Details for: GANAB

Gene ID: 23193

Symbol: GANAB

Ensembl ID: ENSG00000089597

Description: glucosidase II alpha subunit

Associated with

Other Information

Genular Protein ID: 3995555444

Symbol: GANAB_HUMAN

Name: Neutral alpha-glucosidase AB

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10929008

Title: The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo.

PubMed ID: 10929008

DOI: 10.1093/glycob/10.8.815

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 7788527

Title: Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7788527

DOI: 10.1093/dnares/2.1.37

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3881423

Title: Identity of neutral alpha-glucosidase AB and the glycoprotein processing enzyme glucosidase II. Biochemical and genetic studies.

PubMed ID: 3881423

DOI: 10.1016/s0021-9258(20)71234-2

PubMed ID: 8910335

Title: Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit.

PubMed ID: 8910335

DOI: 10.1074/jbc.271.44.27509

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27259053

Title: Mutations in GANAB, encoding the glucosidase IIalpha subunit, cause autosomal-dominant polycystic kidney and liver disease.

PubMed ID: 27259053

DOI: 10.1016/j.ajhg.2016.05.004

PubMed ID: 28375157

Title: Isolated polycystic liver disease genes define effectors of polycystin-1 function.

PubMed ID: 28375157

DOI: 10.1172/jci90129

PubMed ID: 33097077

Title: Novel GANAB variants associated with polycystic liver disease.

PubMed ID: 33097077

DOI: 10.1186/s13023-020-01585-4

Sequence Information:

  • Length: 944
  • Mass: 106874
  • Checksum: 9E3426FE9A016BF1
  • Sequence:
  • MAAVAAVAAR RRRSWASLVL AFLGVCLGIT LAVDRSNFKT CEESSFCKRQ RSIRPGLSPY 
    RALLDSLQLG PDSLTVHLIH EVTKVLLVLE LQGLQKNMTR FRIDELEPRR PRYRVPDVLV 
    ADPPIARLSV SGRDENSVEL TMAEGPYKII LTARPFRLDL LEDRSLLLSV NARGLLEFEH 
    QRAPRVSQGS KDPAEGDGAQ PEETPRDGDK PEETQGKAEK DEPGAWEETF KTHSDSKPYG 
    PMSVGLDFSL PGMEHVYGIP EHADNLRLKV TEGGEPYRLY NLDVFQYELY NPMALYGSVP 
    VLLAHNPHRD LGIFWLNAAE TWVDISSNTA GKTLFGKMMD YLQGSGETPQ TDVRWMSETG 
    IIDVFLLLGP SISDVFRQYA SLTGTQALPP LFSLGYHQSR WNYRDEADVL EVDQGFDDHN 
    LPCDVIWLDI EHADGKRYFT WDPSRFPQPR TMLERLASKR RKLVAIVDPH IKVDSGYRVH 
    EELRNLGLYV KTRDGSDYEG WCWPGSAGYP DFTNPTMRAW WANMFSYDNY EGSAPNLFVW 
    NDMNEPSVFN GPEVTMLKDA QHYGGWEHRD VHNIYGLYVH MATADGLRQR SGGMERPFVL 
    ARAFFAGSQR FGAVWTGDNT AEWDHLKISI PMCLSLGLVG LSFCGADVGG FFKNPEPELL 
    VRWYQMGAYQ PFFRAHAHLD TGRREPWLLP SQHNDIIRDA LGQRYSLLPF WYTLLYQAHR 
    EGIPVMRPLW VQYPQDVTTF NIDDQYLLGD ALLVHPVSDS GAHGVQVYLP GQGEVWYDIQ 
    SYQKHHGPQT LYLPVTLSSI PVFQRGGTIV PRWMRVRRSS ECMKDDPITL FVALSPQGTA 
    QGELFLDDGH TFNYQTRQEF LLRRFSFSGN TLVSSSADPE GHFETPIWIE RVVIIGAGKP 
    AAVVLQTKGS PESRLSFQHD PETSVLVLRK PGINVASDWS IHLR

Genular Protein ID: 3250580934

Symbol: F5H6X6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 847
  • Mass: 96216
  • Checksum: 68FE62252A5B076E
  • Sequence:
  • MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY KIILTARPFR 
    LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD GAQPEETPRD GDKPEETQGK 
    AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD FSLPGMEHVY GIPEHADNLR LKVTEGGEPY 
    RLYNLDVFQY ELYNPMALYG SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK 
    MMDYLQGSGE TPQTDVRWMS ETGIIDVFLL LGPSISDVFR QYASLTGTQA LPPLFSLGYH 
    QSRWNYRDEA DVLEVDQGFD DHNLPCDVIW LDIEHADGKR YFTWDPSRFP QPRTMLERLA 
    SKRRKLVAIV DPHIKVDSGY RVHEELRNLG LYVKTRDGSD YEGWCWPGSA GYPDFTNPTM 
    RAWWANMFSY DNYEGSAPNL FVWNDMNEPS VFNGPEVTML KDAQHYGGWE HRDVHNIYGL 
    YVHMATADGL RQRSGGMERP FVLARAFFAG SQRFGAVWTG DNTAEWDHLK ISIPMCLSLG 
    LVGLSFCGAD VGGFFKNPEP ELLVRWYQMG AYQPFFRAHA HLDTGRREPW LLPSQHNDII 
    RDALGQRYSL LPFWYTLLYQ AHREGIPVMR PLWVQYPQDV TTFNIDDQYL LGDALLVHPV 
    SDSGAHGVQV YLPGQGEVWY DIQSYQKHHG PQTLYLPVTL SSIPVFQRGG TIVPRWMRVR 
    RSSECMKDDP ITLFVALSPQ GTAQGELFLD DGHTFNYQTR QEFLLRRFSF SGNTLVSSSA 
    DPEGHFETPI WIERVVIIGA GKPAAVVLQT KGSPESRLSF QHDPETSVLV LRKPGINVAS 
    DWSIHLR

Genular Protein ID: 4119748563

Symbol: B4DZ53_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 852
  • Mass: 96528
  • Checksum: 53D99D0C0060233F
  • Sequence:
  • MAAVAAVAAR RRRLSVSGRD ENSVELTMAE GPYKIILTAR PFRLDLLEDR SLLLSVNARG 
    LLEFEHQRDP RVSFSDKVNL TLGSIWDKIK NLFSRQGSKD PAEGDGAQPE ETPRDGDKPE 
    ETQGKAEKDE PGAWEETFKT HSDSKPYGPM SVGLDFSLPG MEHVYGIPEH ADNLRLRVTE 
    GGEPYRLYNL DVFQYELYNP MALYGSVPVL LAHNPHRDLG IFWLNAAETW VDISSNTAGK 
    TLFGKMMDYL QGSGETPQTD VRWMSETGII DVFLLLGPSI SDVFRQYASL TGTQALPPLF 
    SLGYHQSRWN YRDEADVLEV DQGFDDHNLP CDVIRLDIEH ADGKRYFTWD PSRFPQPRTM 
    LERLASKRRK LVAIVDPHIK VDSGYRVHEE LRNLGLYVKT RDGSDYEGWC WPGSAGYPDF 
    TNPTMRAWWA NMFSYDNYEG SAPNLFVWND MNEPSVFNGP EVTMLKDAQH YGGWEHRDVH 
    NIYGLYVHMA TADGLRQRSG GMERPFVLAR AFFAGSQRFG AVWTGDNTAE WDHLKISIPM 
    CLSLGLVGLS FCGADVGGFF KNPEPELLVR WYQMGAYQPF FRAHAHLDTG RREPWLLPSQ 
    HNDIIRDALG QRYSLLPFWY TLLYQAHREG IPVMRPLWVQ YPQDVTTFNI GDQYLLGDAL 
    LVHPVSDSGA HGVQVYLPGQ GEVWYDIQSY QKHHGPQTLY LPVTLSSIPV FQRGGTIVPR 
    WMRVRRSSEC MKDDPITLFV ALSPQGTAQG ELFLDDGHTF NYQTRQEFLL RRFSFSGNTL 
    VSSSADPEGH FETPIWIERV VIIGAGKPAA VVLQTKGSPE SRLSFQHDPE TSVLVLRKPG 
    INVASDWSIH LR

Genular Protein ID: 2149260021

Symbol: E9PKU7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 852
  • Mass: 96544
  • Checksum: D4E65914B91010E3
  • Sequence:
  • MAAVAAVAAR RRRLSVSGRD ENSVELTMAE GPYKIILTAR PFRLDLLEDR SLLLSVNARG 
    LLEFEHQRAP RVSFSDKVNL TLGSIWDKIK NLFSRQGSKD PAEGDGAQPE ETPRDGDKPE 
    ETQGKAEKDE PGAWEETFKT HSDSKPYGPM SVGLDFSLPG MEHVYGIPEH ADNLRLKVTE 
    GGEPYRLYNL DVFQYELYNP MALYGSVPVL LAHNPHRDLG IFWLNAAETW VDISSNTAGK 
    TLFGKMMDYL QGSGETPQTD VRWMSETGII DVFLLLGPSI SDVFRQYASL TGTQALPPLF 
    SLGYHQSRWN YRDEADVLEV DQGFDDHNLP CDVIWLDIEH ADGKRYFTWD PSRFPQPRTM 
    LERLASKRRK LVAIVDPHIK VDSGYRVHEE LRNLGLYVKT RDGSDYEGWC WPGSAGYPDF 
    TNPTMRAWWA NMFSYDNYEG SAPNLFVWND MNEPSVFNGP EVTMLKDAQH YGGWEHRDVH 
    NIYGLYVHMA TADGLRQRSG GMERPFVLAR AFFAGSQRFG AVWTGDNTAE WDHLKISIPM 
    CLSLGLVGLS FCGADVGGFF KNPEPELLVR WYQMGAYQPF FRAHAHLDTG RREPWLLPSQ 
    HNDIIRDALG QRYSLLPFWY TLLYQAHREG IPVMRPLWVQ YPQDVTTFNI DDQYLLGDAL 
    LVHPVSDSGA HGVQVYLPGQ GEVWYDIQSY QKHHGPQTLY LPVTLSSIPV FQRGGTIVPR 
    WMRVRRSSEC MKDDPITLFV ALSPQGTAQG ELFLDDGHTF NYQTRQEFLL RRFSFSGNTL 
    VSSSADPEGH FETPIWIERV VIIGAGKPAA VVLQTKGSPE SRLSFQHDPE TSVLVLRKPG 
    INVASDWSIH LR

Genular Protein ID: 1991096994

Symbol: B4DIW2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 830
  • Mass: 93992
  • Checksum: 24441BB8EF36A400
  • Sequence:
  • MAAVAAVAAR RRRLSVSGRD ENSVELTMAE GPYKIILTAR PFRLDLLEDR SLLLSVNARG 
    LLEFEHQRAP RVSQGSKDPA EGDGAQPEET PRDGDKPEET QGKAEKDEPG AWEETFKTHS 
    DSKPYGPMSV GLDFSLPGME HVYGIPEHAD NLRLKVTEGG EPYRLYNLDV FQYELYNPMA 
    LYGSVPVLLA HNPHRDLGIF WLNAAETWVD ISSNTAGKTL FGKMMDYLQG SGETPQTDVR 
    WMSETGIIDV FLLLGPSISD VFRQYASLTG TQALPPLFSP GYHRSRWNYR DEADVLEVDQ 
    GFDDHNLPCD VIWLDIEHAD GKRYFTWDPS RFPQPRTMLE RLASKRRKLV AIVDPHIKVD 
    SGYRVHEELR NLGLYVKTRD GSDYEGWCWP GSAGYPDFTN PTMRAWWANM FSYDNYEGSA 
    PNLFVWNDMN EPSVFNGPEV TMLKDAQHYG GWEHRDVHNI YGLYVHMATA DGLRQRSGGM 
    ERPFVLARAF FAGSQRFGAV WTGDNTAEWD HLKISIPMCL SLGLVGLSFC GADVGGFFKN 
    PEPELLVRWY QMGAYQPFFR AHAHLDTGRR EPWLLPSQHN DIIRDALGQR YSLLPFWYTL 
    LYQAHREGIP VMRPLWVQYP QDVTTFNIDD QYLLGDALLV HPVSDSGAHG VQVYLPGQGE 
    VWYDIQSYQK HHGPQTLYLP VTLSSIPVFQ RGGTIVPRWM RVRRSSECMK DDPITLFVAL 
    SPQGTAQGEL FLDDGHTFNY QTRQEFLLRR FSFSGNTLVS SSADPEGHFE TPIWIERVVI 
    IGAGKPAAVV LQTKGSPESR LSFQHDPETS VLVLRKPGIN VASDWSIHLR

Genular Protein ID: 2759847224

Symbol: B4DSM6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 847
  • Mass: 96286
  • Checksum: F1E5DFA69B5EC85A
  • Sequence:
  • MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY KIILTARPFR 
    LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD GAQPEETPRD GDKPEETQGK 
    AEKDEPGAWE ETFKTHSDRK PYGPMSVGLD FSLPGMEHVY GIPEHADNLR LKVTEGGEPY 
    RLYNLDVFQY ELYNPMALYG SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK 
    MMDYLQGSGE TPQTDVRWMS ETGIIDVFLL LGPSISDVFR QYASLTGTQA LPPLFSLGYH 
    QSRWNYRDEA DVLEVDQGFD DHNLPCDVIW LDIEHADGKR YFTWDPSRFP QPRTMLERLA 
    SKRRKLVAIV DPHIKVDSGY RVHEELRNLG LYVKTRDGSD YEGWCWPGSA GYPDFTNPTM 
    RAWWANMFSY DNYEGSAPNL FVWNDMNEPS VFNGPEVTML KDAQHYGGWE HRDVHNIYGL 
    YVHMATADGL RQRSGGMERP FVLARAFFAG SQRFGAVWTG DNTAEWDHLK ISIPMCLSLG 
    LVGLSFCGAD VGGFFKNPEP ELLVRWYQMG AYQPFFRAHA HLDTGRREPW LLPSQHNDII 
    RDALGQRYSL LPFWYTLLYQ AHREGIPVMR PLWVQYPQDV TTFNIDDQYL LGDALLVHPV 
    SDSGAHGVQV YLPGQGEVWY DIQSYQKHHG PQTLYLPVTL SSIPVFQRGG TIVPRWMRVR 
    RSSECMKDDP ITLFVALSPQ GTAQGELFLD DGHTFNYQTR QEFLLRRFSF SGNTLVSSSA 
    DPEGHFETPI WIERVVIIGA GKPAAVVLQT KGSPESRLSF QHDPETSVLV LRKPGINVAS 
    DWSIHLR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.