Details for: FBXO28
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: neuron (CL0000540)
Fold Change: 1.71
Marker Score: 6,951 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.68
Marker Score: 103,203 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.61
Marker Score: 15,334 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.55
Marker Score: 14,602 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.55
Marker Score: 13,318 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.51
Marker Score: 15,553 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.48
Marker Score: 54,639 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167,990 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.46
Marker Score: 5,631 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.46
Marker Score: 21,763 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.45
Marker Score: 55,104 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.45
Marker Score: 28,849 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.4
Marker Score: 2,160 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.39
Marker Score: 10,654 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.27
Marker Score: 5,283 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.12
Marker Score: 23,913 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.11
Marker Score: 1,282 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.09
Marker Score: 318 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.08
Marker Score: 1,359 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.08
Marker Score: 5,010 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.02
Marker Score: 4,418 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.01
Marker Score: 1,949 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.01
Marker Score: 1,262 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,703 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,928 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,394 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.98
Marker Score: 1,055 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.96
Marker Score: 1,085 - Cell Name: fat cell (CL0000136)
Fold Change: 0.96
Marker Score: 535 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.95
Marker Score: 6,132 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,398 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 481 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 437 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.92
Marker Score: 3,831 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.91
Marker Score: 1,989 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.9
Marker Score: 998 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,706 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.9
Marker Score: 1,460 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.9
Marker Score: 4,818 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.89
Marker Score: 793 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.87
Marker Score: 522 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.87
Marker Score: 19,389 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.86
Marker Score: 312 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.86
Marker Score: 418 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 309 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4,860 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.83
Marker Score: 12,924 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.82
Marker Score: 237 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.82
Marker Score: 3,021 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.81
Marker Score: 565 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.81
Marker Score: 404 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.81
Marker Score: 425 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.8
Marker Score: 1,972 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.8
Marker Score: 300 - Cell Name: podocyte (CL0000653)
Fold Change: 0.8
Marker Score: 296 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.8
Marker Score: 689 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.79
Marker Score: 2,823 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.79
Marker Score: 784 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.79
Marker Score: 828 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.79
Marker Score: 315 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 594 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.77
Marker Score: 1,301 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.77
Marker Score: 1,812 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.76
Marker Score: 12,165 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.76
Marker Score: 913 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.75
Marker Score: 1,063 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.74
Marker Score: 272 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.74
Marker Score: 24,895 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.73
Marker Score: 1,487 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.72
Marker Score: 422 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 375 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.72
Marker Score: 3,025 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.72
Marker Score: 660 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.72
Marker Score: 489 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.72
Marker Score: 300 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.71
Marker Score: 356 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.71
Marker Score: 2,945 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.71
Marker Score: 872 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.7
Marker Score: 12,460 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.7
Marker Score: 1,673 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.7
Marker Score: 1,985 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.69
Marker Score: 432 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.69
Marker Score: 596 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.69
Marker Score: 737 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.69
Marker Score: 654 - Cell Name: contractile cell (CL0000183)
Fold Change: 0.68
Marker Score: 370 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.68
Marker Score: 462 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.67
Marker Score: 1,196 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.67
Marker Score: 712 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 612 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.67
Marker Score: 182 - Cell Name: basal cell (CL0000646)
Fold Change: 0.66
Marker Score: 851 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.66
Marker Score: 969 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.66
Marker Score: 287 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.66
Marker Score: 538 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.65
Marker Score: 934 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.65
Marker Score: 165 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.65
Marker Score: 413
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 54284367
Symbol: FBX28_HUMAN
Name: F-box only protein 28
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9455484
Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.
PubMed ID: 9455484
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20813266
Title: The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics.
PubMed ID: 20813266
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 21248752
Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.
PubMed ID: 21248752
DOI: 10.1038/nature09639
PubMed ID: 33280099
Title: FBXO28 causes developmental and epileptic encephalopathy with profound intellectual disability.
PubMed ID: 33280099
DOI: 10.1111/epi.16784
Sequence Information:
- Length: 368
- Mass: 41149
- Checksum: 500A2583AB7315E6
- Sequence:
MAAAAEERMA EEGGGGQGDG GSSLASGSTQ RQPPPPAPQH PQPGSQALPA PALAPDQLPQ NNTLVALPIV AIENILSFMS YDEISQLRLV CKRMDLVCQR MLNQGFLKVE RYHNLCQKQV KAQLPRRESE RRNHSLARHA DILAAVETRL SLLNMTFMKY VDSNLCCFIP GKVIDEIYRV LRYVNSTRAP QRAHEVLQEL RDISSMAMEY FDEKIVPILK RKLPGSDVSG RLMGSPPVPG PSAALTTMQL FSKQNPSRQE VTKLQQQVKT NGAGVTVLRR EISELRTKVQ EQQKQLQDQD QKLLEQTQII GEQNARLAEL ERKLREVMES AVGNSSGSGQ NEESPRKRKK ATEAIDSLRK SKRLRNRK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.