Details for: ARHGEF12
Associated with
Other Information
Genular Protein ID: 2402678750
Symbol: ARHGC_HUMAN
Name: Rho guanine nucleotide exchange factor 12
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10681437
Title: Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia.
PubMed ID: 10681437
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9205841
Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9205841
PubMed ID: 11094164
Title: Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho.
PubMed ID: 11094164
PubMed ID: 11724822
Title: Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF.
PubMed ID: 11724822
PubMed ID: 12372594
Title: B plexins activate Rho through PDZ-RhoGEF.
PubMed ID: 12372594
PubMed ID: 12183458
Title: Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.
PubMed ID: 12183458
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20844236
Title: HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway.
PubMed ID: 20844236
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 15331592
Title: Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
PubMed ID: 15331592
PubMed ID: 18411422
Title: Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor.
PubMed ID: 18411422
DOI: 10.1110/ps.073416508
Sequence Information:
- Length: 1544
- Mass: 173232
- Checksum: 0B7E319CF7C7A224
- Sequence:
MSGTQSTITD RFPLKKPIRH GSILNRESPT DKKQKVERIA SHDFDPTDSS SKKTKSSSEE SRSEIYGLVQ RCVIIQKDDN GFGLTVSGDN PVFVQSVKED GAAMRAGVQT GDRIIKVNGT LVTHSNHLEV VKLIKSGSYV ALTVQGRPPG SPQIPLADSE VEPSVIGHMS PIMTSPHSPG ASGNMERITS PVLMGEENNV VHNQKVEILR KMLQKEQERL QLLQEDYNRT PAQRLLKEIQ EAKKHIPQLQ EQLSKATGSA QDGAVVTPSR PLGDTLTVSE AETDPGDVLG RTDCSSGDAS RPSSDNADSP KSGPKERIYL EENPEKSETI QDTDTQSLVG SPSTRIAPHI IGAEDDDFGT EHEQINGQCS CFQSIELLKS RPAHLAVFLH HVVSQFDPAT LLCYLYSDLY KHTNSKETRR IFLEFHQFFL DRSAHLKVSV PDEMSADLEK RRPELIPEDL HRHYIQTMQE RVHPEVQRHL EDFRQKRSMG LTLAESELTK LDAERDKDRL TLEKERTCAE QIVAKIEEVL MTAQAVEEDK SSTMQYVILM YMKHLGVKVK EPRNLEHKRG RIGFLPKIKQ SMKKDKEGEE KGKRRGFPSI LGPPRRPSRH DNSAIGRAME LQKARHPKHL STPSSVSPEP QDSAKLRQSG LANEGTDAGY LPANSMSSVA SGASFSQEGG KENDTGSKQV GETSAPGDTL DGTPRTLNTV FDFPPPPLDQ VQEEECEVER VTEHGTPKPF RKFDSVAFGE SQSEDEQFEN DLETDPPNWQ QLVSREVLLG LKPCEIKRQE VINELFYTER AHVRTLKVLD QVFYQRVSRE GILSPSELRK IFSNLEDILQ LHIGLNEQMK AVRKRNETSV IDQIGEDLLT WFSGPGEEKL KHAAATFCSN QPFALEMIKS RQKKDSRFQT FVQDAESNPL CRRLQLKDII PTQMQRLTKY PLLLDNIAKY TEWPTEREKV KKAADHCRQI LNYVNQAVKE AENKQRLEDY QRRLDTSSLK LSEYPNVEEL RNLDLTKRKM IHEGPLVWKV NRDKTIDLYT LLLEDILVLL QKQDDRLVLR CHSKILASTA DSKHTFSPVI KLSTVLVRQV ATDNKALFVI SMSDNGAQIY ELVAQTVSEK TVWQDLICRM AASVKEQSTK PIPLPQSTPG EGDNDEEDPS KLKEEQHGIS VTGLQSPDRD LGLESTLISS KPQSHSLSTS GKSEVRDLFV AERQFAKEQH TDGTLKEVGE DYQIAIPDSH LPVSEERWAL DALRNLGLLK QLLVQQLGLT EKSVQEDWQH FPRYRTASQG PQTDSVIQNS ENIKAYHSGE GHMPFRTGTG DIATCYSPRT STESFAPRDS VGLAPQDSQA SNILVMDHMI MTPEMPTMEP EGGLDDSGEH FFDAREAHSD ENPSEGDGAV NKEEKDVNLR ISGNYLILDG YDPVQESSTD EEVASSLTLQ PMTGIPAVES THQQQHSPQN THSDGAISPF TPEFLVQQRW GAMEYSCFEI QSPSSCADSQ SQIMEYIHKI EADLEHLKKV EESYTILCQR LAGSALTDKH SDKS
Genular Protein ID: 206032439
Symbol: B4E2K6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1278
- Mass: 143947
- Checksum: A6279845201B370A
- Sequence:
MSGTQSTITD RFPLKKPIRH GSILNRESPT DKKQKVERIA SHDFDPTGLV QRCVIIQKDD NGFGLTVSGD NPVFVQSVKE DGAAMRAGVQ TGDRIIKVNG TLVTHSNHLE VVKLIKSGSY VALTVQGRPP GSPQIPLADS EVEPSVIGHM SPIMTSPHSP GASGNMERIT SPVLMGEENN VVHNQKVEIL RKMLQKEQER LQLLQEDYNR TPAQRLLKEI QEAKKHIPQL QEQLSKATGS AQDGAVVTPS RPLGDTLTVS EAETDPGDVL GRTDCSSGDA SRPSSDNADS PKSGPKERIY LEENPEKSET IQDTDTQSLV GSPSTRIAPH IIGAEDDDFG TEHEQINGQC SCFQSIELLK SRPAHLAVFL HHVVSQFDPA TLLCYLYSDL YKHTNSKETR RIFLEFHQFF LDRSAHLKVS VPDEMSADLE KRRPELIPED LHRHYIQTMQ ERVHPEVQRH LEDFRQKRSM GLTLAESELT KLDAERDKDR LTLEKERTCA EQIVAKIEEV LMTAQAVEED KSSTMQYVIL MYMKHLGVKV KEPRNLEHKR GRIGFLPKIK QSMKKDKEGE EKGKRRGFPS ILGPPRRPSR HDNSAIGRAM ELQKARHPKH LSTPSSVSPE PQDSAKLRQS GLANEGTDAG YLPANSMSSV ASGASFSQEG GKENDTGSKQ VGETSAPGDT LDGTPRTLNT VFDFPPPPLD QVQEEECEVE RVTEHGTPKP FRKFDSVAFG ESQSEDEQFE NDLETDPPNW QQLVSREVLL GLKPCEIKRQ EVINELFYTE RAHVRTLKVL DQVFYQRVSR EGILSPSELR KIFSNLEDIL QLHIGLNEQM KAVRKRNETS VIDQIGEDLL TWFSGPGEEK LKHAAATFCS NQPFALEMIK SRQKKDSRFQ TFVQDAESNP LCRRLQLKDI IPTQMQRLTK YPLLLDNIAK YTEWPTEREK VKKAADHCRQ ILNYVNQAVK EAENKQRLED YQRRLDTSSL KLSEYPNVEE LRNLDLTKRK MIHEGPLVWK VNRDKTIDLY TLLLEDILVL LQKQDDRLVL RCHSKILAST ADSKHTFSPV IKLSTVLVRQ VATDNKALFV ISMSDNGAQI YELVAQTVSE KTVWQDLICR MAASVKEQST KPIPLPQSTP GEGDNDEEDP SKLKEEQHGI SVTGLQSPDR DLGLESTLIS SKPQSHSLST SGKSEVRDLF VAERQFAKEQ HTDGTLKEVG EDYQIAIPDS HLPVSEERWA LDALRNLGLL KQLLVQQLGL TEKSVQEDWQ HFPRYRTASQ GPQTDSVI
Genular Protein ID: 1276948125
Symbol: E9PMR6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1441
- Mass: 161909
- Checksum: 7343555DCD901EDD
- Sequence:
MRAGVQTGDR IIKVNGTLVT HSNHLEVVKL IKSGSYVALT VQGRPPGSPQ IPLADSEVEP SVIGHMSPIM TSPHSPGASG NMERITSPVL MGEENNVVHN QKVEILRKML QKEQERLQLL QEDYNRTPAQ RLLKEIQEAK KHIPQLQEQL SKATGSAQDG AVVTPSRPLG DTLTVSEAET DPGDVLGRTD CSSGDASRPS SDNADSPKSG PKERIYLEEN PEKSETIQDT DTQSLVGSPS TRIAPHIIGA EDDDFGTEHE QINGQCSCFQ SIELLKSRPA HLAVFLHHVV SQFDPATLLC YLYSDLYKHT NSKETRRIFL EFHQFFLDRS AHLKVSVPDE MSADLEKRRP ELIPEDLHRH YIQTMQERVH PEVQRHLEDF RQKRSMGLTL AESELTKLDA ERDKDRLTLE KERTCAEQIV AKIEEVLMTA QAVEEDKSST MQYVILMYMK HLGVKVKEPR NLEHKRGRIG FLPKIKQSMK KDKEGEEKGK RRGFPSILGP PRRPSRHDNS AIGRAMELQK ARHPKHLSTP SSVSPEPQDS AKLRQSGLAN EGTDAGYLPA NSMSSVASGA SFSQEGGKEN DTGSKQVGET SAPGDTLDGT PRTLNTVFDF PPPPLDQVQE EECEVERVTE HGTPKPFRKF DSVAFGESQS EDEQFENDLE TDPPNWQQLV SREVLLGLKP CEIKRQEVIN ELFYTERAHV RTLKVLDQVF YQRVSREGIL SPSELRKIFS NLEDILQLHI GLNEQMKAVR KRNETSVIDQ IGEDLLTWFS GPGEEKLKHA AATFCSNQPF ALEMIKSRQK KDSRFQTFVQ DAESNPLCRR LQLKDIIPTQ MQRLTKYPLL LDNIAKYTEW PTEREKVKKA ADHCRQILNY VNQAVKEAEN KQRLEDYQRR LDTSSLKLSE YPNVEELRNL DLTKRKMIHE GPLVWKVNRD KTIDLYTLLL EDILVLLQKQ DDRLVLRCHS KILASTADSK HTFSPVIKLS TVLVRQVATD NKALFVISMS DNGAQIYELV AQTVSEKTVW QDLICRMAAS VKEQSTKPIP LPQSTPGEGD NDEEDPSKLK EEQHGISVTG LQSPDRDLGL ESTLISSKPQ SHSLSTSGKS EVRDLFVAER QFAKEQHTDG TLKEVGEDYQ IAIPDSHLPV SEERWALDAL RNLGLLKQLL VQQLGLTEKS VQEDWQHFPR YRTASQGPQT DSVIQNSENI KAYHSGEGHM PFRTGTGDIA TCYSPRTSTE SFAPRDSVGL APQDSQASNI LVMDHMIMTP EMPTMEPEGG LDDSGEHFFD AREAHSDENP SEGDGAVNKE EKDVNLRISG NYLILDGYDP VQESSTDEEV ASSLTLQPMT GIPAVESTHQ QQHSPQNTHS DGAISPFTPE FLVQQRWGAM EYSCFEIQSP SSCADSQSQI MEYIHKIEAD LEHLKKVEES YTILCQRLAG SALTDKHSDK S
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.