Details for: PUM2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: photoreceptor cell (CL0000210)
Fold Change: 3.31
Marker Score: 2,490 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 3.01
Marker Score: 2,671 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.99
Marker Score: 12,525 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.93
Marker Score: 2,530 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.9
Marker Score: 12,106 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.9
Marker Score: 51,541 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.85
Marker Score: 6,253 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.8
Marker Score: 1,945 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 2.78
Marker Score: 2,284 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.71
Marker Score: 3,650 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.68
Marker Score: 90,468 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.64
Marker Score: 3,190 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.55
Marker Score: 2,930 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.53
Marker Score: 2,864 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.47
Marker Score: 12,980 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.45
Marker Score: 4,704 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.41
Marker Score: 703 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.39
Marker Score: 5,726 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.39
Marker Score: 2,974 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.38
Marker Score: 1,386 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.34
Marker Score: 10,821 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.32
Marker Score: 88,076 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.3
Marker Score: 1,144 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.28
Marker Score: 45,421 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 2.28
Marker Score: 7,632 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.27
Marker Score: 17,426 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.26
Marker Score: 33,749 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.22
Marker Score: 1,709 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.21
Marker Score: 47,165 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.2
Marker Score: 2,428 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2.19
Marker Score: 2,356 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.15
Marker Score: 683 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.15
Marker Score: 8,915 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.13
Marker Score: 78,415 - Cell Name: stellate neuron (CL0000122)
Fold Change: 2.1
Marker Score: 11,299 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.1
Marker Score: 1,227 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.09
Marker Score: 1,249 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.08
Marker Score: 1,168 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.08
Marker Score: 1,980 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.07
Marker Score: 7,989 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.06
Marker Score: 652 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.05
Marker Score: 45,758 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.98
Marker Score: 1,041 - Cell Name: granule cell (CL0000120)
Fold Change: 1.97
Marker Score: 14,863 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.97
Marker Score: 2,377 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.97
Marker Score: 121,028 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.96
Marker Score: 2,753 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.95
Marker Score: 563 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.94
Marker Score: 18,243 - Cell Name: germ cell (CL0000586)
Fold Change: 1.93
Marker Score: 3,380 - Cell Name: fat cell (CL0000136)
Fold Change: 1.88
Marker Score: 1,049 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.87
Marker Score: 29,997 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.86
Marker Score: 6,109 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.83
Marker Score: 1,016 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.82
Marker Score: 660 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.82
Marker Score: 17,309 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.81
Marker Score: 4,156 - Cell Name: contractile cell (CL0000183)
Fold Change: 1.79
Marker Score: 972 - Cell Name: neuron (CL0000540)
Fold Change: 1.76
Marker Score: 7,184 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.75
Marker Score: 447 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.75
Marker Score: 15,060 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.75
Marker Score: 18,032 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.72
Marker Score: 624 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.71
Marker Score: 640 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.71
Marker Score: 2,112 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.7
Marker Score: 578 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.69
Marker Score: 822 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.67
Marker Score: 2,425 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.67
Marker Score: 967 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.66
Marker Score: 697 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.62
Marker Score: 4,335 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.6
Marker Score: 1,619 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.59
Marker Score: 1,673 - Cell Name: podocyte (CL0000653)
Fold Change: 1.59
Marker Score: 586 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.57
Marker Score: 1,036 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.57
Marker Score: 2,221 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.56
Marker Score: 752 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.56
Marker Score: 1,670 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.56
Marker Score: 814 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.54
Marker Score: 1,333 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.53
Marker Score: 9,833 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.52
Marker Score: 572 - Cell Name: basal cell (CL0000646)
Fold Change: 1.51
Marker Score: 1,955 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.51
Marker Score: 2,332 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.5
Marker Score: 3,758 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.49
Marker Score: 738 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.48
Marker Score: 4,226 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.48
Marker Score: 7,958 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.44
Marker Score: 6,204 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.43
Marker Score: 580 - Cell Name: ciliated cell (CL0000064)
Fold Change: 1.43
Marker Score: 4,901 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.39
Marker Score: 1,476 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.39
Marker Score: 4,941 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.38
Marker Score: 939 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.38
Marker Score: 2,310 - Cell Name: club cell (CL0000158)
Fold Change: 1.36
Marker Score: 1,592 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.36
Marker Score: 961 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.36
Marker Score: 1,247 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.36
Marker Score: 274 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.35
Marker Score: 4,792
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 76696549
Symbol: PUM2_HUMAN
Name: Pumilio homolog 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12459267
Title: Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.
PubMed ID: 12459267
PubMed ID: 9039502
Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.
PubMed ID: 9039502
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12511597
Title: Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.
PubMed ID: 12511597
PubMed ID: 12771951
Title: Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.
PubMed ID: 12771951
PubMed ID: 12690449
Title: Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells.
PubMed ID: 12690449
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18776931
Title: Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.
PubMed ID: 18776931
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19168546
Title: The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.
PubMed ID: 19168546
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21800163
Title: NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.
PubMed ID: 21800163
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22345517
Title: Pumilio facilitates miRNA regulation of the E2F3 oncogene.
PubMed ID: 22345517
PubMed ID: 22955276
Title: Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs.
PubMed ID: 22955276
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23125361
Title: The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.
PubMed ID: 23125361
DOI: 10.1093/nar/gks1032
PubMed ID: 25349211
Title: SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1).
PubMed ID: 25349211
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25340845
Title: A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.
PubMed ID: 25340845
PubMed ID: 26724866
Title: Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins.
PubMed ID: 26724866
PubMed ID: 28431233
Title: A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.
PubMed ID: 28431233
PubMed ID: 21397187
Title: Alternate modes of cognate RNA recognition by human PUMILIO proteins.
PubMed ID: 21397187
Sequence Information:
- Length: 1066
- Mass: 114216
- Checksum: CF6F9D7998CD5D9E
- Sequence:
MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSVGSSASS SATRRESLST SSDLYKRSSS SLAPIGQPFY NSLGFSSSPS PIGMPLPSQT PGHSLTPPPS LSSHGSSSSL HLGGLTNGSG RYISAAPGAE AKYRSASSTS SLFSSSSQLF PPSRLRYNRS DIMPSGRSRL LEDFRNNRFP NLQLRDLIGH IVEFSQDQHG SRFIQQKLER ATPAERQMVF NEILQAAYQL MTDVFGNYVI QKFFEFGSLD QKLALATRIR GHVLPLALQM YGCRVIQKAL ESISSDQQVI SEMVKELDGH VLKCVKDQNG NHVVQKCIEC VQPQSLQFII DAFKGQVFVL STHPYGCRVI QRILEHCTAE QTLPILEELH QHTEQLVQDQ YGNYVIQHVL EHGRPEDKSK IVSEIRGKVL ALSQHKFASN VVEKCVTHAS RAERALLIDE VCCQNDGPHS ALYTMMKDQY ANYVVQKMID MAEPAQRKII MHKIRPHITT LRKYTYGKHI LAKLEKYYLK NSPDLGPIGG PPNGML
Genular Protein ID: 3449825584
Symbol: B7ZL34_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 985
- Mass: 106003
- Checksum: AD305125806106C9
- Sequence:
MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSGGLTNGS GRYISAAPGA EAKYRSASST SSLFSSSSQL FPPSRLRYNR SDIMPSGRSR LLEDFRNNRF PNLQLRDLIG HIVEFSQDQH GSRFIQQKLE RATPAERQMV FNEILQAAYQ LMTDVFGNYV IQKFFEFGSL DQKLALATRI RGHVLPLALQ MYGCRVIQKA LESISSDQQS EMVKELDGHV LKCVKDQNGN HVVQKCIECV QPQSLQFIID AFKGQVFVLS THPYGCRVIQ RILEHCTAEQ TLPILEELHQ HTEQLVQDQY GNYVIQHVLE HGRPEDKSKI VSEIRGKVLA LSQHKFASNV VEKCVTHASR AERALLIDEV CCQNDGPHSA LYTMMKDQYA NYVVQKMIDM AEPAQRKIIM HKIRPHITTL RKYTYGKHIL AKLEKYYLKN SPDLGPIGGP PNGML
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.