Details for: FAIM2

Gene ID: 23017

Symbol: FAIM2

Ensembl ID: ENSG00000135472

Description: Fas apoptotic inhibitory molecule 2

Associated with

Other Information

Genular Protein ID: 1485890307

Symbol: LFG2_HUMAN

Name: Protein lifeguard 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10535980

Title: LFG: an anti-apoptotic gene that provides protection from fas-mediated cell death.

PubMed ID: 10535980

DOI: 10.1073/pnas.96.22.12667

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16964429

Title: Sequence analysis shows that Lifeguard belongs to a new evolutionarily conserved cytoprotective family.

PubMed ID: 16964429

PubMed ID: 17635665

Title: Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment.

PubMed ID: 17635665

DOI: 10.1111/j.1471-4159.2007.04767.x

PubMed ID: 19784873

Title: LFG: a candidate apoptosis regulatory gene family.

PubMed ID: 19784873

DOI: 10.1007/s10495-009-0402-2

PubMed ID: 20336373

Title: Transactivation of lifeguard (LFG) by Akt-/LEF-1 pathway in MCF-7 and MDA-MB 231 human breast cancer cells.

PubMed ID: 20336373

DOI: 10.1007/s10495-010-0493-9

PubMed ID: 20336406

Title: The anti-apoptotic protein lifeguard is expressed in breast cancer cells and tissues.

PubMed ID: 20336406

DOI: 10.2478/s11658-010-0009-1

Sequence Information:

  • Length: 316
  • Mass: 35110
  • Checksum: 574128C7ADCC51C0
  • Sequence:
  • MTQGKLSVAN KAPGTEGQQQ VHGEKKEAPA VPSAPPSYEE ATSGEGMKAG AFPPAPTAVP 
    LHPSWAYVDP SSSSSYDNGF PTGDHELFTT FSWDDQKVRR VFVRKVYTIL LIQLLVTLAV 
    VALFTFCDPV KDYVQANPGW YWASYAVFFA TYLTLACCSG PRRHFPWNLI LLTVFTLSMA 
    YLTGMLSSYY NTTSVLLCLG ITALVCLSVT VFSFQTKFDF TSCQGVLFVL LMTLFFSGLI 
    LAILLPFQYV PWLHAVYAAL GAGVFTLFLA LDTQLLMGNR RHSLSPEEYI FGALNIYLDI 
    IYIFTFFLQL FGTNRE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.