Details for: PMPCA
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: neural progenitor cell (CL0011020)
Fold Change: 3.42
Marker Score: 13,232 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.71
Marker Score: 6,732 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.47
Marker Score: 994 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.27
Marker Score: 1,823 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.15
Marker Score: 1,446 - Cell Name: Leydig cell (CL0000178)
Fold Change: 1.11
Marker Score: 1,198 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.09
Marker Score: 1,158 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.09
Marker Score: 2,283 - Cell Name: Unknown (CL0002371)
Fold Change: 1.08
Marker Score: 1,149 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.04
Marker Score: 3,860 - Cell Name: pro-T cell (CL0000827)
Fold Change: 1.03
Marker Score: 4,235 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.01
Marker Score: 675 - Cell Name: osteoclast (CL0000092)
Fold Change: 1
Marker Score: 499 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,675 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,899 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,388 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.98
Marker Score: 282 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.96
Marker Score: 1,634 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.95
Marker Score: 2,598 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.94
Marker Score: 32,724 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,393 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.93
Marker Score: 1,242 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 474 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 432 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.91
Marker Score: 684 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 0.91
Marker Score: 1,512 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.91
Marker Score: 502 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.91
Marker Score: 3,931 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.91
Marker Score: 9,197 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5,177 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.91
Marker Score: 1,333 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.9
Marker Score: 909 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,688 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.87
Marker Score: 205 - Cell Name: stem cell (CL0000034)
Fold Change: 0.87
Marker Score: 2,076 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,290 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.84
Marker Score: 533 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.82
Marker Score: 518 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.81
Marker Score: 5,292 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.8
Marker Score: 549 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.8
Marker Score: 8,057 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.8
Marker Score: 2,176 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.8
Marker Score: 275 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.79
Marker Score: 315 - Cell Name: blood cell (CL0000081)
Fold Change: 0.78
Marker Score: 9,054 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.78
Marker Score: 6,710 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,263 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.78
Marker Score: 1,640 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 0.78
Marker Score: 249 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.77
Marker Score: 5,756 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.77
Marker Score: 2,283 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.77
Marker Score: 10,117 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.76
Marker Score: 1,742 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.76
Marker Score: 700 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 581 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.76
Marker Score: 215 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.76
Marker Score: 1,170 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.75
Marker Score: 1,887 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.75
Marker Score: 8,409 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.74
Marker Score: 308 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.74
Marker Score: 1,812 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.74
Marker Score: 787 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.73
Marker Score: 691 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.73
Marker Score: 654 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.73
Marker Score: 1,029 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.73
Marker Score: 1,948 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.73
Marker Score: 684 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.72
Marker Score: 460 - Cell Name: epithelial cell (CL0000066)
Fold Change: 0.72
Marker Score: 1,139 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.71
Marker Score: 370 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.71
Marker Score: 1,171 - Cell Name: basal cell (CL0000646)
Fold Change: 0.71
Marker Score: 921 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.71
Marker Score: 7,353 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.71
Marker Score: 289 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.71
Marker Score: 705 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.71
Marker Score: 2,723 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.71
Marker Score: 1,086 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.7
Marker Score: 138 - Cell Name: Unknown (CL0000548)
Fold Change: 0.7
Marker Score: 512 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.7
Marker Score: 185 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.68
Marker Score: 314 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 175 - Cell Name: enterocyte (CL0000584)
Fold Change: 0.68
Marker Score: 3,275 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.68
Marker Score: 2,858 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.68
Marker Score: 708 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.68
Marker Score: 566 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.68
Marker Score: 237 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.68
Marker Score: 447 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.68
Marker Score: 4,320 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.68
Marker Score: 1,373 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.67
Marker Score: 451 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.67
Marker Score: 172 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.67
Marker Score: 161 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.67
Marker Score: 1,586 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 612 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.67
Marker Score: 752 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.67
Marker Score: 1,520 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.67
Marker Score: 403 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 0.67
Marker Score: 326
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1728765288
Symbol: MPPA_HUMAN
Name: Mitochondrial-processing peptidase subunit alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7788527
Title: Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 7788527
PubMed ID: 8590280
Title: Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 8590280
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11840567
Title: Cluster analysis of an extensive human breast cancer cell line protein expression map database.
PubMed ID: 11840567
DOI: 10.1002/1615-9861(200202)2:2<212::aid-prot212>3.0.co;2-h
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25808372
Title: PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia.
PubMed ID: 25808372
DOI: 10.1093/brain/awv057
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26657514
Title: Autosomal recessive cerebellar ataxia caused by a homozygous mutation in PMPCA.
PubMed ID: 26657514
DOI: 10.1093/brain/awv362
Sequence Information:
- Length: 525
- Mass: 58253
- Checksum: 2751E7FCDC864E3F
- Sequence:
MAAVVLAATR LLRGSGSWGC SRLRFGPPAY RRFSSGGAYP NIPLSSPLPG VPKPVFATVD GQEKFETKVT TLDNGLRVAS QNKFGQFCTV GILINSGSRY EAKYLSGIAH FLEKLAFSST ARFDSKDEIL LTLEKHGGIC DCQTSRDTTM YAVSADSKGL DTVVALLADV VLQPRLTDEE VEMTRMAVQF ELEDLNLRPD PEPLLTEMIH EAAYRENTVG LHRFCPTENV AKINREVLHS YLRNYYTPDR MVLAGVGVEH EHLVDCARKY LLGVQPAWGS AEAVDIDRSV AQYTGGIAKL ERDMSNVSLG PTPIPELTHI MVGLESCSFL EEDFIPFAVL NMMMGGGGSF SAGGPGKGMF SRLYLNVLNR HHWMYNATSY HHSYEDTGLL CIHASADPRQ VREMVEIITK EFILMGGTVD TVELERAKTQ LTSMLMMNLE SRPVIFEDVG RQVLATRSRK LPHELCTLIR NVKPEDVKRV ASKMLRGKPA VAALGDLTDL PTYEHIQTAL SSKDGRLPRT YRLFR
Genular Protein ID: 3317575788
Symbol: Q5SXN9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 563
- Mass: 61713
- Checksum: 9CF1F8014F6516D6
- Sequence:
MAAVVLAATR LLRGSGSWGC SRLRFGPPAY RRFSSGGAYP NIPLSSPLPG VPKPVFATVD GQEKFETKVT TLDNGLRVAS QNKFGQFCTV GILINSGSRY EAKYLSGIAH FLEKLAFSST ARFDSKDEIL LTLEKHGGIC DCQTSRDTTM YAVSADSKGL DTVVALLADV VLQPRLTDEE VEMTRMAVQF ELEDLNLRPD PEPLLTEMIH EAAYRENTVG LHRFCPTENV AKINREVLHS YLRNYYTPDR MVLAGVGVEH EHLVDCARKY LLGVQPAWGS AEAVDIDRSV AQYTGGIAKL ERDMSNVSLG PTPIPELTHI MVGLESCSFL EEDFIPFAVL NMMMGGGGSF SAGGPGKGMF SRLYLNVLNR HHWMYNATSY HHSYEDTGLL CIHASADPRQ VREMVEIITK EFILMGGTVD TVELERAKTQ LTSMLMMNLE SRPVIFEDVG RQVLATRSRK LPHELCTLIR EYRRGSEGLP QASARLRGGR LALPQAVVGL WYVHHTQNLG PSPVVLSRGG QGQGRGVADL VSLPGPTMHL LPPWQVTPPS APLGGAVTTA QSC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.