Details for: MON2

Gene ID: 23041

Symbol: MON2

Ensembl ID: ENSG00000061987

Description: MON2 homolog, regulator of endosome-to-Golgi trafficking

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 4.5
    Marker Score: 18,772
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.01
    Marker Score: 6,603
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.73
    Marker Score: 5,249
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.66
    Marker Score: 3,061
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.64
    Marker Score: 3,285
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.61
    Marker Score: 2,009
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.6
    Marker Score: 761
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.56
    Marker Score: 10,716
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.5
    Marker Score: 49,703
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.48
    Marker Score: 37,090
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.47
    Marker Score: 2,731
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.45
    Marker Score: 1,427
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.42
    Marker Score: 81,707
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 2.42
    Marker Score: 9,361
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.41
    Marker Score: 2,914
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.4
    Marker Score: 1,264
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.4
    Marker Score: 18,371
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.38
    Marker Score: 90,431
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.36
    Marker Score: 50,264
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.29
    Marker Score: 10,608
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.29
    Marker Score: 1,275
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.27
    Marker Score: 3,059
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.25
    Marker Score: 9,331
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.23
    Marker Score: 82,324
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.22
    Marker Score: 1,242
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.19
    Marker Score: 11,753
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.17
    Marker Score: 1,271
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.17
    Marker Score: 7,699
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.14
    Marker Score: 47,856
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.13
    Marker Score: 8,254
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.13
    Marker Score: 5,105
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.11
    Marker Score: 2,010
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.09
    Marker Score: 660
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.08
    Marker Score: 19,545
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.06
    Marker Score: 1,431
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 2.04
    Marker Score: 1,673
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.04
    Marker Score: 853
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.03
    Marker Score: 36,123
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.01
    Marker Score: 1,202
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.01
    Marker Score: 123,423
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2
    Marker Score: 634
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2
    Marker Score: 5,699
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.88
    Marker Score: 2,032
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.88
    Marker Score: 17,870
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 1.86
    Marker Score: 6,248
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.83
    Marker Score: 664
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.83
    Marker Score: 526
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.82
    Marker Score: 7,601
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.82
    Marker Score: 2,057
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.81
    Marker Score: 15,583
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.81
    Marker Score: 18,694
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.79
    Marker Score: 1,591
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.79
    Marker Score: 662
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.79
    Marker Score: 969
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.77
    Marker Score: 7,213
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.77
    Marker Score: 9,265
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.76
    Marker Score: 1,524
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.76
    Marker Score: 874
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.74
    Marker Score: 2,917
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.71
    Marker Score: 1,287
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.68
    Marker Score: 1,105
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.67
    Marker Score: 3,846
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.66
    Marker Score: 2,057
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.64
    Marker Score: 12,348
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.6
    Marker Score: 25,748
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.6
    Marker Score: 5,231
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.59
    Marker Score: 894
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.59
    Marker Score: 5,657
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.58
    Marker Score: 577
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.58
    Marker Score: 2,435
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.57
    Marker Score: 1,362
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.57
    Marker Score: 8,441
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.57
    Marker Score: 587
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.56
    Marker Score: 426
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.55
    Marker Score: 9,943
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.53
    Marker Score: 1,634
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.52
    Marker Score: 394
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.48
    Marker Score: 504
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.45
    Marker Score: 2,059
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.45
    Marker Score: 840
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.44
    Marker Score: 6,225
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.44
    Marker Score: 367
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.43
    Marker Score: 708
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.41
    Marker Score: 685
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.39
    Marker Score: 608
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.37
    Marker Score: 516
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.37
    Marker Score: 433
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.36
    Marker Score: 490
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.35
    Marker Score: 1,906
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.34
    Marker Score: 514
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.32
    Marker Score: 419
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.32
    Marker Score: 2,310
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 1.32
    Marker Score: 634
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.3
    Marker Score: 3,253
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.29
    Marker Score: 426
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.29
    Marker Score: 847
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.25
    Marker Score: 330
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.19
    Marker Score: 1,258
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.18
    Marker Score: 1,713
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.12
    Marker Score: 455

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular localization**: MON2 is primarily expressed in cells of the nervous system, including GABAergic neurons and ciliary muscle cells. Its expression is also observed in renal cells, suggesting a broader role in tissue homeostasis. 2. **Protein binding and transport**: The MON2 protein is involved in protein binding and transport, highlighting its potential role in regulating cellular processes such as endocytosis and exocytosis. 3. **Endosome-to-Golgi trafficking**: MON2 is specifically involved in regulating endosome-to-Golgi trafficking, a process critical for maintaining cellular homeostasis and proper protein folding. 4. **Significant expression in disease-relevant cell types**: MON2 is expressed in cells relevant to several immunological and neurological disorders, including GABAergic cortical interneurons and renal principal cells. **Pathways and Functions:** 1. **Golgi to endosome transport**: MON2 plays a crucial role in regulating the transport of proteins from the Golgi apparatus to early endosomes, a process essential for maintaining cellular homeostasis. 2. **Protein binding and transport**: The MON2 protein is involved in binding and transporting proteins, which is critical for regulating cellular processes such as endocytosis and exocytosis. 3. **Cytosol and early endosome membrane**: MON2 is also expressed in the cytosol and early endosome membrane, highlighting its potential role in regulating cellular processes such as protein degradation and recycling. 4. **Extracellular exosome**: MON2 is also involved in regulating the transport of proteins to the extracellular exosome, which is critical for maintaining tissue homeostasis and regulating immune responses. **Clinical Significance:** 1. **Immunological disorders**: MON2 has been implicated in the pathogenesis of several immunological disorders, including autoimmune diseases and inflammatory conditions. 2. **Neurological disorders**: MON2 is also expressed in cells relevant to several neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 3. **Cancer**: MON2 has been identified as a potential oncogene, with its overexpression associated with tumor progression and metastasis. 4. **Tissue homeostasis**: MON2 plays a critical role in maintaining tissue homeostasis, and its dysregulation has been implicated in several human diseases. In conclusion, the MON2 homolog gene plays a critical role in regulating endosome-to-Golgi trafficking and protein binding and transport. Its significant expression in disease-relevant cell types highlights its potential role in the pathogenesis of several immunological and neurological disorders. Further investigation into the role of MON2 in human disease is necessary to fully elucidate its clinical significance and to develop effective therapeutic strategies.

Genular Protein ID: 394692446

Symbol: MON2_HUMAN

Name: Protein MON2 homolog

UniProtKB Accession Codes:

Q7Z3U7 A5D8U7 A7E2Y0 B9EGP5 F8VWA6 F8W1Z6 Q86TA2 Q8N3I5 Q8NAI0 Q8NHE2 Q9UPW1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 RefSeq 4 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16219684

Title: Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis.

PubMed ID: 16219684

DOI: 10.1242/jcs.02599

PubMed ID: 16301316

Title: Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.

PubMed ID: 16301316

DOI: 10.1074/jbc.m510176200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30213940

Title: SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.

PubMed ID: 30213940

DOI: 10.1038/s41467-018-06114-3

Sequence Information:

  • Length: 1717
  • Mass: 190359
  • Checksum: A95DCDF2A69BC0D2
  • Sequence:
    • MSGTSSPEAV KKLLENMQSD LRALSLECKK KFPPVKEAAE SGIIKVKTIA ARNTEILAAL 
KENSSEVVQP FLMGCGTKEP KITQLCLAAI QRLMSHEVVS ETAAGNIINM LWQLMENSLE 
ELKLLQTVLV LLTTNTVVHD EALSKAIVLC FRLHFTKDNI TNNTAAATVR QVVTVVFERM 
VAEDERHRDI IEQPVLVQGN SNRRSVSTLK PCAKDAYMLF QDLCQLVNAD APYWLVGMTE 
MTRTFGLELL ESVLNDFPQV FLQHQEFSFL LKERVCPLVI KLFSPNIKFR QGSSTSSSPA 
PVEKPYFPIC MRLLRVVSVL IKQFYSLLVT ECEIFLSLLV KFLDADKPQW LRAVAVESIH 
RFCVQPQLLR SFCQSYDMKQ HSTKVFRDIV NALGSFIQSL FLVPPTGNPA TSNQAGNNNL 
GGSVSAPANS GMVGIGGGVT LLPAFEYRGT WIPILTITVQ GSAKATYLEM LDKVEPPTIP 
EGYAMSVAFH CLLDLVRGIT SMIEGELGEL ETECQTTTEE GSSPTQSTEQ QDLQSTSDQM 
DKEIVSRAVW EEMVNACWCG LLAALSLLLD ASTDEAATEN ILKAELTMAA LCGRLGLVTS 
RDAFITAICK GSLPPHYALT VLNTTTAATL SNKSYSVQGQ SVMMISPSSE SHQQVVAVGQ 
PLAVQPQGTV MLTSKNIQCM RTLLNLAHCH GAVLGTSWQL VLATLQHLVW ILGLKPSSGG 
ALKPGRAVEG PSTVLTTAVM TDLPVISNIL SRLFESSQYL DDVSLHHLIN ALCSLSLEAM 
DMAYGNNKEP SLFAVAKLLE TGLVNMHRIE ILWRPLTGHL LEVCQHPNSR MREWGAEALT 
SLIKAGLTFN HDPPLSQNQR LQLLLLNPLK EMSNINHPDI RLKQLECVLQ ILQSQGDSLG 
PGWPLVLGVM GAIRNDQGES LIRTAFQCLQ LVVTDFLPTM PCTCLQIVVD VAGSFGLHNQ 
ELNISLTSIG LLWNISDYFF QRGETIEKEL NKEEAAQQKQ AEEKGVVLNR PFHPAPPFDC 
LWLCLYAKLG ELCVDPRPAV RKSAGQTLFS TIGAHGTLLQ HSTWHTVIWK VLFHLLDRVR 
ESSTTADKEK IESGGGNILI HHSRDTAEKQ WAETWVLTLA GVARIFNTRR YLLQPLGDFS 
RAWDVLLDHI QSAALSKNNE VSLAALKSFQ EILQIVSPVR DSDKPETPPV VNVPVPVLIG 
PISGMSRPFV RTDSIGEKLG RYSSSEPPIV TDELEDLNLW WAAWNTWYRI GSESTKPPIT 
FDKLTFIPSQ PFLTALIQIF PALYQHIKTG FNMDDLQKLG VILHSAISVP ISSDASPFIL 
PSYTEAVLTS LQEAVLTALD VLQKAICVGP ENMQIMYPAI FDQLLAFVEF SCKPPQYGQL 
ETKHIANAKY NQIQLFAPAE WVALNYVPFA ERSLEVVVDL YQKTACHKAV VNEKVLQNII 
KTLRVPLSLK YSCPSESTWK LAVSSLLRVL SIGLPVARQH ASSGKFDSMW PELANTFEDF 
LFTKSIPPDN LSIQEFQRNE NIDVEVVQLI SNEILPYANF IPKEFVGQIM TMLNKGSIHS 
QSSSFTEAEI DIRLREEFSK MCFETLLQFS FSNKVTTPQE GYISRMALSV LLKRSQDVLH 
RYIEDERLSG KCPLPRQQVT EIIFVLKAVS TLIDSLKKTQ PENVDGNTWA QVIALYPTLV 
ECITCSSSEV CSALKEALVP FKDFMQPPAS RVQNGES

Genular Protein ID: 1779365505

Symbol: B7ZM73_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZM73

Database IDs:

ARBA 4 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 GenomeRNAi 1 IntAct 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 8 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1688
  • Mass: 187319
  • Checksum: 3070BD221D8B3EBA
  • Sequence:
    • MSGTSSPEAV KKLLENMQSD LRALSLECKK KFPPVKEAAE SGIIKVKTIA ARNTEILAAL 
KENSSEVVQP FLMGCGTKEP KITQLCLAAI QRLMSHEVVS ETAAGNIINM LWQLMENSLE 
ELKLLQTVLV LLTTNTVVHD EALSKAIVLC FRLHFTKDNI TNNTAAATVR QVVTVVFERM 
VAEDERHRDI IEQPVLVQGN SNRRSVSTLK PCAKDAYMLF QDLCQLVNAD APYWLVGMTE 
MTRTFGLELL ESVLNDFPQV FLQHQEFSFL LKERVCPLVI KLFSPNIKFR QGSSTSSSPA 
PVEKPYFPIC MRLLRVVSVL IKQFYSLLVT ECEIFLSLLV KFLDADKPQW LRAVAVESIH 
RFCVQPQLLR SFCQSYDMKQ HSTKVFRDIV NALGSFIQSL FLVPPTGNPA TSNQAGNNNL 
GGSVSAPANS GMVGIGGGVT LLPAFEYRGT WIPILTITVQ GSAKATYLEM LDKVEPPTIP 
EGYAMSVAFH CLLDLVRGIT SMIEGELGEL ETECQTTTEE GSSPTQSTEQ QDLQSTSDQM 
DKEIVSRAVW EEMVNACWCG LLAALSLLLD ASTDEAATEN ILKAELTMAA LCGRLGLVTS 
RDAFITAICK AYSVQGQSVM MISPSSESHQ QVVAVGQPLA VQPQGTVMLT SKNIQCMRTL 
LNLAHCHGAV LGTSWQLVLA TLQHLVWILG LKPSSGGALK PGRAVEGPST VLTTAVMTDL 
PVISNILSRL FESSQYLDDV SLHHLINALC SLSLEAMDMA YGNNKEPSLF AVAKLLETGL 
VNMHRIEILW RPLTGHLLEV CQHPNSRMRE WGAEALTSLI KAGLTFNHDP PLSQNQRLQL 
LLLNPLKEMS NINHPDIRLK QLECVLQILQ SQGDSLGPGW PLVLGVMGAI RNDQGESLIR 
TAFQCLQLVV TDFLPTMPCT CLQIVVDVAG SFGLHNQELN ISLTSIGLLW NISDYFFQRG 
ETIEKELNKE EAAQQKQAEE KGVVLNRPFH PAPPFDCLWL CLYAKLGELC VDPRPAVRKS 
AGQTLFSTIG AHGTLLQHST WHTVIWKVLF HLLDRVRESS TTADKEKIQS GGGNILIHHS 
RDTAEKQWAE TWVLTLAGVA RIFNTRRYLL QPLGDFSRAW DVLLDHIQSA ALSKNNEVSL 
AALKSFQEIL QIVSPVRDSD KPETPPVVNV PVPVLIGPIS GMSRPFVRTD SIGEKLGRYS 
SSEPPIVTDE LEDLNLWWAA WNTWYRIGSE STKPPITFDK LTFIPSQPFL TALIQIFPAL 
YQHIKTGFNM DDLQKLGVIL HSAISVPISS DASPFILPSY TEAVLTSLQE AVLTALDVLQ 
KAICVGPENM QIMYPAIFDQ LLAFVEFSCK PPQYGQLETK HIANAKYNQA EWVALNYVPF 
AERSLEVVVD LYQKTACHKA VVNEKVLQNI IKTLRVPLSL KYSCPSESTW KLAVSSLLRV 
LSIGLPVARQ HASSGKFDSM WPELANTFED FLFTKSIPPD NLSIQEFQRN ENIDVEVVQL 
ISNEILPYAN FIPKEFVGQI MTMLNKGSIH SQSSSFTEAE IDIRLREEFS KMCFETLLQF 
SFSNKVTTPQ EGYISRMALS VLLKRSQDVL HRYIEDERLS GKCPLPRQQV TEIIFVLKAV 
STLIDSLKKT QPENVDGNTW AQVIALYPTL VECITCSSSE VCSALKEALV PFKDFMQPPA 
SRVQNGES

Genular Protein ID: 2148699682

Symbol: A0A286YFF8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A286YFF8

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 1 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 8 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1718
  • Mass: 190487
  • Checksum: BE30F73F0CAE4764
  • Sequence:
    • MSGTSSPEAV KKLLENMQSD LRALSLECKK KFPPVKEAAE SGIIKVKTIA ARNTEILAAL 
KENSSEVVQP FLMGCGTKEP KITQLCLAAI QRLMSHEVVS ETAAGNIINM LWQLMENSLE 
ELKLLQTVLV LLTTNTVVHD EALSKAIVLC FRLHFTKDNI TNNTAAATVR QVVTVVFERM 
VAEDERHRDI IEQPVLVQGN SNRRSVSTLK PCAKDAYMLF QDLCQLVNAD APYWLVGMTE 
MTRTFGLELL ESVLNDFPQV FLQHQEFSFL LKERVCPLVI KLFSPNIKFR QGSSTSSSPA 
PVEKPYFPIC MRLLRVVSVL IKQFYSLLVT ECEIFLSLLV KFLDADKPQW LRAVAVESIH 
RFCVQPQLLR SFCQSYDMKQ HSTKVFRDIV NALGSFIQSL FLVPPTGNPA TSNQAGNNNL 
GGSVSAPANS GMVGIGGGVT LLPAFEYRGT WIPILTITVQ GSAKATYLEM LDKVEPPTIP 
EGYAMSVAFH CLLDLVRGIT SMIEGELGEL ETECQTTTEE GSSPTQSTEQ QDLQSTSDQM 
DKEIVSRAVW EEMVNACWCG LLAALSLLLD ASTDEAATEN ILKAELTMAA LCGRLGLVTS 
RDAFITAICK GSLPPHYALT VLNTTTAATL SNKSYSVQGQ SVMMISPSSE SHQQVVAVGQ 
PLAVQPQGTV MLTSKNIQCM RTLLNLAHCH GAVLGTSWQL VLATLQHLVW ILGLKPSSGG 
ALKPGRAVEG PSTVLTTAVM TDLPVISNIL SRLFESSQYL DDVSLHHLIN ALCSLSLEAM 
DMAYGNNKEP SLFAVAKLLE TGLVNMHRIE ILWRPLTGHL LEKVCQHPNS RMREWGAEAL 
TSLIKAGLTF NHDPPLSQNQ RLQLLLLNPL KEMSNINHPD IRLKQLECVL QILQSQGDSL 
GPGWPLVLGV MGAIRNDQGE SLIRTAFQCL QLVVTDFLPT MPCTCLQIVV DVAGSFGLHN 
QELNISLTSI GLLWNISDYF FQRGETIEKE LNKEEAAQQK QAEEKGVVLN RPFHPAPPFD 
CLWLCLYAKL GELCVDPRPA VRKSAGQTLF STIGAHGTLL QHSTWHTVIW KVLFHLLDRV 
RESSTTADKE KIESGGGNIL IHHSRDTAEK QWAETWVLTL AGVARIFNTR RYLLQPLGDF 
SRAWDVLLDH IQSAALSKNN EVSLAALKSF QEILQIVSPV RDSDKPETPP VVNVPVPVLI 
GPISGMSRPF VRTDSIGEKL GRYSSSEPPI VTDELEDLNL WWAAWNTWYR IGSESTKPPI 
TFDKLTFIPS QPFLTALIQI FPALYQHIKT GFNMDDLQKL GVILHSAISV PISSDASPFI 
LPSYTEAVLT SLQEAVLTAL DVLQKAICVG PENMQIMYPA IFDQLLAFVE FSCKPPQYGQ 
LETKHIANAK YNQIQLFAPA EWVALNYVPF AERSLEVVVD LYQKTACHKA VVNEKVLQNI 
IKTLRVPLSL KYSCPSESTW KLAVSSLLRV LSIGLPVARQ HASSGKFDSM WPELANTFED 
FLFTKSIPPD NLSIQEFQRN ENIDVEVVQL ISNEILPYAN FIPKEFVGQI MTMLNKGSIH 
SQSSSFTEAE IDIRLREEFS KMCFETLLQF SFSNKVTTPQ EGYISRMALS VLLKRSQDVL 
HRYIEDERLS GKCPLPRQQV TEIIFVLKAV STLIDSLKKT QPENVDGNTW AQVIALYPTL 
VECITCSSSE VCSALKEALV PFKDFMQPPA SRVQNGES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.