Details for: NCOA6

Gene ID: 23054

Symbol: NCOA6

Ensembl ID: ENSG00000198646

Description: nuclear receptor coactivator 6

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.04
    Marker Score: 2,252
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.94
    Marker Score: 65,498
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.91
    Marker Score: 40,852
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.87
    Marker Score: 4,098
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.86
    Marker Score: 27,770
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.84
    Marker Score: 69,969
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.83
    Marker Score: 7,446
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.8
    Marker Score: 13,801
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.77
    Marker Score: 16,655
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.76
    Marker Score: 65,053
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.73
    Marker Score: 6,703
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.73
    Marker Score: 1,990
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.71
    Marker Score: 7,086
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7
    Marker Score: 104,626
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.68
    Marker Score: 33,434
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.67
    Marker Score: 37,345
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.65
    Marker Score: 17,065
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.65
    Marker Score: 15,642
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.64
    Marker Score: 862
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.62
    Marker Score: 13,909
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.62
    Marker Score: 2,828
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.61
    Marker Score: 942
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.57
    Marker Score: 916
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.56
    Marker Score: 3,001
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.47
    Marker Score: 3,465
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.46
    Marker Score: 2,251
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.45
    Marker Score: 1,806
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.45
    Marker Score: 5,145
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.42
    Marker Score: 594
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.4
    Marker Score: 3,357
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.39
    Marker Score: 832
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.39
    Marker Score: 5,831
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.39
    Marker Score: 688
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.39
    Marker Score: 1,070
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.34
    Marker Score: 1,515
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.3
    Marker Score: 725
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.29
    Marker Score: 373
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.28
    Marker Score: 1,379
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.27
    Marker Score: 372
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.26
    Marker Score: 19,745
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.26
    Marker Score: 6,751
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.25
    Marker Score: 393
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.24
    Marker Score: 6,525
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.24
    Marker Score: 697
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.23
    Marker Score: 712
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.22
    Marker Score: 387
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.21
    Marker Score: 331
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.2
    Marker Score: 3,008
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.2
    Marker Score: 379
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.18
    Marker Score: 1,021
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.18
    Marker Score: 5,467
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.17
    Marker Score: 1,580
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.17
    Marker Score: 1,421
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.17
    Marker Score: 957
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.16
    Marker Score: 20,655
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.14
    Marker Score: 1,091
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.14
    Marker Score: 8,611
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.13
    Marker Score: 435
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 1.12
    Marker Score: 3,772
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.12
    Marker Score: 760
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.11
    Marker Score: 2,546
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.1
    Marker Score: 354
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.05
    Marker Score: 1,300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.05
    Marker Score: 6,751
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.05
    Marker Score: 509
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.02
    Marker Score: 706
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.01
    Marker Score: 1,219
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1
    Marker Score: 4,175
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1
    Marker Score: 867
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1
    Marker Score: 1,070
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,709
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,935
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.99
    Marker Score: 490
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.98
    Marker Score: 1,392
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.98
    Marker Score: 367
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,391
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.98
    Marker Score: 471
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.98
    Marker Score: 15,723
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.97
    Marker Score: 728
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.97
    Marker Score: 2,754
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.96
    Marker Score: 1,013
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.95
    Marker Score: 4,116
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.95
    Marker Score: 513
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 0.94
    Marker Score: 493
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,398
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.94
    Marker Score: 239
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 482
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.93
    Marker Score: 343
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 437
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.91
    Marker Score: 1,525
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.91
    Marker Score: 1,472
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,706
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.9
    Marker Score: 1,832
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.9
    Marker Score: 599
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.88
    Marker Score: 232
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.88
    Marker Score: 777
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,295
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.87
    Marker Score: 574
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 310
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.85
    Marker Score: 322

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NCOA6 is a member of the nuclear receptor coactivator family, which is known to enhance the transcriptional activity of nuclear receptors. The NCOA6 protein contains multiple functional domains, including a histone-modifying complex, a transcriptional activator, and a coactivator activity. This gene is highly conserved across species, with high sequence identity between human and mouse NCOA6 proteins. NCOA6 is also involved in the regulation of circadian gene expression, with interactions with clock proteins such as Bmal1 and npas2. **Pathways and Functions** NCOA6 is involved in various cellular pathways, including: 1. **Transcriptional regulation**: NCOA6 enhances the transcriptional activity of nuclear receptors, such as estrogen, thyroid hormone, and retinoid X receptors, by interacting with these receptors and recruiting coactivators. 2. **Circadian rhythm maintenance**: NCOA6 interacts with clock proteins such as Bmal1 and npas2 to regulate circadian gene expression. 3. **Metabolism**: NCOA6 is involved in the regulation of cholesterol and lipid metabolism, with interactions with transcription factors such as PPARα and SREBP. 4. **Cellular responses to stimuli**: NCOA6 is involved in the regulation of cellular responses to stress, including DNA damage response and cytoprotection. 5. **Developmental biology**: NCOA6 is involved in the regulation of developmental processes, including heart development and neuronal differentiation. **Clinical Significance** Dysregulation of NCOA6 has been implicated in various diseases, including: 1. **Cancer**: NCOA6 has been shown to be overexpressed in several types of cancer, including breast, lung, and colon cancer. 2. **Neurodegenerative diseases**: NCOA6 has been implicated in the regulation of circadian gene expression, which is disrupted in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. 3. **Metabolic disorders**: NCOA6 has been shown to be involved in the regulation of lipid metabolism, which is disrupted in metabolic disorders such as obesity and type 2 diabetes. 4. **Cardiovascular disease**: NCOA6 has been implicated in the regulation of cholesterol metabolism, which is disrupted in cardiovascular disease. In conclusion, NCOA6 is a critical gene involved in various cellular processes, including transcriptional regulation, circadian rhythm maintenance, and metabolism. Dysregulation of NCOA6 has been implicated in various diseases, highlighting the importance of this gene in maintaining cellular homeostasis.

Genular Protein ID: 4197321814

Symbol: NCOA6_HUMAN

Name: Nuclear receptor coactivator 6

UniProtKB Accession Codes:

Q14686 A6NLF1 B2RMN5 E1P5P7 Q9NTZ9 Q9UH74 Q9UK86

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 22 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 12 RefSeq 3 SAM 1 SIGNOR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10567404

Title: A nuclear factor ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

PubMed ID: 10567404

DOI: 10.1074/jbc.274.48.34283

PubMed ID: 10866662

Title: A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP.

PubMed ID: 10866662

DOI: 10.1128/mcb.20.14.5048-5063.2000

PubMed ID: 10681503

Title: Cloning and characterization of RAP250, a nuclear receptor coactivator.

PubMed ID: 10681503

DOI: 10.1074/jbc.275.8.5308

PubMed ID: 10823961

Title: Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator.

PubMed ID: 10823961

DOI: 10.1073/pnas.97.11.6212

PubMed ID: 8724849

Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8724849

DOI: 10.1093/dnares/3.1.17

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11517327

Title: Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function.

PubMed ID: 11517327

DOI: 10.1073/pnas.181347498

PubMed ID: 11443112

Title: Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM).

PubMed ID: 11443112

DOI: 10.1074/jbc.m101517200

PubMed ID: 12039952

Title: Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.

PubMed ID: 12039952

DOI: 10.1074/jbc.m201053200

PubMed ID: 12215545

Title: NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC.

PubMed ID: 12215545

DOI: 10.1128/mcb.22.19.6883-6894.2002

PubMed ID: 12482968

Title: Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

PubMed ID: 12482968

DOI: 10.1128/mcb.23.1.140-149.2003

PubMed ID: 11773444

Title: Ser-884 adjacent to the LXXLL motif of coactivator TRBP defines selectivity for ERs and TRs.

PubMed ID: 11773444

DOI: 10.1210/mend.16.1.0755

PubMed ID: 17021013

Title: Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

PubMed ID: 17021013

DOI: 10.1073/pnas.0607313103

PubMed ID: 17500065

Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

PubMed ID: 17500065

DOI: 10.1074/jbc.m701574200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 2063
  • Mass: 219145
  • Checksum: 73219502F5138427
  • Sequence:
    • MVLDDLPNLE DIYTSLCSST MEDSEMDFDS GLEDDDTKSD SILEDSTIFV AFKGNIDDKD 
FKWKLDAILK NVPNLLHMES SKLKVQKVEP WNSVRVTFNI PREAAERLRI LAQSNNQQLR 
DLGILSVQIE GEGAINLALA QNRSQDVRMN GPMGAGNSVR MEAGFPMASG PGIIRMNNPA 
TVMIPPGGNV SSSMMAPGPN PELQPRTPRP ASQSDAMDPL LSGLHIQQQS HPSGSLAPPH 
HPMQPVSVNR QMNPANFPQL QQQQQQQQQQ QQQQQQQQQQ QQQQQLQARP PQQHQQQQPQ 
GIRPQFTAPT QVPVPPGWNQ LPSGALQPPP AQGSLGTMTA NQGWKKAPLP GPMQQQLQAR 
PSLATVQTPS HPPPPYPFGS QQASQAHTNF PQMSNPGQFT APQMKSLQGG PSRVPTPLQQ 
PHLTNKSPAS SPSSFQQGSP ASSPTVNQTQ QQMGPRPPQN NPLPQGFQQP VSSPGRNPMV 
QQGNVPPNFM VMQQQPPNQG PQSLHPGLGG MPKRLPPGFS AGQANPNFMQ GQVPSTTATT 
PGNSGAPQLQ ANQNVQHAGG QGAGPPQNQM QVSHGPPNMM QPSLMGIHGN MNNQQAGTSG 
VPQVNLSNMQ GQPQQGPPSQ LMGMHQQIVP SQGQMVQQQG TLNPQNPMIL SRAQLMPQGQ 
MMVNPPSQNL GPSPQRMTPP KQMLSQQGPQ MMAPHNQMMG PQGQVLLQQN PMIEQIMTNQ 
MQGNKQQFNT QNQSNVMPGP AQIMRGPTPN MQGNMVQFTG QMSGQMLPQQ GPVNNSPSQV 
MGIQGQVLRP PGPSPHMAQQ HGDPATTANN DVSLSQMMPD VSIQQTNMVP PHVQAMQGNS 
ASGNHFSGHG MSFNAPFSGA PNGNQMSCGQ NPGFPVNKDV TLTSPLLVNL LQSDISAGHF 
GVNNKQNNTN ANKPKKKKPP RKKKNSQQDL NTPDTRPAGL EEADQPPLPG EQGINLDNSG 
PKLPEFSNRP PGYPSQPVEQ RPLQQMPPQL MQHVAPPPQP PQQQPQPQLP QQQQPPPPSQ 
PQSQQQQQQQ QQMMMMLMMQ QDPKSVRLPV SQNVHPPRGP LNPDSQRMPM QQSGSVPVMV 
SLQGPASVPP SPDKQRMPMP VNTPLGSNSR KMVYQESPQN PSSSPLAEMA SLPEASGSEA 
PSVPGGPNNM PSHVVLPQNQ LMMTGPKPGP SPLSATQGAT PQQPPVNSLP SSHGHHFPNV 
AAPTQTSRPK TPNRASPRPY YPQTPNNRPP STEPSEISLS PERLNASIAG LFPPQINIPL 
PPRPNLNRGF DQQGLNPTTL KAIGQAPSNL TMNPSNFATP QTHKLDSVVV NSGKQSNSGA 
TKRASPSNSR RSSPGSSRKT TPSPGRQNSK APKLTLASQT NAALLQNVEL PRNVLVSPTP 
LANPPVPGSF PNNSGLNPQN STVSVAAVGG VVEDNKESLN VPQDSDCQNS QSRKEQVNIE 
LKAVPAQEVK MVVPEDQSKK DGQPSDPNKL PSVEENKNLV SPAMREAPTS LSQLLDNSGA 
PNVTIKPPGL TDLEVTPPVV SGEDLKKASV IPTLQDLSSS KEPSNSLNLP HSNELCSSLV 
HPELSEVSSN VAPSIPPVMS RPVSSSSIST PLPPNQITVF VTSNPITTSA NTSAALPTHL 
QSALMSTVVT MPNAGSKVMV SEGQSAAQSN ARPQFITPVF INSSSIIQVM KGSQPSTIPA 
APLTTNSGLM PPSVAVVGPL HIPQNIKFSS APVPPNALSS SPAPNIQTGR PLVLSSRATP 
VQLPSPPCTS SPVVPSHPPV QQVKELNPDE ASPQVNTSAD QNTLPSSQST TMVSPLLTNS 
PGSSGNRRSP VSSSKGKGKV DKIGQILLTK ACKKVTGSLE KGEEQYGADG ETEGQGLDTT 
APGLMGTEQL STELDSKTPT PPAPTLLKMT SSPVGPGTAS AGPSLPGGAL PTSVRSIVTT 
LVPSELISAV PTTKSNHGGI ASESLAGGLV EEKVGSHPEL LPSIAPSQNL VSKETSTTAL 
QASVARPELE VNAAIVSGQS SEPKEIVEKS KIPGRRNSRT EEPTVASESV ENGHRKRSSR 
PASASSSTKD ITSAVQSKRR KSK

Genular Protein ID: 2029777422

Symbol: F6M2K2_HUMAN

Name: N/A

UniProtKB Accession Codes:

F6M2K2

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 2 GO 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 2 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 2 Proteomes 2 RefSeq 2 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 21552418

Title: Identification and characterization of the alternatively spliced nuclear receptor coactivator-6 isoforms.

PubMed ID: 21552418

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

Sequence Information:

  • Length: 1070
  • Mass: 115339
  • Checksum: 2FE1C6297C26DEE6
  • Sequence:
    • MVLDDLPNLE DIYTSLCSST MEDSEMDFDS GLEDDDTKSD SILEDSTIFV AFKGNIDDKD 
FKWKLDAILK NVPNLLHMES SKLKVQKVEP WNSVRVTFNI PREAAERLRI LAQSNNQQLR 
DLGILSVQIE GEGAINLALA QNRSQDVRMN GPMGAGNSVR MEAGFPMASG PGIIRMNNPA 
TVMIPPGGNV SSSMMAPGPN PELQPRTPRP ASQSDAMDPL LSGLHIQQQS HPSGSLAPPH 
HPMQPVSVNR QMNPANFPQL QQQQQQQQQQ QQQQQQQQQQ QQQQQLQARP PQQHQQQQPQ 
GIRPQFTAPT QVPVPPGWNQ LPSGALQPPP AQGSLGTMTA NQGWKKAPLP GPMQQQLQAR 
PSLATVQTPS HPPPPYPFGS QQASQAHTNF PQMSNPGQFT APQMKSLQGG PSRVPTPLQQ 
PHLTNKSPAS SPSSFQQGSP ASSPTVNQTQ QQMGPRPPQN NPLPQGFQQP VSSPGRNPMV 
QQGNVPPNFM VMQQQPPNQG PQSLHPGLGG MPKRLPPGFS AGQANPNFMQ GQVPSTTATT 
PGNSGAPQLQ ANQNVQHAGG QGAGPPQNQM QVSHGPPNMM QPSLMGIHGN MNNQQAGTSG 
VPQVNLSNMQ GQPQQGPPSQ LMGMHQQIVP SQGQMVQQQG TLNPQNPMIL SRAQLMPQGQ 
MMVNPPSQNL GPSPQRMTPP KQMLSQQGPQ MMAPHNQMMG PQGQVLLQQN PMIEQIMTNQ 
MQGNKQQFNT QNQSNVMPGP AQIMRGPTPN MQGNMVQFTG QMSGQMLPQQ GPVNNSPSQV 
MGIQGQVLRP PGPSPHMAQQ HGDPATTANN DVSLSQMMPD VSIQQTNMVP PHVQAMQGNS 
ASGNHFSGHG MSFNAPFSGA PNGNQMSCGQ NPGFPVNKDV TLTSPLLVNL LQSDISAGHF 
GVNNKQNNTN ANKPKKKKPP RKKKNSQQDL NTPDTRPAGL EEADQPPLPG EQGINLDNSG 
PKLPEFSNRP PAPSQNLVSK ETSTTALQAS VARPELEVNA AIVSGQSSEP KEIVEKSKIP 
GRRNSRTEEP TVASESVENG HRKRSSRPAS ASSSTKDITS AVQSKRRKSK

Genular Protein ID: 3037383671

Symbol: F6M2K3_HUMAN

Name: N/A

UniProtKB Accession Codes:

F6M2K3

Database IDs:

BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1

Citations:

PubMed ID: 21552418

Title: Identification and characterization of the alternatively spliced nuclear receptor coactivator-6 isoforms.

PubMed ID: 21552418

Sequence Information:

  • Length: 1975
  • Mass: 209888
  • Checksum: 33853925B984CEAA
  • Sequence:
    • MVLDDLPNLE DIYTSLCSST MEDSEMDFDS GLEDDDTKSD SILEDSTIFV AFKGNIDDKD 
FKWKLDAILK NVPNLLHMES SKLKVQKVEP WNSVRVTFNI PREAAERLRI LAQSNNQQLR 
DLGILSVQIE GEGAINLALA QNRSQDVRMN GPMGAGNSVR MEAGFPMASG PGIIRMNNPA 
TVMIPPGGNV SSSMMAPGPN PELQPRTPRP ASQSDAMDPL LSGLHIQQQS HPSGSLAPPH 
HPMQPVSVNR QMNPANFPQL QQQQQQQQQQ QQQQQQQQQQ QQQQQLQARP PQQHQQQQPQ 
GIRPQFTAPT QVPVPPGWNQ LPSGALQPPP AQGSLGTMTA NQGWKKAPLP GPMQQQLQAR 
PSLATVQTPS HPPPPYPFGS QQASQAHTNF PQMSNPGQFT APQMKSLQGG PSRVPTPLQQ 
PHLTNKSPAS SPSSFQQGSP ASSPTVNQTQ QQMGPRPPQN NPLPQGFQQP VSSPGRNPMV 
QQGNVPPNFM VMQQQPPNQG PQSLHPGLGG MPKRLPPGFS AGQANPNFMQ GQVPSTTATT 
PGNSGAPQLQ ANQNVQHAGG QGAGPPQNQM QVSHGPPNMM QPSLMGIHGN MNNQQAGTSG 
VPQVNLSNMQ GQPQQGPPSQ LMGMHQQIVP SQGQMVQQQG TLNPQNPMIL SRAQLMPQGQ 
MMVNPPSQNL GPSPQRMTPP KQMLSQQGPQ MMAPHNQMMG PQGQVLLQQN PMIEQIMTNQ 
MQGNKQQFNT QNQSNVMPGP AQIMRGPTPN MQGNMVQFTG QMSGQMLPQQ GPVNNSPSQV 
MGIQGQVLRP PGPSPHMAQQ HGDPATTANN DVSLSQMMPD VSIQQTNMVP PHVQAMQGNS 
ASGNHFSGHG MSFNAPFSGA PNGNQMSCGQ NPGFPVNKDV TLTSPLLVNL LQSDISAGHF 
GVNNKQNNTN ANKPKKKKPP RKKKNSQQDL NTPDTRPAGL EEADQPPLPG EQGINLDNSG 
PKLPEFSNRP PGYPSQPVEQ RPLQQMPPQL MQHVAPPPQP PQQQPQPQLP QQQQPPPPSQ 
PQSQQQQQQQ QQMMMMLMMQ QDPKSVRLPV SQNVHPPRGP LNPDSQRMPM QQSGSVPVMV 
SLQGPASVPP SPDKQRMPMP VNTPLGSNSR KMVYQESPQN PSSSPLAEMA SLPEASGSEA 
PSVPGGPNNM PSHVVLPQNQ LMMTGPKPGP SPLSATQGAT PQQPPVNSLP SSHGHHFPNV 
AAPTQTSRPK TPNRASPRPY YPQTPNNRPP STEPSEISLS PERLNASIAG LFPPQINIPL 
PPRPNLNRGF DQQGLNPTTL KAIGQAPSNL TMNPSNFATP QTHKLDSVVV NSGKQSNSGA 
TKRASPSNSR RSSPGSSRKT TPSPGRQNSK APKLTLASQT NAALLQNVEL PRNVLVSPTP 
LANPPVPGSF PNNSGLNPQN STVSVAAVGG VVEDNKESLN VPQDSDCQNS QSRKEQVNIE 
LKAVPAQEVK MVVPEDQSKK DGQPSDPNKL PSVEENKNLV SPAMREAPTS LSQLLDNSGA 
PNVTIKPPGL TDLEVTPPVV SGEDLKKASV IPTLQDLSSS KEPSNSLNLP HSNELCSSLV 
HPELSEVSSN VAPSIPPVMS RPVSSSSIST PLPPNQITVF VTSNPITTSA NTSAALPTHL 
QSALMSTVVT MPNAGSKVMV SEGQSAAQSN ARPQFITPVF INSSSIIQVM KGSQPSTIPA 
APLTTNSGLM PPSVAVVGPL HIPQNIKFSS APVPPNALSS SPAPNIQTGR PLVLSSRATP 
VQLPSPPCTS SPVVPSHPPV QQVKELNPDE ASPQVNTSAD QNTLPSSQST TMVSPLLTNS 
PGSSGNRRSP VSSSKGKGKV DKIGQILLTK ACKKVTGSLE KGEEQYGADG ETEGQGLDTT 
APGLMGTEQL STELDSKTPT PPAPTLLKMT SSPVGPGTAS AGPSLPGGAL PTSVRSIVTT 
LVPSELISAV PTTKSNHGGI ASESLAGGLV EEKVGSHPEL LPSIAKMLRV PTTEW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.