Details for: PPIP5K2

Gene ID: 23262

Symbol: PPIP5K2

Ensembl ID: ENSG00000145725

Description: diphosphoinositol pentakisphosphate kinase 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 4.88
    Marker Score: 64,891
  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.42
    Marker Score: 4,229
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.17
    Marker Score: 82,511
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.17
    Marker Score: 80,130
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.08
    Marker Score: 41,457
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.95
    Marker Score: 14,921
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.9
    Marker Score: 7,884
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.85
    Marker Score: 17,443
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.82
    Marker Score: 27,217
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.82
    Marker Score: 111,679
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.81
    Marker Score: 880
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.81
    Marker Score: 7,572
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.8
    Marker Score: 6,947
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.79
    Marker Score: 8,294
  • Cell Name: interneuron (CL0000099)
    Fold Change: 1.73
    Marker Score: 791
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.73
    Marker Score: 16,390
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.7
    Marker Score: 1,874
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.7
    Marker Score: 985
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.67
    Marker Score: 974
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.63
    Marker Score: 14,015
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.59
    Marker Score: 33,987
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.57
    Marker Score: 34,994
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.55
    Marker Score: 3,401
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 1.52
    Marker Score: 923
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.51
    Marker Score: 2,333
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.49
    Marker Score: 472
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.48
    Marker Score: 1,699
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.47
    Marker Score: 5,212
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.46
    Marker Score: 1,963
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.42
    Marker Score: 1,717
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 1.4
    Marker Score: 5,824
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.39
    Marker Score: 405
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.34
    Marker Score: 1,199
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.31
    Marker Score: 504
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.31
    Marker Score: 888
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.26
    Marker Score: 2,424
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.24
    Marker Score: 725
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.23
    Marker Score: 1,328
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.23
    Marker Score: 514
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.2
    Marker Score: 816
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.19
    Marker Score: 376
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.17
    Marker Score: 1,119
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.17
    Marker Score: 1,679
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.17
    Marker Score: 3,130
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.16
    Marker Score: 1,173
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.16
    Marker Score: 892
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.16
    Marker Score: 690
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.15
    Marker Score: 1,112
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.09
    Marker Score: 545
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.09
    Marker Score: 1,175
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.07
    Marker Score: 532
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.07
    Marker Score: 559
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.07
    Marker Score: 599
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.06
    Marker Score: 745
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.05
    Marker Score: 396
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 1.05
    Marker Score: 518
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.04
    Marker Score: 363
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.04
    Marker Score: 657
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.03
    Marker Score: 385
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.02
    Marker Score: 442
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.02
    Marker Score: 685
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.01
    Marker Score: 15,864
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.01
    Marker Score: 277
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.01
    Marker Score: 321
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.01
    Marker Score: 344
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.01
    Marker Score: 367
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.01
    Marker Score: 1,024
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.01
    Marker Score: 531
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1
    Marker Score: 995
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.99
    Marker Score: 1,238
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.99
    Marker Score: 662
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 0.99
    Marker Score: 317
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.99
    Marker Score: 715
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.99
    Marker Score: 400
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.99
    Marker Score: 655
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.98
    Marker Score: 481
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,378
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.98
    Marker Score: 515
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.98
    Marker Score: 2,782
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.97
    Marker Score: 730
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.97
    Marker Score: 279
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.97
    Marker Score: 2,406
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.97
    Marker Score: 3,427
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.96
    Marker Score: 354
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.95
    Marker Score: 1,003
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.95
    Marker Score: 9,632
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.95
    Marker Score: 3,512
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.95
    Marker Score: 1,590
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,381
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.94
    Marker Score: 1,325
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.93
    Marker Score: 521
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.93
    Marker Score: 2,187
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.93
    Marker Score: 5,960
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 472
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.91
    Marker Score: 10,632
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 0.91
    Marker Score: 1,592
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.91
    Marker Score: 2,236
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 428
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.9
    Marker Score: 957
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.9
    Marker Score: 1,134

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PPIP5K2 is a member of the inositol kinase family, which plays a crucial role in the synthesis and metabolism of inositol phosphates. The gene is specifically expressed in various cell types, including cardiac muscle cells, germ cells, and GABAergic cortical interneurons. Notably, PPIP5K2 is also involved in the synthesis of pyrophosphates in the cytosol, which is a critical process for maintaining cellular homeostasis. **Pathways and Functions:** PPIP5K2 is integral to several signaling pathways, including: 1. **Inositol Metabolic Process:** PPIP5K2 is involved in the synthesis of inositol phosphates, which are essential for various cellular processes, including cell signaling, proliferation, and differentiation. 2. **Phosphorylation:** PPIP5K2 catalyzes the phosphorylation of inositol pentakisphosphate (IP5), generating diphosphoinositol pentakisphosphate (DIP5), a crucial intermediate in the inositol metabolic pathway. 3. **Protein Binding:** PPIP5K2 interacts with various proteins, including VIP2, which is involved in the regulation of neuronal excitability and synaptic transmission. **Clinical Significance:** While PPIP5K2 is not directly associated with any specific human diseases, its dysregulation may contribute to various conditions, including: 1. **Neurological Disorders:** PPIP5K2's involvement in GABAergic cortical interneurons suggests its potential role in neurological disorders, such as epilepsy or schizophrenia. 2. **Cardiovascular Disease:** The expression of PPIP5K2 in cardiac muscle cells implies its possible involvement in cardiovascular disease, particularly in the regulation of cardiac function and metabolism. 3. **Cancer:** PPIP5K2's role in the synthesis of pyrophosphates may contribute to cancer development and progression, particularly in tumors with high energy demands. **Conclusion:** In conclusion, PPIP5K2 is a complex gene that plays a multifaceted role in various cellular processes, including inositol metabolism, phosphorylation, and protein binding. While its clinical significance is still unclear, further research is necessary to elucidate the enigmatic role of PPIP5K2 in human health and disease. As an expert immunologist, I believe that a deeper understanding of PPIP5K2's functions and pathways will provide valuable insights into the development of novel therapeutic strategies for various diseases.

Genular Protein ID: 430927692

Symbol: VIP2_HUMAN

Name: Diphosphoinositol pentakisphosphate kinase 2

UniProtKB Accession Codes:

O43314 A1NI53 A6NGS8 Q8TB50

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 18 ChEMBL 1 ChiTaRS 1 DEPOD 1 DNASU 1 DisGeNET 1 EC 2 EMBL 4 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 32 PDBsum 20 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 4 SABIO-RK 1 SAM 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9455477

Title: Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9455477

DOI: 10.1093/dnares/4.5.307

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17690096

Title: Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

PubMed ID: 17690096

DOI: 10.1074/jbc.m704656200

PubMed ID: 17702752

Title: Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.

PubMed ID: 17702752

DOI: 10.1074/jbc.m704655200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21222653

Title: Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain.

PubMed ID: 21222653

DOI: 10.1042/bj20101437

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29590114

Title: Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse.

PubMed ID: 29590114

DOI: 10.1371/journal.pgen.1007297

PubMed ID: 22119861

Title: Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.

PubMed ID: 22119861

DOI: 10.1038/nchembio.733

Sequence Information:

  • Length: 1243
  • Mass: 140407
  • Checksum: A8831DDDAB9B2E6E
  • Sequence:
    • MSEAPRFFVG PEDTEINPGN YRHFFHHADE DDEEEDDSPP ERQIVVGICS MAKKSKSKPM 
KEILERISLF KYITVVVFEE EVILNEPVEN WPLCDCLISF HSKGFPLDKA VAYAKLRNPF 
VINDLNMQYL IQDRREVYSI LQAEGILLPR YAILNRDPNN PKECNLIEGE DHVEVNGEVF 
QKPFVEKPVS AEDHNVYIYY PTSAGGGSQR LFRKIGSRSS VYSPESNVRK TGSYIYEEFM 
PTDGTDVKVY TVGPDYAHAE ARKSPALDGK VERDSEGKEV RYPVILNARE KLIAWKVCLA 
FKQTVCGFDL LRANGQSYVC DVNGFSFVKN SMKYYDDCAK ILGNIVMREL APQFHIPWSI 
PLEAEDIPIV PTTSGTMMEL RCVIAVIRHG DRTPKQKMKM EVRHQKFFDL FEKCDGYKSG 
KLKLKKPKQL QEVLDIARQL LMELGQNNDS EIEENKPKLE QLKTVLEMYG HFSGINRKVQ 
LTYLPHGCPK TSSEEEDSRR EEPSLLLVLK WGGELTPAGR VQAEELGRAF RCMYPGGQGD 
YAGFPGCGLL RLHSTYRHDL KIYASDEGRV QMTAAAFAKG LLALEGELTP ILVQMVKSAN 
MNGLLDSDSD SLSSCQQRVK ARLHEILQKD RDFTAEDYEK LTPSGSISLI KSMHLIKNPV 
KTCDKVYSLI QSLTSQIRHR MEDPKSSDIQ LYHSETLELM LRRWSKLEKD FKTKNGRYDI 
SKIPDIYDCI KYDVQHNGSL KLENTMELYR LSKALADIVI PQEYGITKAE KLEIAKGYCT 
PLVRKIRSDL QRTQDDDTVN KLHPVYSRGV LSPERHVRTR LYFTSESHVH SLLSILRYGA 
LCNESKDEQW KRAMDYLNVV NELNYMTQIV IMLYEDPNKD LSSEERFHVE LHFSPGAKGC 
EEDKNLPSGY GYRPASRENE GRRPFKIDND DEPHTSKRDE VDRAVILFKP MVSEPIHIHR 
KSPLPRSRKT ATNDEESPLS VSSPEGTGTW LHYTSGVGTG RRRRRSGEQI TSSPVSPKSL 
AFTSSIFGSW QQVVSENANY LRTPRTLVEQ KQNPTVGSHC AGLFSTSVLG GSSSAPNLQD 
YARTHRKKLT SSGCIDDATR GSAVKRFSIS FARHPTNGFE LYSMVPSICP LETLHNALSL 
KQVDEFLASI ASPSSDVPRK TAEISSTALR SSPIMRKKVS LNTYTPAKIL PTPPATLKST 
KASSKPATSG PSSAVVPNTS SRKKNITSKT ETHEHKKNTG KKK

Genular Protein ID: 2401434916

Symbol: A0A8V8TMN4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8V8TMN4

Database IDs:

ARBA 9 CDD 1 CTD 1 ChEBI 9 EC 2 EMBL 2 EPD 1 Ensembl 2 GO 6 Gene3D 3 GeneTree 1 HGNC 1 InterPro 5 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 1 Pfam 3 Proteomes 2 RefSeq 1 Rhea 4 RuleBase 1 SAM 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

Sequence Information:

  • Length: 1185
  • Mass: 134169
  • Checksum: 4DA53A3EF5D9A567
  • Sequence:
    • MSEAPRFFVG PEDTEINPGN YRHFFHHADE DDEEEDDSPP ERQIVVGICS MAKKSKSKPM 
KEILERISLF KYITVVVFEE EVILNEPVEN WPLCDCLISF HSKGFPLDKA VAYAKLRNPF 
VINDLNMQYL IQDRREVYSI LQAEGILLPR YAILNRDPNN PKECNLIEGE DHVEVNGEVF 
QKPFVEKPVS AEDHNVYIYY PTSAGGGSQR LFRKIGSRSS VYSPESNVRK TGSYIYEEFM 
PTDGTDVKVY TVGPDYAHAE ARKSPALDGK VERDSEGKEV RYPVILNARE KLIAWKVCLA 
FKQTVCGFDL LRANGQSYVC DVNGFSFVKN SMKYYDDCAK ILGNIVMREL APQFHIPWSI 
PLEAEDIPIV PTTSGTMMEL RCVIAVIRHG DRTPKQKMKM EVRHQKFFDL FEKCDGYKSG 
KLKLKKPKQL QEVLDIARQL LMELGQNNDS EIEENKPKLE QLKTVLEMYG HFSGINRKVQ 
LTYLPHGCPK TSSEEEDSRR EEPSLLLVLK WGGELTPAGR VQAEELGRAF RCMYPGGQGD 
YAGFPGCGLL RLHSTYRHDL KIYASDEGRV QMTAAAFAKG LLALEGELTP ILVQMVKSAN 
MNGLLDSDSD SLSSCQQRVK ARLHEILQKD RDFTAEDYEK LTPSGSISLI KSMHLIKNPV 
KTCDKVYSLI QSLTSQIRHR MEDPKSSDIQ LYHSETLELM LRRWSKLEKD FKTKNGRYDI 
SKIPDIYDCI KYDVQHNGSL KLENTMELYR LSKALADIVI PQEYGITKAE KLEIAKGYCT 
PLVRKIRSDL QRTQDDDTVN KLHPVYSRGV LSPERHVRTR LYFTSESHVH SLLSILRYGA 
LCNESKDEQW KRAMDYLNVV NELNYMTQIV IMLYEDPNKD LSSEERFHVE LHFSPGAKGC 
EEDKNLPSGY GYRPASRENE GRRPFKIDND DEPHTSKRDE VDRAVILFKP MVSEPIHIHR 
KSPLPRSRKT ATNDVVSENA NYLRTPRTLV EQKQNPTVGS HCAGLFSTSV LGGSSSAPNL 
QDYARTHRKK LTSSGCIDDA TRGSAVKRFS ISFARHPTNG FELYSMVPSI CPLETLHNAL 
SLKQVDEFLA SIASPSSDVP RKTAEISSTA LRSSPIMRKK VSLNTYTPAK ILPTPPATLK 
STKASSKPAT SGPSSAVVPN TSSRKKNITS KTETHEHKKN TGKKK

Genular Protein ID: 2597206503

Symbol: A0A087WZV0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WZV0

Database IDs:

ARBA 9 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 9 ChiTaRS 1 DNASU 1 EC 2 EMBL 2 EPD 1 Ensembl 3 GO 9 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 5 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 3 Proteomes 2 RefSeq 1 Rhea 4 RuleBase 1 SAM 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1278
  • Mass: 144362
  • Checksum: EDD60CC5F3FF6D23
  • Sequence:
    • MSEAPRFFVG PEDTEINPGN YRHFFHHADE DDEEEDDSPP ERQIVVGICS MAKKSKSKPM 
KEILERISLF KYITVVVFEE EVILNEPVEN WPLCDCLISF HSKGFPLDKA VAYAKLRNPF 
VINDLNMQYL IQDRREVYSI LQAEGILLPR YAILNRDPNN PKECNLIEGE DHVEVNGEVF 
QKPFVEKPVS AEDHNVYIYY PTSAGGGSQR LFRKIGSRSS VYSPESNVRK TGSYIYEEFM 
PTDGTDVKVY TVGPDYAHAE ARKSPALDGK VERDSEGKEV RYPVILNARE KLIAWKVCLA 
FKQTVCGFDL LRANGQSYVC DVNGFSFVKN SMKYYDDCAK ILGNIVMREL APQFHIPWSI 
PLEAEDIPIV PTTSGTMMEL RCVIAVIRHG DRTPKQKMKM EVRHQKFFDL FEKCDGYKSG 
KLKLKKPKQL QEVLDIARQL LMELGQNNDS EIEENKPKLE QLKTVLEMYG HFSGINRKVQ 
LTYLPHGCPK TSSEEEDSRR EEPSLLLVLK WGGELTPAGR VQAEELGRAF RCMYPGGQGD 
YAGFPGCGLL RLHSTYRHDL KIYASDEGRV QMTAAAFAKG LLALEGELTP ILVQMVKSAN 
MNGLLDSDSD SLSSCQQRVK ARLHEILQKD RDFTAEDYEK LTPSGSISLI KSMHLIKNPV 
KTCDKVYSLI QSLTSQIRHR MEDPKSSDIQ LYHSETLELM LRRWSKLEKD FKTKNGRYDI 
SKIPDIYDCI KYDVQHNGSL KLENTMELYR LSKALADIVI PQEYGITKAE KLEIAKGYCT 
PLVRKIRSDL QRTQDDDTVN KLHPVYSRGV LSPERHVRTR LYFTSESHVH SLLSILRYGA 
LCNTNDSQNE DGGMVKEMES KDEQWKRAMD YLNVVNELNY MTQIVIMLYE DPNKDLSSEE 
RFHVELHFSP GAKGCEEDKN LPSGYGYRPA SRENEGRRPF KIDNDDEPHT SKRDEVDRAV 
ILFKPMVSEP IHIHRKSPLP RSRKTATNDE ESPLSVSSPE GTGTWLHYTS GVGTGRRRRR 
SGEQITSSPV SPKSLAFTSS IFGSWQQVVS ENANYLRTPR TLVEQKQNPT VGSHCAGLFS 
TSVLGGSSSA PNLQDYARTH RKKLTSSGCI DDATRGSAVK RFSISFARHP TNEHLHLYRC 
WSVSSVEFLG SSGFELYSMV PSICPLETLH NALSLKQVDE FLASIASPSS DVPRKTAEIS 
STALRSSPIM RKKVSLNTYT PAKILPTPPA TLKSTKASSK PATSGPSSAV VPNTSSRKKN 
ITSKTETHEH KKNTGKKK

Genular Protein ID: 2511273838

Symbol: B4DGV1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DGV1

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 9 DNASU 1 EC 2 EMBL 2 GO 9 Gene3D 3 GenomeRNAi 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 3 RefSeq 1 Rhea 4 RuleBase 1 SAM 1 SUPFAM 2

Sequence Information:

  • Length: 1270
  • Mass: 143478
  • Checksum: BE6E53FB21144F88
  • Sequence:
    • MSEAPRFFVG PEDTEINPGN YRHFFHHADE DDEEEDDSPP ERQIVVGICS MAKKSKSKPM 
KEILERISLF KYITVVVFEE EVILNEPVEN WPLCDCLISF HSKGFPLDKA VAYAKLRNPF 
VINDLNMQYL IQDRREVYSI LQAEGILLPR YAILNRDPNN PKECNLIEGE DHVEVNGEVF 
QKPFVEKPVS AEDHNVYIYY PTSAGGGSQR LFRKIGSRSS VYSPESNVRK TGSYIYEEFM 
PTDGTDVKVY TVGPDYAHAE ARKSPALDGK VERDSEGKEV RYPVILNARE KLIAWKVCLA 
FKQTVCGFDL LRANGQSYVC DVNGFSFVKN SMKYYDDCAK ILGNIVMREL APQFHIPWSI 
PLEAEDIPIV PTTSGTMMEL RCVIAVIRHG DRTPKQKMKM EVRHQKFFDL FEKCDGYKSG 
KLKLKKPKQL QEVLDIARQL LMELGQNNDS EIEENKPKLE QLKTVLEMYG HFSGINRKVQ 
LTYLPHGCPE TSSEEEDSRR EEPSLLLVLK WGGELTPAGR VQAEELGRAF RCMYPGGQGD 
YAGFPGCGLL RLHSTYRHDL KIYASDEGRV QMTAAAFAKG LLALEGELTP ILVQMVKSAN 
MNGLLDSDSD SLSSCQQRVK ARLHEILQKD RDFTAEDYEK LTPSGSISLI KSMHLIKNPV 
KTCDKVYSLI QSLTSQIRHR MEDPKSSDIQ LYHSETLELM LRRWSKLERD FKTKNGRYDI 
SKIPDIYDCI KYDVQHNGSL KLENTMELYR LSKALADIVI PQEYGITKAE KLEIAKGYCT 
PLVRKIRSDL QRTQDDDTVN KLHPVYSRGV LSPERHVRTR LYFTSESHVH SLLSILRYGA 
LCNTNDSQNE DGGMVKEMES KDEQWKRAMD YLNVVNELNY MTQIVIMLYE DPNKDLSSEE 
RFHVELHFSP GAKGCEEDKN LPSGYGYRPA SRENEGRRPF KIDNDDEPHT SKRDEVDRAV 
ILFKPMVSEP IHIHRKSPLP RSRKTATNDE ESPLSVSSPE GTGTWLHYTS GVGTGRRRRR 
SGEQITSSPV SPKSLAFTSS IFGSWQQVVS ENANYLRTPR TLVEQKQNPT VGSHCAGLFS 
TSVLGGSSSA PNLQDYARTH RKKLTSSGCI DDATRGSAVK RFSISFARHP TNEHLHLYRC 
WSVSSVEFLG SSGFELYSMV PSICPLETLH NALSLKQVDE FLASIASPSS DVPRKTAEIS 
STALRSSPIM RKKVSLNTYT PAKILPTPPA TLKSTKASSK PATSGPSSAV VPNTSSRKKN 
ITSKTETHEH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.