Details for: OBSL1

Gene ID: 23363

Symbol: OBSL1

Ensembl ID: ENSG00000124006

Description: obscurin like cytoskeletal adaptor 1

Associated with

Other Information

Genular Protein ID: 3651927063

Symbol: OBSL1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17289344

Title: Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin.

PubMed ID: 17289344

DOI: 10.1016/j.ygeno.2006.12.004

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19481195

Title: The primordial growth disorder 3-M syndrome connects ubiquitination to the cytoskeletal adaptor OBSL1.

PubMed ID: 19481195

DOI: 10.1016/j.ajhg.2009.04.021

PubMed ID: 21737058

Title: Exome sequencing identifies CCDC8 mutations in 3-M syndrome, Suggesting that CCDC8 Contributes in a Pathway with CUL7 and OBSL1 to Control Human Growth.

PubMed ID: 21737058

DOI: 10.1016/j.ajhg.2011.05.028

PubMed ID: 21572988

Title: An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.

PubMed ID: 21572988

DOI: 10.1371/journal.pbio.1001060

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24793695

Title: The 3M complex maintains microtubule and genome integrity.

PubMed ID: 24793695

DOI: 10.1016/j.molcel.2014.03.047

PubMed ID: 24793696

Title: CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.

PubMed ID: 24793696

DOI: 10.1016/j.molcel.2014.03.046

PubMed ID: 23018678

Title: Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.

PubMed ID: 23018678

DOI: 10.1530/jme-12-0034

PubMed ID: 20489725

Title: Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.

PubMed ID: 20489725

DOI: 10.1038/embor.2010.65

PubMed ID: 20133654

Title: Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

PubMed ID: 20133654

DOI: 10.1073/pnas.0913736107

Sequence Information:

  • Length: 1896
  • Mass: 206947
  • Checksum: 6D592AC3E30E9ACA
  • Sequence:
  • MKASSGDQGS PPCFLRFPRP VRVVSGAEAE LKCVVLGEPP PVVVWEKGGQ QLAASERLSF 
    PADGAEHGLL LTAALPTDAG VYVCRARNAA GEAYAAAAVT VLEPPASDPE LQPAERPLPS 
    PGSGEGAPVF LTGPRSQWVL RGAEVVLTCR AGGLPEPTLY WEKDGMALDE VWDSSHFALQ 
    PGRAEDGPGA SLALRILAAR LPDSGVYVCH ARNAHGHAQA GALLQVHQPP ESPPADPDEA 
    PAPVVEPLKC APKTFWVNEG KHAKFRCYVM GKPEPEIEWH WEGRPLLPDR RRLMYRDRDG 
    GFVLKVLYCQ AKDRGLYVCA ARNSAGQTLS AVQLHVKEPR LRFTRPLQDV EGREHGIAVL 
    ECKVPNSRIP TAWFREDQRL LPCRKYEQIE EGTVRRLIIH RLKADDDGIY LCEMRGRVRT 
    VANVTVKGPI LKRLPRKLDV LEGENAVLLV ETLEAGVEGR WSRDGEELPV ICQSSSGHMH 
    ALVLPGVTRE DAGEVTFSLG NSRTTTLLRV KCVKHSPPGP PILAEMFKGH KNTVLLTWKP 
    PEPAPETPFI YRLERQEVGS EDWIQCFSIE KAGAVEVPGD CVPSEGDYRF RICTVSGHGR 
    SPHVVFHGSA HLVPTARLVA GLEDVQVYDG EDAVFSLDLS TIIQGTWFLN GEELKSNEPE 
    GQVEPGALRY RIEQKGLQHR LILHAVKHQD SGALVGFSCP GVQDSAALTI QESPVHILSP 
    QDRVSLTFTT SERVVLTCEL SRVDFPATWY KDGQKVEESE LLVVKMDGRK HRLILPEAKV 
    QDSGEFECRT EGVSAFFGVT VQDPPVHIVD PREHVFVHAI TSECVMLACE VDREDAPVRW 
    YKDGQEVEES DFVVLENEGP HRRLVLPATQ PSDGGEFQCV AGDECAYFTV TITDVSSWIV 
    YPSGKVYVAA VRLERVVLTC ELCRPWAEVR WTKDGEEVVE SPALLLQKED TVRRLVLPAV 
    QLEDSGEYLC EIDDESASFT VTVTEPPVRI IYPRDEVTLI AVTLECVVLM CELSREDAPV 
    RWYKDGLEVE ESEALVLERD GPRCRLVLPA AQPEDGGEFV CDAGDDSAFF TVTVTAPPER 
    IVHPAARSLD LHFGAPGRVE LRCEVAPAGS QVRWYKDGLE VEASDALQLG AEGPTRTLTL 
    PHAQPEDAGE YVCETRHEAI TFNVILAEPP VQFLALETTP SPLCVAPGEP VVLSCELSRA 
    GAPVVWSHNG RPVQEGEGLE LHAEGPRRVL CIQAAGPAHA GLYTCQSGAA PGAPSLSFTV 
    QVAEPPVRVV APEAAQTRVR STPGGDLELV VHLSGPGGPV RWYKDGERLA SQGRVQLEQA 
    GARQVLRVQG ARSGDAGEYL CDAPQDSRIF LVSVEEPLLV KLVSELTPLT VHEGDDATFR 
    CEVSPPDADV TWLRNGAVVT PGPQVEMAQN GSSRILTLRG CQLGDAGTVT LRAGSTATSA 
    RLHVRETELL FLRRLQDVRA EEGQDVCLEV ETGRVGAAGA VRWVRGGQPL PHDSRLSMAQ 
    DGHIHRLFIH GVILADQGTY GCESHHDRTL ARLSVRPRQL RVLRPLEDVT ISEGGSATFQ 
    LELSQEGVTG EWARGGVQLY PGPKCHIHSD GHRHRLVLNG LGLADSGCVS FTADSLRCAA 
    RLIVREVPVT IVRGPHDLEV TEGDTATFEC ELSQALADVT WEKDGNALTP SPRLRLQALG 
    TRRLLQLRRC GPSDAGTYSC AVGTARAGPV RLTVRERTVA VLSELRSVSA REGDGATFEC 
    TVSEVETTGR WELGGRPLRP GARVRIRQEG KKHILVLSEL RAEDAGEVRF QAGPAQSLAL 
    LEVEALPLQM CRHPPREKTV LVGRRAVLEV TVSRSGGHVC WLREGAELCP GDKYEMRSHG 
    PTHSLVIHDV RPEDQGTYCC QAGQDSTHTR LLVEGN

Genular Protein ID: 3632765343

Symbol: Q9H8B3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 442
  • Mass: 47378
  • Checksum: DEC475AE8B964195
  • Sequence:
  • MCELSREDAP VRWYKDGLEV EESEALVLER DGPRCRLVLP AAQPEDGGEF VCDAGDDSAF 
    FTVTVTAPPE RIVHPAARSL DLHFGAPGRV ELRCEVAPAG SQVRWYKDGL EVEASDALQL 
    GAEGPTRTLT LPHAQPEDAG EYVCETRHEA ITFNVILAEP PVQFLALETT PSPLCVAPGE 
    PVVLSCELSR AGAPVVWSHN GGPVQEGEGL ELHAEGPRRV LCIQAAGPAH AGLYTCQSGA 
    APGAPSLSFT VQVAEPLLVK LVSDLTPLTV HEGDDATFRC EVSPPDADVT WLRNGAVVTP 
    GPQVEMAQNG SSRILTLRGC QLGDAGTVTL RAGSTATSAR LHVRETELLF LRRLQDVRAE 
    EGQDVCLEME TGRVGAAGAV RWVRGGQPLP HDSRLSMAQD GHIHRLFIHG VILADQGTYG 
    CESHHDRTLA RLSVRRECPV LS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.