Details for: SUN1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.42
Marker Score: 5,322 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.42
Marker Score: 1,407 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 2.31
Marker Score: 9,641 - Cell Name: ciliated cell (CL0000064)
Fold Change: 2.23
Marker Score: 7,657 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.19
Marker Score: 2,952 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.98
Marker Score: 42,263 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.97
Marker Score: 74,735 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.96
Marker Score: 8,218 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.96
Marker Score: 15,016 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.95
Marker Score: 16,942 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.95
Marker Score: 38,753 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.93
Marker Score: 1,316 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.92
Marker Score: 2,320 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.86
Marker Score: 7,210 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.84
Marker Score: 27,585 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.84
Marker Score: 17,352 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.84
Marker Score: 113,410 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.84
Marker Score: 67,948 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.77
Marker Score: 7,336 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.76
Marker Score: 16,762 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.74
Marker Score: 1,018 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.72
Marker Score: 14,783 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.7
Marker Score: 712 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.69
Marker Score: 1,942 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.66
Marker Score: 1,586 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.66
Marker Score: 17,139 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.61
Marker Score: 36,081 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.61
Marker Score: 1,723 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.6
Marker Score: 1,259 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.58
Marker Score: 916 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.57
Marker Score: 938 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.57
Marker Score: 2,307 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.56
Marker Score: 53,223 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.55
Marker Score: 490 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.54
Marker Score: 1,620 - Cell Name: basal cell (CL0000646)
Fold Change: 1.54
Marker Score: 1,986 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 1.53
Marker Score: 2,914 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 1.51
Marker Score: 717 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.49
Marker Score: 2,301 - Cell Name: neuron (CL0000540)
Fold Change: 1.48
Marker Score: 6,044 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.48
Marker Score: 992 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 1.47
Marker Score: 557 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.47
Marker Score: 9,373 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.45
Marker Score: 423 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.44
Marker Score: 1,629 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.44
Marker Score: 49,802 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.43
Marker Score: 3,379 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.43
Marker Score: 448 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.42
Marker Score: 1,571 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.38
Marker Score: 6,802 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.37
Marker Score: 3,337 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.36
Marker Score: 765 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.36
Marker Score: 392 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.33
Marker Score: 6,167 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 1.32
Marker Score: 649 - Cell Name: PP cell (CL0000696)
Fold Change: 1.31
Marker Score: 296 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.31
Marker Score: 2,622 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.31
Marker Score: 1,175 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.29
Marker Score: 353 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.29
Marker Score: 1,871 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.27
Marker Score: 737 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.26
Marker Score: 506 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.24
Marker Score: 19,471 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.23
Marker Score: 2,319 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 1.23
Marker Score: 286 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.23
Marker Score: 1,326 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.23
Marker Score: 1,277 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.23
Marker Score: 304 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.22
Marker Score: 3,272 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.22
Marker Score: 387 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 1.22
Marker Score: 293 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.22
Marker Score: 2,341 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 1.21
Marker Score: 1,094 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.21
Marker Score: 638 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.2
Marker Score: 1,042 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.18
Marker Score: 1,111 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.18
Marker Score: 572 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.18
Marker Score: 614 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 1.16
Marker Score: 828 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.16
Marker Score: 4,480 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.16
Marker Score: 334 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.14
Marker Score: 1,641 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.14
Marker Score: 2,023 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.13
Marker Score: 9,956 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.11
Marker Score: 358 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 1.11
Marker Score: 376 - Cell Name: pulmonary ionocyte (CL0017000)
Fold Change: 1.11
Marker Score: 679 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.1
Marker Score: 1,375 - Cell Name: club cell (CL0000158)
Fold Change: 1.1
Marker Score: 1,288 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.1
Marker Score: 253 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 1.1
Marker Score: 1,182 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.1
Marker Score: 1,176 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.09
Marker Score: 526 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.08
Marker Score: 4,155 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.08
Marker Score: 414 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.08
Marker Score: 1,141 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 1.08
Marker Score: 679 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.07
Marker Score: 7,993 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.06
Marker Score: 978 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.05
Marker Score: 492
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2762682618
Symbol: SUN1_HUMAN
Name: Protein unc-84 homolog A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9872452
Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9872452
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10375507
Title: UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development.
PubMed ID: 10375507
PubMed ID: 12958361
Title: Nuclear membrane proteins with potential disease links found by subtractive proteomics.
PubMed ID: 12958361
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18039933
Title: Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3.
PubMed ID: 18039933
PubMed ID: 17132086
Title: Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome.
PubMed ID: 17132086
PubMed ID: 16445915
Title: Nuclear envelope localization of human UNC84A does not require nuclear lamins.
PubMed ID: 16445915
PubMed ID: 17631499
Title: Histone acetyltransferase hALP and nuclear membrane protein hsSUN1 function in de-condensation of mitotic chromosomes.
PubMed ID: 17631499
PubMed ID: 18845190
Title: Sun1 forms immobile macromolecular assemblies at the nuclear envelope.
PubMed ID: 18845190
PubMed ID: 18396275
Title: Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.
PubMed ID: 18396275
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19933576
Title: Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.
PubMed ID: 19933576
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 27956467
Title: LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining.
PubMed ID: 27956467
PubMed ID: 28716842
Title: Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.
PubMed ID: 28716842
PubMed ID: 24375709
Title: Contribution of SUN1 mutations to the pathomechanism in muscular dystrophies.
PubMed ID: 24375709
DOI: 10.1002/humu.22504
Sequence Information:
- Length: 785
- Mass: 87110
- Checksum: 1099A50C9540ECF5
- Sequence:
MDFSRLHMYS PPQCVPENTG YTYALSSSYS SDALDFETEH KLDPVFDSPR MSRRSLRLAT TACTLGDGEA VGADSGTSSA VSLKNRAART TKQRRSTNKS AFSINHVSRQ VTSSGVSHGG TVSLQDAVTR RPPVLDESWI REQTTVDHFW GLDDDGDLKG GNKAAIQGNG DVGAAAATAH NGFSCSNCSM LSERKDVLTA HPAAPGPVSR VYSRDRNQKC YFLLQILRRI GAVGQAVSRT AWSALWLAVV APGKAASGVF WWLGIGWYQF VTLISWLNVF LLTRCLRNIC KFLVLLIPLF LLLAGLSLRG QGNFFSFLPV LNWASMHRTQ RVDDPQDVFK PTTSRLKQPL QGDSEAFPWH WMSGVEQQVA SLSGQCHHHG ENLRELTTLL QKLQARVDQM EGGAAGPSAS VRDAVGQPPR ETDFMAFHQE HEVRMSHLED ILGKLREKSE AIQKELEQTK QKTISAVGEQ LLPTVEHLQL ELDQLKSELS SWRHVKTGCE TVDAVQERVD VQVREMVKLL FSEDQQGGSL EQLLQRFSSQ FVSKGDLQTM LRDLQLQILR NVTHHVSVTK QLPTSEAVVS AVSEAGASGI TEAQARAIVN SALKLYSQDK TGMVDFALES GGGSILSTRC SETYETKTAL MSLFGIPLWY FSQSPRVVIQ PDIYPGNCWA FKGSQGYLVV RLSMMIHPAA FTLEHIPKTL SPTGNISSAP KDFAVYGLEN EYQEEGQLLG QFTYDQDGES LQMFQALKRP DDTAFQIVEL RIFSNWGHPE YTCLYRFRVH GEPVK
Genular Protein ID: 920546228
Symbol: A0A8I5G938_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12853948
Sequence Information:
- Length: 682
- Mass: 76403
- Checksum: CEEE24E27B0B6069
- Sequence:
MDFSRLHMYS PPQCVPENTG YTYALSSSYS SDALDFETEH KLDPVFDSPR MSRRSLRLAT TACTLGDGEA VGADSGTSSA VSLKNRAART TKQRRSTNKS AFSINHVSRQ VTSSGVSHGG TVSLQDAVTR RPPVLDESWI REQTTVDHFW GKAASGVFWW LGIGWYQFVT LISWLNVFLL TRCLRNICKF LVLLIPLFLL LGLSLRGQGN FFSFLPVLNW ASMHRTQRVD DPQDVFKPTT SRLKQPLQGD SEAFPWHWMS GVEQQVASLS GQCHHHGENL RELTTLLQKL QARVDQMEGG AAGPSASVRD AVGQPPRETD FMAFHQEHEV RMSHLEDILG KLREKSEAIQ KELEQTKQKT ISAVGEQLLP TVEHLQLELD QLKSELSSWR HVKTGCETVD AVQERVDVQV REMVKLLFSE DQQGGSLEQL LQRFSSQFVS KGDLQTMLRD LQLQILRNVT HHVSVTKQLP TSEAVVSAVS EAGASGITEA QARAIVNSAL KLYSQDKTGM VDFALESGGG SILSTRCSET YETKTALMSL FGIPLWYFSQ SPRVVIQPDI YPGNCWAFKG SQGYLVVRLS MMIHPAAFTL EHIPKTLSPT GNISSAPKDF AVYGLENEYQ EEGQLLGQFT YDQDGESLQM FQALKRPDDT AFQIVELRIF SNWGHPEYTC LYRFRVHGEP VK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.