Details for: PDS5B

Gene ID: 23047

Symbol: PDS5B

Ensembl ID: ENSG00000083642

Description: PDS5 cohesin associated factor B

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.69
    Marker Score: 3,092
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 2.58
    Marker Score: 8,646
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.56
    Marker Score: 19,658
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 2.55
    Marker Score: 13,387
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.54
    Marker Score: 50,531
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.5
    Marker Score: 11,552
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.48
    Marker Score: 94,048
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.45
    Marker Score: 4,717
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.37
    Marker Score: 80,171
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 2.36
    Marker Score: 1,133
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.29
    Marker Score: 2,769
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.26
    Marker Score: 1,266
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.26
    Marker Score: 83,270
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.25
    Marker Score: 3,022
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.18
    Marker Score: 9,079
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.16
    Marker Score: 46,195
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.15
    Marker Score: 2,052
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.11
    Marker Score: 3,543
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.09
    Marker Score: 1,218
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.09
    Marker Score: 31,185
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.07
    Marker Score: 1,234
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.06
    Marker Score: 8,534
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.05
    Marker Score: 2,558
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.05
    Marker Score: 1,198
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.03
    Marker Score: 4,449
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.02
    Marker Score: 7,807
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.01
    Marker Score: 18,941
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2
    Marker Score: 123,225
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.99
    Marker Score: 1,108
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.98
    Marker Score: 5,644
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.97
    Marker Score: 577
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.97
    Marker Score: 1,705
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.94
    Marker Score: 2,725
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.93
    Marker Score: 10,349
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.92
    Marker Score: 1,702
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.92
    Marker Score: 2,316
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.9
    Marker Score: 14,333
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.9
    Marker Score: 730
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.9
    Marker Score: 18,016
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.83
    Marker Score: 15,702
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.83
    Marker Score: 4,373
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.8
    Marker Score: 753
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.79
    Marker Score: 566
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.74
    Marker Score: 575
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.73
    Marker Score: 7,239
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.73
    Marker Score: 17,850
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.69
    Marker Score: 1,173
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.69
    Marker Score: 6,877
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.62
    Marker Score: 802
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.6
    Marker Score: 1,235
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.6
    Marker Score: 3,684
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.6
    Marker Score: 1,769
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.55
    Marker Score: 770
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.55
    Marker Score: 1,164
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.54
    Marker Score: 2,379
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.54
    Marker Score: 399
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.53
    Marker Score: 27,213
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.52
    Marker Score: 51,554
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.51
    Marker Score: 1,632
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.5
    Marker Score: 432
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.5
    Marker Score: 869
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.5
    Marker Score: 2,174
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.49
    Marker Score: 1,848
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.48
    Marker Score: 468
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.45
    Marker Score: 16,322
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.43
    Marker Score: 364
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.43
    Marker Score: 940
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.4
    Marker Score: 1,588
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.38
    Marker Score: 437
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.35
    Marker Score: 701
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.35
    Marker Score: 733
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.35
    Marker Score: 21,667
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.35
    Marker Score: 368
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.34
    Marker Score: 1,897
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.32
    Marker Score: 3,593
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.29
    Marker Score: 1,116
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.28
    Marker Score: 1,364
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.27
    Marker Score: 11,187
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.27
    Marker Score: 474
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.26
    Marker Score: 1,933
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.25
    Marker Score: 425
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.24
    Marker Score: 1,169
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.23
    Marker Score: 1,248
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.22
    Marker Score: 459
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.21
    Marker Score: 590
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.21
    Marker Score: 447
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.21
    Marker Score: 18,886
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.21
    Marker Score: 630
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.19
    Marker Score: 483
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.19
    Marker Score: 274
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.19
    Marker Score: 664
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.19
    Marker Score: 713
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.19
    Marker Score: 740
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.18
    Marker Score: 428
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.18
    Marker Score: 620
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.17
    Marker Score: 26,173
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.17
    Marker Score: 7,589
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.16
    Marker Score: 1,062
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.15
    Marker Score: 1,223
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.15
    Marker Score: 1,110

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PDS5B is a member of the PDS5 family of cohesin-associated factors, which are essential for maintaining genome stability and regulating cell proliferation. It is a small, highly conserved protein that interacts with the cohesin complex, specifically with the SMC3 and SMC1 subunits. PDS5B is highly expressed in cells that undergo rapid proliferation, such as neurons and kidney interstitial fibroblasts. Its expression is also observed in cells of the central nervous system (CNS), including inhibitory interneurons and Purkinje cells. **Pathways and Functions:** PDS5B is involved in several key pathways that regulate genome stability and cell proliferation: 1. **Cohesin loading onto chromatin:** PDS5B interacts with the cohesin complex to load sister chromatids onto chromatin, ensuring proper chromosome segregation during mitosis. 2. **Establishment of sister chromatid cohesion:** PDS5B helps to establish and maintain sister chromatid cohesion, preventing improper chromosome separation and ensuring accurate genome replication. 3. **Resolution of sister chromatid cohesion:** PDS5B is also involved in the resolution of sister chromatid cohesion, allowing for proper chromosome segregation during mitosis. 4. **Negative regulation of cell population proliferation:** PDS5B acts as a negative regulator of cell population proliferation, preventing excessive cell growth and tumorigenesis. **Clinical Significance:** Dysregulation of PDS5B has been implicated in various diseases, including: 1. **Cancer:** PDS5B mutations have been observed in various types of cancer, including breast, lung, and colon cancer. Its dysregulation can lead to genomic instability and tumorigenesis. 2. **Neurodegenerative disorders:** PDS5B has been implicated in neurodegenerative disorders, including Alzheimer's disease and amyotrophic lateral sclerosis (ALS). Its dysregulation can lead to impaired genome stability and neuronal dysfunction. 3. **Neurodevelopmental disorders:** PDS5B has also been implicated in neurodevelopmental disorders, including autism spectrum disorder (ASD) and schizophrenia. Its dysregulation can lead to impaired neuronal development and function. In conclusion, PDS5B plays a crucial role in maintaining genome stability and regulating cell proliferation. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding its function in normal cellular processes and its potential as a therapeutic target for disease prevention and treatment.

Genular Protein ID: 227625071

Symbol: PDS5B_HUMAN

Name: Sister chromatid cohesion protein PDS5 homolog B

UniProtKB Accession Codes:

Q9NTI5 Q5R3S3 Q5W0K8 Q6NSC3 Q8IXT6 Q9H5N8 Q9Y2I5 Q9Y451

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 16 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 4 RefSeq 2 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9459187

Title: Expression of novel genes linked to the androgen-induced, proliferative shutoff in prostate cancer cells.

PubMed ID: 9459187

DOI: 10.1016/s0960-0760(97)00122-2

PubMed ID: 10215036

Title: Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.

PubMed ID: 10215036

DOI: 10.1016/s0960-0760(98)00165-4

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10963680

Title: Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator.

PubMed ID: 10963680

DOI: 10.1073/pnas.97.18.10185

PubMed ID: 15855230

Title: Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

PubMed ID: 15855230

DOI: 10.1242/jcs.02355

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19696148

Title: Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1.

PubMed ID: 19696148

DOI: 10.1101/gad.1844309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21111234

Title: Sororin mediates sister chromatid cohesion by antagonizing wapl.

PubMed ID: 21111234

DOI: 10.1016/j.cell.2010.10.031

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1447
  • Mass: 164667
  • Checksum: 145C30308EA3EFD5
  • Sequence:
    • MAHSKTRTND GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE EEKELYLNLA 
LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP DKLKDIFMFI TRQLKGLEDT 
KSPQFNRYFY LLENIAWVKS YNICFELEDS NEIFTQLYRT LFSVINNGHN QKVHMHMVDL 
MSSIICEGDT VSQELLDTVL VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV 
LMLGKTSISD LSEHVFDLIL ELYNIDSHLL LSVLPQLEFK LKSNDNEERL QVVKLLAKMF 
GAKDSELASQ NKPLWQCYLG RFNDIHVPIR LECVKFASHC LMNHPDLAKD LTEYLKVRSH 
DPEEAIRHDV IVSIVTAAKK DILLVNDHLL NFVRERTLDK RWRVRKEAMM GLAQIYKKYA 
LQSAAGKDAA KQIAWIKDKL LHIYYQNSID DRLLVERIFA QYMVPHNLET TERMKCLYYL 
YATLDLNAVK ALNEMWKCQN LLRHQVKDLL DLIKQPKTDA SVKAIFSKVM VITRNLPDPG 
KAQDFMKKFT QVLEDDEKIR KQLEVLVSPT CSCKQAEGCV REITKKLGNP KQPTNPFLEM 
IKFLLERIAP VHIDTESISA LIKQVNKSID GTADDEDEGV PTDQAIRAGL ELLKVLSFTH 
PISFHSAETF ESLLACLKMD DEKVAEAALQ IFKNTGSKIE EDFPHIRSAL LPVLHHKSKK 
GPPRQAKYAI HCIHAIFSSK ETQFAQIFEP LHKSLDPSNL EHLITPLVTI GHIALLAPDQ 
FAAPLKSLVA TFIVKDLLMN DRLPGKKTTK LWVPDEEVSP ETMVKIQAIK MMVRWLLGMK 
NNHSKSGTST LRLLTTILHS DGDLTEQGKI SKPDMSRLRL AAGSAIVKLA QEPCYHEIIT 
LEQYQLCALA INDECYQVRQ VFAQKLHKGL SRLRLPLEYM AICALCAKDP VKERRAHARQ 
CLVKNINVRR EYLKQHAAVS EKLLSLLPEY VVPYTIHLLA HDPDYVKVQD IEQLKDVKEC 
LWFVLEILMA KNENNSHAFI RKMVENIKQT KDAQGPDDAK MNEKLYTVCD VAMNIIMSKS 
TTYSLESPKD PVLPARFFTQ PDKNFSNTKN YLPPEMKSFF TPGKPKTTNV LGAVNKPLSS 
AGKQSQTKSS RMETVSNASS SSNPSSPGRI KGRLDSSEMD HSENEDYTMS SPLPGKKSDK 
RDDSDLVRSE LEKPRGRKKT PVTEQEEKLG MDDLTKLVQE QKPKGSQRSR KRGHTASESD 
EQQWPEEKRL KEDILENEDE QNSPPKKGKR GRPPKPLGGG TPKEEPTMKT SKKGSKKKSG 
PPAPEEEEEE ERQSGNTEQK SKSKQHRVSR RAQQRAESPE SSAIESTQST PQKGRGRPSK 
TPSPSQPKKN VRVGRSKQAA TKENDSSEEV DVFQGSSPVD DIPQEETEEE EVSTVNVRRR 
SAKRERR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.