Details for: PDS5B
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.69
Marker Score: 3,092 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 2.58
Marker Score: 8,646 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.56
Marker Score: 19,658 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.55
Marker Score: 13,387 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.54
Marker Score: 50,531 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.5
Marker Score: 11,552 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.48
Marker Score: 94,048 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.45
Marker Score: 4,717 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.37
Marker Score: 80,171 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 2.36
Marker Score: 1,133 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.29
Marker Score: 2,769 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.26
Marker Score: 1,266 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.26
Marker Score: 83,270 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.25
Marker Score: 3,022 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.18
Marker Score: 9,079 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.16
Marker Score: 46,195 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.15
Marker Score: 2,052 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.11
Marker Score: 3,543 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.09
Marker Score: 1,218 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.09
Marker Score: 31,185 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.07
Marker Score: 1,234 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.06
Marker Score: 8,534 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.05
Marker Score: 2,558 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.05
Marker Score: 1,198 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.03
Marker Score: 4,449 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.02
Marker Score: 7,807 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.01
Marker Score: 18,941 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2
Marker Score: 123,225 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.99
Marker Score: 1,108 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.98
Marker Score: 5,644 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.97
Marker Score: 577 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.97
Marker Score: 1,705 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.94
Marker Score: 2,725 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.93
Marker Score: 10,349 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.92
Marker Score: 1,702 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.92
Marker Score: 2,316 - Cell Name: granule cell (CL0000120)
Fold Change: 1.9
Marker Score: 14,333 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.9
Marker Score: 730 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.9
Marker Score: 18,016 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.83
Marker Score: 15,702 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.83
Marker Score: 4,373 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.8
Marker Score: 753 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.79
Marker Score: 566 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 1.74
Marker Score: 575 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.73
Marker Score: 7,239 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.73
Marker Score: 17,850 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.69
Marker Score: 1,173 - Cell Name: neuron (CL0000540)
Fold Change: 1.69
Marker Score: 6,877 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.62
Marker Score: 802 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.6
Marker Score: 1,235 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.6
Marker Score: 3,684 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.6
Marker Score: 1,769 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.55
Marker Score: 770 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.55
Marker Score: 1,164 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.54
Marker Score: 2,379 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.54
Marker Score: 399 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.53
Marker Score: 27,213 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.52
Marker Score: 51,554 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.51
Marker Score: 1,632 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.5
Marker Score: 432 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.5
Marker Score: 869 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.5
Marker Score: 2,174 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.49
Marker Score: 1,848 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.48
Marker Score: 468 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.45
Marker Score: 16,322 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.43
Marker Score: 364 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.43
Marker Score: 940 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.4
Marker Score: 1,588 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.38
Marker Score: 437 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.35
Marker Score: 701 - Cell Name: contractile cell (CL0000183)
Fold Change: 1.35
Marker Score: 733 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.35
Marker Score: 21,667 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.35
Marker Score: 368 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.34
Marker Score: 1,897 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.32
Marker Score: 3,593 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.29
Marker Score: 1,116 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.28
Marker Score: 1,364 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.27
Marker Score: 11,187 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.27
Marker Score: 474 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.26
Marker Score: 1,933 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.25
Marker Score: 425 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1.24
Marker Score: 1,169 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.23
Marker Score: 1,248 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.22
Marker Score: 459 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.21
Marker Score: 590 - Cell Name: podocyte (CL0000653)
Fold Change: 1.21
Marker Score: 447 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.21
Marker Score: 18,886 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.21
Marker Score: 630 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.19
Marker Score: 483 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.19
Marker Score: 274 - Cell Name: fat cell (CL0000136)
Fold Change: 1.19
Marker Score: 664 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.19
Marker Score: 713 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.19
Marker Score: 740 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.18
Marker Score: 428 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.18
Marker Score: 620 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.17
Marker Score: 26,173 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.17
Marker Score: 7,589 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.16
Marker Score: 1,062 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.15
Marker Score: 1,223 - Cell Name: pro-B cell (CL0000826)
Fold Change: 1.15
Marker Score: 1,110
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 227625071
Symbol: PDS5B_HUMAN
Name: Sister chromatid cohesion protein PDS5 homolog B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9459187
Title: Expression of novel genes linked to the androgen-induced, proliferative shutoff in prostate cancer cells.
PubMed ID: 9459187
PubMed ID: 10215036
Title: Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.
PubMed ID: 10215036
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10963680
Title: Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator.
PubMed ID: 10963680
PubMed ID: 15855230
Title: Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.
PubMed ID: 15855230
DOI: 10.1242/jcs.02355
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 19367720
Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
PubMed ID: 19367720
DOI: 10.1021/pr800500r
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19696148
Title: Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1.
PubMed ID: 19696148
DOI: 10.1101/gad.1844309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21111234
Title: Sororin mediates sister chromatid cohesion by antagonizing wapl.
PubMed ID: 21111234
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1447
- Mass: 164667
- Checksum: 145C30308EA3EFD5
- Sequence:
MAHSKTRTND GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE EEKELYLNLA LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP DKLKDIFMFI TRQLKGLEDT KSPQFNRYFY LLENIAWVKS YNICFELEDS NEIFTQLYRT LFSVINNGHN QKVHMHMVDL MSSIICEGDT VSQELLDTVL VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV LMLGKTSISD LSEHVFDLIL ELYNIDSHLL LSVLPQLEFK LKSNDNEERL QVVKLLAKMF GAKDSELASQ NKPLWQCYLG RFNDIHVPIR LECVKFASHC LMNHPDLAKD LTEYLKVRSH DPEEAIRHDV IVSIVTAAKK DILLVNDHLL NFVRERTLDK RWRVRKEAMM GLAQIYKKYA LQSAAGKDAA KQIAWIKDKL LHIYYQNSID DRLLVERIFA QYMVPHNLET TERMKCLYYL YATLDLNAVK ALNEMWKCQN LLRHQVKDLL DLIKQPKTDA SVKAIFSKVM VITRNLPDPG KAQDFMKKFT QVLEDDEKIR KQLEVLVSPT CSCKQAEGCV REITKKLGNP KQPTNPFLEM IKFLLERIAP VHIDTESISA LIKQVNKSID GTADDEDEGV PTDQAIRAGL ELLKVLSFTH PISFHSAETF ESLLACLKMD DEKVAEAALQ IFKNTGSKIE EDFPHIRSAL LPVLHHKSKK GPPRQAKYAI HCIHAIFSSK ETQFAQIFEP LHKSLDPSNL EHLITPLVTI GHIALLAPDQ FAAPLKSLVA TFIVKDLLMN DRLPGKKTTK LWVPDEEVSP ETMVKIQAIK MMVRWLLGMK NNHSKSGTST LRLLTTILHS DGDLTEQGKI SKPDMSRLRL AAGSAIVKLA QEPCYHEIIT LEQYQLCALA INDECYQVRQ VFAQKLHKGL SRLRLPLEYM AICALCAKDP VKERRAHARQ CLVKNINVRR EYLKQHAAVS EKLLSLLPEY VVPYTIHLLA HDPDYVKVQD IEQLKDVKEC LWFVLEILMA KNENNSHAFI RKMVENIKQT KDAQGPDDAK MNEKLYTVCD VAMNIIMSKS TTYSLESPKD PVLPARFFTQ PDKNFSNTKN YLPPEMKSFF TPGKPKTTNV LGAVNKPLSS AGKQSQTKSS RMETVSNASS SSNPSSPGRI KGRLDSSEMD HSENEDYTMS SPLPGKKSDK RDDSDLVRSE LEKPRGRKKT PVTEQEEKLG MDDLTKLVQE QKPKGSQRSR KRGHTASESD EQQWPEEKRL KEDILENEDE QNSPPKKGKR GRPPKPLGGG TPKEEPTMKT SKKGSKKKSG PPAPEEEEEE ERQSGNTEQK SKSKQHRVSR RAQQRAESPE SSAIESTQST PQKGRGRPSK TPSPSQPKKN VRVGRSKQAA TKENDSSEEV DVFQGSSPVD DIPQEETEEE EVSTVNVRRR SAKRERR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.