Details for: DMXL2

Gene ID: 23312

Symbol: DMXL2

Ensembl ID: ENSG00000104093

Description: Dmx like 2

Associated with

Other Information

Genular Protein ID: 3861097610

Symbol: DMXL2_HUMAN

Name: DmX-like protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11809763

Title: Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family.

PubMed ID: 11809763

DOI: 10.1074/jbc.c100730200

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25248098

Title: Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.

PubMed ID: 25248098

DOI: 10.1371/journal.pbio.1001952

PubMed ID: 27657680

Title: A dominant variant in DMXL2 is linked to nonsyndromic hearing loss.

PubMed ID: 27657680

DOI: 10.1038/gim.2016.142

PubMed ID: 31688942

Title: Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course.

PubMed ID: 31688942

DOI: 10.1093/brain/awz326

PubMed ID: 30237576

Title: Autozygome and high throughput confirmation of disease genes candidacy.

PubMed ID: 30237576

DOI: 10.1038/s41436-018-0138-x

Sequence Information:

  • Length: 3036
  • Mass: 339641
  • Checksum: 25E9B1D05C69882C
  • Sequence:
  • MHLHQVLTGA VNPGDNCYSV GSVGDVPFTA YGSGCDIVIL ANDFECVQII PGAKHGNIQV 
    SCVECSNQQG RIAASYGNAV CIFEPLGINS HKRNCQLKCQ WLKTGQFFLS SVTYNLAWDP 
    QDNRLLTATD SIQLWAPPGD DILEEEEEID NTVPPVLNDW KCVWQCKTSV SVHLMEWSPD 
    GEYFATAGKD DCLLKVWYPM TGWKSSIIPQ DHHEVKRRQS STQFSFVYLA HPRAVTGFSW 
    RKTSKYMPRG SVCNVLLTSC HDGVCRLWAE TLLPEDCLLG EQICETTTSS IASSLSHAGR 
    HKDRIQHALE TIHHLKNLRK GQRRSSVLVT HAELMPDQTA MHEVQRHISH HANALCHFHI 
    AASINPATDI PNVLVGTAFN VDDGNGGFVV HWLNNKEFHF TSSTEVFMHQ LRKLSDKQVD 
    HENDDADRED EEHSQEDRER GLHMKLDHDL SLDRESEAGT GSSEHEDGER EGSPRTYSRL 
    SVPMPLPTVL LDRKIETLLT EWNKNPDMLF TIHPVDGTFL VWHVKYLDEY NPGIFRQVQV 
    SFSSRIPVAF PSGDASSLSK NIMMYACINA TKDSHHTLLH QEGMSVGSPH GSQPHSRSHS 
    THMNILAPTV MMISKHIDGS LNQWAVTFAD KSAFTTVLTV SHKFRYCGHR FHLNDLACHS 
    VLPLLLTSSH HNALLTPELD CQWDSDNKLS RLMDPVKHIK GSSKQPLRNA ATRTFHDPNA 
    IYSELILWRV DPIGPLSYTG GVSELARINS LHTSAFSNVA WLPTLIPSYC LGTYCNSASA 
    CFVASDGKNL RLYQAVVDAR KLLDELSDPE SSKLIGEVFN IVSQQSTARP GCIIELDAIT 
    NQCGSNTQLL HVFQEDFIIG YKPHKEDMEK KETEIFFQPS QGYRPPPFSE KFFLVVIEKD 
    SNNNSILHMW HLHLKSVQAC LAKASEGASS ESLLSVPGQK NVDSSPETSP SVSPMPHSSS 
    IANLQTASKL ILSSRLVYSQ PLDLPESVEV IRATPSAGHL SSSSIYPVCL APYLVVTTCS 
    DNKVRFWKCC MEANPECNKS DEKEIYHWKR WPLMNDEGED NSSTVSIVGR PVAVSCSYTG 
    RLAVAYKQPI HHNGFVSKEF SMHVCIFECE STGGSEWVLE QTIHLDDLVK VGSVLDSRVS 
    VDSNLFVYSK SDALLSKDRY LIPNIKHLVH LDWVSKEDGS HILTVGVGAN IFMYGRLSGI 
    VTEQTNSKDG VAVITLPLGG SIKQGVKSRW VLLRSIDLVS SVDGTPSLPV SLSWVRDGIL 
    VVGMDCEMHV YAQWKHAVKF GDTEADSSNA EEAAMQDHST FKSNMLARKS VVEGTAISDD 
    VFCSPTVIQD GGLFEAAHVL SPTLPQYHPT QLLELMDLGK VRRAKAILSH LVKCIAGEVA 
    IVRDPDAGEG TKRHLSRTIS VSGSTAKETV TVGKDGTRDY TEIDSIPPLP LYALLAADQD 
    TSYRISEEST KIPQSYEDQT VSQPEDQYSE LFQIQDIPTD DIDLEPEKRE NKSKVINLSQ 
    YGPAYFGQEH ARVLSSHLMH SSLPGLTRLE QMFLVALADT VATTSTELDE SRDKSCSGRD 
    TLDECGLRYL LAMRLHTCLL TSLPPLYRVQ LLHQGVSTCH FAWAFHSEAE EELINMIPAI 
    QRGDPQWSEL RAMGIGWWVR NINTLRRCIE KVAKASFQRN NDALDAALFY LSMKKKAVVW 
    GLFRSQHDEK MTTFFSHNFN EDRWRKAALK NAFSLLGKQR FEQSAAFFLL AGSLKDAIEV 
    CLEKMEDIQL AMVIARLYES EFETSSTYIS ILNQKILGCQ KDGSGFSCKR LHPDPFLRSL 
    AYWVMKDYTR ALDTLLEQTP KEDDEHQVII KSCNPVAFSF YNYLRTHPLL IRRNLASPEG 
    TLATLGLKTE KNFVDKINLI ERKLFFTTAN AHFKVGCPVL ALEVLSKIPK VTKTSALSAK 
    KDQPDFISHR MDDVPSHSKA LSDGNGSSGI EWSNVTSSQY DWSQPIVKVD EEPLNLDWGE 
    DHDSALDEEE DDAVGLVMKS TDAREKDKQS DQKASDPNML LTPQEEDDPE GDTEVDVIAE 
    QLKFRACLKI LMTELRTLAT GYEVDGGKLR FQLYNWLEKE IAALHEICNH ESVIKEYSSK 
    TYSKVESDLL DQEEMVDKPD IGSYERHQIE RRRLQAKREH AERRKSWLQK NQDLLRVFLS 
    YCSLHGAQGG GLASVRMELK FLLQESQQET TVKQLQSPLP LPTTLPLLSA SIASTKTVIA 
    NPVLYLNNHI HDILYTIVQM KTPPHPSIED VKVHTLHSLA ASLSASIYQA LCDSHSYSQT 
    EGNQFTGMAY QGLLLSDRRR LRTESIEEHA TPNSSPAQWP GVSSLINLLS SAQDEDQPKL 
    NILLCEAVVA VYLSLLIHAL ATNSSSELFR LAAHPLNNRM WAAVFGGGVK LVVKPRRQSE 
    NISAPPVLSE DIDKHRRRFN MRMLVPGRPV KDATPPPVPA ERPSYKEKFI PPELSMWDYF 
    VAKPFLPLSD SGVIYDSDES IHSDEEDDAF FSDTQIQEHQ DPNSYSWALL HLTMVKLALH 
    NVKNFFPIAG LEFSELPVTS PLGIAVIKNL ENWEQILQEK MDQFEGPPPN YINTYPTDLS 
    VGAGPAILRN KAMLEPENTP FKSRDSSAFP VKRLWHFLVK QEVLQETFIR YIFTKKRKQS 
    EVEADLGYPG GKAKVIHKES DMIMAFSVNK ANCNEIVLAS THDVQELDVT SLLACQSYIW 
    IGEEYDRESK SSDDVDYRGS TTTLYQPSAT SYSASQVHPP SSLPWLGTGQ TSTGASVLMK 
    RNLHNVKRMT SHPVHQYYLT GAQDGSVRMF EWTRPQQLVC FRQAGNARVT RLYFNSQGNK 
    CGVADGEGFL SIWQVNQTAS NPKPYMSWQC HSKATSDFAF ITSSSLVATS GHSNDNRNVC 
    LWDTLISPGN SLIHGFTCHD HGATVLQYAP KQQLLISGGR KGHVCIFDIR QRQLIHTFQA 
    HDSAIKALAL DPYEEYFTTG SAEGNIKVWR LTGHGLIHSF KSEHAKQSIF RNIGAGVMQI 
    DIIQGNRLFS CGADGTLKTR VLPNAFNIPN RILDIL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.