KLHDC10 | ENSG00000128607 | NCBI 23008

Details for: KLHDC10

Gene ID: 23008

Symbol: KLHDC10

Ensembl ID: ENSG00000128607

Description: kelch domain containing 10

Associated with

Cul2-ring ubiquitin ligase complex
(GO:0031462)
Cytoplasm
(GO:0005737)
Nucleoplasm
(GO:0005654)
Positive regulation of stress-activated mapk cascade
(GO:0032874)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)
Rescue of stalled ribosome
(GO:0072344)
Ubiquitin-dependent protein catabolic process via the c-end degron rule pathway
(GO:0140627)
Ubiquitin ligase-substrate adaptor activity
(GO:1990756)

Other Information

Proteins

KLD10_HUMAN

Genular Protein ID: 1086936511

Symbol: KLD10_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PID8 Q86Y99 Q92554

Database IDs:

Citations:

PubMed ID: 9039502

Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PubMed ID: 9039502

DOI: 10.1093/dnares/3.5.321

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14962666

Title: Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST-flanking region at human chromosome 7q32.

PubMed ID: 14962666

DOI: 10.1016/j.ygeno.2003.08.016

PubMed ID: 23102700

Title: The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5.

PubMed ID: 23102700

DOI: 10.1016/j.molcel.2012.09.018

PubMed ID: 29779948

Title: The eukaryotic proteome is shaped by E3 ubiquitin ligases targeting C-terminal degrons.

PubMed ID: 29779948

DOI: 10.1016/j.cell.2018.04.028

PubMed ID: 33909987

Title: Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing.

PubMed ID: 33909987

DOI: 10.1016/j.molcel.2021.03.004

Sequence Information:

Length: 442
Mass: 49098
Checksum: 8D8AF4A6302A7A86
Sequence:

MSAAQGWDRN RRRGGGAAGA GGGGSGAGGG SGGSGGRGTG QLNRFVQLSG RPHLPGKKKI 
RWDPVRRRFI QSCPIIRIPN RFLRGHRPPP ARSGHRCVAD NTNLYVFGGY NPDYDESGGP 
DNEDYPLFRE LWRYHFATGV WHQMGTDGYM PRELASMSLV LHGNNLLVFG GTGIPFGESN 
GNDVHVCNVK YKRWALLSCR GKKPSRIYGQ AMAIINGSLY VFGGTTGYIY STDLHKLDLN 
TREWTQLKPN NLSCDLPEER YRHEIAHDGQ RIYILGGGTS WTAYSLNKIH AYNLETNAWE 
EIATKPHEKI GFPAARRCHS CVQIKNDVFI CGGYNGEVIL GDIWKLNLQT FQWVKLPATM 
PEPVYFHCAA VTPAGCMYIH GGVVNIHENK RTGSLFKIWL VVPSLLELAW EKLLAAFPNL 
ANLSRTQLLH LGLTQGLIER LK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: KLHDC10

Associated with

Other Information

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. PubMed ID: 9039502

Human chromosome 7: DNA sequence and biology. PubMed ID: 12690205

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST-flanking region at human chromosome 7q32. PubMed ID: 14962666

The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5. PubMed ID: 23102700

The eukaryotic proteome is shaped by E3 ubiquitin ligases targeting C-terminal degrons. PubMed ID: 29779948

Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing. PubMed ID: 33909987