Details for: EXOC6B
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 5.58
Marker Score: 4,580 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 5.43
Marker Score: 183,308 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 4.93
Marker Score: 110,108 - Cell Name: stellate neuron (CL0000122)
Fold Change: 4.49
Marker Score: 24,105 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 4.48
Marker Score: 15,017 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 4.29
Marker Score: 22,498 - Cell Name: granule cell (CL0000120)
Fold Change: 4.17
Marker Score: 31,426 - Cell Name: macroglial cell (CL0000126)
Fold Change: 4.02
Marker Score: 9,229 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 3.86
Marker Score: 9,240 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.71
Marker Score: 8,136 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 3.58
Marker Score: 4,056 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 3.57
Marker Score: 4,799 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.44
Marker Score: 4,158 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 3.41
Marker Score: 12,126 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 3.38
Marker Score: 14,158 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 3.37
Marker Score: 15,601 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 3.36
Marker Score: 14,005 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 3.34
Marker Score: 1,858 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 3.28
Marker Score: 2,833 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 3.26
Marker Score: 2,894 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 3.23
Marker Score: 1,875 - Cell Name: renal principal cell (CL0005009)
Fold Change: 3.19
Marker Score: 2,460 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 3.05
Marker Score: 5,877 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.97
Marker Score: 3,701 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 2.96
Marker Score: 2,231 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.9
Marker Score: 61,855 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.88
Marker Score: 1,722 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.88
Marker Score: 3,313 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.83
Marker Score: 828 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 2.8
Marker Score: 1,344 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.77
Marker Score: 55,191 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.72
Marker Score: 48,317 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 2.72
Marker Score: 1,431 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.69
Marker Score: 20,641 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.69
Marker Score: 40,251 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 2.64
Marker Score: 1,154 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.64
Marker Score: 4,439 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.62
Marker Score: 99,519 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.57
Marker Score: 7,329 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.56
Marker Score: 10,603 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.55
Marker Score: 1,773 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.55
Marker Score: 810 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.54
Marker Score: 1,479 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 2.52
Marker Score: 725 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.51
Marker Score: 1,409 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.46
Marker Score: 777 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.43
Marker Score: 1,419 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 2.42
Marker Score: 885 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.41
Marker Score: 1,011 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.41
Marker Score: 6,036 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.4
Marker Score: 88,606 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.38
Marker Score: 1,292 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.35
Marker Score: 3,305 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.32
Marker Score: 892 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.3
Marker Score: 8,888 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2.29
Marker Score: 1,509 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.28
Marker Score: 2,519 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.17
Marker Score: 20,459 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.17
Marker Score: 1,071 - Cell Name: fat cell (CL0000136)
Fold Change: 2.12
Marker Score: 1,187 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.11
Marker Score: 2,012 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.06
Marker Score: 126,739 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 2.02
Marker Score: 2,519 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2
Marker Score: 20,669 - Cell Name: neuron (CL0000540)
Fold Change: 2
Marker Score: 8,144 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.99
Marker Score: 517 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.95
Marker Score: 709 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.92
Marker Score: 18,233 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.92
Marker Score: 953 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.87
Marker Score: 2,314 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.86
Marker Score: 16,012 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.82
Marker Score: 6,455 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.81
Marker Score: 494 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.78
Marker Score: 1,923 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.78
Marker Score: 28,535 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.71
Marker Score: 519 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.68
Marker Score: 1,453 - Cell Name: podocyte (CL0000653)
Fold Change: 1.66
Marker Score: 615 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.63
Marker Score: 2,365 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.62
Marker Score: 2,503 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.62
Marker Score: 512 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.6
Marker Score: 1,715 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.59
Marker Score: 573 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.58
Marker Score: 596 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.58
Marker Score: 401 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.57
Marker Score: 5,144 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 1.56
Marker Score: 515 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.55
Marker Score: 1,017 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.51
Marker Score: 474 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.41
Marker Score: 284 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.38
Marker Score: 712 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.36
Marker Score: 1,929 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 1.36
Marker Score: 357 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.34
Marker Score: 21,035 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.33
Marker Score: 1,602 - Cell Name: trophoblast giant cell (CL0002488)
Fold Change: 1.31
Marker Score: 425 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.3
Marker Score: 442 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.3
Marker Score: 8,352 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.24
Marker Score: 465 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 1.22
Marker Score: 390
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2312276850
Symbol: EXC6B_HUMAN
Name: Exocyst complex component 6B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11406615
Title: The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene.
PubMed ID: 11406615
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 26669664
Title: A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene.
PubMed ID: 26669664
PubMed ID: 30284759
Title: Confirmation of spondylo-epi-metaphyseal dysplasia with joint laxity, EXOC6B type.
PubMed ID: 30284759
DOI: 10.1002/ajmg.a.40631
Sequence Information:
- Length: 811
- Mass: 94201
- Checksum: A666EC6A0B82D9A2
- Sequence:
MERGKMAEAE SLETAAEHER ILREIESTDT ACIGPTLRSV YDGEEHGRFM EKLETRIRNH DREIEKMCNF HYQGFVDSIT ELLKVRGEAQ KLKNQVTDTN RKLQHEGKEL VIAMEELKQC RLQQRNISAT VDKLMLCLPV LEMYSKLRDQ MKTKRHYPAL KTLEHLEHTY LPQVSHYRFC KVMVDNIPKL REEIKDVSMS DLKDFLESIR KHSDKIGETA MKQAQQQRNL DNIVLQQPRI GSKRKSKKDA YIIFDTEIES TSPKSEQDSG ILDVEDEEDD EEVPGAQDLV DFSPVYRCLH IYSVLGARET FENYYRKQRR KQARLVLQPP SNMHETLDGY RKYFNQIVGF FVVEDHILHT TQGLVNRAYI DELWEMALSK TIAALRTHSS YCSDPNLVLD LKNLIVLFAD TLQVYGFPVN QLFDMLLEIR DQYSETLLKK WAGIFRNILD SDNYSPIPVT SEEMYKKVVG QFPFQDIELE KQPFPKKFPF SEFVPKVYNQ IKEFIYACLK FSEDLHLSST EVDDMIRKST NLLLTRTLSN SLQNVIKRKN IGLTELVQII INTTHLEKSC KYLEEFITNI TNVLPETVHT TKLYGTTTFK DARHAAEEEI YTNLNQKIDQ FLQLADYDWM TGDLGNKASD YLVDLIAFLR STFAVFTHLP GKVAQTACMS ACKHLATSLM QLLLEAEVRQ LTLGALQQFN LDVRECEQFA RSGPVPGFQE DTLQLAFIDL RQLLDLFIQW DWSTYLADYG QPNCKYLRVN PVTALTLLEK MKDTSRKNNM FAQFRKNERD KQKLIDTVAK QLRGLISSHH S
Genular Protein ID: 2310440468
Symbol: A0A0U1RRB6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 815
- Mass: 94686
- Checksum: C672B5D74D071BD7
- Sequence:
MERGKMAEAE SLETAAEHER ILREIESTDT ACIGPTLRSV YDGEEHGRFM EKLETRIRNH DREIEKMCNF HYQGFVDSIT ELLKVRGEAQ KLKNQVTDTN RKLQHEGKEL VIAMEELKQC RLQQRNISAT VDKLMLCLPV LEMYSKLRDQ MKTKRHYPAL KTLEHLEHTY LPQVSHYRFC KVMVDNIPKL REEIKDVSMS DLKDFLESIR KHSDKIGETA MKQAQQQRNL DNIVLQQPRI GSKRKSKKDA YIIFDTEIES TSPKSEQDSG ILDVEDEEDD EEVPGAQDLV DFSPVYRCLH IYSVLGARET FENYYRKQRR KQARLVLQPP SNMHETLDGY RKYFNQIVGF FVVEDHILHT TQGLVNRAYI DELWEMALSK TIAALRTHSS YCSDPNLVLD LKNLIVLFAD TLQVYGFPVN QLFDMLLEIR DQYSETLLKK WAGIFRNILD SDNYSPIPVT SEEMYKKVVG QFPFQDIELE KQPFPKKFPF SEFVPKVYNQ IKEFIYACLK FSEDLHLSST EVDDMIRKST NLLLTRTLSN SLQNVIKRKN IGLTELVQII INTTHLEKSC KYLEEFITNI TNVLPETVHT TKLYGTTTFK DARHAAEEEI YTNLNQKIDQ FLQLADYDWM TGDLGNKASD YLVDLIAFLR STFAVFTHLP GKVAQTACMS ACKHLATSLM QLLLEAEVRQ LTLGALQQFN LDVRECEQFA RSGPVPGFQE DTLQLAFIDL RQLLDLFIQW DWSTYLADYG QPNCKYLRVN PVTALTLLEK ISREMKDTSR KNNMFAQFRK NERDKQKLID TVAKQLRGLI SSHHS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.