Details for: RRP12

Gene ID: 23223

Symbol: RRP12

Ensembl ID: ENSG00000052749

Description: ribosomal RNA processing 12 homolog

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,342
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.29
    Marker Score: 12,119
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.24
    Marker Score: 69,086
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.23
    Marker Score: 1,486
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.2
    Marker Score: 1,852
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.17
    Marker Score: 11,080
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.15
    Marker Score: 369
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.1
    Marker Score: 2,327
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.09
    Marker Score: 17,129
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.08
    Marker Score: 66,375
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.03
    Marker Score: 2,101
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.03
    Marker Score: 10,621
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.02
    Marker Score: 37,694
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.01
    Marker Score: 8,704
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.01
    Marker Score: 4,169
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1
    Marker Score: 1,952
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1
    Marker Score: 4,183
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,745
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,970
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.99
    Marker Score: 2,342
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,399
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.98
    Marker Score: 999
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.98
    Marker Score: 956
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.95
    Marker Score: 1,195
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,404
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 487
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 443
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.93
    Marker Score: 559
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,718
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.9
    Marker Score: 258
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,293
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.87
    Marker Score: 313
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4,932
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.85
    Marker Score: 266
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.82
    Marker Score: 1,324
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.79
    Marker Score: 332
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 603
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.79
    Marker Score: 869
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.76
    Marker Score: 1,109
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.76
    Marker Score: 304
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.75
    Marker Score: 748
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.75
    Marker Score: 2,570
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.75
    Marker Score: 436
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 381
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.73
    Marker Score: 4,404
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.71
    Marker Score: 2,994
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 0.71
    Marker Score: 3,487
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.7
    Marker Score: 10,526
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.7
    Marker Score: 2,483
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.69
    Marker Score: 836
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.69
    Marker Score: 629
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.68
    Marker Score: 1,678
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.67
    Marker Score: 475
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.67
    Marker Score: 13,359
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.67
    Marker Score: 389
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.65
    Marker Score: 263
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.64
    Marker Score: 435
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.64
    Marker Score: 7,439
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.64
    Marker Score: 855
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.64
    Marker Score: 669
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.63
    Marker Score: 173
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.63
    Marker Score: 557
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.62
    Marker Score: 896
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.61
    Marker Score: 811
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.61
    Marker Score: 1,155
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.6
    Marker Score: 642
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6
    Marker Score: 882
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.6
    Marker Score: 645
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.6
    Marker Score: 5,179
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.58
    Marker Score: 2,372
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.58
    Marker Score: 503
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.58
    Marker Score: 383
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.57
    Marker Score: 274
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.57
    Marker Score: 12,771
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 0.57
    Marker Score: 1,377
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.57
    Marker Score: 1,413
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 0.56
    Marker Score: 3,427
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.56
    Marker Score: 12,008
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.56
    Marker Score: 21,342
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.55
    Marker Score: 1,376
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.55
    Marker Score: 592
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 435
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.54
    Marker Score: 394
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.54
    Marker Score: 494
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 0.53
    Marker Score: 127
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.53
    Marker Score: 340
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.53
    Marker Score: 1,164
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.53
    Marker Score: 137
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.53
    Marker Score: 2,034
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.52
    Marker Score: 878
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.52
    Marker Score: 672
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.52
    Marker Score: 2,008
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.51
    Marker Score: 179
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.51
    Marker Score: 1,247
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.51
    Marker Score: 256
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.5
    Marker Score: 364
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.5
    Marker Score: 244
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.5
    Marker Score: 175
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.49
    Marker Score: 935

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RRP12 is a homolog of the ribosomal RNA processing protein, RRP12, which plays a crucial role in the processing and maturation of ribosomal RNA (rRNA). The RRP12 gene is primarily expressed in cells involved in immune responses, such as mural cells, monocytes, and macrophages. Its expression is also observed in neurons, including those involved in glutamatergic transmission, which suggests a potential role in synaptic plasticity and neuronal function. **Pathways and Functions:** The RRP12 gene is involved in various cellular processes, including: 1. **RNA processing**: RRP12 is a key player in the processing and maturation of rRNA, which is essential for protein synthesis and cellular function. 2. **Immune response**: RRP12 is expressed in cells involved in the immune response, such as monocytes and macrophages, suggesting a potential role in the regulation of immune cell function and the response to pathogens. 3. **Neuronal function**: The expression of RRP12 in neurons suggests a potential role in synaptic plasticity and neuronal function, particularly in glutamatergic transmission. 4. **Cellular stress response**: RRP12 has been implicated in the regulation of cellular stress response, including the response to DNA damage and oxidative stress. **Clinical Significance:** The dysregulation of RRP12 has been implicated in various immunological disorders, including: 1. **Autoimmune diseases**: RRP12 has been linked to the development of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, where the immune response is dysregulated. 2. **Inflammatory disorders**: The expression of RRP12 in monocytes and macrophages suggests a potential role in the regulation of inflammatory responses, which is implicated in conditions such as atherosclerosis and chronic inflammatory diseases. 3. **Cancer**: RRP12 has been implicated in the regulation of cellular stress response and the development of cancer, where the dysregulation of immune responses can contribute to tumor progression. In conclusion, the RRP12 gene plays a complex and multifaceted role in cellular processes, including RNA processing, immune response, neuronal function, and cellular stress response. Its dysregulation has been implicated in various immunological disorders, highlighting the need for further research into the mechanisms underlying its function and the potential therapeutic applications of RRP12 in the treatment of these diseases. **Proteins:** The RRP12 gene encodes for two protein isoforms, RRP12_HUMAN and B3KMR5_HUMAN, which share similar structural and functional characteristics. The RRP12_HUMAN isoform is the primary protein product of the gene and is involved in the processing and maturation of rRNA, while the B3KMR5_HUMAN isoform is a splice variant that is expressed in specific cell types. **Significantly expressed cells:** The RRP12 gene is expressed in a wide range of cell types, including: 1. Mural cells 2. Near-projecting glutamatergic cortical neurons 3. CD14-positive, CD16-negative classical monocytes 4. Mesangial cells 5. L5 extratelencephalic projecting glutamatergic cortical neurons 6. Corticothalamic-projecting glutamatergic cortical neurons 7. Mononuclear cells 8. Pancreatic acinar cells 9. Cardiac muscle myoblasts 10. L2/3-6 intratelencephalic projecting glutamatergic neurons

Genular Protein ID: 4143879713

Symbol: RRP12_HUMAN

Name: RRP12-like protein

UniProtKB Accession Codes:

Q5JTH9 B4DK00 E9PCK7 Q5JTH8 Q69YK4 Q96E87 Q9BUH3 Q9Y4C7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 CarbonylDB 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EMDB 8 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 8 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 3 SAM 1 SMR 1 STRING 1 SUPFAM 1 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

Sequence Information:

  • Length: 1297
  • Mass: 143702
  • Checksum: 23A203CBFB7C46D3
  • Sequence:
    • MGRSGKLPSG VSAKLKRWKK GHSSDSNPAI CRHRQAARSR FFSRPSGRSD LTVDAVKLHN 
ELQSGSLRLG KSEAPETPME EEAELVLTEK SSGTFLSGLS DCTNVTFSKV QRFWESNSAA 
HKEICAVLAA VTEVIRSQGG KETETEYFAA LMTTMEAVES PESLAAVAYL LNLVLKRVPS 
PVLIKKFSDT SKAFMDIMSA QASSGSTSVL RWVLSCLATL LRKQDLEAWG YPVTLQVYHG 
LLSFTVHPKP KIRKAAQHGV CSVLKGSEFM FEKAPAHHPA AISTAKFCIQ EIEKSGGSKE 
ATTTLHMLTL LKDLLPCFPE GLVKSCSETL LRVMTLSHVL VTACAMQAFH SLFHARPGLS 
TLSAELNAQI ITALYDYVPS ENDLQPLLAW LKVMEKAHIN LVRLQWDLGL GHLPRFFGTA 
VTCLLSPHSQ VLTAATQSLK EILKECVAPH MADIGSVTSS ASGPAQSVAK MFRAVEEGLT 
YKFHAAWSSV LQLLCVFFEA CGRQAHPVMR KCLQSLCDLR LSPHFPHTAA LDQAVGAAVT 
SMGPEVVLQA VPLEIDGSEE TLDFPRSWLL PVIRDHVQET RLGFFTTYFL PLANTLKSKA 
MDLAQAGSTV ESKIYDTLQW QMWTLLPGFC TRPTDVAISF KGLARTLGMA ISERPDLRVT 
VCQALRTLIT KGCQAEADRA EVSRFAKNFL PILFNLYGQP VAAGDTPAPR RAVLETIRTY 
LTITDTQLVN SLLEKASEKV LDPASSDFTR LSVLDLVVAL APCADEAAIS KLYSTIRPYL 
ESKAHGVQKK AYRVLEEVCA SPQGPGALFV QSHLEDLKKT LLDSLRSTSS PAKRPRLKCL 
LHIVRKLSAE HKEFITALIP EVILCTKEVS VGARKNAFAL LVEMGHAFLR FGSNQEEALQ 
CYLVLIYPGL VGAVTMVSCS ILALTHLLFE FKGLMGTSTV EQLLENVCLL LASRTRDVVK 
SALGFIKVAV TVMDVAHLAK HVQLVMEAIG KLSDDMRRHF RMKLRNLFTK FIRKFGFELV 
KRLLPEEYHR VLVNIRKAEA RAKRHRALSQ AAVEEEEEEE EEEEPAQGKG DSIEEILADS 
EDEEDNEEEE RSRGKEQRKL ARQRSRAWLK EGGGDEPLNF LDPKVAQRVL ATQPGPGRGR 
KKDHGFKVSA DGRLIIREEA DGNKMEEEEG AKGEDEEMAD PMEDVIIRNK KHQKLKHQKE 
AEEEELEIPP QYQAGGSGIH RPVAKKAMPG AEYKAKKAKG DVKKKGRPDP YAYIPLNRSK 
LNRRKKMKLQ GQFKGLVKAA RRGSQVGHKN RRKDRRP

Genular Protein ID: 615237356

Symbol: B3KMR5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KMR5

Database IDs:

ARBA 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 3 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 1297
  • Mass: 143672
  • Checksum: 8CDD575006CF495E
  • Sequence:
    • MGRSGKLPSG VSAKLKRWKK GHSSDSNPAI CRHRQAARSR FFSRPSGRSD LTVDAVKLHN 
ELQSGSLRLG KSEAPETPME EEAELVLTEK SSGTFLSGLS DCTNVTFSKV QRFWESNSAA 
HKEICAVLAA VTEVIRSQGG KETETEYFAA LMTTMEAVES PESLAAVAYL LNLVLKRVPS 
PVLIKKFSDA SKAFMDIMSA QASSGSTSVL RWVLSCLATL LRKQDLEAWG YPVTLQVYHG 
LLSFTVHPKP KIRKAAQHGV CSVLKGSEFM FEKAPAHHPA AISTAKFCIQ EIEKSGGSKE 
ATTTLHMLTL LKDLLPCFPE GLVKSCSETL LRVMTLSHVL VTACAMQAFH SLFHARPGLS 
TLSAELNAQI ITALYDYVPS ENDLQPLLAW LKVMEKAHIN LVRLQWDLGL GHLPRFFGTA 
VTCLLSPHSQ VLTAATQSLK EILKECVAPH MADIGSVTSS ASGPAQSVAK MFRAVEEGLT 
YKFHAAWSSV LQLLCVFFEA CGRQAHPVMR KCLQSLCDLR LSPHFPHTAA LDQAVGAAVT 
SMGPEVVLRA VPLEIDGSEE TLDFPRSWLL PVIRDHVQET RLGFFTTYFL PLANTLKSKA 
MDLAQAGSTV ESKIYDTLQW QMWTLLPGFC TRPTDVAISF KGLARTLGMA ISERPDLRVT 
VCQALRTLIT KGCQAEADRA EVSRFAKNFL PILFNLYGQP VAAGDTPAPR RAVLETIRTY 
LTITDTQLVN SLLEKASEKV LDPASSDFTR LSVLDLVVAL APCADEAAIS KLYSTIRPYL 
ESKAHGVQKK AYRVLEEVCA SPQGPGALFV QSHLEDLKKT LLDSLRSTSS PAKRPRLKCL 
LHIVRKLSAE HKEFITALIP EVILCTKEVS VGARKNAFAL LVEMGHAFLR FGSNQEEALQ 
CYLVLIYPGL VGAVTMVSCS ILALTHLLFE FKGLMGTSTV EQLLENVCLL LASRTRDVVK 
SALGFIKVAV TVMDVAHLAK HVQLVMEAIG KLSDDMRRHF RMKLRNLFTK FIRKFGFELV 
KRLLPEEYHR VLVNIRKAEA RAKRHRALSQ AAVEEEEEEE EEEEPAQGKG DSIEEILADS 
EDEEDNEEEE RSRGKEQRKL ARQRSRAWLK EGGGDEPLNF LDPKVAQRVL ATQPGPGRGR 
KKDHGFKVSA DGRLIIREEA DGNKMEEEEG AKGEDEEMAD PMEDVIIRNK KHQKLKHQKE 
AEEEELEIPP QYQAGGSGIH RPVAKKAMPG AEYKAKKAKG DVKKKGRPDP YAYIPLNRSK 
LNRRKKMKLQ GQFKGLVKAA QRGSQVGHKN RRKDRRP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.