SYT11 | ENSG00000132718 | NCBI 23208

Details for: SYT11

Gene ID: 23208

Symbol: SYT11

Ensembl ID: ENSG00000132718

Description: synaptotagmin 11

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-HSA-8856825)
Clathrin-mediated endocytosis
(R-HSA-8856828)
Membrane trafficking
(R-HSA-199991)
Vesicle-mediated transport
(R-HSA-5653656)
Autophagy
(GO:0006914)
Axon
(GO:0030424)
Beta-tubulin binding
(GO:0048487)
Calcium-dependent phospholipid binding
(GO:0005544)
Calcium ion-regulated exocytosis of neurotransmitter
(GO:0048791)
Calcium ion binding
(GO:0005509)
Calcium ion regulated lysosome exocytosis
(GO:1990927)
Cellular response to calcium ion
(GO:0071277)
Clathrin-coated vesicle membrane
(GO:0030665)
Clathrin binding
(GO:0030276)
Dendrite
(GO:0030425)
Dendritic spine
(GO:0043197)
Dopaminergic synapse
(GO:0098691)
Early phagosome
(GO:0032009)
Establishment of vesicle localization
(GO:0051650)
Excitatory synapse
(GO:0060076)
Exocytic vesicle
(GO:0070382)
Identical protein binding
(GO:0042802)
Inhibitory synapse
(GO:0060077)
Learning
(GO:0007612)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Memory
(GO:0007613)
Negative regulation of cytokine production
(GO:0001818)
Negative regulation of dopamine secretion
(GO:0033602)
Negative regulation of endocytosis
(GO:0045806)
Negative regulation of interleukin-6 production
(GO:0032715)
Negative regulation of microglial cell activation
(GO:1903979)
Negative regulation of neurotransmitter secretion
(GO:0046929)
Negative regulation of phagocytosis
(GO:0050765)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Neuron projection
(GO:0043005)
Perikaryon
(GO:0043204)
Phagocytic cup
(GO:0001891)
Phagocytic vesicle
(GO:0045335)
Phosphatidylserine binding
(GO:0001786)
Plasma membrane
(GO:0005886)
Plasma membrane repair
(GO:0001778)
Positive regulation of protein localization to phagocytic vesicle
(GO:1905171)
Postsynaptic density
(GO:0014069)
Presynapse
(GO:0098793)
Presynaptic active zone membrane
(GO:0048787)
Protein binding
(GO:0005515)
Recycling endosome
(GO:0055037)
Recycling endosome membrane
(GO:0055038)
Regulation of calcium ion-dependent exocytosis
(GO:0017158)
Regulation of defense response to bacterium
(GO:1900424)
Regulation of dopamine secretion
(GO:0014059)
Regulation of phagosome maturation
(GO:1905162)
Regulation of synaptic vesicle endocytosis
(GO:1900242)
Snare binding
(GO:0000149)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Trans-golgi network
(GO:0005802)
Translation initiation factor binding
(GO:0031369)
Ubiquitin protein ligase binding
(GO:0031625)
Vesicle
(GO:0031982)
Vesicle fusion
(GO:0006906)

Other Information

Proteins

Synaptotagmin XI

Genular Protein ID: 3684136100

Symbol: SYT11_HUMAN

Name: Synaptotagmin XI

UniProtKB Accession Codes:

Q9BT88 Q14998 Q5W0D4 Q68CT5 Q8IXU3 Q96SU2

Database IDs:

Citations:

PubMed ID: 7584044

Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7584044

DOI: 10.1093/dnares/1.5.223

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12925569

Title: The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI.

PubMed ID: 12925569

DOI: 10.1093/hmg/ddg269

PubMed ID: 27278822

Title: The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway.

PubMed ID: 27278822

DOI: 10.1038/ncomms11803

Sequence Information:

Length: 431
Mass: 48297
Checksum: 5C8667D2C23D758E
Sequence:

MAEITNIRPS FDVSPVVAGL IGASVLVVCV SVTVFVWSCC HQQAEKKQKN PPYKFIHMLK 
GISIYPETLS NKKKIIKVRR DKDGPGREGG RRNLLVDAAE AGLLSRDKDP RGPSSGSCID 
QLPIKMDYGE ELRSPITSLT PGESKTTSPS SPEEDVMLGS LTFSVDYNFP KKALVVTIQE 
AHGLPVMDDQ TQGSDPYIKM TILPDKRHRV KTRVLRKTLD PVFDETFTFY GIPYSQLQDL 
VLHFLVLSFD RFSRDDVIGE VMVPLAGVDP STGKVQLTRD IIKRNIQKCI SRGELQVSLS 
YQPVAQRMTV VVLKARHLPK MDITGLSGNP YVKVNVYYGR KRIAKKKTHV KKCTLNPIFN 
ESFIYDIPTD LLPDISIEFL VIDFDRTTKN EVVGRLILGA HSVTASGAEH WREVCESPRK 
PVAKWHSLSE Y

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SYT11

Associated with

Other Information

Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. PubMed ID: 7584044

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI. PubMed ID: 12925569

The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. PubMed ID: 27278822