Details for: ADGRL3

Gene ID: 23284

Symbol: ADGRL3

Ensembl ID: ENSG00000150471

Description: adhesion G protein-coupled receptor L3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 4.95
    Marker Score: 3,259
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 4.41
    Marker Score: 20,421
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 3.84
    Marker Score: 51,082
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.7
    Marker Score: 4,612
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 3.55
    Marker Score: 1,592
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.24
    Marker Score: 69,254
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 3.04
    Marker Score: 8,682
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.95
    Marker Score: 4,949
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.92
    Marker Score: 58,090
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.85
    Marker Score: 21,855
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.82
    Marker Score: 42,207
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.72
    Marker Score: 103,267
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.63
    Marker Score: 3,023
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.62
    Marker Score: 10,848
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.56
    Marker Score: 6,138
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.46
    Marker Score: 90,671
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.39
    Marker Score: 1,293
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.36
    Marker Score: 9,109
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.24
    Marker Score: 1,338
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.2
    Marker Score: 20,665
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.16
    Marker Score: 2,058
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.16
    Marker Score: 2,669
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.08
    Marker Score: 127,993
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.07
    Marker Score: 866
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.93
    Marker Score: 18,340
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.88
    Marker Score: 16,174
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.71
    Marker Score: 466
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.68
    Marker Score: 3,408
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.65
    Marker Score: 2,554
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6
    Marker Score: 1,163
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.57
    Marker Score: 944
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.54
    Marker Score: 1,534
  • Cell Name: T cell (CL0000084)
    Fold Change: 1.5
    Marker Score: 2,585
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167,864
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.36
    Marker Score: 5,554
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 864
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.34
    Marker Score: 2,931
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.26
    Marker Score: 515
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.25
    Marker Score: 473
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.24
    Marker Score: 430
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.23
    Marker Score: 19,192
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.17
    Marker Score: 484
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.16
    Marker Score: 1,002
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.15
    Marker Score: 1,245
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4,799
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.09
    Marker Score: 500
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 1.06
    Marker Score: 310
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.03
    Marker Score: 6,162
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1
    Marker Score: 484
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 506
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.98
    Marker Score: 2,311
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,406
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.98
    Marker Score: 1,990
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 459
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.95
    Marker Score: 302
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.95
    Marker Score: 1,016
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.95
    Marker Score: 528
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,412
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,332
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 372
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.93
    Marker Score: 8,139
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.92
    Marker Score: 490
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,736
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 325
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.88
    Marker Score: 1,101
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.88
    Marker Score: 227
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,281
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.87
    Marker Score: 547
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.84
    Marker Score: 645
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.83
    Marker Score: 396
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.83
    Marker Score: 259
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 0.82
    Marker Score: 773
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.82
    Marker Score: 755
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.81
    Marker Score: 294
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 0.81
    Marker Score: 541
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,266
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 705
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.76
    Marker Score: 368
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.76
    Marker Score: 335
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.74
    Marker Score: 192
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.71
    Marker Score: 2,957
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.71
    Marker Score: 4,713
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 179
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 0.7
    Marker Score: 784
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.66
    Marker Score: 14,810
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.65
    Marker Score: 520
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.64
    Marker Score: 456
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.63
    Marker Score: 352
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.62
    Marker Score: 1,185
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.6
    Marker Score: 396
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 0.59
    Marker Score: 277
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.58
    Marker Score: 136
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.57
    Marker Score: 378
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.57
    Marker Score: 145
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 148
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.55
    Marker Score: 942
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.55
    Marker Score: 3,279
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.55
    Marker Score: 763
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.55
    Marker Score: 640

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular Localization:** ADGRL3 is primarily expressed in mature astrocytes, inhibitory interneurons, cardiac muscle cells, and epithelial cells of the alveolus in the lung. 2. **Protein Structure:** The ADGRL3 protein belongs to the ADGRL family, which consists of seven transmembrane receptors. The protein contains a characteristic seven-transmembrane domain structure, with a cytoplasmic tail and an extracellular domain. 3. **Signal Transduction:** ADGRL3 mediates its effects through the adenylate cyclase-activating g protein-coupled receptor signaling pathway, which regulates various cellular processes, including cell adhesion, migration, and neurotransmission. 4. **Cell Adhesion:** ADGRL3 plays a critical role in cell-cell adhesion via plasma-membrane adhesion molecules, facilitating the formation of cell-cell junctions and modulating the immune response. **Pathways and Functions:** 1. **Adenylate Cyclase-Activating G Protein-Coupled Receptor Signaling Pathway:** ADGRL3 activates the adenylate cyclase-activating g protein-coupled receptor signaling pathway, leading to the production of cyclic AMP (cAMP) and influencing various cellular processes, including cell adhesion, migration, and neurotransmission. 2. **Cell-Cell Adhesion via Plasma-Membrane Adhesion Molecules:** ADGRL3 mediates cell-cell adhesion via plasma-membrane adhesion molecules, facilitating the formation of cell-cell junctions and modulating the immune response. 3. **Neuron Migration and Synapse Assembly:** ADGRL3 is involved in the regulation of neuron migration and synapse assembly, which are critical processes in the development and maintenance of the nervous system. 4. **Cardiac Function:** ADGRL3 is expressed in cardiac muscle cells and plays a role in regulating cardiac function, including heart rate and contraction force. **Clinical Significance:** 1. **Neurological Disorders:** Mutations in the ADGRL3 gene have been associated with neurological disorders, including autism spectrum disorder and schizophrenia. 2. **Cardiovascular Disease:** ADGRL3 has been implicated in the regulation of cardiac function, and alterations in ADGRL3 expression may contribute to the development of cardiovascular disease. 3. **Immune System Dysregulation:** ADGRL3 plays a role in regulating the immune response, and dysregulation of ADGRL3 expression may contribute to immune system dysregulation and autoimmune diseases. 4. **Cancer:** ADGRL3 has been identified as a potential biomarker for cancer, with altered expression levels observed in various types of cancer, including breast, lung, and colon cancer. In conclusion, ADGRL3 is a multifaceted gene with far-reaching implications for our understanding of cellular behavior, immune system regulation, and neurological and cardiovascular disease. Further research is necessary to fully elucidate the functions of ADGRL3 and its role in human disease.

Genular Protein ID: 3316537392

Symbol: AGRL3_HUMAN

Name: Lectomedin-3

UniProtKB Accession Codes:

Q9HAR2 E9PE04 O94867 Q9NWK5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChEBI 4 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EMDB 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 14 Gene3D 5 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MEROPS 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 PANTHER 2 PDB 8 PDBsum 4 PRINTS 2 PRO 1 PROSITE 6 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 7 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 3 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniLectin 1 UniProtKB 2 VEuPathDB 1 eggNOG 3 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 9872452

Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9872452

DOI: 10.1093/dnares/5.5.277

PubMed ID: 26235030

Title: Structural basis of latrophilin-FLRT-UNC5 interaction in cell adhesion.

PubMed ID: 26235030

DOI: 10.1016/j.str.2015.06.024

PubMed ID: 21184580

Title: Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility.

PubMed ID: 21184580

DOI: 10.1002/ajmg.b.31141

Sequence Information:

  • Length: 1447
  • Mass: 161812
  • Checksum: 54B7E7DBE516447A
  • Sequence:
    • MWPSQLLIFM MLLAPIIHAF SRAPIPMAVV RRELSCESYP IELRCPGTDV IMIESANYGR 
TDDKICDSDP AQMENIRCYL PDAYKIMSQR CNNRTQCAVV AGPDVFPDPC PGTYKYLEVQ 
YECVPYKVEQ KVFLCPGLLK GVYQSEHLFE SDHQSGAWCK DPLQASDKIY YMPWTPYRTD 
TLTEYSSKDD FIAGRPTTTY KLPHRVDGTG FVVYDGALFF NKERTRNIVK FDLRTRIKSG 
EAIIANANYH DTSPYRWGGK SDIDLAVDEN GLWVIYATEQ NNGKIVISQL NPYTLRIEGT 
WDTAYDKRSA SNAFMICGIL YVVKSVYEDD DNEATGNKID YIYNTDQSKD SLVDVPFPNS 
YQYIAAVDYN PRDNLLYVWN NYHVVKYSLD FGPLDSRSGQ AHHGQVSYIS PPIHLDSELE 
RPSVKDISTT GPLGMGSTTT STTLRTTTLS PGRSTTPSVS GRRNRSTSTP SPAVEVLDDM 
TTHLPSASSQ IPALEESCEA VEAREIMWFK TRQGQIAKQP CPAGTIGVST YLCLAPDGIW 
DPQGPDLSNC SSPWVNHITQ KLKSGETAAN IARELAEQTR NHLNAGDITY SVRAMDQLVG 
LLDVQLRNLT PGGKDSAARS LNKAMVETVN NLLQPQALNA WRDLTTSDQL RAATMLLHTV 
EESAFVLADN LLKTDIVREN TDNIKLEVAR LSTEGNLEDL KFPENMGHGS TIQLSANTLK 
QNGRNGEIRV AFVLYNNLGP YLSTENASMK LGTEALSTNH SVIVNSPVIT AAINKEFSNK 
VYLADPVVFT VKHIKQSEEN FNPNCSFWSY SKRTMTGYWS TQGCRLLTTN KTHTTCSCNH 
LTNFAVLMAH VEVKHSDAVH DLLLDVITWV GILLSLVCLL ICIFTFCFFR GLQSDRNTIH 
KNLCISLFVA ELLFLIGINR TDQPIACAVF AALLHFFFLA AFTWMFLEGV QLYIMLVEVF 
ESEHSRRKYF YLVGYGMPAL IVAVSAAVDY RSYGTDKVCW LRLDTYFIWS FIGPATLIIM 
LNVIFLGIAL YKMFHHTAIL KPESGCLDNI KSWVIGAIAL LCLLGLTWAF GLMYINESTV 
IMAYLFTIFN SLQGMFIFIF HCVLQKKVRK EYGKCLRTHC CSGKSTESSI GSGKTSGSRT 
PGRYSTGSQS RIRRMWNDTV RKQSESSFIT GDINSSASLN REGLLNNARD TSVMDTLPLN 
GNHGNSYSIA SGEYLSNCVQ IIDRGYNHNE TALEKKILKE LTSNYIPSYL NNHERSSEQN 
RNLMNKLVNN LGSGREDDAI VLDDATSFNH EESLGLELIH EESDAPLLPP RVYSTENHQP 
HHYTRRRIPQ DHSESFFPLL TNEHTEDLQS PHRDSLYTSM PTLAGVAATE SVTTSTQTEP 
PPAKCGDAED VYYKSMPNLG SRNHVHQLHT YYQLGRGSSD GFIVPPNKDG TPPEGSSKGP 
AHLVTSL

Genular Protein ID: 3485213342

Symbol: E7EUP0_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EUP0

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 5 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 13 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 2 PROSITE 10 PROSITE-ProRule 1 Pfam 7 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1308
  • Mass: 146210
  • Checksum: 7539128B6D21FB1B
  • Sequence:
    • MWPSQLLIFM MLLAPIIHGG KHSERHPALA APLRHAERSP GGALPPRHLL QQPAAERTAA 
HRGQGPRGAT RGVRGPGAQG AQIAAQAFSR APIPMAVVRR ELSCESYPIE LRCPGTDVIM 
IESANYGRTD DKICDSDPAQ MENIRCYLPD AYKIMSQRCN NRTQCAVVAG PDVFPDPCPG 
TYKYLEVQYE CVPYKVEQKV FLCPGLLKGV YQSEHLFESD HQSGAWCKDP LQASDKIYYM 
PWTPYRTDTL TEYSSKDDFI AGRPTTTYKL PHRVDGTGFV VYDGALFFNK ERTRNIVKFD 
LRTRIKSGEA IIANANYHDT SPYRWGGKSD IDLAVDENGL WVIYATEQNN GKIVISQLNP 
YTLRIEGTWD TAYDKRSASN AFMICGILYV VKSVYEDDDN EATGNKIDYI YNTDQSKDSL 
VDVPFPNSYQ YIAAVDYNPR DNLLYVWNNY HVVKYSLDFG PLDSRSGQAH HGQVSYISPP 
IHLDSELERP SVKDISTTGP LGMGSTTTST TLRTTTLSPG RSTTPSVSGR RNRSTSTPSP 
AVEVLDDMTT HLPSASSQIP ALEESCEAVE AREIMWFKTR QGQIAKQPCP AGTIGVSTYL 
CLAPDGIWDP QGPDLSNCSS PWVNHITQKL KSGETAANIA RELAEQTRNH LNAGDITYSV 
RAMDQLVGLL DVQLRNLTPG GKDSAARSLN KLQKRERSCR AYVQAMVETV NNLLQPQALN 
AWRDLTTSDQ LRAATMLLHT VEESAFVLAD NLLKTDIVRE NTDNIKLEVA RLSTEGNLED 
LKFPENMGHG STIQLSANTL KQNGRNGEIR VAFVLYNNLG PYLSTENASM KLGTEALSTN 
HSVIVNSPVI TAAINKEFSN KVYLADPVVF TVKHIKQSEE NFNPNCSFWS YSKRTMTGYW 
STQGCRLLTT NKTHTTCSCN HLTNFAVLMA HVEVKHSDAV HDLLLDVITW VGILLSLVCL 
LICIFTFCFF RGLQSDRNTI HKNLCISLFV AELLFLIGIN RTDQPIACAV FAALLHFFFL 
AAFTWMFLEG VQLYIMLVEV FESEHSRRKY FYLVGYGMPA LIVAVSAAVD YRSYGTDKVC 
WLRLDTYFIW SFIGPATLII MLNVIFLGIA LYKMFHHTAI LKPESGCLDN INYEDNRPFI 
KSWVIGAIAL LCLLGLTWAF GLMYINESTV IMAYLFTIFN SLQGMFIFIF HCVLQKKVRK 
EYGKCLRTHC CSGKSTESSI GSGKTSGSRT PGRYSTGSQS RIRRMWNDTV RKQSESSFIT 
GDINSSASLN REPYRETSMG VKLNIAYQIG ASEQCQGYKC HGYSTTEW

Genular Protein ID: 4249257345

Symbol: E7ESV6_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7ESV6

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 5 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 13 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 2 PROSITE 10 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 7 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1299
  • Mass: 145060
  • Checksum: 5E25A32DC1FDD736
  • Sequence:
    • MWPSQLLIFM MLLAPIIHGG KHSERHPALA APLRHAERSP GGALPPRHLL QQPAAERTAA 
HRGQGPRGAT RGVRGPGAQG AQIAAQAFSR APIPMAVVRR ELSCESYPIE LRCPGTDVIM 
IESANYGRTD DKICDSDPAQ MENIRCYLPD AYKIMSQRCN NRTQCAVVAG PDVFPDPCPG 
TYKYLEVQYE CVPYKVEQKV FLCPGLLKGV YQSEHLFESD HQSGAWCKDP LQASDKIYYM 
PWTPYRTDTL TEYSSKDDFI AGRPTTTYKL PHRVDGTGFV VYDGALFFNK ERTRNIVKFD 
LRTRIKSGEA IIANANYHDT SPYRWGGKSD IDLAVDENGL WVIYATEQNN GKIVISQLNP 
YTLRIEGTWD TAYDKRSASN AFMICGILYV VKSVYEDDDN EATGNKIDYI YNTDQSKDSL 
VDVPFPNSYQ YIAAVDYNPR DNLLYVWNNY HVVKYSLDFG PLDSRSGQAH HGQVSYISPP 
IHLDSELERP SVKDISTTGP LGMGSTTTST TLRTTTLSPG RSTTPSVSGR RNRSTSTPSP 
AVEVLDDMTT HLPSASSQIP ALEESCEAVE AREIMWFKTR QGQIAKQPCP AGTIGVSTYL 
CLAPDGIWDP QGPDLSNCSS PWVNHITQKL KSGETAANIA RELAEQTRNH LNAGDITYSV 
RAMDQLVGLL DVQLRNLTPG GKDSAARSLN KLQKRERSCR AYVQAMVETV NNLLQPQALN 
AWRDLTTSDQ LRAATMLLHT VEESAFVLAD NLLKTDIVRE NTDNIKLEVA RLSTEGNLED 
LKFPENMGHG STIQLSANTL KQNGRNGEIR VAFVLYNNLG PYLSTENASM KLGTEALSTN 
HSVIVNSPVI TAAINKEFSN KVYLADPVVF TVKHIKQSEE NFNPNCSFWS YSKRTMTGYW 
STQGCRLLTT NKTHTTCSCN HLTNFAVLMA HVEVKHSDAV HDLLLDVITW VGILLSLVCL 
LICIFTFCFF RGLQSDRNTI HKNLCISLFV AELLFLIGIN RTDQPIACAV FAALLHFFFL 
AAFTWMFLEG VQLYIMLVEV FESEHSRRKY FYLVGYGMPA LIVAVSAAVD YRSYGTDKVC 
WLRLDTYFIW SFIGPATLII MLNVIFLGIA LYKMFHHTAI LKPESGCLDN IKSWVIGAIA 
LLCLLGLTWA FGLMYINEST VIMAYLFTIF NSLQGMFIFI FHCVLQKKVR KEYGKCLRTH 
CCSGKSTESS IGSGKTSGSR TPGRYSTGSQ SRIRRMWNDT VRKQSESSFI TGDINSSASL 
NREPYRETSM GVKLNIAYQI GASEQCQGYK CHGYSTTEW

Genular Protein ID: 512055834

Symbol: B7Z2G2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z2G2

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2

Sequence Information:

  • Length: 273
  • Mass: 30981
  • Checksum: 9AB48FE3077246F2
  • Sequence:
    • MLVEVFESEH SRRKYFYLVG YGMPALIVAV SAAVDYRSYG TDKVCWLRLD TYFIWSFIGP 
ATLIIMLNVI FLGIALYKMF HHTAILKPES GCLDNINYED NRPFIKSWVI GAIALLCLLG 
LTWAFGLMYI NESTVIMAYL FTIFNSLQGM FIFIFHCVLQ KKVRKEYGKC LRTHCCSGKS 
TESSIGSGKT SGSRTPGRYS TGSQSRIRRM WNDTVRKQSE SSFITGDINS SASLNREPYR 
ETSMGVKLNI AYQIGASEQC QGYKCHGYST TEW

Genular Protein ID: 514613203

Symbol: E7EUW2_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EUW2

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 5 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 13 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PRINTS 2 PROSITE 10 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 7 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1580
  • Mass: 176058
  • Checksum: 4F4AC074C803D304
  • Sequence:
    • MWPSQLLIFM MLLAPIIHGG KHSERHPALA APLRHAERSP GGALPPRHLL QQPAAERTAA 
HRGQGPRGAT RGVRGPGAQG AQIAAQAFSR APIPMAVVRR ELSCESYPIE LRCPGTDVIM 
IESANYGRTD DKICDSDPAQ MENIRCYLPD AYKIMSQRCN NRTQCAVVAG PDVFPDPCPG 
TYKYLEVQYE CVPYKVEQKV FLCPGLLKGV YQSEHLFESD HQSGAWCKDP LQASDKIYYM 
PWTPYRTDTL TEYSSKDDFI AGRPTTTYKL PHRVDGTGFV VYDGALFFNK ERTRNIVKFD 
LRTRIKSGEA IIANANYHDT SPYRWGGKSD IDLAVDENGL WVIYATEQNN GKIVISQLNP 
YTLRIEGTWD TAYDKRSASN AFMICGILYV VKSVYEDDDN EATGNKIDYI YNTDQSKDSL 
VDVPFPNSYQ YIAAVDYNPR DNLLYVWNNY HVVKYSLDFG PLDSRSGQAH HGQVSYISPP 
IHLDSELERP SVKDISTTGP LGMGSTTTST TLRTTTLSPG RSTTPSVSGR RNRSTSTPSP 
AVEVLDDMTT HLPSASSQIP ALEESCEAVE AREIMWFKTR QGQIAKQPCP AGTIGVSTYL 
CLAPDGIWDP QGPDLSNCSS PWVNHITQKL KSGETAANIA RELAEQTRNH LNAGDITYSV 
RAMDQLVGLL DVQLRNLTPG GKDSAARSLN KLQKRERSCR AYVQAMVETV NNLLQPQALN 
AWRDLTTSDQ LRAATMLLHT VEESAFVLAD NLLKTDIVRE NTDNIKLEVA RLSTEGNLED 
LKFPENMGHG STIQLSANTL KQNGRNGEIR VAFVLYNNLG PYLSTENASM KLGTEALSTN 
HSVIVNSPVI TAAINKEFSN KVYLADPVVF TVKHIKQSEE NFNPNCSFWS YSKRTMTGYW 
STQGCRLLTT NKTHTTCSCN HLTNFAVLMA HVEVKHSDAV HDLLLDVITW VGILLSLVCL 
LICIFTFCFF RGLQSDRNTI HKNLCISLFV AELLFLIGIN RTDQPIACAV FAALLHFFFL 
AAFTWMFLEG VQLYIMLVEV FESEHSRRKY FYLVGYGMPA LIVAVSAAVD YRSYGTDKVC 
WLRLDTYFIW SFIGPATLII MLNVIFLGIA LYKMFHHTAI LKPESGCLDN INYEDNRPFI 
KSWVIGAIAL LCLLGLTWAF GLMYINESTV IMAYLFTIFN SLQGMFIFIF HCVLQKKVRK 
EYGKCLRTHC CSGKSTESSI GSGKTSGSRT PGRYSTGSQS RIRRMWNDTV RKQSESSFIT 
GDINSSASLN RGAMANHLIS NALLRPHGTN NPYNTLLGEP AVCNNPSVSM YNAQEGLLNN 
ARDTSVMDTL PLNGNHGNSY SIASGEYLSN CVQIIDRGYN HNETALEKKI LKELTSNYIP 
SYLNNHERSS EQNRNLMNKL VNNLGSGRED DAIVLDDATS FNHEESLGLE LIHEESDAPL 
LPPRVYSTEN HQPHHYTRRR IPQDHSESFF PLLTNEHTED LQSPHRDSLY TSMPTLAGVA 
ATESVTTSTQ TEPPPAKCGD AEDVYYKSMP NLGSRNHVHQ LHTYYQLGRG SSDGFIVPPN 
KDGTPPEGSS KGPAHLVTSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.