Details for: TBC1D1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 3.75
Marker Score: 3,576 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.02
Marker Score: 6,625 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 2.99
Marker Score: 1,575 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.9
Marker Score: 1,572 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.86
Marker Score: 2,206 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.75
Marker Score: 6,897 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.74
Marker Score: 11,481 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.71
Marker Score: 792 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.66
Marker Score: 2,301 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.43
Marker Score: 54,338 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.27
Marker Score: 717 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.19
Marker Score: 73,929 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.15
Marker Score: 1,071 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.12
Marker Score: 6,034 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.11
Marker Score: 2,423 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.08
Marker Score: 3,995 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.07
Marker Score: 44,178 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.02
Marker Score: 19,042 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 2.02
Marker Score: 3,342 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.89
Marker Score: 116,358 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.88
Marker Score: 71,371 - Cell Name: podocyte (CL0000653)
Fold Change: 1.8
Marker Score: 665 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.8
Marker Score: 15,424 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.79
Marker Score: 562 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.78
Marker Score: 6,314 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.78
Marker Score: 1,060 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.72
Marker Score: 16,329 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.7
Marker Score: 25,402 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 1.69
Marker Score: 1,205 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.68
Marker Score: 533 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 1.67
Marker Score: 2,180 - Cell Name: IgG plasmablast (CL0000982)
Fold Change: 1.67
Marker Score: 460 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.66
Marker Score: 61,400 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.64
Marker Score: 2,750 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.62
Marker Score: 1,747 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.61
Marker Score: 2,369 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.58
Marker Score: 510 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.56
Marker Score: 568 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.56
Marker Score: 3,665 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.55
Marker Score: 560 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 1.53
Marker Score: 580 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 1.52
Marker Score: 3,830 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.47
Marker Score: 2,760 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.45
Marker Score: 1,256 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.45
Marker Score: 493 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.44
Marker Score: 2,086 - Cell Name: neuron (CL0000540)
Fold Change: 1.37
Marker Score: 5,560 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.33
Marker Score: 4,712 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.32
Marker Score: 740 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.32
Marker Score: 336 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.32
Marker Score: 20,640 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.31
Marker Score: 264 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.3
Marker Score: 13,214 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.3
Marker Score: 25,886 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.3
Marker Score: 3,474 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 1.27
Marker Score: 3,640 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.25
Marker Score: 4,850 - Cell Name: pulmonary ionocyte (CL0017000)
Fold Change: 1.25
Marker Score: 769 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.25
Marker Score: 9,599 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.24
Marker Score: 1,762 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.23
Marker Score: 1,899 - Cell Name: IgA plasmablast (CL0000984)
Fold Change: 1.23
Marker Score: 322 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.22
Marker Score: 1,150 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.21
Marker Score: 2,468 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.21
Marker Score: 852 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.19
Marker Score: 1,211 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.18
Marker Score: 707 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.17
Marker Score: 2,751 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.16
Marker Score: 806 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 1.15
Marker Score: 755 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.14
Marker Score: 1,020 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.11
Marker Score: 321 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.09
Marker Score: 60,875 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.09
Marker Score: 2,953 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 1.08
Marker Score: 1,886 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.08
Marker Score: 1,141 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.07
Marker Score: 2,662 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.07
Marker Score: 1,052 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.05
Marker Score: 969 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.05
Marker Score: 1,317 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 1.05
Marker Score: 480 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 1.04
Marker Score: 1,042 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 1.04
Marker Score: 359 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 1.04
Marker Score: 269 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.03
Marker Score: 6,614 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.02
Marker Score: 3,040 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.02
Marker Score: 4,700 - Cell Name: pericyte (CL0000669)
Fold Change: 1.02
Marker Score: 593 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 1.01
Marker Score: 1,968 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1
Marker Score: 374 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 1
Marker Score: 223 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,610 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,833 - Cell Name: Unknown (CL0000548)
Fold Change: 0.99
Marker Score: 718 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,378 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.97
Marker Score: 367 - Cell Name: centroblast (CL0009112)
Fold Change: 0.97
Marker Score: 477 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 0.96
Marker Score: 2,325 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.96
Marker Score: 432 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.96
Marker Score: 230
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1378031667
Symbol: TBCD1_HUMAN
Name: TBC1 domain family member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10470851
Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10470851
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 24879834
Title: The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle.
PubMed ID: 24879834
DOI: 10.2337/db14-0337
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 21454505
Title: Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
PubMed ID: 21454505
PubMed ID: 16893906
Title: TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition.
PubMed ID: 16893906
DOI: 10.1093/hmg/ddl204
PubMed ID: 18325908
Title: R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population.
PubMed ID: 18325908
DOI: 10.1093/hmg/ddn070
Sequence Information:
- Length: 1168
- Mass: 133084
- Checksum: 5EFEA168F04C88E0
- Sequence:
MEPITFTARK HLLSNEVSVD FGLQLVGSLP VHSLTTMPML PWVVAEVRRL SRQSTRKEPV TKQVRLCVSP SGLRCEPEPG RSQQWDPLIY SSIFECKPQR VHKLIHNSHD PSYFACLIKE DAVHRQSICY VFKADDQTKV PEIISSIRQA GKIARQEELH CPSEFDDTFS KKFEVLFCGR VTVAHKKAPP ALIDECIEKF NHVSGSRGSE SPRPNPPHAA PTGSQEPVRR PMRKSFSQPG LRSLAFRKEL QDGGLRSSGF FSSFEESDIE NHLISGHNIV QPTDIEENRT MLFTIGQSEV YLISPDTKKI ALEKNFKEIS FCSQGIRHVD HFGFICRESS GGGGFHFVCY VFQCTNEALV DEIMMTLKQA FTVAAVQQTA KAPAQLCEGC PLQSLHKLCE RIEGMNSSKT KLELQKHLTT LTNQEQATIF EEVQKLRPRN EQRENELIIS FLRCLYEEKQ KEHIHIGEMK QTSQMAAENI GSELPPSATR FRLDMLKNKA KRSLTESLES ILSRGNKARG LQEHSISVDL DSSLSSTLSN TSKEPSVCEK EALPISESSF KLLGSSEDLS SDSESHLPEE PAPLSPQQAF RRRANTLSHF PIECQEPPQP ARGSPGVSQR KLMRYHSVST ETPHERKDFE SKANHLGDSG GTPVKTRRHS WRQQIFLRVA TPQKACDSSS RYEDYSELGE LPPRSPLEPV CEDGPFGPPP EEKKRTSREL RELWQKAILQ QILLLRMEKE NQKLQASEND LLNKRLKLDY EEITPCLKEV TTVWEKMLST PGRSKIKFDM EKMHSAVGQG VPRHHRGEIW KFLAEQFHLK HQFPSKQQPK DVPYKELLKQ LTSQQHAILI DLGRTFPTHP YFSAQLGAGQ LSLYNILKAY SLLDQEVGYC QGLSFVAGIL LLHMSEEEAF KMLKFLMFDM GLRKQYRPDM IILQIQMYQL SRLLHDYHRD LYNHLEEHEI GPSLYAAPWF LTMFASQFPL GFVARVFDMI FLQGTEVIFK VALSLLGSHK PLILQHENLE TIVDFIKSTL PNLGLVQMEK TINQVFEMDI AKQLQAYEVE YHVLQEELID SSPLSDNQRM DKLEKTNSSL RKQNLDLLEQ LQVANGRIQS LEATIEKLLS SESKLKQAML TLELERSALL QTVEELRRRS AEPSDREPEC TQPEPTGD
Genular Protein ID: 1886201485
Symbol: Q6PJJ8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 900
- Mass: 102877
- Checksum: 2685321241656FC7
- Sequence:
IENHLISGHN IVQPTDIEEN RTMLFTIGQS EVYLISPDTK KIALEKNFKE ISFCSQGIRH VDHFGFICRE SSGGGGFHFV CYVFQCTNEA LVDEIMMTLK QAFTVAAVQQ TAKAPAQLCE GCPLQSLHKL CERIEGMNSS KTKLELQKHL TTLTNQEQAT IFEEVQKLRP RNEQRENELI ISFLRCLYEE KQKEHIHIGE MKQTSQMAAE NIGSELPPSA TRFRLDMLKN KAKRSLTESL ESILSRGNKA RGLQEHSISV DLDSSLSSTL SNTSKEPSVC EKEALPISES SFKLLGSSED LSSDSESHLP EEPAPLSPQQ AFRRRANTLS HFPIECQEPP QPARGSPGVS QRKLMRYHSV STETPHERKD FESKANHLGD SGGTPVKTRR HSWRQQIFLR VATPQKACDS SSRYEDYSEL GELPPRSPLE PVCEDGPFGP PPEEKKRTSR ELRELWQKAI LQQILLLRME KENQKLQASE NDLLNKRLKL DYEEITPCLK EVTTVWEKML STPGRSKIKF DMEKMHSAVG QGVPRHHRGE IWKFLAEQFH LKHQFPSKQQ PKDVPYKELL KQLTSQQHAI LIDLGRTFPT HPYFSAQLGA GQLSLYNILK AYSLLDQEVG YCQGLSFVAG ILLLHMSEEE AFKMLKFLMF DMGLRKQYRP DMIILQIQMY QLSRLLHDYH RDLYNHLEEH EIGPSLYAAP WFLTMFASQF PLGFVARVFD MIFLQGTEVI FKVALSLLGS HKPLILQHEN LETIVDFIKS TLPNLGLVQM EKTINQVFEM DIAKQLQAYE VEYHVLQEEL IDSSPLSDNQ RMDKLEKTNS SLRKQNLDLL EQLQVANGRI QSLEATIEKL LSSESKLKQA MLTLELERSA LLQTVEELRR RSAEPSDREP ECTQPEPTGD
Genular Protein ID: 244377354
Symbol: Q8NC59_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16303743
Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
PubMed ID: 16303743
Sequence Information:
- Length: 265
- Mass: 30804
- Checksum: 156483811A194610
- Sequence:
MSEEEAFKML KFLMFDMGLR KQYRPDMIIL QIQMYQLSRL LHDYHRDLYN HLEEHEIGPS LYAAPWFLTM FASQFPLGFV ARVFDMIFLQ GTEVIFKVAL SLLGSHKPLI LQHENLETIV DFIKSTLPNL GLVQMEKTIN QVFEMDIAKQ LQAYEVEYHV LQEELIDSSP LSDNQRMDKL EKTNSSLRKQ NLDLLEQLQV ANGRIQSLEA TIEKLLSSES KLKQAMLTLE LERSALLQTV EELRRRSAEP SDREPECTQP EPTGD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.