Details for: HECW1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: Purkinje cell (CL0000121)
Fold Change: 4.68
Marker Score: 158,089 - Cell Name: stellate neuron (CL0000122)
Fold Change: 4.61
Marker Score: 24,739 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 4.14
Marker Score: 21,702 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 4.01
Marker Score: 13,451 - Cell Name: granule cell (CL0000120)
Fold Change: 3.95
Marker Score: 29,781 - Cell Name: macroglial cell (CL0000126)
Fold Change: 3.62
Marker Score: 8,319 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.87
Marker Score: 1,667 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 2.76
Marker Score: 1,236 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.56
Marker Score: 19,626 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.39
Marker Score: 90,845 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.39
Marker Score: 11,037 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 2.36
Marker Score: 1,132 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.34
Marker Score: 86,272 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.29
Marker Score: 9,505 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.28
Marker Score: 2,817 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.22
Marker Score: 8,566 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.19
Marker Score: 20,556 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.16
Marker Score: 4,092 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.15
Marker Score: 827 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.08
Marker Score: 127,901 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.03
Marker Score: 30,360 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2
Marker Score: 20,633 - Cell Name: precursor B cell (CL0000817)
Fold Change: 1.94
Marker Score: 1,284 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.93
Marker Score: 18,306 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.88
Marker Score: 37,384 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.88
Marker Score: 16,133 - Cell Name: neuron (CL0000540)
Fold Change: 1.87
Marker Score: 7,618 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.78
Marker Score: 2,153 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.71
Marker Score: 2,879 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.66
Marker Score: 2,555 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.66
Marker Score: 968 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1,168 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.57
Marker Score: 5,588 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.52
Marker Score: 637 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.48
Marker Score: 3,018 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.47
Marker Score: 3,466 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,393 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.34
Marker Score: 1,892 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.32
Marker Score: 740 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.26
Marker Score: 853 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.2
Marker Score: 1,499 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.19
Marker Score: 1,365 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.17
Marker Score: 487 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.16
Marker Score: 18,158 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.14
Marker Score: 347 - Cell Name: glial cell (CL0000125)
Fold Change: 1.08
Marker Score: 1,184 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.08
Marker Score: 1,138 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.07
Marker Score: 644 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,806 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,031 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 509 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,408 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 462 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.97
Marker Score: 1,304 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,331 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.93
Marker Score: 374 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.93
Marker Score: 254 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.92
Marker Score: 425 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,742 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 326 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,287 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.86
Marker Score: 3,591 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.84
Marker Score: 270 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.82
Marker Score: 258 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 708 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 397 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.74
Marker Score: 15,840 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.74
Marker Score: 252 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.72
Marker Score: 462 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.71
Marker Score: 338 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.71
Marker Score: 369 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.68
Marker Score: 2,846 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.66
Marker Score: 327 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 0.65
Marker Score: 627 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.65
Marker Score: 388 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.62
Marker Score: 6,243 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.59
Marker Score: 154 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.57
Marker Score: 452 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 0.56
Marker Score: 146 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.56
Marker Score: 176 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.55
Marker Score: 243 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.55
Marker Score: 154 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.53
Marker Score: 134 - Cell Name: T cell (CL0000084)
Fold Change: 0.52
Marker Score: 890 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.5
Marker Score: 326 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.48
Marker Score: 872 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.48
Marker Score: 414 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.47
Marker Score: 1,337 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.46
Marker Score: 882 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.44
Marker Score: 529 - Cell Name: podocyte (CL0000653)
Fold Change: 0.43
Marker Score: 159 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.42
Marker Score: 169 - Cell Name: immature B cell (CL0000816)
Fold Change: 0.42
Marker Score: 276 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.4
Marker Score: 1,657 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.39
Marker Score: 123 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.38
Marker Score: 112 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 0.38
Marker Score: 127 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.37
Marker Score: 214
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1143139464
Symbol: HECW1_HUMAN
Name: E3 ubiquitin-protein ligase HECW1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9205841
Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9205841
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14684739
Title: NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.
PubMed ID: 14684739
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
Sequence Information:
- Length: 1606
- Mass: 179554
- Checksum: 22AE698F16276E98
- Sequence:
MLLHLCSVKN LYQNRFLGLA AMASPSRNSQ SRRRCKEPLR YSYNPDQFHN MDLRGGPHDG VTIPRSTSDT DLVTSDSRST LMVSSSYYSI GHSQDLVIHW DIKEEVDAGD WIGMYLIDEV LSENFLDYKN RGVNGSHRGQ IIWKIDASSY FVEPETKICF KYYHGVSGAL RATTPSVTVK NSAAPIFKSI GADETVQGQG SRRLISFSLS DFQAMGLKKG MFFNPDPYLK ISIQPGKHSI FPALPHHGQE RRSKIIGNTV NPIWQAEQFS FVSLPTDVLE IEVKDKFAKS RPIIKRFLGK LSMPVQRLLE RHAIGDRVVS YTLGRRLPTD HVSGQLQFRF EITSSIHPDD EEISLSTEPE SAQIQDSPMN NLMESGSGEP RSEAPESSES WKPEQLGEGS VPDGPGNQSI ELSRPAEEAA VITEAGDQGM VSVGPEGAGE LLAQVQKDIQ PAPSAEELAE QLDLGEEASA LLLEDGEAPA STKEEPLEEE ATTQSRAGRE EEEKEQEEEG DVSTLEQGEG RLQLRASVKR KSRPCSLPVS ELETVIASAC GDPETPRTHY IRIHTLLHSM PSAQGGSAAE EEDGAEEEST LKDSSEKDGL SEVDTVAADP SALEEDREEP EGATPGTAHP GHSGGHFPSL ANGAAQDGDT HPSTGSESDS SPRQGGDHSC EGCDASCCSP SCYSSSCYST SCYSSSCYSA SCYSPSCYNG NRFASHTRFS SVDSAKISES TVFSSQDDEE EENSAFESVP DSMQSPELDP ESTNGAGPWQ DELAAPSGHV ERSPEGLESP VAGPSNRREG ECPILHNSQP VSQLPSLRPE HHHYPTIDEP LPPNWEARID SHGRVFYVDH VNRTTTWQRP TAAATPDGMR RSGSIQQMEQ LNRRYQNIQR TIATERSEED SGSQSCEQAP AGGGGGGGSD SEAESSQSSL DLRREGSLSP VNSQKITLLL QSPAVKFITN PEFFTVLHAN YSAYRVFTSS TCLKHMILKV RRDARNFERY QHNRDLVNFI NMFADTRLEL PRGWEIKTDQ QGKSFFVDHN SRATTFIDPR IPLQNGRLPN HLTHRQHLQR LRSYSAGEAS EVSRNRGASL LARPGHSLVA AIRSQHQHES LPLAYNDKIV AFLRQPNIFE MLQERQPSLA RNHTLREKIH YIRTEGNHGL EKLSCDADLV ILLSLFEEEI MSYVPLQAAF HPGYSFSPRC SPCSSPQNSP GLQRASARAP SPYRRDFEAK LRNFYRKLEA KGFGQGPGKI KLIIRRDHLL EGTFNQVMAY SRKELQRNKL YVTFVGEEGL DYSGPSREFF FLLSQELFNP YYGLFEYSAN DTYTVQISPM SAFVENHLEW FRFSGRILGL ALIHQYLLDA FFTRPFYKAL LRLPCDLSDL EYLDEEFHQS LQWMKDNNIT DILDLTFTVN EEVFGQVTER ELKSGGANTQ VTEKNKKEYI ERMVKWRVER GVVQQTEALV RGFYEVVDSR LVSVFDAREL ELVIAGTAEI DLNDWRNNTE YRGGYHDGHL VIRWFWAAVE RFNNEQRLRL LQFVTGTSSV PYEGFAALRG SNGLRRFCIE KWGKITSLPR AHTCFNRLDL PPYPSYSMLY EKLLTAVEET STFGLE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.