Details for: PEG10

Gene ID: 23089

Symbol: PEG10

Ensembl ID: ENSG00000242265

Description: paternally expressed 10

Associated with

Other Information

Genular Protein ID: 194786186

Symbol: PEG10_HUMAN

Name: Retrotransposon gag domain-containing protein 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11318613

Title: A retrotransposon-derived gene, PEG10, is a novel imprinted gene located on human chromosome 7q21.

PubMed ID: 11318613

DOI: 10.1006/geno.2001.6494

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12620933

Title: Temporal regulation of the expression of syncytin (HERV-W), maternally imprinted PEG10, and SGCE in human placenta.

PubMed ID: 12620933

DOI: 10.1095/biolreprod.102.013078

PubMed ID: 12810624

Title: Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.

PubMed ID: 12810624

PubMed ID: 15611116

Title: Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.

PubMed ID: 15611116

DOI: 10.1074/jbc.m409197200

PubMed ID: 16423995

Title: PEG10 is a c-MYC target gene in cancer cells.

PubMed ID: 16423995

DOI: 10.1158/0008-5472.can-05-1553

PubMed ID: 17050006

Title: Glycogen synthase kinase-3beta binds to E2F1 and regulates its transcriptional activity.

PubMed ID: 17050006

DOI: 10.1016/j.bbamcr.2006.09.015

PubMed ID: 17621626

Title: Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia.

PubMed ID: 17621626

DOI: 10.1002/ijc.22929

PubMed ID: 17942406

Title: Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues.

PubMed ID: 17942406

DOI: 10.1074/jbc.m705676200

PubMed ID: 17369855

Title: Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells.

PubMed ID: 17369855

DOI: 10.1038/sj.onc.1210362

PubMed ID: 18625225

Title: PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma.

PubMed ID: 18625225

DOI: 10.1016/j.febslet.2008.07.009

PubMed ID: 20362226

Title: PEG10 is a probable target for the amplification at 7q21 detected in hepatocellular carcinoma.

PubMed ID: 20362226

DOI: 10.1016/j.cancergencyto.2010.01.004

PubMed ID: 21677654

Title:

PubMed ID: 21677654

DOI: 10.1038/onc.2011.66

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 20084274

Title: Genetic and molecular analyses of PEG10 reveal new aspects of genomic organization, transcription and translation.

PubMed ID: 20084274

DOI: 10.1371/journal.pone.0008686

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 26235627

Title: The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer.

PubMed ID: 26235627

DOI: 10.1016/j.celrep.2015.07.012

PubMed ID: 28193232

Title: PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer.

PubMed ID: 28193232

DOI: 10.1186/s13046-017-0500-x

PubMed ID: 28992046

Title: Phosphorylated E2F1 is stabilized by nuclear USP11 to drive Peg10 gene expression and activate lung epithelial cells.

PubMed ID: 28992046

DOI: 10.1093/jmcb/mjx034

PubMed ID: 30094509

Title: PEG10 counteracts signaling pathways of TGF-beta and BMP to regulate growth, motility and invasion of SW1353 chondrosarcoma cells.

PubMed ID: 30094509

DOI: 10.1007/s00774-018-0946-8

PubMed ID: 34413232

Title: Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery.

PubMed ID: 34413232

DOI: 10.1126/science.abg6155

PubMed ID: 34357660

Title: Structural evidence that MOAP1 and PEG10 are derived from retrovirus/retrotransposon Gag proteins.

PubMed ID: 34357660

DOI: 10.1002/prot.26204

Sequence Information:

  • Length: 708
  • Mass: 80173
  • Checksum: BFAA2FA24941D5D1
  • Sequence:
  • MTERRRDELS EEINNLREKV MKQSEENNNL QSQVQKLTEE NTTLREQVEP TPEDEDDDIE 
    LRGAAAAAAP PPPIEEECPE DLPEKFDGNP DMLAPFMAQC QIFMEKSTRD FSVDRVRVCF 
    VTSMMTGRAA RWASAKLERS HYLMHNYPAF MMEMKHVFED PQRREVAKRK IRRLRQGMGS 
    VIDYSNAFQM IAQDLDWNEP ALIDQYHEGL SDHIQEELSH LEVAKSLSAL IGQCIHIERR 
    LARAAAARKP RSPPRALVLP HIASHHQVDP TEPVGGARMR LTQEEKERRR KLNLCLYCGT 
    GGHYADNCPA KASKSSPAGK LPGPAVEGPS ATGPEIIRSP QDDASSPHLQ VMLQIHLPGR 
    HTLFVRAMID SGASGNFIDH EYVAQNGIPL RIKDWPILVE AIDGRPIASG PVVHETHDLI 
    VDLGDHREVL SFDVTQSPFF PVVLGVRWLS THDPNITWST RSIVFDSEYC RYHCRMYSPI 
    PPSLPPPAPQ PPLYYPVDGY RVYQPVRYYY VQNVYTPVDE HVYPDHRLVD PHIEMIPGAH 
    SIPSGHVYSL SEPEMAALRD FVARNVKDGL ITPTIAPNGA QVLQVKRGWK LQVSYDCRAP 
    NNFTIQNQYP RLSIPNLEDQ AHLATYTEFV PQIPGYQTYP TYAAYPTYPV GFAWYPVGRD 
    GQGRSLYVPV MITWNPHWYR QPPVPQYPPP QPPPPPPPPP PPPSYSTL

Genular Protein ID: 64665881

Symbol: A0A087WZG9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 359
  • Mass: 40490
  • Checksum: BDB5693F52C39834
  • Sequence:
  • MGPDCPPPPP PPPPNNNNNN NSKHTGHKSA CVPNMTERRR DELSEEINNL REKVMKQSEE 
    NNNLQSQVQK LTEENTTLRE QVEPTPEDED DDIELRGAAA AAAPPPPIEE ECPEDLPEKF 
    DGNPDMLAPF MAQCQIFMEK STRDFSVDRV RVCFVTSMMT GRAARWASAK LERSHYLMHN 
    YPAFMMEMKH VFEDPQRREV AKRKIRRLRQ GMGSVIDYSN AFQMIAQDLD WNEPALIDQY 
    HEGLSDHIQE ELSHLEVAKS LSALIGQCIH IERRLARAAA ARKPRSPPRA LVLPHIASHH 
    QVDPTEPVGG ARMRLTQEEK ERRRKLNLCL YCGTGGHYAD NCPAKASKSS PAGNSPAPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.