OTUD3 | ENSG00000169914 | NCBI 23252

Details for: OTUD3

Gene ID: 23252

Symbol: OTUD3

Ensembl ID: ENSG00000169914

Description: OTU deubiquitinase 3

Associated with

Deubiquitination
(R-HSA-5688426)
Intracellular signaling by second messengers
(R-HSA-9006925)
Metabolism of proteins
(R-HSA-392499)
Ovarian tumor domain proteases
(R-HSA-5689896)
Pip3 activates akt signaling
(R-HSA-1257604)
Post-translational protein modification
(R-HSA-597592)
Pten regulation
(R-HSA-6807070)
Regulation of pten stability and activity
(R-HSA-8948751)
Signal transduction
(R-HSA-162582)
Cellular response to nutrient levels
(GO:0031669)
Cysteine-type deubiquitinase activity
(GO:0004843)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein k6-linked deubiquitination
(GO:0044313)
Protein k11-linked deubiquitination
(GO:0035871)
Protein k27-linked deubiquitination
(GO:1990167)
Protein k48-linked deubiquitination
(GO:0071108)
Protein stabilization
(GO:0050821)
Proteolysis
(GO:0006508)

Other Information

Proteins

OTUD3_HUMAN

Genular Protein ID: 2621653256

Symbol: OTUD3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5T2D3 O75047

Database IDs:

Citations:

PubMed ID: 9455484

Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PubMed ID: 9455484

DOI: 10.1093/dnares/4.5.345

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 32011234

Title: Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized.

PubMed ID: 32011234

DOI: 10.7554/elife.54023

PubMed ID: 23827681

Title: OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

PubMed ID: 23827681

DOI: 10.1016/j.cell.2013.05.046

PubMed ID: 35675826

Title: Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses.

PubMed ID: 35675826

DOI: 10.1016/j.cmet.2022.05.005

Sequence Information:

Length: 398
Mass: 45124
Checksum: 9C16E610CF1E3C5A
Sequence:

MSRKQAAKSR PGSGSRKAEA ERKRDERAAR RALAKERRNR PESGGGGGCE EEFVSFANQL 
QALGLKLREV PGDGNCLFRA LGDQLEGHSR NHLKHRQETV DYMIKQREDF EPFVEDDIPF 
EKHVASLAKP GTFAGNDAIV AFARNHQLNV VIHQLNAPLW QIRGTEKSSV RELHIAYRYG 
EHYDSVRRIN DNSEAPAHLQ TDFQMLHQDE SNKREKIKTK GMDSEDDLRD EVEDAVQKVC 
NATGCSDFNL IVQNLEAENY NIESAIIAVL RMNQGKRNNA EENLEPSGRV LKQCGPLWEE 
GGSGARIFGN QGLNEGRTEN NKAQASPSEE NKANKNQLAK VTNKQRREQQ WMEKKKRQEE 
RHRHKALESR GSHRDNNRSE AEANTQVTLV KTFAALNI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: OTUD3

Associated with

Other Information

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. PubMed ID: 9455484

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized. PubMed ID: 32011234

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. PubMed ID: 23827681

Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses. PubMed ID: 35675826