Details for: PACS2

Gene ID: 23241

Symbol: PACS2

Ensembl ID: ENSG00000179364

Description: phosphofurin acidic cluster sorting protein 2

Associated with

Other Information

Genular Protein ID: 342003861

Symbol: PACS2_HUMAN

Name: PACS1-like protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15692567

Title: PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis.

PubMed ID: 15692567

DOI: 10.1038/sj.emboj.7600559

PubMed ID: 9628581

Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9628581

DOI: 10.1093/dnares/5.1.31

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15692563

Title: Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

PubMed ID: 15692563

DOI: 10.1038/sj.emboj.7600566

PubMed ID: 18296443

Title: HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.

PubMed ID: 18296443

DOI: 10.1074/jbc.m707572200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29656858

Title: A recurrent de novo PACS2 heterozygous missense variant causes neonatal-onset developmental epileptic encephalopathy, facial dysmorphism, and cerebellar dysgenesis.

PubMed ID: 29656858

DOI: 10.1016/j.ajhg.2018.03.005

PubMed ID: 34642815

Title: WDR37 syndrome: identification of a distinct new cluster of disease-associated variants and functional analyses of mutant proteins.

PubMed ID: 34642815

DOI: 10.1007/s00439-021-02384-y

Sequence Information:

  • Length: 889
  • Mass: 97702
  • Checksum: 0AAFC1515B13A58D
  • Sequence:
  • MAERGRLGLP GAPGALNTPV PMNLFATWEV DGSSPSCVPR LCSLTLKKLV VFKELEKELI 
    SVVIAVKMQG SKRILRSHEI VLPPSGQVET DLALTFSLQY PHFLKREGNK LQIMLQRRKR 
    YKNRTILGYK TLAAGSISMA EVMQHPSEGG QVLSLCSSIK EAPVKAAEIW IASLSSQPID 
    HEDSTMQAGP KAKSTDNYSE EEYESFSSEQ EASDDAVQGQ DLDEDDFDVG KPKKQRRSIV 
    RTTSMTRQQN FKQKVVALLR RFKVSDEVLD SEQDPAEHIP EAEEDLDLLY DTLDMEHPSD 
    SGPDMEDDDS VLSTPKPKLR PYFEGLSHSS SQTEIGSIHS ARSHKEPPSP ADVPEKTRSL 
    GGRQPSDSVS DTVALGVPGP REHPGQPEDS PEAEASTLDV FTERLPPSGR ITKTESLVIP 
    STRSEGKQAG RRGRSTSLKE RQAARPQNER ANSLDNERCP DARSQLQIPR KTVYDQLNHI 
    LISDDQLPEN IILVNTSDWQ GQFLSDVLQR HTLPVVCTCS PADVQAAFST IVSRIQRYCN 
    CNSQPPTPVK IAVAGAQHYL SAILRLFVEQ LSHKTPDWLG YMRFLVIPLG SHPVARYLGS 
    VDYRYNNFFQ DLAWRDLFNK LEAQSAVQDT PDIVSRITQY IAGANCAHQL PIAEAMLTYK 
    QKSPDEESSQ KFIPFVGVVK VGIVEPSSAT SGDSDDAAPS GSGTLSSTPP SASPAAKEAS 
    PTPPSSPSVS GGLSSPSQGV GAELMGLQVD YWTAAQPADR KRDAEKKDLP VTKNTLKCTF 
    RSLQVSRLPS SGEAAATPTM SMTVVTKEKN KKVMFLPKKA KDKDVESKSQ CIEGISRLIC 
    TARQQQNMLR VLIDGVECSD VKFFQLAAQW SSHVKHFPIC IFGHSKATF

Genular Protein ID: 1653884789

Symbol: Q8N7J0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 229
  • Mass: 24797
  • Checksum: 70CBA0CB4AE3A708
  • Sequence:
  • MKIPAGWPDQ RGRHFGAVGA ARYPVQGLGG SPGHSPQSVL GPMLCVGSMP STQQERASLT 
    TPAPSVLLLP SKPALWGLHR RSWGSWGPPR GPDRPWGLLA WFRKMEHCKR PCSESKRRAG 
    WASSRGWRGL HPCWPERWPT FLTCDRPALP GRPPQVAEQG DFVVVRGQDV AWCAASAPWV 
    QASEVACVQE AEPQPLPARA PPHQGLLLHL GPGAWGTPQG GGEGRKVSH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.