Details for: POFUT2

Gene ID: 23275

Symbol: POFUT2

Ensembl ID: ENSG00000186866

Description: protein O-fucosyltransferase 2

Associated with

Other Information

Genular Protein ID: 1440840698

Symbol: OFUT2_HUMAN

Name: GDP-fucose protein O-fucosyltransferase 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15233996

Title: The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development.

PubMed ID: 15233996

DOI: 10.1016/j.ygeno.2004.04.002

PubMed ID: 12966037

Title: A new superfamily of protein-O-fucosyltransferases, alpha2-fucosyltransferases, and alpha6-fucosyltransferases: phylogeny and identification of conserved peptide motifs.

PubMed ID: 12966037

DOI: 10.1093/glycob/cwg113

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11067851

Title: C-mannosylation and O-fucosylation of the thrombospondin type 1 module.

PubMed ID: 11067851

DOI: 10.1074/jbc.m008073200

PubMed ID: 16464858

Title: Two distinct pathways for O-fucosylation of epidermal growth factor-like or thrombospondin type 1 repeats.

PubMed ID: 16464858

DOI: 10.1074/jbc.m511974200

PubMed ID: 17395589

Title: O-fucosylation is required for ADAMTS13 secretion.

PubMed ID: 17395589

DOI: 10.1074/jbc.m700317200

PubMed ID: 17395588

Title: O-fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1/punctin-1 regulates secretion: implications for the ADAMTS superfamily.

PubMed ID: 17395588

DOI: 10.1074/jbc.m701065200

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 22588082

Title: Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation.

PubMed ID: 22588082

DOI: 10.1038/emboj.2012.143

Sequence Information:

  • Length: 429
  • Mass: 49976
  • Checksum: 36A4213D905AFFD1
  • Sequence:
  • MATLSFVFLL LGAVSWPPAS ASGQEFWPGQ SAADILSGAA SRRRYLLYDV NPPEGFNLRR 
    DVYIRIASLL KTLLKTEEWV LVLPPWGRLY HWQSPDIHQV RIPWSEFFDL PSLNKNIPVI 
    EYEQFIAESG GPFIDQVYVL QSYAEGWKEG TWEEKVDERP CIDQLLYSQD KHEYYRGWFW 
    GYEETRGLNV SCLSVQGSAS IVAPLLLRNT SARSVMLDRA ENLLHDHYGG KEYWDTRRSM 
    VFARHLREVG DEFRSRHLNS TDDADRIPFQ EDWMKMKVKL GSALGGPYLG VHLRRKDFIW 
    GHRQDVPSLE GAVRKIRSLM KTHRLDKVFV ATDAVRKEYE ELKKLLPEMV RFEPTWEELE 
    LYKDGGVAII DQWICAHARF FIGTSVSTFS FRIHEEREIL GLDPKTTYNR FCGDQEKACE 
    QPTHWKITY

Genular Protein ID: 2001613425

Symbol: S6FW71_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 212
  • Mass: 24413
  • Checksum: C9C3E0C720579655
  • Sequence:
  • MATLSFVFLL LGAVSWPPAS ASGQEFWPGQ SAADILSGAA SRRRYLLYDV NPPEGFNLRR 
    DVYIRIASLL KTLLKTEEWV LVLPPWGRLY HWQSPDIHQV RIPWSEFFDL PSLNKNIPVI 
    EYEQFIAGRR TACGVCFVVS QCSARDKESG GPFIDQVYVL QSYAEGWKEG TWEEKVDERP 
    CIDQLLYSQD KHEYYRCLLR LLPLPQRMVL GL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.