SULF1 | ENSG00000137573 | NCBI 23213

Details for: SULF1

Gene ID: 23213

Symbol: SULF1

Ensembl ID: ENSG00000137573

Description: sulfatase 1

Associated with

Apoptotic process
(GO:0006915)
Arylsulfatase activity
(GO:0004065)
Bone development
(GO:0060348)
Calcium ion binding
(GO:0005509)
Cartilage development
(GO:0051216)
Cell surface
(GO:0009986)
Chondrocyte development
(GO:0002063)
Collagen-containing extracellular matrix
(GO:0062023)
Embryonic skeletal system development
(GO:0048706)
Endoplasmic reticulum
(GO:0005783)
Esophagus smooth muscle contraction
(GO:0014846)
Extracellular space
(GO:0005615)
Glial cell-derived neurotrophic factor receptor signaling pathway
(GO:0035860)
Glomerular basement membrane development
(GO:0032836)
Glomerular filtration
(GO:0003094)
Glycosaminoglycan binding
(GO:0005539)
Golgi apparatus
(GO:0005794)
Golgi stack
(GO:0005795)
Heparan sulfate proteoglycan metabolic process
(GO:0030201)
Innervation
(GO:0060384)
Kidney development
(GO:0001822)
Membrane raft
(GO:0045121)
N-acetylglucosamine-6-sulfatase activity
(GO:0008449)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Negative regulation of fibroblast growth factor receptor signaling pathway
(GO:0040037)
Negative regulation of prostatic bud formation
(GO:0060686)
Plasma membrane
(GO:0005886)
Positive regulation of bmp signaling pathway
(GO:0030513)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Positive regulation of wnt signaling pathway
(GO:0030177)
Regulation of fibroblast growth factor receptor signaling pathway
(GO:0040036)
Vascular endothelial growth factor receptor signaling pathway
(GO:0048010)

Other Information

Proteins

Extracellular sulfatase Sulf-1

Genular Protein ID: 1812813888

Symbol: SULF1_HUMAN

Name: Extracellular sulfatase Sulf-1

UniProtKB Accession Codes:

Q8IWU6 Q86YV8 Q8NCA2 Q9UPS5

Database IDs:

Citations:

PubMed ID: 12368295

Title: Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

PubMed ID: 12368295

DOI: 10.1074/jbc.m205131200

PubMed ID: 12686563

Title: Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.

PubMed ID: 12686563

DOI: 10.1074/jbc.m302203200

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

Sequence Information:

Length: 871
Mass: 101027
Checksum: 9A90ADB280304364
Sequence:

MKYSCCALVL AVLGTELLGS LCSTVRSPRF RGRIQQERKN IRPNIILVLT DDQDVELGSL 
QVMNKTRKIM EHGGATFINA FVTTPMCCPS RSSMLTGKYV HNHNVYTNNE NCSSPSWQAM 
HEPRTFAVYL NNTGYRTAFF GKYLNEYNGS YIPPGWREWL GLIKNSRFYN YTVCRNGIKE 
KHGFDYAKDY FTDLITNESI NYFKMSKRMY PHRPVMMVIS HAAPHGPEDS APQFSKLYPN 
ASQHITPSYN YAPNMDKHWI MQYTGPMLPI HMEFTNILQR KRLQTLMSVD DSVERLYNML 
VETGELENTY IIYTADHGYH IGQFGLVKGK SMPYDFDIRV PFFIRGPSVE PGSIVPQIVL 
NIDLAPTILD IAGLDTPPDV DGKSVLKLLD PEKPGNRFRT NKKAKIWRDT FLVERGKFLR 
KKEESSKNIQ QSNHLPKYER VKELCQQARY QTACEQPGQK WQCIEDTSGK LRIHKCKGPS 
DLLTVRQSTR NLYARGFHDK DKECSCRESG YRASRSQRKS QRQFLRNQGT PKYKPRFVHT 
RQTRSLSVEF EGEIYDINLE EEEELQVLQP RNIAKRHDEG HKGPRDLQAS SGGNRGRMLA 
DSSNAVGPPT TVRVTHKCFI LPNDSIHCER ELYQSARAWK DHKAYIDKEI EALQDKIKNL 
REVRGHLKRR KPEECSCSKQ SYYNKEKGVK KQEKLKSHLH PFKEAAQEVD SKLQLFKENN 
RRRKKERKEK RRQRKGEECS LPGLTCFTHD NNHWQTAPFW NLGSFCACTS SNNNTYWCLR 
TVNETHNFLF CEFATGFLEY FDMNTDPYQL TNTVHTVERG ILNQLHVQLM ELRSCQGYKQ 
CNPRPKNLDV GNKDGGSYDL HRGQLWDGWE G

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SULF1

Associated with

Other Information

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. PubMed ID: 12368295

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer. PubMed ID: 12686563

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. PubMed ID: 10470851