Details for: CLASP2

Gene ID: 23122

Symbol: CLASP2

Ensembl ID: ENSG00000163539

Description: cytoplasmic linker associated protein 2

Associated with

Other Information

Genular Protein ID: 181634691

Symbol: CLAP2_HUMAN

Name: CLIP-associating protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11290329

Title: Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

PubMed ID: 11290329

DOI: 10.1016/s0092-8674(01)00288-4

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15207236

Title: The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance.

PubMed ID: 15207236

DOI: 10.1016/j.neuron.2004.05.020

PubMed ID: 15631994

Title: CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.

PubMed ID: 15631994

DOI: 10.1083/jcb.200405094

PubMed ID: 15955847

Title: Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cells.

PubMed ID: 15955847

DOI: 10.1083/jcb.200412114

PubMed ID: 16824950

Title: CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.

PubMed ID: 16824950

DOI: 10.1016/j.devcel.2006.05.012

PubMed ID: 16866869

Title: Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.

PubMed ID: 16866869

DOI: 10.1111/j.1365-2443.2006.00990.x

PubMed ID: 16914514

Title: Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.

PubMed ID: 16914514

DOI: 10.1091/mbc.e06-07-0579

PubMed ID: 17543864

Title: Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.

PubMed ID: 17543864

DOI: 10.1016/j.devcel.2007.04.002

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19632184

Title: An EB1-binding motif acts as a microtubule tip localization signal.

PubMed ID: 19632184

DOI: 10.1016/j.cell.2009.04.065

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20937854

Title: ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.

PubMed ID: 20937854

DOI: 10.1073/pnas.1000975107

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 33587225

Title: SOGA1 and SOGA2/MTCL1 are CLASP-interacting proteins required for faithful chromosome segregation in human cells.

PubMed ID: 33587225

DOI: 10.1007/s10577-021-09651-8

PubMed ID: 26003921

Title: CLASP2 has two distinct TOG domains that contribute differently to microtubule dynamics.

PubMed ID: 26003921

DOI: 10.1016/j.jmb.2015.05.012

Sequence Information:

  • Length: 1294
  • Mass: 141064
  • Checksum: EAD31F728BC63B4B
  • Sequence:
  • MAMGDDKSFD DEESVDGNRP SSAASAFKVP APKTSGNPAN SARKPGSAGG PKVGGASKEG 
    GAGAVDEDDF IKAFTDVPSI QIYSSRELEE TLNKIREILS DDKHDWDQRA NALKKIRSLL 
    VAGAAQYDCF FQHLRLLDGA LKLSAKDLRS QVVREACITV AHLSTVLGNK FDHGAEAIVP 
    TLFNLVPNSA KVMATSGCAA IRFIIRHTHV PRLIPLITSN CTSKSVPVRR RSFEFLDLLL 
    QEWQTHSLER HAAVLVETIK KGIHDADAEA RVEARKTYMG LRNHFPGEAE TLYNSLEPSY 
    QKSLQTYLKS SGSVASLPQS DRSSSSSQES LNRPFSSKWS TANPSTVAGR VSAGSSKASS 
    LPGSLQRSRS DIDVNAAAGA KAHHAAGQSV RSGRLGAGAL NAGSYASLED TSDKLDGTAS 
    EDGRVRAKLS APLAGMGNAK ADSRGRSRTK MVSQSQPGSR SGSPGRVLTT TALSTVSSGV 
    QRVLVNSASA QKRSKIPRSQ GCSREASPSR LSVARSSRIP RPSVSQGCSR EASRESSRDT 
    SPVRSFQPLA SRHHSRSTGA LYAPEVYGAS GPGYGISQSS RLSSSVSAMR VLNTGSDVEE 
    AVADALKKPA RRRYESYGMH SDDDANSDAS SACSERSYSS RNGSIPTYMR QTEDVAEVLN 
    RCASSNWSER KEGLLGLQNL LKNQRTLSRV ELKRLCEIFT RMFADPHGKR VFSMFLETLV 
    DFIQVHKDDL QDWLFVLLTQ LLKKMGADLL GSVQAKVQKA LDVTRESFPN DLQFNILMRF 
    TVDQTQTPSL KVKVAILKYI ETLAKQMDPG DFINSSETRL AVSRVITWTT EPKSSDVRKA 
    AQSVLISLFE LNTPEFTMLL GALPKTFQDG ATKLLHNHLR NTGNGTQSSM GSPLTRPTPR 
    SPANWSSPLT SPTNTSQNTL SPSAFDYDTE NMNSEDIYSS LRGVTEAIQN FSFRSQEDMN 
    EPLKRDSKKD DGDSMCGGPG MSDPRAGGDA TDSSQTALDN KASLLHSMPT HSSPRSRDYN 
    PYNYSDSISP FNKSALKEAM FDDDADQFPD DLSLDHSDLV AELLKELSNH NERVEERKIA 
    LYELMKLTQE ESFSVWDEHF KTILLLLLET LGDKEPTIRA LALKVLREIL RHQPARFKNY 
    AELTVMKTLE AHKDPHKEVV RSAEEAASVL ATSISPEQCI KVLCPIIQTA DYPINLAAIK 
    MQTKVIERVS KETLNLLLPE IMPGLIQGYD NSESSVRKAC VFCLVAVHAV IGDELKPHLS 
    QLTGSKMKLL NLYIKRAQTG SGGADPTTDV SGQS

Genular Protein ID: 516499180

Symbol: E7ERI8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1513
  • Mass: 165628
  • Checksum: 584449B4359CE7C0
  • Sequence:
  • MEPRSMEYFC AQVQQKDVGG RLQVGQELLL YLGAPGAISD LEEDLGRLGK TVDALTGWVG 
    SSNYRVSLMG LEILSAFVDR LSTRFKSYVA MVIVALIDRM GDAKDKVRDE AQTLILKLMD 
    QVAPPMYIWE QLASGFKHKN FRSREGVCLC LIETLNIFGA QPLVISKLIP HLCILFGDSN 
    SQVRDAAILA IVEIYRHVGE KVRMDLYKRG IPPARLEMIF AKFDEVQSSG GMILSVCKDK 
    SFDDEESVDG NRPSSAASAF KVPAPKTSGN PANSARKPGS AGGPKVGGAS KEGGAGAVDE 
    DDFIKAFTDV PSIQIYSSRE LEETLNKIRE ILSDDKHDWD QRANALKKIR SLLVAGAAQY 
    DCFFQHLRLL DGALKLSAKD LRSQVVREAC ITVAHLSTVL GNKFDHGAEA IVPTLFNLVP 
    NSAKVMATSG CAAIRFIIRH THVPRLIPLI TSNCTSKSVP VRRRSFEFLD LLLQEWQTHS 
    LERHAAVLVE TIKKGIHDAD AEARVEARKT YMGLRNHFPG EAETLYNSLE PSYQKSLQTY 
    LKSSGSVASL PQSDRSSSSS QESLNRPFSS KWSTANPSTV AGRVSAGSSK ASSLPGSLQR 
    SRSDIDVNAA AGAKAHHAAG QSVRSGRLGA GALNAGSYAS LEDTSDKLDG TASEDGRVRA 
    KLSAPLAGMG NAKADSRGRS RTKMVSQSQP GSRSGSPGRV LTTTALSTVS SGVQRVLVNS 
    ASAQKRSKIP RSQGCSREAS PSRLSVARSS RIPRPSVSQG CSREASRESS RDTSPVRSFQ 
    PLGPGYGISQ SSRLSSSVSA MRVLNTGSDV EEAVADALLL GDIRTKKKPA RRRYESYGMH 
    SDDDANSDAS SACSERSYSS RNGSIPTYMR QTEDVAEVLN RCASSNWSER KEGLLGLQNL 
    LKNQRTLSRV ELKRLCEIFT RMFADPHGKV FSMFLETLVD FIQVHKDDLQ DWLFVLLTQL 
    LKKMGADLLG SVQAKVQKAL DVTRESFPND LQFNILMRFT VDQTQTPSLK VKVAILKYIE 
    TLAKQMDPGD FINSSETRLA VSRVITWTTE PKSSDVRKAA QSVLISLFEL NTPEFTMLLG 
    ALPKTFQDGA TKLLHNHLRN TGNGTQSSMG SPLTRPTPRS PANWSSPLTS PTNTSQNTLS 
    PSAFDYDTEN MNSEDIYSSL RGVTEAIQNF SFRSQEDMNE PLKRDSKKDD GDSMCGGPGM 
    SDPRAGGDAT DSSQTALDNK ASLLHSMPTH SSPRSRDYNP YNYSDSISPF NKSALKEAMF 
    DDDADQFPDD LSLDHSDLVA ELLKELSNHN ERVEERKIAL YELMKLTQEE SFSVWDEHFK 
    TILLLLLETL GDKEPTIRAL ALKVLREILR HQPARFKNYA ELTVMKTLEA HKDPHKEVVR 
    SAEEAASVLA TSISPEQCIK VLCPIIQTAD YPINLAAIKM QTKVIERVSK ETLNLLLPEI 
    MPGLIQGYDN SESSVRKACV FCLVAVHAVI GDELKPHLSQ LTGSKMKLLN LYIKRAQTGS 
    GGADPTTDVS GQS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.