions, particularly in the context of cancer and autoimmune diseases. 2. **Inflammatory disorders**: ABCF1's involvement in inflammatory responses suggests that it may be a valuable therapeutic target for the management of inflammatory conditions. 3. **Regulation of immune cell function**: ABCF1's role in modulating immune cell function highlights its potential as a regulator of immune responses, with implications for the treatment of immune-related diseases. In conclusion, ABCF1 is a multifaceted gene that plays a critical role in various cellular processes, including transport, signaling, and translation. Its clinical significance lies in its potential applications in immunotherapy, inflammatory disorder management, and regulation of immune cell function. Further research is necessary to fully elucidate the functional significance of ABCF1 and its potential therapeutic applications.

Genular Protein ID: 2322123127

Symbol: ABCF1_HUMAN

Name: ATP-binding cassette sub-family F member 1

UniProtKB Accession Codes:

Q8NE71 A2BF75 O14897 Q69YP6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CTD 1 ChEBI 2 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 16 Ensembl 14 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9790762

Title: ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes.

PubMed ID: 9790762

DOI: 10.1006/geno.1998.5480

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 17894550

Title: The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2.

PubMed ID: 17894550

DOI: 10.1042/bj20070811

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19570978

Title: ABC50 promotes translation initiation in mammalian cells.

PubMed ID: 19570978

DOI: 10.1074/jbc.m109.031625

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 845
  • Mass: 95926
  • Checksum: 5C5AA662DF4C99E4
  • Sequence:
    • MPKAPKQQPP EPEWIGDGES TSPSDKVVKK GKKDKKIKKT FFEELAVEDK QAGEEEKVLK 
EKEQQQQQQQ QQQKKKRDTR KGRRKKDVDD DGEEKELMER LKKLSVPTSD EEDEVPAPKP 
RGGKKTKGGN VFAALIQDQS EEEEEEEKHP PKPAKPEKNR INKAVSEEQQ PALKGKKGKE 
EKSKGKAKPQ NKFAALDNEE EDKEEEIIKE KEPPKQGKEK AKKAEQGSEE EGEGEEEEEE 
GGESKADDPY AHLSKKEKKK LKKQMEYERQ VASLKAANAA ENDFSVSQAE MSSRQAMLEN 
ASDIKLEKFS ISAHGKELFV NADLYIVAGR RYGLVGPNGK GKTTLLKHIA NRALSIPPNI 
DVLLCEQEVV ADETPAVQAV LRADTKRLKL LEEERRLQGQ LEQGDDTAAE RLEKVYEELR 
ATGAAAAEAK ARRILAGLGF DPEMQNRPTQ KFSGGWRMRV SLARALFMEP TLLMLDEPTN 
HLDLNAVIWL NNYLQGWRKT LLIVSHDQGF LDDVCTDIIH LDAQRLHYYR GNYMTFKKMY 
QQKQKELLKQ YEKQEKKLKE LKAGGKSTKQ AEKQTKEALT RKQQKCRRKN QDEESQEAPE 
LLKRPKEYTV RFTFPDPPPL SPPVLGLHGV TFGYQGQKPL FKNLDFGIDM DSRICIVGPN 
GVGKSTLLLL LTGKLTPTHG EMRKNHRLKI GFFNQQYAEQ LRMEETPTEY LQRGFNLPYQ 
DARKCLGRFG LESHAHTIQI CKLSGGQKAR VVFAELACRE PDVLILDEPT NNLDIESIDA 
LGEAINEYKG AVIVVSHDAR LITETNCQLW VVEEQSVSQI DGDFEDYKRE VLEALGEVMV 
SRPRE

Genular Protein ID: 2196753924

Symbol: Q2L6I2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2L6I2

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 ExpressionAtlas 1 GO 3 Gene3D 1 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16702430

Title: Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.

PubMed ID: 16702430

DOI: 10.1534/genetics.106.057034

Sequence Information:

  • Length: 807
  • Mass: 91680
  • Checksum: 1B6547EABEE7FC75
  • Sequence:
    • MPKAPKQQPP EPEWIGDGES TSPSDKVVKK GKKDKKIKKT FFEELAVEDK QAGEEEKVLK 
EKEQQQQQQQ QQQKKKRDTR KGRRKKDVDD DGEEKELMER LKKLSVPTSD EEDEVPAPKP 
RGGKKTKGGN VFAALIQDQS EEEEEEEKHP PKPAKPEKNR INKAVSEEQQ PALKGKKGKE 
EKSKGKAKPQ NKFAALDNEE EDKEEEIIKE KEPPKQGKEK AKKAEQMEYE RQVASLKAAN 
AAENDFSVSQ AEMSSRQAML ENASDIKLEK FSISAHGKEL FVNADLYIVA GRRYGLVGPN 
GKGKTTLLKH IANRALSIPP NIDVLLCEQE VVADETPAVQ AVLRADTKRL KLLEEERRLQ 
GQLEQGDDTA AERLEKVYEE LRATGAAAAE AKARRILAGL GFDPEMQNRP TQKFSGGWRM 
RVSLARALFM EPTLLMLDEP TNHLDLNAVI WLNNYLQGWR KTLLIVSHDQ GFLDDVCTDI 
IHLDAQRLHY YRGNYMTFKK MYQQKQKELL KQYEKQEKKL KELKAGGKST KQAEKQTKEA 
LTRKQQKCRR KNQDEESQEA PELLKRPKEY TVRFTFPDPP PLSPPVLGLH GVTFGYQGQK 
PLFKNLDFGI DMDSRICIVG PNGVGKSTLL LLLTGKLTPT HGEMRKNHRL KIGFFNQQYA 
EQLRMEETPT EYLQRGFNLP YQDARKCLGR FGLESHAHTI QICKLSGGQK ARVVFAELAC 
REPDVLILDE PTNNLDIESI DALGEAINEY KGAVIVVSHD ARLITETNCQ LWVVEEQSVS 
QIDGDFEDYK REVLEALGEV MVSRPRE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.