Details for: SZT2

Gene ID: 23334

Symbol: SZT2

Ensembl ID: ENSG00000198198

Description: SZT2 subunit of KICSTOR complex

Associated with

Other Information

Genular Protein ID: 392413184

Symbol: SZT2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15028280

Title: Bridging expressed sequence alignments through targeted cDNA sequencing.

PubMed ID: 15028280

DOI: 10.1016/j.ygeno.2003.07.003

PubMed ID: 10737800

Title: Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PubMed ID: 10737800

DOI: 10.1073/pnas.97.7.3491

PubMed ID: 9455484

Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PubMed ID: 9455484

DOI: 10.1093/dnares/4.5.345

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 20045724

Title: A novel giant peroxisomal superoxide dismutase motif-containing protein.

PubMed ID: 20045724

DOI: 10.1016/j.freeradbiomed.2009.12.023

PubMed ID: 23932106

Title: Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum.

PubMed ID: 23932106

DOI: 10.1016/j.ajhg.2013.07.005

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28199306

Title: KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

PubMed ID: 28199306

DOI: 10.1038/nature21423

PubMed ID: 28199315

Title: SZT2 dictates GATOR control of mTORC1 signalling.

PubMed ID: 28199315

DOI: 10.1038/nature21378

PubMed ID: 24324832

Title: An amino acid deletion inSZT2 in a family with non-syndromic intellectual disability.

PubMed ID: 24324832

DOI: 10.1371/journal.pone.0082810

Sequence Information:

  • Length: 3432
  • Mass: 378029
  • Checksum: E65E415FA8C55BC1
  • Sequence:
  • MASERPEPEV EEAGQVFLLM KKDYRISRNV RLAWFLSHLH QTVQATPQEM LLQSEQELEV 
    LSVLPPGWQP DEPVVPRPFL LVPSTRVTFL AWQYRFVIEL DLSPSTGIVD DSTGEILFDE 
    VFHALSRCLG GLLRPFRVPG SCIDFQPEIY VTIQAYSSII GLQSHQVLVQ GCLLDPSQRE 
    VFLQQIYEQL CLFEDKVATM LQQQYDPQSQ AEDQSPDSGD LLGRKVGVSM VTADLGLVSM 
    IRQGILALQL LPSNSSAGII VITDGVTSVP DVAVCETLLN QLRSGTVACS FVQVGGVYSY 
    DCSFGHVPNV ELMKFIAMAT FGSYLSTCPE PEPGNLGLTV YHRAFLLYSF LRSGEALNPE 
    YYCGSQHRLF NEHLVSASSN PALALRRKKH TEKEVPADLV STVSVRLREG YSVREVTLAK 
    GGSQLEVKLV LLWKHNMRIE YVAMAPWPLE PEGPRVTRVE VTMEGGYDIL HDVSCALRQP 
    IRSLYRTHVI RRFWNTLQSI NQTDQMLAHL QSFSSVPEHF TLPDSTKSGV PLFYIPPGST 
    TPVLSLQPSG SDSSHAQFAA YWKPVLSMDA NSWQRWLHMH RLVLILEHDT PIPKHLHTPG 
    SNGRYSTIQC RISHSSLTSL LRDWSSFVLV EGYSYVKLLS SAPDQPPNSF YMVRIISKAP 
    CMVLRLGFPI GTPAPARHKI VSGLREEILR LRFPHRVQSK EPTPKVKRKG LGGAGGGSSP 
    SKSPPVLGPQ QALSDRPCLV VLHKPLDKLL IRYEKLPLDY RAPFLLTLEP PGPLPLVSGR 
    SASSSLASLS RYLYHQRWLW SVPSGLAPAL PLSAIAQLLS ILTEVRLSEG FHFACSGEGI 
    INMVLELPIQ NEPPGQAAAE EKHTCVVQYI LFPPHSTSTK DSFSTDDDND VEVEALEGDS 
    ELNLVTEVWV EPQYGRVGPG PGIWKHLQDL TYSEIPQALH PRDAACIGSM LSFEYLIQLC 
    QSKEWGPLPP EPRVSDGLDQ GGDTCVHEIP FHFDLMGLLP QCQQLQMFFL LLAREPEGVP 
    FAEGSCPAND MVLCLLHSCL GQELSDREIP LTPVDQAAFL SEVLRRTCHV PGAEGPLLGV 
    HGIPKEQAVG STQATGDSAF TSLSVGLPET LKPLISAQPP QWRCYARLVN PQHVFLTFLP 
    ATFSDVQRLA ACGLEGPPQE ETKPKFGDWS GAPSLKDLGG TGIKATKSHV PVLSVTLASD 
    NAQNQGELSP PFRRDLQAYA GRQASQTESA DGPRTRCPVY IYSCSLEALR EQMVGMQPPQ 
    APRDLIFRTQ FLDHPSPSSA WMEPRYKEAA NHCALLQEHA QRCYVRGLFR SLQQAQSVTS 
    QDLLTAVDAC EELLQEIDIT PFLLALCGHT WGLPHAPPSP GPLSPGPFSS SMEEGAEPRE 
    RAILASESSI ETEDLSEPEF QSTRVPGIPD PGPEISLTDV CQLRGEAHGA LHSVIQEKFL 
    EISRLHFRTV PSNPHYFFYC PPSSRREDEG PRDTVDRKIS DLEFSEAELM GEEGDTSACC 
    VVTESDPELE VEYRESRESD LGPAGLDSAS LSDVDTVNPD EDSFSILGGD SPTGPESFLH 
    DLPPLFLHLT CSVRLRGQHS SVPVCSLPTC LGQVLSSLEG PPVGGRVPLR DLSVTLDVFM 
    LTLPLEVELP TASDPQHHRS TSESSASFPR SPGQPSSLRS DDGLGPPLPP PEEERHPGLS 
    NLATPHRLAI ETTMNEIRWL LEDEMVGALR RGGIPQSPAL HRAAAHIHSS PGRSTCLRQT 
    LPLSFVFGPE RSLTQFKEEF RRLHLPGHVL LEDPDSGFFF VAAGQQPGGS HGEPSSAAWA 
    WHSHEDRAEG IEGETLTASP QAPGSPEDSE GVPLISLPRV PQGGSQPGPS RGLSLMSSQG 
    SVDSDHLGYD GGSSGSDSEG PNDTLGEKAP FTLRTPPGPA PPQPSLSGLP GPCLPDFWLI 
    VRVLQDRVEV YAHARSLIRE DGGPGTECRH LQQLLVRRVG EICREVNQRL LLQDLHDSHV 
    CNSLLVAESE EDLWRSETPF HSRQRAPLPS DDYAADESCA PRGYLAATMQ FVPGHFSCDV 
    VWGTVIRVHS RLKMGPSMGV SRAIQALRSV LNAFSVVNRK NMFVYQERAT KAVYYLRLLE 
    TSCSDRPWKG DALPPSLALS RSQEPIYSEE ASGPRSPLDM VSSRSSDAAR PVGQVDRHIQ 
    LLVHGVGQAG PEITDELVRV LCRRLDEATL DVITVMLVRN CKLTPADVEF IQPPGSLPSE 
    VLHLALPTSC RPWLPALAWY LRQNLLIFLH SPKYTDSNSR NHFQHPLPPQ GGLPDLDIYL 
    YNKPGGQGTG GKGVACITLA FVDEGGAPLS LALWPPSSPG PPDPLREEEF EQLTQVIRCP 
    VVVDSSSAQN GAPRLRLDVW EKGNISIVQL EEKLRGAARQ ALADAIIELQ LLPASLCTED 
    TPTGSLRNGS LETKSSAGRA STFPPAPVPG EPVTPPSKAG RRSFWDMLSK TECGDLGSPK 
    TTDDIVLDRP EDTRGRRRHK TESVRTPGGA ERAPGSDSGA QRQKRRTTQL EEGEVGTLHP 
    VFARVAQRWM EFMVQIGCAS VSRSSAHMVS RFLLPSILSE FTALVTSMAG DTSVRIFEQH 
    LGSEPEIFGP CSPGQLGPSP RPAAERHLLL LGRNFLQWRR PTQQAAKAMQ RFEPGGDGSS 
    GRNAPRQRLL LLEVVDKKLQ LLTYNWAPDL GAALGRALVR LVQWQNARAH LIFCLLSQKL 
    GLFHHYGQLD FPVRDEKEPN PFLLPTMEVE TLIRSASPPL SREQGRLSGS SRGGGPLPLD 
    TFPFDEALRD ITAARPSSVL GPVPRPPDPV TYHGQQFLEI KMAERRELER QMKMENLFVT 
    WQQRSTPATM PISAGELETL KQSSRLVHYC ATAMLFDPAA WLHGPPETSG PPDGQRRHRP 
    ESGSGSREAP TSCESLDVSP PGAREEPWLK ELSLAFLQQY VQYLQSIGFV LVPLRPPSPA 
    RSTSRPRAMA ILGTEGRGSF SCPKTKTDGS PKSTSSPVTT YHLQRALPGG IILMELAFQG 
    CYFCVKQFAL ECSRIPMGQA VNSQLSMLFT EECDKVRDLM HVHSFSYDFH LRLVHQHVLG 
    AHLVLRHGYH LTTFLRHFLA HHPDGPHFGR NHIYQGTLEL PTPLIAAHQL YNYVADHASS 
    YHMKPLRMAR PGGPEHNEYA LVSAWHSSGS YLDSEGLRHQ DDFDVSLLVC HCAAPFEEQG 
    EAERHVLRLQ FFVVLTSQRE LFPRLTADMR RFRKPPRLPP EPEAPGSSAG SPGEASGLIL 
    APGPAPLFPP LAAEVGMARA RLAQLVRLAG GHCRRDTLWK RLFLLEPPGP DRLRLGGRLA 
    LAELEELLEA VHAKSIGDID PQLDCFLSMT VSWYQSLIKV LLSRFPQSCR HFQSPDLGTQ 
    YLVVLNQKFT DCFVLVFLDS HLGKTSLTVV FREPFPVQPQ DSESPPAQLV STYHHLESVI 
    NTACFTLWTR LL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.