Details for: FAF2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.59
Marker Score: 6,664 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.47
Marker Score: 15,141 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.46
Marker Score: 53,784 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.44
Marker Score: 88,634 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.42
Marker Score: 25,136 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.41
Marker Score: 13,384 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.39
Marker Score: 29,743 - Cell Name: neuron (CL0000540)
Fold Change: 1.39
Marker Score: 5,653 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.38
Marker Score: 20,632 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.38
Marker Score: 807 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.36
Marker Score: 12,771 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.36
Marker Score: 11,648 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.35
Marker Score: 1,496 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.35
Marker Score: 51,346 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.34
Marker Score: 2,951 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.33
Marker Score: 5,140 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.32
Marker Score: 1,600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.31
Marker Score: 26,122 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.3
Marker Score: 9,972 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.3
Marker Score: 2,004 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.27
Marker Score: 5,280 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.23
Marker Score: 1,652 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.22
Marker Score: 4,708 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.21
Marker Score: 1,784 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.21
Marker Score: 4,475 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.19
Marker Score: 692 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.18
Marker Score: 1,475 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.16
Marker Score: 487 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.15
Marker Score: 1,324 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.14
Marker Score: 630 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.11
Marker Score: 1,591 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.1
Marker Score: 743 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.09
Marker Score: 1,175 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.07
Marker Score: 2,058 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.07
Marker Score: 924 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.07
Marker Score: 312 - Cell Name: plasmablast (CL0000980)
Fold Change: 1.06
Marker Score: 1,415 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.06
Marker Score: 23,723 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.06
Marker Score: 427 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.04
Marker Score: 329 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.04
Marker Score: 2,368 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.04
Marker Score: 11,696 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.04
Marker Score: 504 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.03
Marker Score: 1,083 - Cell Name: basal cell (CL0000646)
Fold Change: 1.03
Marker Score: 1,325 - Cell Name: fat cell (CL0000136)
Fold Change: 1.01
Marker Score: 562 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1
Marker Score: 571 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,652 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,876 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.98
Marker Score: 4,100 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.98
Marker Score: 1,059 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,381 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.97
Marker Score: 4,063 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.97
Marker Score: 265 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.97
Marker Score: 1,170 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.97
Marker Score: 3,433 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.96
Marker Score: 15,054 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.95
Marker Score: 270 - Cell Name: Unknown (CL0002371)
Fold Change: 0.95
Marker Score: 1,011 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,389 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.94
Marker Score: 860 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.93
Marker Score: 719 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.93
Marker Score: 485 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.93
Marker Score: 14,894 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 477 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.92
Marker Score: 292 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 433 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.92
Marker Score: 482 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.91
Marker Score: 224 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.91
Marker Score: 941 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.91
Marker Score: 1,471 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,710 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.9
Marker Score: 3,554 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.9
Marker Score: 207 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.9
Marker Score: 259 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.9
Marker Score: 31,104 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5,105 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.89
Marker Score: 2,428 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.89
Marker Score: 609 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.89
Marker Score: 256 - Cell Name: club cell (CL0000158)
Fold Change: 0.88
Marker Score: 1,031 - Cell Name: podocyte (CL0000653)
Fold Change: 0.88
Marker Score: 326 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.88
Marker Score: 1,828 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.87
Marker Score: 758 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.87
Marker Score: 552 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,293 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.87
Marker Score: 4,018 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.86
Marker Score: 5,558 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.86
Marker Score: 322 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 309 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.86
Marker Score: 1,561 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.85
Marker Score: 1,209 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.85
Marker Score: 346 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.85
Marker Score: 8,557 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.85
Marker Score: 565 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.84
Marker Score: 506 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.84
Marker Score: 414 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.84
Marker Score: 523 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.83
Marker Score: 5,428 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.83
Marker Score: 3,592
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3427392295
Symbol: FAF2_HUMAN
Name: FAS-associated factor 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12372427
Title: Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.
PubMed ID: 12372427
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 18711132
Title: SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.
PubMed ID: 18711132
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19773358
Title: Targeting sequences of UBXD8 and AAM-B reveal that the ER has a direct role in the emergence and regression of lipid droplets.
PubMed ID: 19773358
DOI: 10.1242/jcs.054700
PubMed ID: 19818707
Title: The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER.
PubMed ID: 19818707
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23297223
Title: Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.
PubMed ID: 23297223
PubMed ID: 24160817
Title: Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex.
PubMed ID: 24160817
DOI: 10.1042/bj20130710
PubMed ID: 24215460
Title: Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
PubMed ID: 24215460
DOI: 10.1111/jnc.12606
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26692333
Title: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
PubMed ID: 26692333
DOI: 10.1038/nm.4013
PubMed ID: 31073040
Title: LMBR1L regulates lymphopoiesis through Wnt/beta-catenin signaling.
PubMed ID: 31073040
PubMed ID: 34739333
Title: Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.
PubMed ID: 34739333
Sequence Information:
- Length: 445
- Mass: 52623
- Checksum: D5510BCB0623096B
- Sequence:
MAAPEERDLT QEQTEKLLQF QDLTGIESMD QCRHTLEQHN WNIEAAVQDR LNEQEGVPSV FNPPPSRPLQ VNTADHRIYS YVVSRPQPRG LLGWGYYLIM LPFRFTYYTI LDIFRFALRF IRPDPRSRVT DPVGDIVSFM HSFEEKYGRA HPVFYQGTYS QALNDAKREL RFLLVYLHGD DHQDSDEFCR NTLCAPEVIS LINTRMLFWA CSTNKPEGYR VSQALRENTY PFLAMIMLKD RRMTVVGRLE GLIQPDDLIN QLTFIMDANQ TYLVSERLER EERNQTQVLR QQQDEAYLAS LRADQEKERK KREERERKRR KEEEVQQQKL AEERRRQNLQ EEKERKLECL PPEPSPDDPE SVKIIFKLPN DSRVERRFHF SQSLTVIHDF LFSLKESPEK FQIEANFPRR VLPCIPSEEW PNPPTLQEAG LSHTEVLFVQ DLTDE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.