Details for: FNBP4
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.83
Marker Score: 63,256 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.73
Marker Score: 11,415 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.61
Marker Score: 3,517 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.51
Marker Score: 1,463 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.49
Marker Score: 3,011 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.43
Marker Score: 82,650 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.42
Marker Score: 5,315 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.38
Marker Score: 2,962 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 2.3
Marker Score: 8,194 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 2.26
Marker Score: 2,225 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.19
Marker Score: 38,814 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.12
Marker Score: 4,085 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.09
Marker Score: 611 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 2.05
Marker Score: 995 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.04
Marker Score: 2,316 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 2.04
Marker Score: 1,920 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.02
Marker Score: 2,127 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.01
Marker Score: 40,034 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 1.99
Marker Score: 4,862 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.98
Marker Score: 29,616 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.98
Marker Score: 73,000 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.98
Marker Score: 627 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.97
Marker Score: 74,800 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.96
Marker Score: 5,493 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.95
Marker Score: 819 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 1.95
Marker Score: 2,693 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 1.95
Marker Score: 1,172 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.94
Marker Score: 41,312 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 1.93
Marker Score: 102,287 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.93
Marker Score: 611 - Cell Name: follicular B cell (CL0000843)
Fold Change: 1.93
Marker Score: 2,094 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.93
Marker Score: 2,127 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 1.91
Marker Score: 676 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.91
Marker Score: 1,693 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.91
Marker Score: 2,196 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.9
Marker Score: 7,862 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.89
Marker Score: 14,514 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.88
Marker Score: 1,239 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.88
Marker Score: 2,773 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.87
Marker Score: 2,018 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 1.86
Marker Score: 3,891 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.85
Marker Score: 18,741 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.84
Marker Score: 1,453 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.84
Marker Score: 17,287 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 1.84
Marker Score: 7,877 - Cell Name: fat cell (CL0000136)
Fold Change: 1.8
Marker Score: 1,008 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.8
Marker Score: 110,899 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.79
Marker Score: 428 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.79
Marker Score: 3,768 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.78
Marker Score: 723 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.78
Marker Score: 28,524 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.77
Marker Score: 6,855 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.77
Marker Score: 1,036 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.77
Marker Score: 762 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 1.76
Marker Score: 1,549 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.76
Marker Score: 1,220 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.74
Marker Score: 969 - Cell Name: unswitched memory B cell (CL0000970)
Fold Change: 1.74
Marker Score: 1,017 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.74
Marker Score: 1,499 - Cell Name: podocyte (CL0000653)
Fold Change: 1.73
Marker Score: 640 - Cell Name: neuron (CL0000540)
Fold Change: 1.73
Marker Score: 7,026 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.72
Marker Score: 1,494 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 1.72
Marker Score: 1,302 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 1.72
Marker Score: 1,609 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 1.72
Marker Score: 5,419 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.7
Marker Score: 19,187 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.7
Marker Score: 7,078 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.69
Marker Score: 7,815 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.69
Marker Score: 16,038 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 1.69
Marker Score: 2,482 - Cell Name: Unknown (CL0000548)
Fold Change: 1.69
Marker Score: 1,228 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.68
Marker Score: 837 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 1.67
Marker Score: 1,364 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.66
Marker Score: 1,527 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.66
Marker Score: 477 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.65
Marker Score: 1,031 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.65
Marker Score: 14,166 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 1.65
Marker Score: 1,293 - Cell Name: pro-B cell (CL0000826)
Fold Change: 1.65
Marker Score: 1,590 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 1.65
Marker Score: 812 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.64
Marker Score: 1,654 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 1.64
Marker Score: 1,119 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 1.63
Marker Score: 1,181 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.62
Marker Score: 552 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.62
Marker Score: 972 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 1.61
Marker Score: 2,884 - Cell Name: memory B cell (CL0000787)
Fold Change: 1.61
Marker Score: 1,221 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.61
Marker Score: 603 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.61
Marker Score: 16,596 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 1.61
Marker Score: 473 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.61
Marker Score: 7,894 - Cell Name: neural cell (CL0002319)
Fold Change: 1.6
Marker Score: 774 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 1.6
Marker Score: 1,172 - Cell Name: Schwann cell (CL0002573)
Fold Change: 1.6
Marker Score: 555 - Cell Name: basal cell (CL0000646)
Fold Change: 1.6
Marker Score: 2,064 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.6
Marker Score: 350 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 1.6
Marker Score: 1,345 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 1.59
Marker Score: 2,772 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.59
Marker Score: 554 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.59
Marker Score: 3,973
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 737974157
Symbol: FNBP4_HUMAN
Name: Formin-binding protein 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 10748127
Title: Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains.
PubMed ID: 10748127
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23703728
Title: Whole-exome sequencing identified a homozygous FNBP4 mutation in a family with a condition similar to microphthalmia with limb anomalies.
PubMed ID: 23703728
DOI: 10.1002/ajmg.a.35983
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 1017
- Mass: 110266
- Checksum: 510DC8011B5973AD
- Sequence:
MGKKSRAVPG RRPILQLSPP GPRGSTPGRD PEPEPDTEPD STAAVPSQPA PSAATTTTTA VTAAAASDDS PSEDEQEAVQ EVPRVVQNPP KPVMTTRPTA VKATGGLCLL GAYADSDDDD NDVSEKLAQS KETNGNQSTD IDSTLANFLA EIDAITAPQP AAPVGASAPP PTPPRPEPKE AATSTLSSST SNGTDSTQTS GWQYDTQCSL AGVGIEMGDW QEVWDENTGC YYYWNTQTNE VTWELPQYLA TQVQGLQHYQ PSSVPGAETS FVVNTDIYSK EKTISVSSSK SGPVIAKREV KKEVNEGIQA LSNSEEEKKG VAASLLAPLL PEGIKEEEER WRRKVICKEE PVSEVKETST TVEEATTIVK PQEIMLDNIE DPSQEDLCSV VQSGESEEEE EQDTLELELV LERKKAELRA LEEGDGSVSG SSPRSDISQP ASQDGMRRLM SKRGKWKMFV RATSPESTSR SSSKTGRDTP ENGETAIGAE NSEKIDENSD KEMEVEESPE KIKVQTTPKV EEEQDLKFQI GELANTLTSK FEFLGINRQS ISNFHVLLLQ TETRIADWRE GALNGNYLKR KLQDAAEQLK QYEINATPKG WSCHWDRDHR RYFYVNEQSG ESQWEFPDGE EEEEESQAQE NRDETLAKQT LKDKTGTDSN STESSETSTG SLCKESFSGQ VSSSSLMPLT PFWTLLQSNV PVLQPPLPLE MPPPPPPPPE SPPPPPPPPP PAEDGEIQEV EMEDEGSEEP PAPGTEEDTP LKPSAQTTVV TSQSSVDSTI SSSSSTKGIK RKATEISTAV VQRSATIGSS PVLYSQSAIA TGHQAAGIGN QATGIGHQTI PVSLPAAGMG HQARGMSLQS NYLGLAAAPA IMSYAECSVP IGVTAPSLQP VQARGAVPTA TIIEPPPPPP PPPPPPPPAP KMPPPEKTKK GRKDKAKKSK TKMPSLVKKW QSIQRELDEE DNSSSSEEDR ESTAQKRIEE WKQQQLVSGM AERNANFEAL PEDWRARLKR RKMAPNT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.