Details for: MDN1

Gene ID: 23195

Symbol: MDN1

Ensembl ID: ENSG00000112159

Description: midasin AAA ATPase 1

Associated with

Other Information

Genular Protein ID: 2361616166

Symbol: MDN1_HUMAN

Name: Midasin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12102729

Title: Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein.

PubMed ID: 12102729

DOI: 10.1186/1471-2164-3-18

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22002106

Title: Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.

PubMed ID: 22002106

DOI: 10.1074/mcp.m111.013680

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26601951

Title: The crystal structure of the ubiquitin-like domain of ribosome assembly factor Ytm1 and characterization of its interaction with the AAA-ATPase Midasin.

PubMed ID: 26601951

DOI: 10.1074/jbc.m115.693259

PubMed ID: 27814492

Title: The AAA ATPase MDN1 acts as a SUMO-targeted regulator in mammalian pre-ribosome remodeling.

PubMed ID: 27814492

DOI: 10.1016/j.molcel.2016.09.039

Sequence Information:

  • Length: 5596
  • Mass: 632820
  • Checksum: 586C62616A1F96D4
  • Sequence:
  • MEHFLLEVAA APLRLIAAKN EKSRSELGRF LAKQVWTPQD RQCVLSTLAQ LLLDKDCTVL 
    VGRQLRPLLL DLLERNAEAI KAGGQINHDL HERLCVSMSK LIGNHPDVLP FALRYFKDTS 
    PVFQRLFLES SDANPVRYGR RRMKLRDLME AAFKFLQQEQ SVFRELWDWS VCVPLLRSHD 
    TLVRWYTANC LALVTCMNEE HKLSFLKKIF NSDELIHFRL RLLEEAQLQD LEKALVLANP 
    EVSLWRKQKE LQYLQGHLVS SDLSPRVTAV CGVVLPGQLP APGELGGNRS SSREQELALR 
    SYVLVESVCK SLQTLAMAVA SQNAVLLEGP IGCGKTSLVE YLAAVTGRTK PPQLLKVQLG 
    DQTDSKMLLG MYRCTDVPGE FVWQPGTLTQ AATMGHWILL EDIDYAPLDV VSVLIPLLEN 
    GELLIPGRGD CLKVAPGFQF FATRRLLSCG GNWYRPLNSH ATLLDKYWTK IHLDNLDKRE 
    LNEVLQSRYP SLLAVVDHLL DIYIQLTGEK HHSWSDSSVG CEQAPEEVSE ARRENKRPTL 
    EGRELSLRDL LNWCNRIAHS FDSSSLSASL NIFQEALDCF TAMLSEHTSK LKMAEVIGSK 
    LNISRKKAEF FCQLYKPEIV INELDLQVGR VRLLRKQSEA VHLQREKFTF AATRPSSVLI 
    EQLAVCVSKG EPVLLVGETG TGKTSTIQYL AHITGHRLRV VNMNQQSDTA DLLGGYKPVD 
    HKLIWLPLRE AFEELFAQTF SKKQNFTFLG HIQTCYRQKR WHDLLRLMQH VHKSAVNKDG 
    KDSETGLLIK EKWEAFGLRL NHAQQQMKMT ENTLLFAFVE GTLAQAVKKG EWILLDEINL 
    AAPEILECLS GLLEGSSGSL VLLDRGDTEP LVRHPDFRLF ACMNPATDVG KRNLPPGIRN 
    RFTELYVEEL ESKEDLQVLI VDYLKGLSVN KNTVQGIINF YTALRKESGT KLVDGTGHRP 
    HYSLRTLCRA LRFAASNPCG NIQRSLYEGF CLGFLTQLDR ASHPIVQKLI CQHIVPGNVK 
    SLLKQPIPEP KGGRLIQVEG YWIAVGDKEP TIDETYILTS SVKLNLRDIV RVVSAGTYPV 
    LIQGETSVGK TSLIQWLAAA TGNHCVRINN HEHTDIQEYI GCYTSDSSGK LVFKEGVLID 
    AMRKGYWIIL DELNLAPTDV LEALNRLLDD NRELLVTETQ EVVKAHPRFM LFATQNPPGL 
    YGGRKVLSRA FRNRFVELHF DELPSSELET ILHKRCSLPP SYCSKLVKVM LDLQSYRRSS 
    SVFAGKQGFI TLRDLFRWAE RYRLAEPTEK EYDWLQHLAN DGYMLLAGRV RKQEEIDVIQ 
    EVLEKHFKKK LCPQSLFSKE NVLKLLGKLS TQISTLECNF GHIVWTEGMR RLAMLVGRAL 
    EFGEPVLLVG DTGCGKTTIC QVFAALANQK LYSVSCHLHM ETSDFLGGLR PVRQKPNDKE 
    EIDTSRLFEW HDGPLVQAMK EDGFFLLDEI SLADDSVLER LNSVLEVEKS LVLAEKGSPE 
    DKDSEIELLT AGKKFRILAT MNPGGDFGKK ELSPALRNRF TEIWCPQSTS REDLIQIISH 
    NLRPGLCLGR IDPKGSDIPE VMLDFIDWLT HQEFGRKCVV SIRDILSWVN FMNKMGEEAA 
    LKRPEIISTV TSFVHAACLV YIDGIGSGVT SSGFGTALLA RKECLKFLIK RLAKIVRLTE 
    YQKNELKIYD RMKAKEFTGI DNLWGIHPFF IPRGPVLHRN NIADYALSAG TTAMNAQRLL 
    RATKLKKPIL LEGSPGVGKT SLVGALAKAS GNTLVRINLS EQTDITDLFG ADLPVEGGKG 
    GEFAWRDGPL LAALKAGHWV VLDELNLASQ SVLEGLNACF DHRGEIYVPE LGMSFQVQHE 
    KTKIFGCQNP FRQGGGRKGL PRSFLNRFTQ VFVDPLTVID MEFIASTLFP AIEKNIVKKM 
    VAFNNQIDHE VTVEKKWGQK GGPWEFNLRD LFRWCQLMLV DQSPGCYDPG QHVFLVYGER 
    MRTEEDKKKV IAVFKDVFGS NSNPYMGTRL FRITPYDVQL GYSVLSRGSC VPHPSRHPLL 
    LLHQSFQPLE SIMKCVQMSW MVILVGPASV GKTSLVQLLA HLTGHTLKIM AMNSAMDTTE 
    LLGGFEQVDL IRPWRRLLEK VEGTVRALLR DSLLISADDA EVVLRAWSHF LLTYKPKCLG 
    EGGKAITMEI VNKLEAVLLL MQRLNNKINS YCKAEFAKLV EEFRSFGVKL TQLASGHSHG 
    TFEWVDSMLV QALKSGDWLL MDNVNFCNPS VLDRLNALLE PGGVLTISER GMIDGSTPTI 
    TPNPNFRLFL SMDPVHGDIS RAMRNRGLEI YISGEGDAST PDNLDLKVLL HSLGLVGNSV 
    CDILLALHTE TRSTVVGSPT SSVSTLIQTA ILIVQYLQRG LSLDRAFSEA CWEVYVCSQH 
    SPANRKLVQA LLEKHVSSLR AHETWGDSIL GMGLWPDSVP SALFATEDSH LSTVRRDGQI 
    LVYCLNRMSM KTSSWTRSQP FTLQDLEKIM QSPSPENLKF NAVEVNTYWI DEPDVLVMAV 
    KLLIERATNQ DWMLRVKWLY HLAKNIPQGL ESIQIHLEAS AASLRNFYSH SLSGAVSNVF 
    KILQPNTTDE FVIPLDPRWN MQALDMIRNL MDFDPQTDQP DQLFALLESA ANKTIIYLDR 
    EKRVFTEANL VSVGSKKLRE SVLRMSFEFH QDPESYHTLP HEIVVNLAAF FELCDALVLL 
    WVQSSQGMVS DASANEILGS LRWRDRFWTV ADTVKVDAPG LALLALHWHW VLKHLVHQIP 
    RLLMNYEDKY YKEVQTVSEH IQNCLGSQTG GFAGIKKLQK FLGRPFPFKD KLVVECFSQL 
    KVLNKVLAIR EQMSALGESG WQEDINRLQV VASQWTLKKS LLQAWGLILR ANILEDVSLD 
    ELKNFVHAQC LELKAKGLSL GFLEKKHDEA SSLSHPDLTS VIHLTRSVQL WPAMEYLAML 
    WRYKVTADFM AQACLRRCSK NQQPQINEEI SHLISFCLYH TPVTPQELRD LWSLLHHQKV 
    SPEEITSLWS ELFNSMFMSF WSSTVTTNPE YWLMWNPLPG MQQREAPKSV LDSTLKGPGN 
    LNRPIFSKCC FEVLTSSWRA SPWDVSGLPI LSSSHVTLGE WVERTQQLQD ISSMLWTNMA 
    ISSVAEFRRT DSQLQGQVLF RHLAGLAELL PESRRQEYMQ NCEQLLLGSS QAFQHVGQTL 
    GDMAGQEVLP KELLCQLLTS LHHFVGEGES KRSLPEPAQR GSLWVSLGLL QIQTWLPQAR 
    FDPAVKREYK LNYVKEELHQ LQCEWKTRNL SSQLQTGRDL EDEVVVSYSH PHVRLLRQRM 
    DRLDNLTCHL LKKQAFRPQL PAYESLVQEI HHYVTSIAKA PAVQDLLTRL LQALHIDGPR 
    SAQVAQSLLK EEASWQQSHH QFRKRLSEEY TFYPDAVSPL QASILQLQHG MRLVASELHT 
    SLHSSMVGAD RLGTLATALL AFPSVGPTFP TYYAHADTLC SVKSEEVLRG LGKLILKRSG 
    GKELEGKGQK ACPTREQLLM NALLYLRSHV LCKGELDQRA LQLFRHVCQE IISEWDEQER 
    IAQEKAEQES GLYRYRSRNS RTALSEEEEE EREFRKQFPL HEKDFADILV QPTLEENKGT 
    SDGQEEEAGT NPALLSQNSM QAVMLIHQQL CLNFARSLWY QQTLPPHEAK HYLSLFLSCY 
    QTGASLVTHF YPLMGVELND RLLGSQLLAC TLSHNTLFGE APSDLMVKPD GPYDFYQHPN 
    VPEARQCQPV LQGFSEAVSH LLQDWPEHPA LEQLLVVMDR IRSFPLSSPI SKFLNGLEIL 
    LAKAQDWEEN ASRALSLRKH LDLISQMIIR WRKLELNCWS MSLDNTMKRH TEKSTKHWFS 
    IYQMLEKHMQ EQTEEQEDDK QMTLMLLVST LQAFIEGSSL GEFHVRLQML LVFHCHVLLM 
    PQVEGKDSLC SVLWNLYHYY KQFFDRVQAK IVELRSPLEK ELKEFVKISK WNDVSFWSIK 
    QSVEKTHRTL FKFMKKFEAV LSEPCRSSLV ESDKEEQPDF LPRPTDGAAS ELSSIQNLNR 
    ALRETLLAQP AAGQATIPEW CQGAAPSGLE GELLRRLPKL RKRMRKMCLT FMKESPLPRL 
    VEGLDQFTGE VISSVSELQS LKVEPSAEKE KQRSEAKHIL MQKQRALSDL FKHLAKIGLS 
    YRKGLAWARS KNPQEMLHLH PLDLQSALSI VSSTQEADSR LLTEISSSWD GCQKYFYRSL 
    ARHARLNAAL ATPAKEMGMG NVERCRGFSA HLMKMLVRQR RSLTTLSEQW IILRNLLSCV 
    QEIHSRLMGP QAYPVAFPPQ DGVQQWTERL QHLAMQCQIL LEQLSWLLQC CPSVGPAPGH 
    GNVQVLGQPP GPCLEGPELS KGQLCGVVLD LIPSNLSYPS PIPGSQLPSG CRMRKQDHLW 
    QQSTTRLTEM LKTIKTVKAD VDKIRQQSCE TLFHSWKDFE VCSSALSCLS QVSVHLQGLE 
    SLFILPGMEV EQRDSQMALV ESLEYVRGEI SKAMADFTTW KTHLLTSDSQ GGNQMLDEGF 
    VEDFSEQMEI AIRAILCAIQ NLEERKNEKA EENTDQASPQ EDYAGFERLQ SGHLTKLLED 
    DFWADVSTLH VQKIISAISE LLERLKSYGE DGTAAKHLFF SQSCSLLVRL VPVLSSYSDL 
    VLFFLTMSLA THRSTAKLLS VLAQVFTELA QKGFCLPKEF MEDSAGEGAT EFHDYEGGGI 
    GEGEGMKDVS DQIGNEEQVE DTFQKGQEKD KEDPDSKSDI KGEDNAIEMS EDFDGKMHDG 
    ELEEQEEDDE KSDSEGGDLD KHMGDLNGEE ADKLDERLWG DDDEEEDEEE EDNKTEETGP 
    GMDEEDSELV AKDDNLDSGN SNKDKSQQDK KEEKEEAEAD DGGQGEDKIN EQIDERDYDE 
    NEVDPYHGNQ EKVPEPEALD LPDDLNLDSE DKNGGEDTDN EEGEEENPLE IKEKPEEAGH 
    EAEERGETET DQNESQSPQE PEEGPSEDDK AEGEEEMDTG ADDQDGDAAQ HPEEHSEEQQ 
    QSVEEKDKEA DEEGGENGPA DQGFQPQEEE EREDSDTEEQ VPEALERKEH ASCGQTGVEN 
    MQNTQAMELA GAAPEKEQGK EEHGSGAADA NQAEGHESNF IAQLASQKHT RKNTQSFKRK 
    PGQADNERSM GDHNERVHKR LRTVDTDSHA EQGPAQQPQA QVEDADAFEH IKQGSDAYDA 
    QTYDVASKEQ QQSAKDSGKD QEEEEIEDTL MDTEEQEEFK AADVEQLKPE EIKSGTTAPL 
    GFDEMEVEIQ TVKTEEDQDP RTDKAHKETE NEKPERSRES TIHTAHQFLM DTIFQPFLKD 
    VNELRQELER QLEMWQPRES GNPEEEKVAA EMWQSYLILT APLSQRLCEE LRLILEPTQA 
    AKLKGDYRTG KRLNIRKVIP YIASQFRKDK IWLRRTKPSK RQYQICLAID DSSSMVDNHT 
    KQLAFESLAV IGNALTLLEV GQIAVCSFGE SVKLLHPFHE QFSDYSGSQI LRLCKFQQKK 
    TKIAQFLESV ANMFAAAQQL SQNISSETAQ LLLVVSDGRG LFLEGKERVL AAVQAARNAN 
    IFVIFVVLDN PSSRDSILDI KVPIFKGPGE MPEIRSYMEE FPFPYYIILR DVNALPETLS 
    DALRQWFELV TASDHP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.