Details for: ZSWIM8
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.26
Marker Score: 77,478 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.25
Marker Score: 11,892 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.25
Marker Score: 26,682 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.24
Marker Score: 1,911 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.24
Marker Score: 10,614 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.11
Marker Score: 10,442 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.09
Marker Score: 11,273 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.07
Marker Score: 624 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.05
Marker Score: 38,653 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1
Marker Score: 3,873 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1
Marker Score: 1,105 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,721 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,945 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.99
Marker Score: 37,746 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.99
Marker Score: 416 - Cell Name: neuron (CL0000540)
Fold Change: 0.99
Marker Score: 4,035 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,396 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,399 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.94
Marker Score: 546 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 478 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.92
Marker Score: 8,085 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 434 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.91
Marker Score: 2,006 - Cell Name: interneuron (CL0000099)
Fold Change: 0.91
Marker Score: 416 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,709 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.9
Marker Score: 17,977 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.9
Marker Score: 3,773 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.89
Marker Score: 13,365 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.89
Marker Score: 6,846 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.89
Marker Score: 597 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.87
Marker Score: 13,549 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.84
Marker Score: 885 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.84
Marker Score: 964 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.83
Marker Score: 3,461 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.83
Marker Score: 1,902 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.83
Marker Score: 722 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.82
Marker Score: 225 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.81
Marker Score: 536 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.8
Marker Score: 394 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.8
Marker Score: 5,115 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.79
Marker Score: 1,866 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.79
Marker Score: 231 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.78
Marker Score: 3,370 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,262 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.77
Marker Score: 244 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.76
Marker Score: 1,125 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 305 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 581 - Cell Name: fat cell (CL0000136)
Fold Change: 0.76
Marker Score: 423 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.75
Marker Score: 1,013 - Cell Name: germ cell (CL0000586)
Fold Change: 0.74
Marker Score: 1,295 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.73
Marker Score: 355 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.73
Marker Score: 3,926 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.73
Marker Score: 3,061 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.72
Marker Score: 603 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 373 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.72
Marker Score: 871 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.71
Marker Score: 1,375 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.71
Marker Score: 737 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.71
Marker Score: 852 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.7
Marker Score: 222 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.69
Marker Score: 1,164 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.69
Marker Score: 747 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.69
Marker Score: 469 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.68
Marker Score: 3,165 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.68
Marker Score: 735 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.68
Marker Score: 212 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.67
Marker Score: 4,001 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.67
Marker Score: 1,595 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 607 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 0.66
Marker Score: 328 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.66
Marker Score: 308 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.66
Marker Score: 666 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.65
Marker Score: 323 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.64
Marker Score: 147 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.64
Marker Score: 606 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.63
Marker Score: 1,701 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.63
Marker Score: 161 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.63
Marker Score: 21,432 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.62
Marker Score: 665 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.62
Marker Score: 370 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.62
Marker Score: 745 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.62
Marker Score: 2,190 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.62
Marker Score: 230 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.61
Marker Score: 357 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.61
Marker Score: 10,858 - Cell Name: podocyte (CL0000653)
Fold Change: 0.61
Marker Score: 226 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.61
Marker Score: 759 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.61
Marker Score: 558 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.6
Marker Score: 348 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.59
Marker Score: 1,053 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.59
Marker Score: 191 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.59
Marker Score: 390 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.58
Marker Score: 618 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.58
Marker Score: 397 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.58
Marker Score: 4,966
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2579266867
Symbol: ZSWM8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24012004
Title: The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons.
PubMed ID: 24012004
PubMed ID: 33184234
Title: A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming.
PubMed ID: 33184234
PubMed ID: 33184237
Title: The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation.
PubMed ID: 33184237
Sequence Information:
- Length: 1837
- Mass: 197297
- Checksum: 391CF6AE25E4F8C6
- Sequence:
MELMFAEWED GERFSFEDSD RFEEDSLCSF ISEAESLCQN WRGWRKQSAG PNSPTGGGGG GGSGGTRMRD GLVIPLVELS AKQVAFHIPF EVVEKVYPPV PEQLQLRIAF WSFPENEEDI RLYSCLANGS ADEFQRGDQL FRMRAVKDPL QIGFHLSATV VPPQMVPPKG AYNVAVMFDR CRVTSCSCTC GAGAKWCTHV VALCLFRIHN ASAVCLRAPV SESLSRLQRD QLQKFAQYLI SELPQQILPT AQRLLDELLS SQSTAINTVC GAPDPTAGPS ASDQSTWYLD ESTLTDNIKK TLHKFCGPSP VVFSDVNSMY LSSTEPPAAA EWACLLRPLR GREPEGVWNL LSIVREMFKR RDSNAAPLLE ILTDQCLTYE QITGWWYSVR TSASHSSASG HTGRSNGQSE VAAHACASMC DEMVTLWRLA VLDPALSPQR RRELCTQLRQ WQLKVIENVK RGQHKKTLER LFPGFRPAVE ACYFNWEEAY PLPGVTYSGT DRKLALCWAR ALPSRPGASR SGGLEESRDR PRPLPTEPAV RPKEPGTKRK GLGEGVPSSQ RGPRRLSAEG GDKALHKMGP GGGKAKALGG AGSGSKGSAG GGSKRRLSSE DSSLEPDLAE MSLDDSSLAL GAEASTFGGF PESPPPCPLH GGSRGPSTFL PEPPDTYEED GGVYFSEGPE PPTASVGPPG LLPGDVCTQD DLPSTDESGN GLPKTKEAAP AVGEEDDDYQ AYYLNAQDGA GGEEEKAEGG AGEEHDLFAG LKPLEQESRM EVLFACAEAL HAHGYSSEAS RLTVELAQDL LANPPDLKVE PPPAKGKKNK VSTSRQTWVA TNTLSKAAFL LTVLSERPEH HNLAFRVGMF ALELQRPPAS TKALEVKLAY QESEVAALLK KIPLGPSEMS TMRCRAEELR EGTLCDYRPV LPLMLASFIF DVLCAPGSRP PSRNWNSETP GDEELGFEAA VAALGMKTTV SEAEHPLLCE GTRREKGDLA LALMITYKDD QAKLKKILDK LLDRESQTHK PQTLSSFYSS SRPTTASQRS PSKHGGPSAP GALQPLTSGS AGPAQPGSVA GAGPGPTEGF TEKNVPESSP HSPCEGLPSE AALTPRPEGK VPSRLALGSR GGYNGRGWGS PGRPKKKHTG MASIDSSAPE TTSDSSPTLS RRPLRGGWAP TSWGRGQDSD SISSSSSDSL GSSSSSGSRR ASASGGARAK TVEVGRYKGR RPESHAPHVP NQPSEAAAHF YFELAKTVLI KAGGNSSTSI FTHPSSSGGH QGPHRNLHLC AFEIGLYALG LHNFVSPNWL SRTYSSHVSW ITGQAMEIGS AALTILVECW DGHLTPPEVA SLADRASRAR DSNMVRAAAE LALSCLPHAH ALNPNEIQRA LVQCKEQDNL MLEKACMAVE EAAKGGGVYP EVLFEVAHQW FWLYEQTAGG SSTAREGATS CSASGIRAGG EAGRGMPEGR GGPGTEPVTV AAAAVTAAAT VVPVISVGSS LYPGPGLGHG HSPGLHPYTA LQPHLPCSPQ YLTHPAHPAH PMPHMPRPAV FPVPSSAYPQ GVHPAFLGAQ YPYSVTPPSL AATAVSFPVP SMAPITVHPY HTEPGLPLPT SVACELWGQG TVSSVHPAST FPAIQGASLP ALTTQPSPLV SGGFPPPEEE THSQPVNPHS LHHLHAAYRV GMLALEMLGR RAHNDHPNNF SRSPPYTDDV KWLLGLAAKL GVNYVHQFCV GAAKGVLSPF VLQEIVMETL QRLSPAHAHN HLRAPAFHQL VQRCQQAYMQ YIHHRLIHLT PADYDDFVNA IRSARSAFCL TPMGMMQFND ILQNLKRSKQ TKELWQRVSL EMATFSP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.