Details for: PUM2

Gene ID: 23369

Symbol: PUM2

Ensembl ID: ENSG00000055917

Description: pumilio RNA binding family member 2

Associated with

Other Information

Genular Protein ID: 76696549

Symbol: PUM2_HUMAN

Name: Pumilio homolog 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12459267

Title: Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.

PubMed ID: 12459267

DOI: 10.1016/s0378-1119(02)01060-0

PubMed ID: 9039502

Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PubMed ID: 9039502

DOI: 10.1093/dnares/3.5.321

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12511597

Title: Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.

PubMed ID: 12511597

DOI: 10.1073/pnas.0234478100

PubMed ID: 12771951

Title: Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.

PubMed ID: 12771951

DOI: 10.1038/sj.onc.1206537

PubMed ID: 12690449

Title: Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells.

PubMed ID: 12690449

DOI: 10.1007/s00427-003-0303-2

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18776931

Title: Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.

PubMed ID: 18776931

DOI: 10.1371/journal.pone.0003164

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19168546

Title: The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.

PubMed ID: 19168546

DOI: 10.1093/molehr/gap004

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21800163

Title: NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.

PubMed ID: 21800163

DOI: 10.1007/s00418-011-0842-y

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22345517

Title: Pumilio facilitates miRNA regulation of the E2F3 oncogene.

PubMed ID: 22345517

DOI: 10.1101/gad.182568.111

PubMed ID: 22955276

Title: Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs.

PubMed ID: 22955276

DOI: 10.1074/jbc.m112.373522

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23125361

Title: The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.

PubMed ID: 23125361

DOI: 10.1093/nar/gks1032

PubMed ID: 25349211

Title: SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1).

PubMed ID: 25349211

DOI: 10.1074/jbc.m114.585505

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25340845

Title: A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.

PubMed ID: 25340845

DOI: 10.1371/journal.ppat.1004417

PubMed ID: 26724866

Title: Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins.

PubMed ID: 26724866

DOI: 10.1016/j.cell.2015.12.017

PubMed ID: 28431233

Title: A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

PubMed ID: 28431233

DOI: 10.1016/j.molcel.2017.03.014

PubMed ID: 21397187

Title: Alternate modes of cognate RNA recognition by human PUMILIO proteins.

PubMed ID: 21397187

DOI: 10.1016/j.str.2010.12.019

Sequence Information:

  • Length: 1066
  • Mass: 114216
  • Checksum: CF6F9D7998CD5D9E
  • Sequence:
  • MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP 
    IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD 
    AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ 
    ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP 
    GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA 
    GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ 
    QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA 
    FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA 
    AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS 
    HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSVGSSASS SATRRESLST SSDLYKRSSS 
    SLAPIGQPFY NSLGFSSSPS PIGMPLPSQT PGHSLTPPPS LSSHGSSSSL HLGGLTNGSG 
    RYISAAPGAE AKYRSASSTS SLFSSSSQLF PPSRLRYNRS DIMPSGRSRL LEDFRNNRFP 
    NLQLRDLIGH IVEFSQDQHG SRFIQQKLER ATPAERQMVF NEILQAAYQL MTDVFGNYVI 
    QKFFEFGSLD QKLALATRIR GHVLPLALQM YGCRVIQKAL ESISSDQQVI SEMVKELDGH 
    VLKCVKDQNG NHVVQKCIEC VQPQSLQFII DAFKGQVFVL STHPYGCRVI QRILEHCTAE 
    QTLPILEELH QHTEQLVQDQ YGNYVIQHVL EHGRPEDKSK IVSEIRGKVL ALSQHKFASN 
    VVEKCVTHAS RAERALLIDE VCCQNDGPHS ALYTMMKDQY ANYVVQKMID MAEPAQRKII 
    MHKIRPHITT LRKYTYGKHI LAKLEKYYLK NSPDLGPIGG PPNGML

Genular Protein ID: 3449825584

Symbol: B7ZL34_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 985
  • Mass: 106003
  • Checksum: AD305125806106C9
  • Sequence:
  • MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP 
    IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD 
    AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ 
    ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP 
    GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA 
    GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ 
    QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA 
    FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA 
    AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS 
    HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSGGLTNGS GRYISAAPGA EAKYRSASST 
    SSLFSSSSQL FPPSRLRYNR SDIMPSGRSR LLEDFRNNRF PNLQLRDLIG HIVEFSQDQH 
    GSRFIQQKLE RATPAERQMV FNEILQAAYQ LMTDVFGNYV IQKFFEFGSL DQKLALATRI 
    RGHVLPLALQ MYGCRVIQKA LESISSDQQS EMVKELDGHV LKCVKDQNGN HVVQKCIECV 
    QPQSLQFIID AFKGQVFVLS THPYGCRVIQ RILEHCTAEQ TLPILEELHQ HTEQLVQDQY 
    GNYVIQHVLE HGRPEDKSKI VSEIRGKVLA LSQHKFASNV VEKCVTHASR AERALLIDEV 
    CCQNDGPHSA LYTMMKDQYA NYVVQKMIDM AEPAQRKIIM HKIRPHITTL RKYTYGKHIL 
    AKLEKYYLKN SPDLGPIGGP PNGML

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.