Details for: VPS8

Gene ID: 23355

Symbol: VPS8

Ensembl ID: ENSG00000156931

Description: VPS8 subunit of CORVET complex

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.93
    Marker Score: 65,514
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.33
    Marker Score: 2,577
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.18
    Marker Score: 43,425
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.18
    Marker Score: 5,466
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.11
    Marker Score: 45,047
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.11
    Marker Score: 4,625
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.07
    Marker Score: 15,847
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.05
    Marker Score: 77,748
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.04
    Marker Score: 75,380
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.99
    Marker Score: 18,733
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.97
    Marker Score: 1,151
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.94
    Marker Score: 2,342
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.91
    Marker Score: 117,594
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.91
    Marker Score: 28,497
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.87
    Marker Score: 7,743
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.86
    Marker Score: 7,566
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.83
    Marker Score: 7,087
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.83
    Marker Score: 18,928
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.83
    Marker Score: 765
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.81
    Marker Score: 17,212
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.8
    Marker Score: 2,427
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.8
    Marker Score: 60,765
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.76
    Marker Score: 8,131
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.75
    Marker Score: 15,015
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.74
    Marker Score: 7,276
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.68
    Marker Score: 1,276
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.66
    Marker Score: 824
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.64
    Marker Score: 479
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.61
    Marker Score: 2,698
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.58
    Marker Score: 1,963
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.53
    Marker Score: 2,358
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.52
    Marker Score: 887
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.52
    Marker Score: 1,748
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.51
    Marker Score: 4,296
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.5
    Marker Score: 2,890
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.38
    Marker Score: 3,312
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.38
    Marker Score: 1,062
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.38
    Marker Score: 376
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.36
    Marker Score: 809
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.35
    Marker Score: 425
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.29
    Marker Score: 748
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.29
    Marker Score: 678
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.29
    Marker Score: 465
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.26
    Marker Score: 401
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.26
    Marker Score: 872
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.24
    Marker Score: 1,408
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.21
    Marker Score: 18,984
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.19
    Marker Score: 19,109
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.18
    Marker Score: 452
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.16
    Marker Score: 1,247
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.14
    Marker Score: 2,694
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.14
    Marker Score: 2,324
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.13
    Marker Score: 20,105
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.11
    Marker Score: 1,377
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.11
    Marker Score: 1,057
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.11
    Marker Score: 960
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.11
    Marker Score: 621
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.09
    Marker Score: 608
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.09
    Marker Score: 969
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.09
    Marker Score: 313
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.03
    Marker Score: 5,400
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.02
    Marker Score: 569
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,695
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1
    Marker Score: 368
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,920
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.99
    Marker Score: 854
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.98
    Marker Score: 1,053
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,390
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.97
    Marker Score: 248
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.96
    Marker Score: 349
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.96
    Marker Score: 1,160
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.96
    Marker Score: 1,360
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.95
    Marker Score: 627
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.95
    Marker Score: 322
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,399
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 482
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.93
    Marker Score: 3,322
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 0.93
    Marker Score: 767
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.93
    Marker Score: 349
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.93
    Marker Score: 502
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.93
    Marker Score: 5,953
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 436
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.91
    Marker Score: 1,482
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,708
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.89
    Marker Score: 585
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.89
    Marker Score: 534
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.88
    Marker Score: 428
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 0.88
    Marker Score: 4,728
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.88
    Marker Score: 282
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,294
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.86
    Marker Score: 1,242
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.86
    Marker Score: 3,588
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 308
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.85
    Marker Score: 422
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.85
    Marker Score: 3,678
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.85
    Marker Score: 4,851
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.85
    Marker Score: 680
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.82
    Marker Score: 4,910
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.82
    Marker Score: 215
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 0.82
    Marker Score: 1,877

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit of the CORVET complex**: VPS8 is a critical subunit of the CORVET complex, a protein complex that regulates endosomal trafficking and protein targeting to vacuoles. 2. **Significant expression in diverse cell types**: VPS8 is expressed in a wide range of cell types, including cardiac myocytes, corneal epithelial cells, and neurons, underscoring its importance in maintaining cellular homeostasis. 3. **Involvement in metal ion binding and protein binding**: VPS8 interacts with metal ions and proteins, highlighting its role in regulating protein-protein interactions and endosomal dynamics. 4. **Regulation of snare complex assembly**: VPS8 is involved in the assembly of the snare complex, a critical component of the CORVET complex, which regulates vesicle fusion and protein targeting. **Pathways and Functions:** 1. **Corvet complex**: VPS8 is a subunit of the CORVET complex, which regulates endosomal trafficking and protein targeting to vacuoles. 2. **Early endosome**: VPS8 plays a role in regulating the early endosome, a critical organelle involved in protein sorting and degradation. 3. **Endosomal vesicle fusion**: VPS8 is involved in the regulation of endosomal vesicle fusion, a process critical for maintaining cellular homeostasis. 4. **Hops complex**: VPS8 interacts with the Hops complex, a protein complex involved in regulating endosomal trafficking and protein targeting. 5. **Late endosome**: VPS8 plays a role in regulating the late endosome, a critical organelle involved in protein sorting and degradation. 6. **Metal ion binding**: VPS8 interacts with metal ions, which are critical for regulating protein-protein interactions and endosomal dynamics. 7. **Protein binding**: VPS8 interacts with proteins, which are critical for regulating protein-protein interactions and endosomal dynamics. 8. **Protein targeting to vacuole**: VPS8 is involved in regulating protein targeting to vacuoles, a critical process involved in protein degradation and cellular homeostasis. 9. **Protein transport**: VPS8 plays a role in regulating protein transport, a critical process involved in maintaining cellular homeostasis. 10. **Regulation of snare complex assembly**: VPS8 is involved in the assembly of the snare complex, a critical component of the CORVET complex, which regulates vesicle fusion and protein targeting. **Clinical Significance:** 1. **Neurological disorders**: VPS8 dysregulation has been implicated in various neurological disorders, including Parkinson's disease and Huntington's disease. 2. **Cancer**: VPS8 dysregulation has been implicated in various types of cancer, including breast cancer and lung cancer. 3. **Cardiac disease**: VPS8 dysregulation has been implicated in various cardiac diseases, including heart failure and cardiac arrhythmias. 4. **Neuromuscular disorders**: VPS8 dysregulation has been implicated in various neuromuscular disorders, including muscular dystrophy and myasthenia gravis. 5. **Endosomal dysfunction**: VPS8 dysregulation has been implicated in endosomal dysfunction, a critical process involved in protein degradation and cellular homeostasis. In conclusion, VPS8 is a critical subunit of the CORVET complex, which plays a pivotal role in regulating protein trafficking and endosomal dynamics. Its involvement in metal ion binding, protein binding, and protein targeting to vacuoles highlights its importance in maintaining cellular homeostasis. Dysregulation of VPS8 has been implicated in various neurological, cancer, cardiac, and neuromuscular disorders, emphasizing the need for further research into its role in human disease.

Genular Protein ID: 756327349

Symbol: VPS8_HUMAN

Name: Vacuolar protein sorting-associated protein 8 homolog

UniProtKB Accession Codes:

Q8N3P4 A8K8Q8 B9EIQ1 C9JB61 O94896 Q63HP2 Q9BVP9 Q9H9B0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 8 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 2 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 3 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9872452

Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9872452

DOI: 10.1093/dnares/5.5.277

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25266290

Title: Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.

PubMed ID: 25266290

DOI: 10.1111/tra.12232

Sequence Information:

  • Length: 1428
  • Mass: 161754
  • Checksum: 97FB5E8D453BBCB6
  • Sequence:
    • MENEPDHENV EQSLCAKTSE EELNKSFNLE ASLSKFSYID MDKELEFKND LIDDKEFDIP 
QVDTPPTLES ILNETDDEDE SFILEDPTLL NIDTIDSHSY DTSSVASSDS GDRTNLKRKK 
KLPDSFSLHG SVMRHSLLKG ISAQIVSAAD KVDAGLPTAI AVSSLIAVGT SHGLALIFGK 
DQNQALRLCL GSTSVGGQYG AISALSINND CSRLLCGFAK GQITMWDLAS GKLLRSITDA 
HPPGTAILHI KFTDDPTLAI CNDSGGSVFE LTFKRVMGVR TCESRCLFSG SKGEVCCIEP 
LHSKPELKDH PITQFSLLAM ASLTKILVIG LKPSLKVWMT FPYGRMDPSS VPLLAWHFVA 
VQNYVNPMLA FCRGDVVHFL LVKRDESGAI HVTKQKHLHL YYDLINFTWI NSRTVVLLDS 
VEKLHVIDRQ TQEELETVEI SEVQLVYNSS HFKSLATGGN VSQALALVGE KACYQSISSY 
GGQIFYLGTK SVYVMMLRSW RERVDHLLKQ DCLTEALALA WSFHEGKAKA VVGLSGDASK 
RKAIVADRMV EILFHYADRA LKKCPDQGKI QVMEQHFQDM VPVIVDYCLL LQRKDLLFSQ 
MYDKLSENSV AKGVFLECLE PYILSDKLVG ITPQVMKDLI VHFQDKKLME NVEALIVHMD 
ITSLDIQQVV LMCWENRLYD AMIYVYNRGM NEFISPMEKL FRVIAPPLNA GKTLTDEQVV 
MGNKLLVYIS CCLAGRAYPL GDIPEDLVPL VKNQVFEFLI RLHSAEASPE EEIYPYIRTL 
LHFDTREFLN VLALTFEDFK NDKQAVEYQQ RIVDILLKVM VENSDFTPSQ VGCLFTFLAR 
QLAKPDNTLF VNRTLFDQVL EFLCSPDDDS RHSERQQVLL ELLQAGGIVQ FEESRLIRMA 
EKAEFYQICE FMYEREHQYD KIIDCYLRDP LREEEVFNYI HNILSIPGHS AEEKQSVWQK 
AMDHIEELVS LKPCKAAELV ATHFSGHIET VIKKLQNQVL LFKFLRSLLD PREGIHVNQE 
LLQISPCITE QFIELLCQFN PTQVIETLQV LECYRLEETI QITQKYQLHE VTAYLLEKKG 
DIHGAFLIML ERLQSKLQEV THQGENTKED PSLKDVEDTM VETIALCQRN SHNLNQQQRE 
ALWFPLLEAM MAPQKLSSSA IPHLHSEALK SLTMQVLNSM AAFIALPSIL QRILQDPVYG 
KGKLGEIQGL ILGMLDTFNY EQTLLETTTS LLNQDLHWSL CNLRASVTRG LNPKQDYCSI 
CLQQYKRRQE MADEIIVFSC GHLYHSFCLQ NKECTVEFEG QTRWTCYKCS SSNKVGKLSE 
NSSEIKKGRI TPSQVKMSPS YHQSKGDPTA KKGTSEPVLD PQQIQAFDQL CRLYRGSSRL 
ALLTELSQNR SSESYRPFSG SQSAPAFNSI FQNENFQLQL IPPPVTED

Genular Protein ID: 1832257410

Symbol: B3KPR6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KPR6

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SUPFAM 2

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 1196
  • Mass: 135525
  • Checksum: A3EB023D29315C62
  • Sequence:
    • MENEPDHENV EQSLCAKTSE EELNKSFNLE ASLSKFSYID MDKELEFKND LIDDKEFDIP 
QVDTPPTLES ILNETDDEDE SFVLEDPTLL NIDTIDSHSY DTSSVASSDS GDRTNLKRKK 
KLPDSFSLHG SVMRHSLLKG ISAQIVSAAD KVDAGLPTAI AVSSLIAVGT SHGLALIFGK 
DQNQALRLCL GSTSVGGQYG AISALSINND CSRLLCGFAK GQITMWDLAS GKLLRSITDA 
HPPGTAILHI KFTDDPTLAI CNDSGGSVFE LTFKRVMGVR TCESRCLFSG SKGEVCCIEP 
LHSKPELKDH PITQFSLLAM ASLTKILVIG LKPSLKVWMT FPYGRMDPSS VPLLAWHFVA 
VQNYVNPMLA FCRGDVVHFL LVKRDESGAI HVTKQKHLHL YYDLINFTWI NSRTVVLLDS 
VEKLHVIDRQ TQEELETVEI SEVQLVYNSS HFKSLATGGN VSQALALVGE KACYQSISSY 
GGQIFYLGTK SVYVMMLRSW RERVDHLLKQ DCLTEALALA WSFHEGKAKA VVGLSGDASK 
RKAIVADRMV EILFHYADRA LKKCPDQGKI QVMEQHFQDM VPVIVDYCLL LQRKDLLFSQ 
MYDKLSENSV AKGVFLECLE PYILSDKLVG ITPQVMKDLI VHFQDKKLME NVEALIVHMD 
ITSLDIQQVV LMCWENRLYD AMIYVYNRGM NEFISPMEKL FRVIAPPLNA GKTLTDEQVV 
MGNKLLVYIS CCLAGRAYPL GDIPEDLVPL VKNQVFEFLI RLHSAEASPE EEIYPYIRTL 
LHFDTREFLN VLALTFEDFK NDKQAVEYQQ RIVDILLKVM VENSDFTPSQ VGCLFTFLAR 
QLAKPDNTLF VNRTLFDQVL EFLCSPDDDS RHSERQQVLL ELLQAGGIVQ FEESRLIRMA 
EKAEFYQICE FMYEREHQYD KIIDCYLRDP LREEEVFNYI HNILSIPGHS AEEKQSVWQK 
AMDHIEELVS LKPCKAAELV ATHFSGHIET VIKKLQNQVL LFKFLRSLLD PREGIHVNQE 
LLQISPCITE QFIELLCQFN PTQVIETLQV LECYRLEETI QITQKYQLHE VTAYLLEKKG 
DIHGAFLIML ERLQSKLQEV THQGENTKED PSLKDVEDTM VETIALCQRN SHNLNQQQRE 
ALWFPLLEAM MAPQKLSSSA IPHLHSEALK SLTMQVLNSM AAFIALSNNK CSVFKF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.