Details for: NBEAL2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.58
Marker Score: 1,748 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.2
Marker Score: 799 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.15
Marker Score: 1,197 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.15
Marker Score: 17,936 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 1.1
Marker Score: 1,325 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.07
Marker Score: 1,212 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.06
Marker Score: 637 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.03
Marker Score: 1,088 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,752 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1
Marker Score: 321 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,977 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,401 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.96
Marker Score: 6,145 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.96
Marker Score: 300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,403 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 485 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 440 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.92
Marker Score: 51,298 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,713 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.9
Marker Score: 1,324 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.89
Marker Score: 608 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.89
Marker Score: 1,808 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.88
Marker Score: 2,065 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.87
Marker Score: 4,961 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,249 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 308 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.84
Marker Score: 7,240 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.77
Marker Score: 1,945 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 589 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.74
Marker Score: 622 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 376 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.71
Marker Score: 286 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.7
Marker Score: 305 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.69
Marker Score: 973 - Cell Name: brush cell (CL0002204)
Fold Change: 0.68
Marker Score: 620 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.68
Marker Score: 273 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.67
Marker Score: 322 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.67
Marker Score: 710 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 0.66
Marker Score: 1,096 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.64
Marker Score: 130 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.64
Marker Score: 2,676 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 0.63
Marker Score: 4,919 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.63
Marker Score: 1,677 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.62
Marker Score: 341 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.62
Marker Score: 289 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.62
Marker Score: 9,909 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.61
Marker Score: 1,507 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.6
Marker Score: 1,177 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.6
Marker Score: 258 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.59
Marker Score: 1,348 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.58
Marker Score: 175 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.56
Marker Score: 144 - Cell Name: myelocyte (CL0002193)
Fold Change: 0.55
Marker Score: 236 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.54
Marker Score: 203 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.54
Marker Score: 418 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 431 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.54
Marker Score: 1,856 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.54
Marker Score: 354 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.54
Marker Score: 240 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.53
Marker Score: 153 - Cell Name: Unknown (CL0000548)
Fold Change: 0.53
Marker Score: 386 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.53
Marker Score: 316 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.53
Marker Score: 131 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.53
Marker Score: 1,665 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 0.53
Marker Score: 463 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.52
Marker Score: 271 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.52
Marker Score: 530 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.52
Marker Score: 331 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 0.51
Marker Score: 474 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.5
Marker Score: 190 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.5
Marker Score: 188 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.5
Marker Score: 1,235 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.5
Marker Score: 426 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.5
Marker Score: 1,385 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.5
Marker Score: 221 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.5
Marker Score: 2,073 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.49
Marker Score: 343 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.49
Marker Score: 1,377 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.49
Marker Score: 480 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.49
Marker Score: 169 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.49
Marker Score: 590 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.47
Marker Score: 591 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.47
Marker Score: 503 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 0.47
Marker Score: 1,464 - Cell Name: intermediate monocyte (CL0002393)
Fold Change: 0.46
Marker Score: 158 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.46
Marker Score: 430 - Cell Name: basal cell (CL0000646)
Fold Change: 0.46
Marker Score: 589 - Cell Name: stem cell (CL0000034)
Fold Change: 0.45
Marker Score: 1,080 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.45
Marker Score: 131 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.45
Marker Score: 4,559 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.45
Marker Score: 481 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.44
Marker Score: 374 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.44
Marker Score: 3,298 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.44
Marker Score: 256 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.44
Marker Score: 98 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.44
Marker Score: 136 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.43
Marker Score: 113 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.43
Marker Score: 192
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3975212332
Symbol: NBEL2_HUMAN
Name: Neurobeachin-like protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 9628581
Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9628581
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21765412
Title: NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet alpha-granules.
PubMed ID: 21765412
DOI: 10.1038/ng.883
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21765411
Title: Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome.
PubMed ID: 21765411
DOI: 10.1038/ng.885
PubMed ID: 21765413
Title: Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome.
PubMed ID: 21765413
DOI: 10.1038/ng.884
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 2754
- Mass: 302517
- Checksum: D3DA8DBDF9BB11CC
- Sequence:
MAASERLYEL WLLYYAQKDL GYLQQWLKAF VGAFKKSISL SSLEPRRPEE AGAEVPLLPL DELHVLAEQL HQADLEQALL LLKLFIILCR NLENIEAGRG QVLVPRVLAL LTKLVAELKG CPPPQGRGTQ LENVALHALL LCEGLFDPYQ TWRRQRSGEV ISSKEKSKYK FPPAALPQEF SAFFQESLQN ADHLPPILLL RLIHLFCAVL AGGKENGQMA VSDGSVKGLL SVVRGWSRGP APDPCLVPLA LEALVGAVHV LHASRAPPRG PELRALLESY FHVLNADWPA GLSSGPEEAL VTLRVSMLDA IPMMLACEDR PVLQATFLSN NCFEHLTRLI QNSKLYLQSR APPEGDSDLA TRLLTEPDVQ KVLDQDTDAI AVHVVRVLTC IMSDSPSAKE VFKERIGYPH LQEVLQSHGP PTHRLLQELL NMAVEGDHSM CPPPPIRNEQ PVLVLAQWLP SLPTAELRLF LAQRLRWLCD SCPASRATCV QAGLVGCLLE TLSTGLALEA RCQEQLLALL QALGRVSIRP MELRHLLRPR PGLDSEPGGA EAGKARHAGA VIRTLSGMAR HQGPARALRY FDLTPSMAGI MVPPVQRWPG PGFTFHAWLC LHPMDTAPTP APTRPLQRKQ LYSFFTSSGS GFEAFFTAAG TLVVAVCTRK EYLTMSLPEV SFADSAWHCV AIVHVPGRRP FSQNLVHVYK DGHLVKTAPL RCPSLSEPFS SCCIGSAGYR TTTTTTGLPT PPVPATLAYT HPALTRSQSV PASTGLGWGS GLVAPLQEGS IDSTLAGTQD TRWGSPTSLE GELGAVAIFH EALQATALRT LCTLGPNETA PFKPEGELHE LSTRLLLHYS PQACKNNICL DLSPSHGLDG RLTGHRVETW DVKDVVNCVG GMGALLPLLE RVAAQPKEAE AGPAETHDLV GPELTSGHNT QGLVLPLGKS SEERMERNAV AAFLLMLRNF LQGHMVNQES LVQCQGPAII GALLRKVPSW AMDMNVLMSA QLLMEQVAAE GSGPLLYLLY QHLLFNFHLW TLSDFAVRLG HIQYMSSIVR EHRQKLRKKY GVQFILDALR THYSPQRERP LAADDLRTVQ TSLLGLAREF LVRSLSADDV QVTQTMLSFL AATGDDGQAV GALDLLLALL HGSLVQESLA VFLLEPGNLE VLLALLVRPG SLPLLPDRVC KILRRLQQNE RLPERSRQRL RLRECGLQGL VACLPEGTVS PQLCQGLYKL FLGADCLNLS DLLAVVQLSL QADLSVRLDI CRQLFHLIYG QPDVVRLLAR QAGWQDVLTR LYVLEAATAG SPPPSSPESP TSPKPAPPKP PTESPAEPSD VFLPSEAPCP DPDGFYHALS PFCTPFDLGL ERSSVGSGNT AGGGGSSGTL TPASQPGTPS PLDGPRPFPA APGRHSSSLS NVLEDGSLPE PTISGDDTSN TSNPQQTSEE ELCNLLTNVL FSVTWRGVEG SDEAAWRERG QVFSVLTQLG ASATLVRPPD CIKRSLLEMM LESALTDIKE APVGVLASLT QQALWLLRLL QDFLCAEGHG NQELWSEKLF EGVCSLLDRL GAWPHLANGT ADLREMAQIG LRLVLGYILL EDPQLHAQAY VRLHMLLQTA VPARREEACY VLSKLEAALG RVLNTSSLES ATDEAGSPLA AAAAAAAAER CSWLVPLVRT LLDRAYEPLG LQWGLPSLPP TNGSPTFFED FQAFCATPEW RHFIDKQVQP TMSQFEMDTY AKSHDLMSGF WNACYDMLMS SGQRRQWERA QSRRAFQELV LEPAQRRARL EGLRYTAVLK QQATQHSMAL LHWGALWRQL ASPCGAWALR DTPIPRWKLS SAETYSRMRL KLVPNHHFDP HLEASALRDN LGEVPLTPTE EASLPLAVTK EAKVSTPPEL LQEDQLGEDE LAELETPMEA AELDEQREKL VLSAECQLVT VVAVVPGLLE VTTQNVYFYD GSTERVETEE GIGYDFRRPL AQLREVHLRR FNLRRSALEL FFIDQANYFL NFPCKVGTTP VSSPSQTPRP QPGPIPPHTQ VRNQVYSWLL RLRPPSQGYL SSRSPQEMLR ASGLTQKWVQ REISNFEYLM QLNTIAGRTY NDLSQYPVFP WVLQDYVSPT LDLSNPAVFR DLSKPIGVVN PKHAQLVREK YESFEDPAGT IDKFHYGTHY SNAAGVMHYL IRVEPFTSLH VQLQSGRFDC SDRQFHSVAA AWQARLESPA DVKELIPEFF YFPDFLENQN GFDLGCLQLT NEKVGDVVLP PWASSPEDFI QQHRQALESE YVSAHLHEWI DLIFGYKQRG PAAEEALNVF YYCTYEGAVD LDHVTDERER KALEGIISNF GQTPCQLLKE PHPTRLSAEE AAHRLARLDT NSPSIFQHLD ELKAFFAEVV SDGVPLVLAL VPHRQPHSFI TQGSPDLLVT VSASGLLGTH SWLPYDRNIS NYFSFSKDPT MGSHKTQRLL SGPWVPGSGV SGQALAVAPD GKLLFSGGHW DGSLRVTALP RGKLLSQLSC HLDVVTCLAL DTCGIYLISG SRDTTCMVWR LLHQGGLSVG LAPKPVQVLY GHGAAVSCVA ISTELDMAVS GSEDGTVIIH TVRRGQFVAA LRPLGATFPG PIFHLALGSE GQIVVQSSAW ERPGAQVTYS LHLYSVNGKL RASLPLAEQP TALTVTEDFV LLGTAQCALH ILQLNTLLPA APPLPMKVAI RSVAVTKERS HVLVGLEDGK LIVVVAGQPS EVRSSQFARK LWRSSRRISQ VSSGETEYNP TEAR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.