GPD1L | ENSG00000152642 | NCBI 23171

Details for: GPD1L

Gene ID: 23171

Symbol: GPD1L

Ensembl ID: ENSG00000152642

Description: glycerol-3-phosphate dehydrogenase 1 like

Associated with

Glycerophospholipid biosynthesis
(R-HSA-1483206)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Phospholipid metabolism
(R-HSA-1483257)
Synthesis of pa
(R-HSA-1483166)
Carbohydrate metabolic process
(GO:0005975)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Glycerol-3-phosphate catabolic process
(GO:0046168)
Glycerol-3-phosphate dehydrogenase complex
(GO:0009331)
Glycerol-3-phosphate dehydrogenase [nad(p)+] activity
(GO:0047952)
Nad binding
(GO:0051287)
Nadh oxidation
(GO:0006116)
Nad metabolic process
(GO:0019674)
Negative regulation of peptidyl-serine phosphorylation
(GO:0033137)
Negative regulation of protein kinase c signaling
(GO:0090038)
Plasma membrane
(GO:0005886)
Positive regulation of protein localization to cell surface
(GO:2000010)
Positive regulation of sodium ion transport
(GO:0010765)
Protein homodimerization activity
(GO:0042803)
Regulation of heart rate
(GO:0002027)
Regulation of sodium ion transmembrane transporter activity
(GO:2000649)
Regulation of ventricular cardiac muscle cell membrane depolarization
(GO:0060373)
Sodium channel regulator activity
(GO:0017080)
Transmembrane transporter binding
(GO:0044325)
Ventricular cardiac muscle cell action potential
(GO:0086005)

Other Information

Proteins

Glycerol-3-phosphate dehydrogenase 1-like protein

Genular Protein ID: 3759260572

Symbol: GPD1L_HUMAN

Name: Glycerol-3-phosphate dehydrogenase 1-like protein

UniProtKB Accession Codes:

Q8N335 A8K9U3 Q14702 Q9BRM5

Database IDs:

Citations:

PubMed ID: 7788527

Title: Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7788527

DOI: 10.1093/dnares/2.1.37

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19666841

Title: GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.

PubMed ID: 19666841

DOI: 10.1152/ajpheart.00513.2009

PubMed ID: 19745168

Title: Cardiac Na+ current regulation by pyridine nucleotides.

PubMed ID: 19745168

DOI: 10.1161/circresaha.109.197277

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 17967976

Title: Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome.

PubMed ID: 17967976

DOI: 10.1161/circulationaha.107.704627

PubMed ID: 17967977

Title: Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.

PubMed ID: 17967977

DOI: 10.1161/circulationaha.107.703330

Sequence Information:

Length: 351
Mass: 38419
Checksum: 74C3B27EEB41DE89
Sequence:

MAAAPLKVCI VGSGNWGSAV AKIIGNNVKK LQKFASTVKM WVFEETVNGR KLTDIINNDH 
ENVKYLPGHK LPENVVAMSN LSEAVQDADL LVFVIPHQFI HRICDEITGR VPKKALGITL 
IKGIDEGPEG LKLISDIIRE KMGIDISVLM GANIANEVAA EKFCETTIGS KVMENGLLFK 
ELLQTPNFRI TVVDDADTVE LCGALKNIVA VGAGFCDGLR CGDNTKAAVI RLGLMEMIAF 
ARIFCKGQVS TATFLESCGV ADLITTCYGG RNRRVAEAFA RTGKTIEELE KEMLNGQKLQ 
GPQTSAEVYR ILKQKGLLDK FPLFTAVYQI CYESRPVQEM LSCLQSHPEH T

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: GPD1L

Associated with

Other Information

Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. PubMed ID: 7788527

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A. PubMed ID: 19666841

Cardiac Na+ current regulation by pyridine nucleotides. PubMed ID: 19745168

Initial characterization of the human central proteome. PubMed ID: 21269460

Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome. PubMed ID: 17967976

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias. PubMed ID: 17967977