Details for: LARP1
Associated with
Other Information
Genular Protein ID: 2314603289
Symbol: LARP1_HUMAN
Name: La-related protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 9872452
Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9872452
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17924679
Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
PubMed ID: 17924679
DOI: 10.1021/pr070152u
PubMed ID: 17693683
Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
PubMed ID: 17693683
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20430826
Title: The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration.
PubMed ID: 20430826
DOI: 10.1093/nar/gkq294
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23711370
Title: LARP1 specifically recognizes the 3' terminus of poly(A) mRNA.
PubMed ID: 23711370
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24159927
Title: LARP1 predict the prognosis for early-stage and AFP-normal hepatocellular carcinoma.
PubMed ID: 24159927
PubMed ID: 24532714
Title: Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation.
PubMed ID: 24532714
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 26735137
Title: Characterization of RyDEN (C19orf66) as an interferon-stimulated cellular inhibitor against dengue virus replication.
PubMed ID: 26735137
PubMed ID: 25940091
Title: La-related protein 1 (LARP1) represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1).
PubMed ID: 25940091
PubMed ID: 28650797
Title: LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.
PubMed ID: 28650797
DOI: 10.7554/elife.25237
PubMed ID: 28673543
Title: Autogenous Control of 5'TOP mRNA Stability by 40S Ribosomes.
PubMed ID: 28673543
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29244122
Title: La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.
PubMed ID: 29244122
DOI: 10.1093/nar/gkx1237
PubMed ID: 26206669
Title: The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
PubMed ID: 26206669
DOI: 10.1093/nar/gkv748
PubMed ID: 28379136
Title: La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
PubMed ID: 28379136
DOI: 10.7554/elife.24146
Sequence Information:
- Length: 1096
- Mass: 123510
- Checksum: CA3E9D30BBC101B7
- Sequence:
MATQVEPLLP GGATLLQAEE HGGLVRKKPP PAPEGKGEPG PNDVRGGEPD GSARRPRPPC AKPHKEGTGQ QERESPRPLQ LPGAEGPAIS DGEEGGGEPG AGGGAAGAAG AGRRDFVEAP PPKVNPWTKN ALPPVLTTVN GQSPPEHSAP AKVVRAAVPK QRKGSKVGDF GDAINWPTPG EIAHKSVQPQ SHKPQPTRKL PPKKDMKEQE KGEGSDSKES PKTKSDESGE EKNGDEDCQR GGQKKKGNKH KWVPLQIDMK PEVPREKLAS RPTRPPEPRH IPANRGEIKG SESATYVPVA PPTPAWQPEI KPEPAWHDQD ETSSVKSDGA GGARASFRGR GRGRGRGRGR GRGGTRTHFD YQFGYRKFDG VEGPRTPKYM NNITYYFDNV SSTELYSVDQ ELLKDYIKRQ IEYYFSVDNL ERDFFLRRKM DADGFLPITL IASFHRVQAL TTDISLIFAA LKDSKVVEIV DEKVRRREEP EKWPLPPIVD YSQTDFSQLL NCPEFVPRQH YQKETESAPG SPRAVTPVPT KTEEVSNLKT LPKGLSASLP DLDSENWIEV KKRPRPSPAR PKKSEESRFS HLTSLPQQLP SQQLMSKDQD EQEELDFLFD EEMEQMDGRK NTFTAWSDEE SDYEIDDRDV NKILIVTQTP HYMRRHPGGD RTGNHTSRAK MSAELAKVIN DGLFYYEQDL WAEKFEPEYS QIKQEVENFK KVNMISREQF DTLTPEPPVD PNQEVPPGPP RFQQVPTDAL ANKLFGAPEP STIARSLPTT VPESPNYRNT RTPRTPRTPQ LKDSSQTSRF YPVVKEGRTL DAKMPRKRKT RHSSNPPLES HVGWVMDSRE HRPRTASISS SPSEGTPTVG SYGCTPQSLP KFQHPSHELL KENGFTQHVY HKYRRRCLNE RKRLGIGQSQ EMNTLFRFWS FFLRDHFNKK MYEEFKQLAL EDAKEGYRYG LECLFRYYSY GLEKKFRLDI FKDFQEETVK DYEAGQLYGL EKFWAFLKYS KAKNLDIDPK LQEYLGKFRR LEDFRVDPPM GEEGNHKRHS VVAGGGGGEG RKRCPSQSSS RPAAMISQPP TPPTGQPVRE DAKWTSQHSN TQTLGK
Genular Protein ID: 1508033540
Symbol: A0A8I5KWU3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
Sequence Information:
- Length: 891
- Mass: 102435
- Checksum: CA141EBBBF30060F
- Sequence:
MKEQEKGEGS DSKESPKTKS DESGEEKNGD EDCQRGGQKK KGNKHKWVPL QIDMKPEVPR EKLASRPTRP PEPRHIPANR GEIKGSESAT YVPVAPPTPA WQPEIKPEPA WHDQDETSSV KSDGAGGARA SFRGRGRGRG RGRGRGRGGT RTHFDYQFGY RKFDGVEGPR TPKYMNNITY YFDNVSSTEL YSVDQELLKD YIKRQIEYYF SVDNLERDFF LRRKMDADGF LPITLIASFH RVQALTTDIS LIFAALKDSK VVEIVDEKVR RREEPEKWPL PPIVDYSQTD FSQLLNCPEF VPRQHYQKET ESAPGSPRAV TPVPTKTEEV SNLKTLPKGL SASLPDLDSE NWIEVKKRPR PSPARPKKSE ESRFSHLTSL PQQLPSQQLM SKDQDEQEEL DFLFDEEMEQ MDGRKNTFTA WSDEESDYEI DDRDVNKILI VTQTPHYMRR HPGGDRTGNH TSRAKMSAEL AKVINDGLFY YEQDLWAEKF EPEYSQIKQE VENFKKVNMI SREQFDTLTP EPPVDPNQEV PPGPPRFQQV PTDALANKLF GAPEPSTIAR SLPTTVPESP NYRNTRTPRT PRTPQLKDSS QTSRFYPVVK EGRTLDAKMP RKRKTRHSSN PPLESHVGWV MDSREHRPRT ASISSSPSEG TPTVGSYGCT PQSLPKFQHP SHELLKENGF TQHVYHKYRR RCLNERKRLG IGQSQEMNTL FRFWSFFLRD HFNKKMYEEF KQLALEDAKE GYRYGLECLF RYYSYGLEKK FRLDIFKDFQ EETVKDYEAG QLYGLEKFWA FLKYSKAKNL DIDPKLQEYL GKFRRLEDFR VDPPMGEEGN HKRHSVVAGG GGGEGRKRCP SQSSSRPAAM ISQPPTPPTG QPVREDAKWT SQHSNTQTLG K
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.