Details for: ZHX3
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 38.86rCSI 53.18%PRS 74.25
-
CSI 28.55rCSI 64.01%PRS 66.58
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CSI 25.83rCSI 55.03%PRS 58.55
-
CSI 24.61rCSI 41.31%PRS 65.68
-
CSI 23.78rCSI 37.93%PRS 74.62
-
CSI 22.47rCSI 40.23%PRS 82
-
CSI 18.9rCSI 33.38%PRS 65.22
-
CSI 18.11rCSI 44.01%PRS 63.62
-
CSI 16.22rCSI 30.38%PRS 71.76
-
CSI 14.88rCSI 46.5%PRS 67.35
-
CSI 12.63rCSI 16.28%PRS 66.84
-
CSI 12.36rCSI 44.49%PRS 63.59
-
CSI 12.19rCSI 29.77%PRS 75.25
-
CSI 11.89rCSI 37.18%PRS 69.62
-
CSI 11.59rCSI 14.41%PRS 63.57
-
CSI 10.97rCSI 41.47%PRS 66.25
-
CSI 10.86rCSI 27.91%PRS 79.3
-
CSI 10.68rCSI 27.62%PRS 78.53
-
CSI 10.12rCSI 11.69%PRS 75.19
-
CSI 9.93rCSI 11.86%PRS 65.74
-
CSI 9.76rCSI 12.53%PRS 73.29
-
CSI 9.29rCSI 21.45%PRS 71.17
-
CSI 9.25rCSI 36.18%PRS 62.01
-
CSI 8.9rCSI 14.31%PRS 67.03
-
CSI 8.78rCSI 23.31%PRS 87.18
-
CSI 8.77rCSI 32.84%PRS 75.76
-
CSI 8.7rCSI 19.86%PRS 74.65
-
CSI 8.56rCSI 50.39%PRS 66.23
-
CSI 8.48rCSI 18.03%PRS 76.93
-
CSI 8.46rCSI 12.9%PRS 79.68
-
CSI 8.05rCSI 19.35%PRS 85.16
-
CSI 7.32rCSI 19.11%PRS 80.79
-
CSI 7.14rCSI 10.24%PRS 73.1
-
CSI 6.65rCSI 11.65%PRS 77.18
-
CSI 6.55rCSI 16.61%PRS 73.78
-
CSI 6.07rCSI 12.32%PRS 61.99
-
CSI 5.95rCSI 15.9%PRS 75.19
-
CSI 5.68rCSI 11.78%PRS 79.8
-
CSI 5.39rCSI 5.01%PRS 83.64
-
CSI 5.28rCSI 11.63%PRS 65.46
-
CSI 5.11rCSI 10.25%PRS 73.93
-
CSI 4.98rCSI 11.01%PRS 69.29
-
CSI 4.9rCSI 36.03%PRS 70.9
-
CSI 4.8rCSI 13.63%PRS 78.47
-
CSI 4.69rCSI 5.14%PRS 84.52
-
CSI 4.61rCSI 3.74%PRS 82.33
-
CSI 4.56rCSI 8.29%PRS 74.62
-
CSI 4.54rCSI 3.36%PRS 76.93
-
CSI 4.4rCSI 22.55%PRS 85.64
-
CSI 4.33rCSI 10.15%PRS 82.17
-
CSI 4.3rCSI 11.84%PRS 78.24
-
CSI 4.23rCSI 12.48%PRS 81.88
-
CSI 4.19rCSI 7.53%PRS 76.48
-
CSI 4.01rCSI 12.85%PRS 80.49
-
CSI 3.99rCSI 10.41%PRS 83.84
-
CSI 3.98rCSI 5.64%PRS 79.75
-
CSI 3.97rCSI 10.58%PRS 70.3
-
CSI 3.95rCSI 16.8%PRS 75.32
-
CSI 3.92rCSI 12.75%PRS 80.31
-
CSI 3.75rCSI 5.98%PRS 86.18
-
CSI 3.7rCSI 31.89%PRS 71.44
-
CSI 3.6rCSI 5.58%PRS 85.89
-
CSI 3.49rCSI 6.04%PRS 74.98
-
CSI 3.48rCSI 13.52%PRS 81.65
-
CSI 3.46rCSI 8.24%PRS 82.6
-
CSI 3.42rCSI 13.81%PRS 82.91
-
CSI 3.34rCSI 19.26%PRS 79.21
-
CSI 3.21rCSI 7.35%PRS 83.6
-
CSI 3.17rCSI 8.38%PRS 88.66
-
CSI 3.12rCSI 7.44%PRS 86.29
-
CSI 3.06rCSI 6.29%PRS 70.24
-
CSI 2.98rCSI 21.29%PRS 80.25
-
CSI 2.97rCSI 4.87%PRS 72.87
-
CSI 2.92rCSI 16.52%PRS 69.15
-
CSI 2.9rCSI 6.28%PRS 70.38
-
CSI 2.79rCSI 6.91%PRS 82.91
-
CSI 2.79rCSI 9.16%PRS 68.99
-
CSI 2.72rCSI 13.01%PRS 82.79
-
CSI 2.67rCSI 27.59%PRS 76.4
-
CSI 2.66rCSI 4.09%PRS 71.87
-
CSI 2.66rCSI 3.91%PRS 76.04
-
CSI 2.55rCSI 2.19%PRS 88.31
-
CSI 2.47rCSI 11.85%PRS 79.01
-
CSI 2.28rCSI 4.03%PRS 87.4
-
CSI 2.25rCSI 53.97%PRS 63.67
-
CSI 2.25rCSI 3.06%PRS 90.26
-
CSI 2.23rCSI 53.79%PRS 64.26
-
CSI 2.04rCSI 5.3%PRS 82.83
-
CSI 2.02rCSI 17.48%PRS 76.96
-
CSI 2.01rCSI 11.01%PRS 79.45
-
CSI 1.97rCSI 13.94%PRS 75.87
-
CSI 1.96rCSI 8.71%PRS 83.37
-
CSI 1.94rCSI 6.51%PRS 67.02
-
CSI 1.92rCSI 5.91%PRS 86.52
-
CSI 1.91rCSI 1.99%PRS 80.4
-
CSI 1.89rCSI 3.75%PRS 78.67
-
CSI 1.68rCSI 1.76%PRS 85.75
-
CSI 1.63rCSI 14.38%PRS 71
-
CSI 1.61rCSI 1.99%PRS 81.03
-
CSI 1.57rCSI 8.68%PRS 90.64
-
CSI 0.4rCSI 6.0%PRS 74.3%
-
CSI 0.6rCSI 3.7%PRS 75.0%
-
CSI 0.7rCSI 3.4%PRS 77.3%
-
CSI 0.7rCSI 2.8%PRS 88.8%
-
CSI 0.8rCSI 4.2%PRS 83.8%
-
CSI 0.9rCSI 2.4%PRS 88.7%
-
CSI 1.0rCSI 2.9%PRS 72.6%
-
CSI 1.1rCSI 4.9%PRS 71.4%
-
CSI 1.1rCSI 5.0%PRS 67.1%
-
CSI 1.2rCSI 4.4%PRS 74.2%
-
CSI 1.3rCSI 5.2%PRS 77.6%
-
CSI 1.3rCSI 4.3%PRS 79.6%
-
CSI 1.4rCSI 3.3%PRS 69.9%
-
CSI 1.4rCSI 9.4%PRS 77.4%
-
CSI 1.5rCSI 3.2%PRS 82.2%
-
CSI 1.5rCSI 5.1%PRS 69.0%
-
CSI 1.5rCSI 2.4%PRS 84.2%
-
CSI 1.5rCSI 16.0%PRS 78.8%
-
CSI 1.6rCSI 8.7%PRS 90.6%
-
CSI 1.6rCSI 2.0%PRS 81.0%
-
CSI 1.6rCSI 14.4%PRS 71.0%
-
CSI 1.7rCSI 1.8%PRS 85.8%
-
CSI 1.9rCSI 3.8%PRS 78.7%
-
CSI 1.9rCSI 2.0%PRS 80.4%
-
CSI 1.9rCSI 5.9%PRS 86.5%
-
CSI 1.9rCSI 6.5%PRS 67.0%
-
CSI 2.0rCSI 8.7%PRS 83.4%
-
CSI 2.0rCSI 13.9%PRS 75.9%
-
CSI 2.0rCSI 11.0%PRS 79.5%
-
CSI 2.0rCSI 17.5%PRS 77.0%
-
CSI 2.0rCSI 5.3%PRS 82.8%
-
CSI 2.2rCSI 53.8%PRS 64.3%
-
CSI 2.3rCSI 3.1%PRS 90.3%
-
CSI 2.3rCSI 54.0%PRS 63.7%
-
CSI 2.3rCSI 4.0%PRS 87.4%
-
CSI 2.5rCSI 11.9%PRS 79.0%
-
CSI 2.6rCSI 2.2%PRS 88.3%
-
CSI 2.7rCSI 3.9%PRS 76.0%
-
CSI 2.7rCSI 4.1%PRS 71.9%
-
CSI 2.7rCSI 27.6%PRS 76.4%
-
CSI 2.7rCSI 13.0%PRS 82.8%
-
CSI 2.8rCSI 9.2%PRS 69.0%
-
CSI 2.8rCSI 6.9%PRS 82.9%
-
CSI 2.9rCSI 6.3%PRS 70.4%
-
CSI 2.9rCSI 16.5%PRS 69.2%
-
CSI 3.0rCSI 4.9%PRS 72.9%
-
CSI 3.0rCSI 21.3%PRS 80.3%
-
CSI 3.1rCSI 6.3%PRS 70.2%
-
CSI 3.1rCSI 7.4%PRS 86.3%
-
CSI 3.2rCSI 8.4%PRS 88.7%
-
CSI 3.2rCSI 7.4%PRS 83.6%
-
CSI 3.3rCSI 19.3%PRS 79.2%
-
CSI 3.4rCSI 13.8%PRS 82.9%
-
CSI 3.5rCSI 8.2%PRS 82.6%
-
CSI 3.5rCSI 13.5%PRS 81.7%
-
CSI 3.5rCSI 6.0%PRS 75.0%
-
CSI 3.6rCSI 5.6%PRS 85.9%
-
CSI 3.7rCSI 31.9%PRS 71.4%
-
CSI 3.8rCSI 6.0%PRS 86.2%
-
CSI 3.9rCSI 12.8%PRS 80.3%
-
CSI 4.0rCSI 16.8%PRS 75.3%
-
CSI 4.0rCSI 10.6%PRS 70.3%
-
CSI 4.0rCSI 5.6%PRS 79.8%
-
CSI 4.0rCSI 10.4%PRS 83.8%
-
CSI 4.0rCSI 12.9%PRS 80.5%
-
CSI 4.2rCSI 7.5%PRS 76.5%
-
CSI 4.2rCSI 12.5%PRS 81.9%
-
CSI 4.3rCSI 11.8%PRS 78.2%
-
CSI 4.3rCSI 10.2%PRS 82.2%
-
CSI 4.4rCSI 22.6%PRS 85.6%
-
CSI 4.5rCSI 3.4%PRS 76.9%
-
CSI 4.6rCSI 8.3%PRS 74.6%
-
CSI 4.6rCSI 3.7%PRS 82.3%
-
CSI 4.7rCSI 5.1%PRS 84.5%
-
CSI 4.8rCSI 13.6%PRS 78.5%
-
CSI 4.9rCSI 36.0%PRS 70.9%
-
CSI 5.0rCSI 11.0%PRS 69.3%
-
CSI 5.1rCSI 10.3%PRS 73.9%
-
CSI 5.3rCSI 11.6%PRS 65.5%
-
CSI 5.4rCSI 5.0%PRS 83.6%
-
CSI 5.7rCSI 11.8%PRS 79.8%
-
CSI 6.0rCSI 15.9%PRS 75.2%
-
CSI 6.1rCSI 12.3%PRS 62.0%
-
CSI 6.6rCSI 16.6%PRS 73.8%
-
CSI 6.7rCSI 11.7%PRS 77.2%
-
CSI 7.1rCSI 10.2%PRS 73.1%
-
CSI 7.3rCSI 19.1%PRS 80.8%
-
CSI 8.1rCSI 19.4%PRS 85.2%
-
CSI 8.5rCSI 12.9%PRS 79.7%
-
CSI 8.5rCSI 18.0%PRS 76.9%
-
CSI 8.6rCSI 50.4%PRS 66.2%
-
CSI 8.7rCSI 19.9%PRS 74.7%
-
CSI 8.8rCSI 32.8%PRS 75.8%
-
CSI 8.8rCSI 23.3%PRS 87.2%
-
CSI 8.9rCSI 14.3%PRS 67.0%
-
CSI 9.3rCSI 36.2%PRS 62.0%
-
CSI 9.3rCSI 21.5%PRS 71.2%
-
CSI 9.8rCSI 12.5%PRS 73.3%
-
CSI 9.9rCSI 11.9%PRS 65.7%
-
CSI 10.1rCSI 11.7%PRS 75.2%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 3673529618
Symbol: ZHX3_HUMAN
Name: Zinc fingers and homeoboxes protein 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12659632
Title: Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3.
PubMed ID: 12659632
DOI: 10.1042/bj20021866
PubMed ID: 9455477
Title: Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9455477
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14659886
Title: The mouse zinc-fingers and homeoboxes (ZHX) family: ZHX2 forms a heterodimer with ZHX3.
PubMed ID: 14659886
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21174497
Title: Impact of zinc fingers and homeoboxes 3 on the regulation of mesenchymal stem cell osteogenic differentiation.
PubMed ID: 21174497
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 956
- Mass: 104658
- Checksum: B3DB35CFC1781A3A
- Sequence:
MASKRKSTTP CMIPVKTVVL QDASMEAQPA ETLPEGPQQD LPPEASAASS EAAQNPSSTD GSTLANGHRS TLDGYLYSCK YCDFRSHDMT QFVGHMNSEH TDFNKDPTFV CSGCSFLAKT PEGLSLHNAT CHSGEASFVW NVAKPDNHVV VEQSIPESTS TPDLAGEPSA EGADGQAEII ITKTPIMKIM KGKAEAKKIH TLKENVPSQP VGEALPKLST GEMEVREGDH SFINGAVPVS QASASSAKNP HAANGPLIGT VPVLPAGIAQ FLSLQQQPPV HAQHHVHQPL PTAKALPKVM IPLSSIPTYN AAMDSNSFLK NSFHKFPYPT KAELCYLTVV TKYPEEQLKI WFTAQRLKQG ISWSPEEIED ARKKMFNTVI QSVPQPTITV LNTPLVASAG NVQHLIQAAL PGHVVGQPEG TGGGLLVTQP LMANGLQATS SPLPLTVTSV PKQPGVAPIN TVCSNTTSAV KVVNAAQSLL TACPSITSQA FLDASIYKNK KSHEQLSALK GSFCRNQFPG QSEVEHLTKV TGLSTREVRK WFSDRRYHCR NLKGSRAMIP GDHSSIIIDS VPEVSFSPSS KVPEVTCIPT TATLATHPSA KRQSWHQTPD FTPTKYKERA PEQLRALESS FAQNPLPLDE ELDRLRSETK MTRREIDSWF SERRKKVNAE ETKKAEENAS QEEEEAAEDE GGEEDLASEL RVSGENGSLE MPSSHILAER KVSPIKINLK NLRVTEANGR NEIPGLGACD PEDDESNKLA EQLPGKVSCK KTAQQRHLLR QLFVQTQWPS NQDYDSIMAQ TGLPRPEVVR WFGDSRYALK NGQLKWYEDY KRGNFPPGLL VIAPGNRELL QDYYMTHKML YEEDLQNLCD KTQMSSQQVK QWFAEKMGEE TRAVADTGSE DQGPGTGELT AVHKGMGDTY SEVSENSESW EPRVPEASSE PFDTSSPQAG RQLETD