Details for: JMJD6
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.75
Marker Score: 4,824 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.74
Marker Score: 1,854 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.66
Marker Score: 6,143 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.44
Marker Score: 49,006 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 1.41
Marker Score: 3,473 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 1.32
Marker Score: 1,113 - Cell Name: mature T cell (CL0002419)
Fold Change: 1.3
Marker Score: 12,902 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.28
Marker Score: 1,880 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.26
Marker Score: 3,535 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.19
Marker Score: 1,017 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 1.13
Marker Score: 1,561 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.13
Marker Score: 1,189 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 1.12
Marker Score: 644 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.08
Marker Score: 2,287 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.02
Marker Score: 15,986 - Cell Name: memory T cell (CL0000813)
Fold Change: 1
Marker Score: 432 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,637 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,859 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.99
Marker Score: 1,872 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,378 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.97
Marker Score: 1,394 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 0.97
Marker Score: 402 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.94
Marker Score: 539 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.94
Marker Score: 282 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 0.94
Marker Score: 318 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,379 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.94
Marker Score: 2,329 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 473 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 432 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,715 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.91
Marker Score: 614 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.88
Marker Score: 405 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.88
Marker Score: 219 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.88
Marker Score: 178 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.87
Marker Score: 1,545 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 0.87
Marker Score: 631 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.86
Marker Score: 8,747 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.86
Marker Score: 5,195 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.86
Marker Score: 1,074 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.86
Marker Score: 1,033 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.85
Marker Score: 2,087 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.85
Marker Score: 758 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.85
Marker Score: 777 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.85
Marker Score: 508 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.84
Marker Score: 201 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.84
Marker Score: 4,780 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.83
Marker Score: 827 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.83
Marker Score: 46,376 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.83
Marker Score: 256 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.82
Marker Score: 180 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.82
Marker Score: 209 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 0.81
Marker Score: 616 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.81
Marker Score: 2,206 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 0.81
Marker Score: 1,412 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 0.8
Marker Score: 365 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.8
Marker Score: 774 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.8
Marker Score: 258 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.8
Marker Score: 197 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 0.8
Marker Score: 199 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.8
Marker Score: 504 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8
Marker Score: 320 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 0.8
Marker Score: 326 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.8
Marker Score: 178 - Cell Name: leukocyte (CL0000738)
Fold Change: 0.8
Marker Score: 457 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.8
Marker Score: 366 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.79
Marker Score: 199 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.79
Marker Score: 481 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.78
Marker Score: 558 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.78
Marker Score: 3,837 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.78
Marker Score: 318 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.78
Marker Score: 349 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.78
Marker Score: 1,772 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,261 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 0.77
Marker Score: 2,260 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 591 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.77
Marker Score: 526 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.77
Marker Score: 577 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.77
Marker Score: 3,017 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.76
Marker Score: 648 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.76
Marker Score: 507 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.76
Marker Score: 776 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.76
Marker Score: 765 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.76
Marker Score: 827 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.76
Marker Score: 238 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.76
Marker Score: 1,009 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.76
Marker Score: 213 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.76
Marker Score: 2,385 - Cell Name: theca cell (CL0000503)
Fold Change: 0.75
Marker Score: 539 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 0.75
Marker Score: 160 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.75
Marker Score: 199 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.75
Marker Score: 1,648 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.75
Marker Score: 476 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.75
Marker Score: 591 - Cell Name: tracheobronchial goblet cell (CL0019003)
Fold Change: 0.75
Marker Score: 205 - Cell Name: mast cell (CL0000097)
Fold Change: 0.75
Marker Score: 432 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.74
Marker Score: 3,210 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.74
Marker Score: 748 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.74
Marker Score: 473 - Cell Name: T-helper 1 cell (CL0000545)
Fold Change: 0.74
Marker Score: 288
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 302083204
Symbol: JMJD6_HUMAN
Name: Histone arginine demethylase JMJD6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9628581
Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9628581
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14729065
Title: Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals.
PubMed ID: 14729065
PubMed ID: 15072554
Title: Phosphatidylserine receptor cooperates with high-density lipoprotein receptor in recognition of apoptotic cells by thymic nurse cells.
PubMed ID: 15072554
PubMed ID: 15622002
Title: Phosphatidylserine receptor in chronic pancreatitis: evidence for a macrophage independent role.
PubMed ID: 15622002
PubMed ID: 17947579
PubMed ID: 19574390
Title: Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.
PubMed ID: 19574390
PubMed ID: 21060799
Title: Analysis of Jmjd6 cellular localization and testing for its involvement in histone demethylation.
PubMed ID: 21060799
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21555454
Title: The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.
PubMed ID: 21555454
DOI: 10.1128/mcb.01341-10
PubMed ID: 22189873
Title: The hydroxylation activity of Jmjd6 is required for its homo-oligomerization.
PubMed ID: 22189873
DOI: 10.1002/jcb.24035
PubMed ID: 24360279
Title: Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release.
PubMed ID: 24360279
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24498420
Title: JMJD6 regulates ERalpha methylation on arginine.
PubMed ID: 24498420
PubMed ID: 20684070
Title: Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6.
PubMed ID: 20684070
PubMed ID: 20679243
Title: Interaction of JMJD6 with single-stranded RNA.
PubMed ID: 20679243
PubMed ID: 29176719
Title: Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
PubMed ID: 29176719
Sequence Information:
- Length: 403
- Mass: 46462
- Checksum: 9C9AADA98B24B035
- Sequence:
MNHKSKKRIR EAKRSARPEL KDSLDWTRHN YYESFSLSPA AVADNVERAD ALQLSVEEFV ERYERPYKPV VLLNAQEGWS AQEKWTLERL KRKYRNQKFK CGEDNDGYSV KMKMKYYIEY MESTRDDSPL YIFDSSYGEH PKRRKLLEDY KVPKFFTDDL FQYAGEKRRP PYRWFVMGPP RSGTGIHIDP LGTSAWNALV QGHKRWCLFP TSTPRELIKV TRDEGGNQQD EAITWFNVIY PRTQLPTWPP EFKPLEILQK PGETVFVPGG WWHVVLNLDT TIAITQNFAS STNFPVVWHK TVRGRPKLSR KWYRILKQEH PELAVLADSV DLQESTGIAS DSSSDSSSSS SSSSSDSDSE CESGSEGDGT VHRRKKRRTC SMVGNGDTTS QDDCVSKERS SSR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.