Details for: TNIK

Gene ID: 23043

Symbol: TNIK

Ensembl ID: ENSG00000154310

Description: TRAF2 and NCK interacting kinase

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 5.69
    Marker Score: 19,069
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 5.49
    Marker Score: 3,611
  • Cell Name: granule cell (CL0000120)
    Fold Change: 5.12
    Marker Score: 38,576
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 4.96
    Marker Score: 29,835
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 4.55
    Marker Score: 24,434
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 4.47
    Marker Score: 23,455
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 4.45
    Marker Score: 10,230
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 4.25
    Marker Score: 143,412
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 3.72
    Marker Score: 1,786
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 3.61
    Marker Score: 80,608
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.5
    Marker Score: 62,195
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.5
    Marker Score: 14,637
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.24
    Marker Score: 69,187
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.22
    Marker Score: 7,059
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.04
    Marker Score: 14,082
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.83
    Marker Score: 1,641
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.83
    Marker Score: 56,194
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.75
    Marker Score: 871
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.64
    Marker Score: 20,227
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.63
    Marker Score: 99,746
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.62
    Marker Score: 2,274
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.61
    Marker Score: 7,459
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.6
    Marker Score: 759
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.54
    Marker Score: 10,526
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.47
    Marker Score: 1,033
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.44
    Marker Score: 1,358
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.41
    Marker Score: 88,879
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.4
    Marker Score: 921
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.37
    Marker Score: 5,681
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 2.32
    Marker Score: 2,897
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.26
    Marker Score: 713
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.22
    Marker Score: 2,688
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 2.2
    Marker Score: 1,759
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 2.18
    Marker Score: 1,657
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.15
    Marker Score: 3,605
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.15
    Marker Score: 20,178
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.13
    Marker Score: 8,219
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.06
    Marker Score: 2,551
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.04
    Marker Score: 125,631
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.01
    Marker Score: 7,144
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.97
    Marker Score: 1,104
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.95
    Marker Score: 7,951
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.91
    Marker Score: 18,113
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.88
    Marker Score: 4,708
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.87
    Marker Score: 16,033
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.86
    Marker Score: 29,884
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.83
    Marker Score: 500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.66
    Marker Score: 24,868
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.61
    Marker Score: 1,394
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.61
    Marker Score: 2,486
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.6
    Marker Score: 3,767
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.59
    Marker Score: 576
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.54
    Marker Score: 898
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 1.49
    Marker Score: 451
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.47
    Marker Score: 543
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.46
    Marker Score: 1,571
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167,141
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.44
    Marker Score: 415
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.4
    Marker Score: 475
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.34
    Marker Score: 806
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.33
    Marker Score: 20,845
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.27
    Marker Score: 4,525
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.24
    Marker Score: 624
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.23
    Marker Score: 5,142
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.18
    Marker Score: 510
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.18
    Marker Score: 609
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.15
    Marker Score: 293
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.13
    Marker Score: 7,368
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.13
    Marker Score: 422
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.12
    Marker Score: 1,293
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.12
    Marker Score: 59,400
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.11
    Marker Score: 743
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.1
    Marker Score: 1,480
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.09
    Marker Score: 3,452
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.08
    Marker Score: 440
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.08
    Marker Score: 347
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.05
    Marker Score: 1,273
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.03
    Marker Score: 268
  • Cell Name: basophil (CL0000767)
    Fold Change: 1.03
    Marker Score: 490
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.01
    Marker Score: 954
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.01
    Marker Score: 2,048
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1
    Marker Score: 660
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,715
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,942
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 0.99
    Marker Score: 811
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,396
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.98
    Marker Score: 1,878
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.98
    Marker Score: 395
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.96
    Marker Score: 1,325
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.96
    Marker Score: 4,123
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 491
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.95
    Marker Score: 668
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,406
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 446
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.93
    Marker Score: 678
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.93
    Marker Score: 1,509
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.91
    Marker Score: 1,260
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,717
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.9
    Marker Score: 847
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: 0.9
    Marker Score: 994

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TNIK is a serine/threonine kinase that exhibits high specificity for phosphorylating and regulating various proteins. Its interaction with TRAF2 and NCK proteins is crucial for its function, as it enables the kinase to bind to and phosphorylate downstream targets. TNIK's kinase activity is also modulated by phosphorylation itself, creating a feedback loop that fine-tunes its activity in response to cellular signals. The gene's expression is widespread, with notable expression in cells involved in the central nervous system (CNS), including neurons and astrocytes. **Pathways and Functions:** TNIK is involved in various signaling pathways, including: 1. **Actin Cytoskeleton Organization:** TNIK regulates the dynamics of the actin cytoskeleton, which is essential for cellular movement, shape, and signaling. 2. **Apical Plasma Membrane:** TNIK's interaction with TRAF2 and NCK proteins is crucial for the regulation of the apical plasma membrane, which is involved in cellular responses to stimuli. 3. **Cellular Responses to Stimuli:** TNIK's kinase activity is essential for the regulation of cellular responses to stimuli, including stress and oxidative stress-induced senescence. 4. **Intracellular Signal Transduction:** TNIK's interaction with downstream targets modulates intracellular signal transduction, influencing the regulation of various cellular processes. 5. **Wnt Signaling Pathway:** TNIK's kinase activity is also involved in the regulation of the Wnt signaling pathway, which plays a critical role in embryonic development and tissue homeostasis. **Clinical Significance:** Dysregulation of TNIK has been implicated in various diseases, including: 1. **Neurodegenerative Disorders:** TNIK's role in regulating the actin cytoskeleton and intracellular signaling pathways positions it as a potential target for the treatment of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. 2. **Cancer:** TNIK's involvement in the regulation of the Wnt signaling pathway and cellular responses to stress makes it a potential target for cancer therapy. 3. **Cardiac Disease:** TNIK's expression in cardiac fibroblasts and its role in regulating the actin cytoskeleton position it as a potential target for the treatment of cardiac disease. In conclusion, TNIK is a complex gene that plays a critical role in various cellular processes, including actin cytoskeleton organization, cellular responses to stimuli, and regulation of signaling pathways. Its dysregulation has been implicated in various diseases, making it a potential target for the treatment of neurodegenerative disorders, cancer, and cardiac disease. Further research is needed to fully elucidate the functions of TNIK and its role in human disease.

Genular Protein ID: 2560511556

Symbol: TNIK_HUMAN

Name: TRAF2 and NCK-interacting protein kinase

UniProtKB Accession Codes:

Q9UKE5 A7E2A3 A8K4U1 D3DNQ6 O60298 Q8WUY7 Q9UKD8 Q9UKD9 Q9UKE0 Q9UKE1 Q9UKE2 Q9UKE3 Q9UKE4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 8 CDD 1 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 3 EMBL 21 EPD 1 Ensembl 8 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 8 PRO 1 PROSITE 4 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 Pumba 1 RNAct 1 Reactome 1 RefSeq 8 Rhea 6 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10521462

Title: TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton.

PubMed ID: 10521462

DOI: 10.1074/jbc.274.43.30729

PubMed ID: 9628581

Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9628581

DOI: 10.1093/dnares/5.1.31

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15342639

Title: The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton.

PubMed ID: 15342639

DOI: 10.1074/jbc.m406370200

PubMed ID: 18930710

Title: MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

PubMed ID: 18930710

DOI: 10.1016/j.bbrc.2008.10.038

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19061864

Title: Rap2 function requires palmitoylation and recycling endosome localization.

PubMed ID: 19061864

DOI: 10.1016/j.bbrc.2008.11.107

PubMed ID: 19816403

Title: The kinase TNIK is an essential activator of Wnt target genes.

PubMed ID: 19816403

DOI: 10.1038/emboj.2009.285

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20159449

Title: Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.

PubMed ID: 20159449

DOI: 10.1016/j.neuron.2010.01.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21690388

Title: Smad inhibition by the Ste20 kinase Misshapen.

PubMed ID: 21690388

DOI: 10.1073/pnas.1104128108

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27106596

Title: A null mutation in TNIK defines a novel locus for intellectual disability.

PubMed ID: 27106596

DOI: 10.1007/s00439-016-1671-9

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1360
  • Mass: 154943
  • Checksum: 3590BC2905A72C3D
  • Sequence:
    • MASDSPARSL DEIDLSALRD PAGIFELVEL VGNGTYGQVY KGRHVKTGQL AAIKVMDVTG 
DEEEEIKQEI NMLKKYSHHR NIATYYGAFI KKNPPGMDDQ LWLVMEFCGA GSVTDLIKNT 
KGNTLKEEWI AYICREILRG LSHLHQHKVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR 
TVGRRNTFIG TPYWMAPEVI ACDENPDATY DFKSDLWSLG ITAIEMAEGA PPLCDMHPMR 
ALFLIPRNPA PRLKSKKWSK KFQSFIESCL VKNHSQRPAT EQLMKHPFIR DQPNERQVRI 
QLKDHIDRTK KKRGEKDETE YEYSGSEEEE EENDSGEPSS ILNLPGESTL RRDFLRLQLA 
NKERSEALRR QQLEQQQREN EEHKRQLLAE RQKRIEEQKE QRRRLEEQQR REKELRKQQE 
REQRRHYEEQ MRREEERRRA EHEQEYIRRQ LEEEQRQLEI LQQQLLHEQA LLLEYKRKQL 
EEQRQAERLQ RQLKQERDYL VSLQHQRQEQ RPVEKKPLYH YKEGMSPSEK PAWAKEVEER 
SRLNRQSSPA MPHKVANRIS DPNLPPRSES FSISGVQPAR TPPMLRPVDP QIPHLVAVKS 
QGPALTASQS VHEQPTKGLS GFQEALNVTS HRVEMPRQNS DPTSENPPLP TRIEKFDRSS 
WLRQEEDIPP KVPQRTTSIS PALARKNSPG NGSALGPRLG SQPIRASNPD LRRTEPILES 
PLQRTSSGSS SSSSTPSSQP SSQGGSQPGS QAGSSERTRV RANSKSEGSP VLPHEPAKVK 
PEESRDITRP SRPASYKKAI DEDLTALAKE LRELRIEETN RPMKKVTDYS SSSEESESSE 
EEEEDGESET HDGTVAVSDI PRLIPTGAPG SNEQYNVGMV GTHGLETSHA DSFSGSISRE 
GTLMIRETSG EKKRSGHSDS NGFAGHINLP DLVQQSHSPA GTPTEGLGRV STHSQEMDSG 
TEYGMGSSTK ASFTPFVDPR VYQTSPTDED EEDEESSAAA LFTSELLRQE QAKLNEARKI 
SVVNVNPTNI RPHSDTPEIR KYKKRFNSEI LCAALWGVNL LVGTENGLML LDRSGQGKVY 
NLINRRRFQQ MDVLEGLNVL VTISGKKNKL RVYYLSWLRN RILHNDPEVE KKQGWITVGD 
LEGCIHYKVV KYERIKFLVI ALKNAVEIYA WAPKPYHKFM AFKSFADLQH KPLLVDLTVE 
EGQRLKVIFG SHTGFHVIDV DSGNSYDIYI PSHIQGNITP HAIVILPKTD GMEMLVCYED 
EGVYVNTYGR ITKDVVLQWG EMPTSVAYIH SNQIMGWGEK AIEIRSVETG HLDGVFMHKR 
AQRLKFLCER NDKVFFASVR SGGSSQVFFM TLNRNSMMNW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.