Details for: EXPH5

Gene ID: 23086

Symbol: EXPH5

Ensembl ID: ENSG00000110723

Description: exophilin 5

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.52
    Marker Score: 3,391
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.28
    Marker Score: 2,754
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.97
    Marker Score: 1,150
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.96
    Marker Score: 1,309
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.87
    Marker Score: 7,809
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.84
    Marker Score: 6,327
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.83
    Marker Score: 2,068
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.76
    Marker Score: 7,321
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.74
    Marker Score: 1,429
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.74
    Marker Score: 758
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.7
    Marker Score: 1,793
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.63
    Marker Score: 1,800
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.54
    Marker Score: 13,370
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.5
    Marker Score: 1,024
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 1.49
    Marker Score: 2,160
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,704
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.45
    Marker Score: 10,777
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 1.43
    Marker Score: 1,415
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.4
    Marker Score: 653
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.39
    Marker Score: 22,293
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 1.32
    Marker Score: 1,589
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.25
    Marker Score: 869
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.22
    Marker Score: 1,581
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 1.22
    Marker Score: 2,319
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 1.2
    Marker Score: 406
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.17
    Marker Score: 434
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.16
    Marker Score: 336
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.15
    Marker Score: 545
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.14
    Marker Score: 1,207
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.13
    Marker Score: 7,251
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 1.11
    Marker Score: 358
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.07
    Marker Score: 1,065
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.05
    Marker Score: 304
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.04
    Marker Score: 515
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.04
    Marker Score: 304
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,804
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,028
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.99
    Marker Score: 593
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.99
    Marker Score: 5,215
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.99
    Marker Score: 3,885
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,406
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 504
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 458
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.97
    Marker Score: 2,203
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.95
    Marker Score: 556
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,410
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.95
    Marker Score: 299
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.95
    Marker Score: 14,796
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.94
    Marker Score: 4,062
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.92
    Marker Score: 7,901
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,733
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 323
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.89
    Marker Score: 792
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.89
    Marker Score: 1,626
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.89
    Marker Score: 5,064
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.88
    Marker Score: 681
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.88
    Marker Score: 1,787
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.88
    Marker Score: 947
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.88
    Marker Score: 461
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,280
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.87
    Marker Score: 752
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 0.86
    Marker Score: 4,610
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.83
    Marker Score: 631
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.82
    Marker Score: 963
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.82
    Marker Score: 5,367
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.82
    Marker Score: 4,412
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 0.79
    Marker Score: 855
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.79
    Marker Score: 770
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.79
    Marker Score: 315
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,264
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 393
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.73
    Marker Score: 1,729
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.73
    Marker Score: 668
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.73
    Marker Score: 333
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.73
    Marker Score: 3,044
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 0.71
    Marker Score: 3,745
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.7
    Marker Score: 1,753
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 178
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.66
    Marker Score: 23,004
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.66
    Marker Score: 25,179
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.66
    Marker Score: 397
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.66
    Marker Score: 362
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.65
    Marker Score: 247
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.64
    Marker Score: 1,398
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 0.63
    Marker Score: 389
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.63
    Marker Score: 160
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.63
    Marker Score: 636
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.62
    Marker Score: 285
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.61
    Marker Score: 274
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.59
    Marker Score: 838
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.58
    Marker Score: 930
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 0.58
    Marker Score: 185
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.58
    Marker Score: 340
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.58
    Marker Score: 1,323
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.58
    Marker Score: 197
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.58
    Marker Score: 1,026
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.58
    Marker Score: 501
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 442
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.54
    Marker Score: 869
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 0.54
    Marker Score: 518

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** EXPH5 is a synaptotagmin-like protein that lacks the C2 domains, which are essential for calcium-dependent binding to phospholipids. This unique structure allows EXPH5 to interact with other proteins and lipid molecules, regulating its functions. 2. **Expression:** EXPH5 is widely expressed in various tissues, including the lens, epithelial cells, and syncytiotrophoblast cells. Its expression is also observed in nasal mucosa goblet cells, pigmented epithelial cells, and ciliated cells. 3. **Protein Interactions:** EXPH5 interacts with other proteins, including those involved in endocytic and exocytic processes, such as Rab GTPases and clathrin. These interactions help regulate the sorting of multivesicular bodies and the positive regulation of protein secretion. **Pathways and Functions:** 1. **Endosome and Multivesicular Body Sorting Pathway:** EXPH5 plays a crucial role in regulating the sorting of multivesicular bodies, which are involved in the degradation and recycling of cellular components. This process is essential for maintaining cellular homeostasis and regulating protein secretion. 2. **Intracellular Protein Transport:** EXPH5 is involved in regulating the transport of proteins within the cell, including the sorting of proteins to the plasma membrane and the endoplasmic reticulum. 3. **Positive Regulation of Exocytosis:** EXPH5 regulates the positive regulation of exocytosis, which is the process by which cells release proteins and other molecules into the extracellular space. This process is essential for cellular communication and the regulation of various physiological responses. 4. **Positive Regulation of Protein Secretion:** EXPH5 also regulates the positive regulation of protein secretion, which is the process by which cells release proteins into the extracellular space. This process is essential for the regulation of various physiological responses, including immune responses and cellular communication. **Clinical Significance:** 1. **Eye Diseases:** EXPH5 has been implicated in various eye diseases, including cataracts and age-related macular degeneration. Mutations in the EXPH5 gene have been associated with these diseases, highlighting its importance in maintaining lens function and structure. 2. **Immunological Disorders:** EXPH5 has been implicated in various immunological disorders, including autoimmune diseases and allergies. Its role in regulating protein secretion and endocytic processes makes it an important player in the regulation of immune responses. 3. **Cancer:** EXPH5 has been implicated in various cancers, including breast cancer and lung cancer. Its role in regulating protein secretion and endocytic processes makes it an important player in the regulation of cancer cell growth and metastasis. In conclusion, EXPH5 is a multifunctional protein that plays a crucial role in regulating endocytic and exocytic processes, including the sorting of multivesicular bodies and the positive regulation of protein secretion. Its expression in various tissues and its involvement in various diseases highlight its importance in maintaining cellular homeostasis and regulating physiological responses. Further studies are necessary to fully elucidate the role of EXPH5 in human diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 9365101

Symbol: EXPH5_HUMAN

Name: Synaptotagmin-like protein homolog lacking C2 domains b

UniProtKB Accession Codes:

Q8NEV8 Q2KHM1 Q9Y4D6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12062444

Title: Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions.

PubMed ID: 12062444

DOI: 10.1016/s0014-5793(02)02634-0

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23176819

Title: Germline mutation in EXPH5 implicates the Rab27B effector protein SlaC2-b in inherited skin fragility.

PubMed ID: 23176819

DOI: 10.1016/j.ajhg.2012.10.012

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1989
  • Mass: 222520
  • Checksum: DE36430AD569628F
  • Sequence:
    • MTKVPPAFDF SFLNDEEARK ILQVLERNEE LQRAEKDRIS KLQKTKRDIR WLQGVTGEWF 
EEIQRKKFCN ETDVSQMLKQ PLTYRLSKEM AKNDPIELPT SRSKNVTNQK KPTPFSSRMS 
FRSSFASLFS FRKSGKETSK LPSLGQKGCD GHAGPPMPVR GAAVQAKIYN SPLENHLVDS 
TFVPKPAVMR EESGMPPPWD ASLLENEFFQ VLDDLDSKLA QEQSASSVNT RTPLNYGSRT 
QFGHFYSSGN RHGNITERHK KHYNETSNMS IYDILRPGTP REGFKTFSPR TSTIYDMYRT 
REPRVFKEDY VQKNTFGSTS LCFDSRQRSA LPATGHFTAR SLHFPATTQS KSGFIPPRHQ 
QSPKRTPLSS IIWNRSDSSR DRENQEEFLR APSPMEIDPA DKYVYPRGFQ ENKRYESYHS 
QNVYQRVSLN APMENAMSPD TFENSENMPF YHQSNTFTRS FFSNTFGRSG EQRRFGQGPF 
WGQEKGHSFW SDFHRSRKSF SSSDRDFEMI SMEANSVSAI HGHNVSSEHW ESFSSGYGTD 
VSRGQEEPHP WQFDFQRSTL DSMVVSHGNE TQLTPHFGTP NVCSMTGSSY HVKSSELVSQ 
QDSSPVEVHI NKEASSFGIA QTLASSFKTS FSQISDDRRN PQSPNLQNPT VTLQKIFPNK 
PASHPMRSHT EVTVTSSNSV DSLPLAKSQP NILVTEVNNE KDLNESISEE DKQLSKMDQT 
NKAGEIPQPV SQTGISNSLP DFQNPLSQDS AKSNGFGFNA STIISSKKSP RVFSRKDTSK 
MYIPHTDKSN DIKQDKRFTE NRKLGSTASL PFIQEHRTPP SFPRTDQGCH QELTVNNEDI 
SRIITNNHWS SALTDTQNAQ YSKCKLTPGH KTSCDSLDLS SAALPDSSPS KNSSLDAPVV 
PSTTVFSRRS PSDKDPSLGE REEKDNAGKN QKNQFIVSHS ENQERNDSPV PTHDEVVDVK 
CHSHSPFRNE RGKGKIRHHI SCIEKLSKTE SISVPTSDHR SLIEANQSNS KVSELDTIYC 
TLPRKSSSFL IHGRQSGSKI MAASLRNGPP PFQIKNNVED AMGNYMLNKF SPSSPESANE 
CSKVLSDSAL EAPEATERMT NVKSSGSTSV RKGPLPFLIN RAMSCPSGEP HASTGREGRK 
KPLTSGMDAS ELTPRAWERI ISPVESDSSV RDCSLTKRQH QKENFQEYTE KEGKMAASRR 
SVFALSNEDP LPFCSDLSGK ERGKTLHKVK TTSTFSVSGD EDNVKCLEVV SIYYTLPRKP 
SKKFCNLLQQ YTQNTNLLIE SPQVETETFP NALEKDKQNY STREQSGTPS CENLKMSVNS 
DQTLTTENMT AFRLSNRGPL APTLQEMASV EAAVSLPEEE SKAREIFSDN LAKTPLGDSE 
NKKERGKKLQ SETLHTSLML QRKNVSEEKS ENCQQSINSS NSGPSSLPAL SEVNIGNSQT 
RRSSWECTGS GRAIPFTGSG KCPQKDHTST AVGDGSSGSQ PREGRGDIGT NCQKMTNKTL 
SHSESQVFAL TPALHKLQLG EETQSDEPNL ESLQSEPREL PQRSQEANMT ESRKAEDEMQ 
KSAWDQPSLP EGNKNKTNLD DLVKGENRSS VKHRLAAMSK ASRKFPAKDV SPRRHVATIF 
PQSGSRSGFD HLSLGTVECN PLFPEPTPKS AESIGESRLS ENGKHVKKSE NLLPITVLPN 
REPSTHVSNQ KSNSISQRHQ NEFKNVSESP SKHENSKDVT AAQNLVRESG APSPITFTSL 
REAEFSDNQR RLSPPFPLEP AQKSRVSSPL ASFLQQQRSA SSLEWEPEPH LYRSKSLKSI 
NVHGDLLRKS HPPKVRERHF SESTSIDNAL SRLTLGNEFS VNNGYSRRFR SFSELPSCDG 
NESWAYRSGT KTGPRSAISI YRPIDYGIFG KEQQLAFLEN VKRSLTQGRL WKPSFLKNPG 
FLKDDLRNPP NPSESLSSNS PSSQVPEDGL SPSEPLNIYE DDPVDSDCDT DTTTDDEYYL 
DENDKESEL

Genular Protein ID: 152389370

Symbol: B4E2C3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E2C3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GenomeRNAi 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 2 SAM 1

Sequence Information:

  • Length: 1192
  • Mass: 133532
  • Checksum: 26C949940CDBE054
  • Sequence:
    • MREESGMPPP WDASLLENEF FQVLDDLDSK LAQEQSASSV NTRTPLNYGS RTQFGHFYSS 
GNRHGNITER HKKHYNETSN MSIYDILRPG TPREGFKTFS PRTSTIYDMY RTREPRVFKE 
DYVQKNTFGS TSLCFDSRQR SALPATGHFT ARSLHFPATT QSKSGFIPPR HQQSPKRTPL 
SSIIWNRSDS SRDRENQEEF LRAPSPMEID PADKYVYPRG FQENKRYESY HSQNVYQRVS 
LNAPMENAMS PDTFENSENM PFYHQSNTFT RSFFSNTFGR SGEQRRFGQG PFWGQEKGHS 
FWSDFHRSRK SFSSSDRDFE MISMEANIVS AIHGHNVSSE HWESFSSGYG TDVSRGQEEP 
HPWQFDFQRS TLDSMVVSHG NETQLTPHFG TPNVCSMTGS SYHVKSSELV SQQDSSPVEV 
HINKEASSFG IAQTLASSFK TSFSQISDDR RNPQSPNLQN PTVTLQKIFP NKPASHPMRS 
HTEVTVTSSN SVDSLPLAKS QPNILVTEVN NEKDLNESIS EEDKQLSKMD QTNKAGEIPQ 
PVSQTGISNS LPDFQNPLSQ DSAKSNGFGF NASTIISSKK SPRVFSRKDT SKMYIPHTDK 
SNDIKQDKRF TENRKLGSTA SLPFIQEHRT PPSFPRTDQG CHQELTVNNE DISRIITNNH 
WSSALTDTQN AQYSKCKLTP GHKTSCDSLD LSSAALPDSS PSKNSSLDAP VVPSTTVFSR 
RSPSDKDPSL GEREEKDNAG KNQKNQFIVS HSENQERNDS PVPTHDEVVD VKCHSHSPFR 
NERGKGKIRH HISCIEKLSK TESISVPTSD HRSLIEANQS NSKVSELDTI YCTLPRKSSS 
FLIHGRQSGS KIMAASLRNG PPPFQIKNNV EDAMGNYMLN KFSPSSPESA NECSKVLSDS 
ALEAPEATER MTNVKSSGST SVRKGPLPFL INRAMSCPSG EPHASTGREG RKKPLTSGMD 
ASELTPRAWE RIISPVESDS SVRDCSLTKR QHQKENFQEY TEKEGKMAAS RRSVFALSNE 
DPLPFCSDLS GKERGKTLHK VKTTSTFSVS GDEDNVKCLE VVSIYYTLPR KPSKKFCNLL 
QQYTQNTNLL IESPQVETET FPNALEKDKQ NYSTREQSGT PSCENLKMSV NSDQTLTTEN 
MTAFRLSNRG PLAPTLQEMA SVEAAVSLPE EESKAREIFS DNLAKTPLGD SE

Genular Protein ID: 3655852939

Symbol: Q6AI59_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6AI59

Database IDs:

BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GenomeRNAi 1 IntAct 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 1733
  • Mass: 192925
  • Checksum: F218BE0FDD3805A8
  • Sequence:
    • MLKQPLTYRL SKEMAKNDPI ELPTSRSKNV TNQKKPTPFS SRMSFRSSFA SLFSFRKSGK 
ETSKLPSLGQ KGCDGHAGPP MPVRGAAVQA KIYNSPLENH LVDSTFVPKP AVMREESGMP 
PPWDASLLEN EFFQVLDDLD SKLAQEQSAS SVNTRTPLNY GSRTQFGHFY SSGNRHGNIT 
ERHKKHYNET SNMSIYDILR PGTPREGFKT FSPRTSTIYD MYRTREPRVF KEDYVQKNTF 
GSTSLCFDSR QRSALPATGH FTARSLHFPA TTQSKSGFIP PRHQQSPKRT PLSSIIWNRS 
DSSRDRENQE EFLRAPSPME IDPADKYVYP RGFQENKRYE SYHSQNVYQR VSLNAPMENA 
MSPDTFENSE NMPFHHQSNT FTRSFFSNTF GRSGEQRRFG QGPFWGQEKG HSFWSDFHRS 
RKSFSSSDRD FEMISMEANS VSAIHGHNVS SEHWESFSSG YGTDVSRGQE EPHPWQFDFQ 
RSTLDSMVVS HGNETQLTPH FGTPNVCSMT GSSYHVKSSE LVSQQDSSPV EVHINKEASS 
FGIAQTLASS FKTSFSQISD DRRNPQSPNL QNPTVTLQKI FPNKPASHPM GSHTEVTVTS 
SNSVDSLPLA KSQPNILVTE VNNEKDLNES ISEEDKQLSK MDQTNKAGEI PQPVSQTGIS 
NSLPDFQNPL SQDSAKSNGF GFNASTIISS KKSPRVFSRK DTSKMYIPHT DKSNDIKQDK 
RFTENRKLGS TASLPFIQEH RTPPSFPRTD QGCHQELTVN NEDISRIITN NHWSSALTDT 
QNAQYSKCKL TPGHKTSCDS LDLSSAALPD SSPSKNSSLD APVVPSTTVF SRRSPSDKDP 
SLGEREEKDN AGKNQKNQFI VSHSENQERN DSPVPTHDEV VDVKCHSHSP FRNERGKGKI 
RHHISCIEKL SKTESISVPT SDHRSLIEAN QSNSKVSELD TIYCTLPRKS SSFLIHGRQS 
GSKIMAASLR NGPPPFQIKN NVEDAMGNYM LNKFSPSSPE SANECSKVLS DSALEAPEAT 
ERMTNVKSSG STSVRKGPLP FLINRAMSCP SGEPHASTGR EGRKKPLTSG MDASELTPRA 
WERIISPVES DSSVRDCSLT KRQHQKENFQ EYTEKEGKMA ASRRSVFALS NEDPLPFCSD 
LSGKERGKTL HKVKTTSTFS VSGDEDNVKC LEVVSIYYTL PRKPSKKFCN LLQQYTQNTN 
LLIESPQVET ETFPNALEKD KQNYSTREQS GTPSCENLKM SVNSDQTLTT ENMTAFRLSN 
RGPLAPTLQE MASVEAAVSL PEEESKAREI FSDNLAKTPL GDSENKKERG KKLQSETLHT 
SLMLQRKNVS EEKSENCQQS INSSNSGPSS LPALSEVNIG NSQTRRSSWE CTGSGRAIPF 
TGSGKCPQKD HTSTAVGDGS SGSQPREGRG DIGTNCQKMT NKTLSHSESQ VFALTPALHK 
LQLGEETQSD EPNSESLQSE PRELPQRSQE ANMTESRKAE DEMQKSAWDQ PSLPEGNKNK 
TNLDDLVKGE NRSSVKHRLA AMSKASRKFP AKDVSPRRHV ATIFPQSGSR SGFDHLSLGT 
VECNPLFPEP TPKSAESIGE SRLSENGKHV KKSENLLPIT VLPNREPSTH VSNQKSNSIS 
QRHQNEFKNV SESPSKHENS KDVTAAQNLV RESGAPSPIT FTSLREAEFS DNQRRLSPPF 
PLEPAQKSRV SSPLASFLQQ QRSASSLEWE PEPHLYRSKS LKSINVHGDL LRK

Genular Protein ID: 1049651613

Symbol: B4E1U8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E1U8

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GenomeRNAi 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 819
  • Mass: 92664
  • Checksum: 23FB8F1EF62BB0E2
  • Sequence:
    • MPVRGAAVQA KIYNSPLENH LVDSTFVPKP AVMREESGMP PPWDASLLEN EFFQVLDDLD 
SKLAQEQSAS SVNTRTPLNY GSRAQFGHFY SSGNRHGNIT ERHKKHYNET SNMSIYDILR 
PGTPREGFKT FSPRTSTIYD MYRTREPRVF KEDYVQKNTF GSTSLCFDSR QRSALPATGH 
FTARSLHFPA TTQSKSGFIP PRHQQSPKRT PLSSIIWNRS DSSRDRENQE EFLRAPSPME 
IDPADKYVYP RGFQENKRYE SYHSQNVYQR VSLNAPMENA MSPDTFENSE NMPFYHQSNT 
FTRSFFSNTF GRSGEQRRFG QGPFWGQEKG HSFWSDFHRS RKSFSSSDRD FEMISMEANS 
VSAIHGHNVS SEHWESFSSG YGTDVSRGQE EPHPWQFDFQ RSTLDSMVVS HGNETQLTPH 
FGTPNVCSMT GSSYHVKSSE LVSQQDSSPV EVHINKEASS FGIAQTLASS FKTSFSQISD 
DRRNPQSPNL QNPTVTLQKI FPNKPASHPM RSHTEVTVTS SNSVDSLPLA KSQPNILVTE 
VNNENSKDVT AAQNLVRESG APSPITFTSL REAEFSDNQR RLSPPFPLEP AQKSRVSSPL 
ASFLQQQRSA SSLEWEPEPH LYRSKSLKSI NVHGDLLRKS HPPKVRERHF SESTSIDNAL 
SRLTLGNEFS VNNGYSRRFR SFSELPSCDG NESWAYRSGT KTGPRSAISI YRPIDYGIFG 
KEQQLAFLEN VKRSLTQGRL WKPSFLKNPG FLKDDLRNPP NPSESLSSNS PSSQVPEDGL 
SPSEPLNIYE DDPVDSDCDT DTTTDDEYYL DENDKESEL

Genular Protein ID: 3829648976

Symbol: Q149M6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q149M6

Database IDs:

BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 PharmGKB 1 RefSeq 5 SAM 1 iPTMnet 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1989
  • Mass: 222421
  • Checksum: 43751F7E54F66566
  • Sequence:
    • MTKVPPAFDF SFLNDEEAGK ILQVLERNEE LQRAEKDRIS KLQKTKRDIR WLQGVTGEWF 
EEIQRKKFCN ETDVSQMLKQ PLTYRLSKEM AKNDPIELPT SRSKNVTNQK KPTPFSSRMS 
FRSSFASLFS FRKSGKETSK LPSLGQKGCD GHAGPPMPVR GAAVQAKIYN SPLENHLVDS 
TFVPKPAVMR EESGMPPPWD ASLLENEFFQ VLDDLDSKLA QEQSASSVNT RTPLNYGSRT 
QFGHFYSSGN RHGNITERHK KHYNETSNMS IYDILRPGTP REGFKTFSPR TSTIYDMYRT 
REPRVFKEDY VQKNTFGSTS LCFDSRQRSA LPATGHFTAR SLHFPATTQS KSGFIPPRHQ 
QSPKRTPLSS IIWNRSDSSR DRENQEEFLR APSPMEIDPA DKYVYPRGFQ ENKRYESYHS 
QNVYQRVSLN APMENAMSPD TFENSENMPF YHQSNTFTRS FFSNTFGRSG EQRRFGQGPF 
WGQEKGHSFW SDFHRSRKSF SSSDRDFEMI SMEANSVSAI HGHNVSSEHW ESFSSGYGTD 
VSRGQEEPHP WQFDFQRSTL DSMVVSHGNE TQLTPHFGTP NVCSMTGSSY HVKSSELVSQ 
QDSSPVEVHI NKEASSFGIA QTLASSFKTS FSQISDDRRN PQSPNLQNPT VTLQKIFPNK 
PASHPMRSHT EVTVTSSNSV DSLPLAKSQP NILVTEVNNE KDLNESISEE DKQLSKMDQT 
NKAGEIPQPV SQTGISNSLP DFQNPLSQDS AKSNGFGFNA STIISSKKSP RVFSRKDTSK 
MYIPHTDKSN DIKQDKRFTE NRKLGSTASL PFIQEHRTPP SFPRTDQGCH QELTVNNEDI 
SRIITNNHWS SALTDTQNAQ YSKCKLTPGH KTSCDSLDLS SAALPDSSPS KNSSLDAPVV 
PSTTVFSRRS PSDKDPSLGE REEKDNAGKN QKNQFIVSHS ENQERNDSPV PTHDEVVDVK 
CHSHSPFRNE RGKGKIRHHI SCIEKLSKTE SISVPTSDHR SLIEANQSNS KVSELDTIYC 
TLPRKSSSFL IHGRQSGSKI MAASLRNGPP PFQIKNNVED AMGNYMLNKF SPSSPESANE 
CSKVLSDSAL EAPEATERMT NVKSSGSTSV RKGPLPFLIN RAMSCPSGEP HASTGREGRK 
KPLTSGMDAS ELTPRAWERI ISPVESDSSV RDCSLTKRQH QKENFQEYTE KEGKMAASRR 
SVFALSNEDP LPFCSDLSGK ERGKTLHKVK TTSTFSVSGD EDNVKCLEVV SIYYTLPRKP 
SKKFCNLLQQ YTQNTNLLIE SPQVETETFP NALEKDKQNY STREQSGTPS CENLKMSVNS 
DQTLTTENMT AFRLSNRGPL APTLQEMASV EAAVSLPEEE SKAREIFSDN LAKTPLGDSE 
NKKERGKKLQ SETLHTSLML QRKNVSEEKS ENCQQSINSS NSGPSSLPAL SEVNIGNSQT 
RRSSWECTGS GRAIPFTGSG KCPQKDHTST AVGDGSSGSQ PREGRGDIGT NCQKMTNKTL 
SHSESQVFAL TPALHKLQLG EETQSDEPNL ESLQSEPREL PQRSQEANMT ESRKAEDEMQ 
KSAWDQPSLP EGNKNKTNLD DLVKGENRSS VKHRLAAMSK ASRKFPAKDV SPRRHVATIF 
PQSGSRSGFD HLSLGTVECN PLFPEPTPKS AESIGESRLS ENGKHVKKSE NLLPITVLPN 
REPSTHVSNQ KSNSISQRHQ NEFKNVSESP SKHENSKDVT AAQNLVRESG APSPITFTSL 
REAEFSDNQR RLSPPFPLEP AQKSRVSSPL ASFLQQQRSA SSLEWEPEPH LYRSKSLKSI 
NVHGDLLRKS HPPKVRERHF SESTSIDNAL SRLTLGNEFS VNNGYSRRFR SFSELPSCDG 
NESWAYRSGT KTGPRSAISI YRPIDYGIFG KEQQLAFLEN VKRSLTQGRL WKPSFLKNPG 
FLKDDLRNPP NPSESLSSNS PSSQVPEDGL SPSEPLNIYE DDPVDSDCDT DTTTDDEYYL 
DENDKESEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.