Details for: UFL1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.55
Marker Score: 2,284 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.51
Marker Score: 3,434 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.46
Marker Score: 50,706 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.46
Marker Score: 761 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.42
Marker Score: 3,404 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.42
Marker Score: 423 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.41
Marker Score: 407 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.39
Marker Score: 5,819 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.32
Marker Score: 11,376 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.32
Marker Score: 385 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.31
Marker Score: 1,889 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.31
Marker Score: 762 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.31
Marker Score: 2,871 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.29
Marker Score: 5,077 - Cell Name: plasmablast (CL0000980)
Fold Change: 1.29
Marker Score: 1,714 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.28
Marker Score: 27,297 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.25
Marker Score: 2,644 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.22
Marker Score: 1,266 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.22
Marker Score: 2,157 - Cell Name: basal cell (CL0000646)
Fold Change: 1.21
Marker Score: 1,565 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.18
Marker Score: 10,239 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.14
Marker Score: 3,062 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.14
Marker Score: 12,829 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.12
Marker Score: 9,659 - Cell Name: preosteoblast (CL0007010)
Fold Change: 1.12
Marker Score: 317 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.11
Marker Score: 1,170 - Cell Name: neuron (CL0000540)
Fold Change: 1.11
Marker Score: 4,502 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.1
Marker Score: 4,075 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.1
Marker Score: 271 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.1
Marker Score: 950 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 1.1
Marker Score: 329 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.09
Marker Score: 635 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.08
Marker Score: 3,082 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.07
Marker Score: 10,209 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.07
Marker Score: 7,997 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.07
Marker Score: 435 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.07
Marker Score: 1,657 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.07
Marker Score: 728 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 1.07
Marker Score: 527 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.06
Marker Score: 620 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.06
Marker Score: 494 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.05
Marker Score: 393 - Cell Name: Leydig cell (CL0000178)
Fold Change: 1.05
Marker Score: 1,136 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 1.05
Marker Score: 500 - Cell Name: peptic cell (CL0000155)
Fold Change: 1.05
Marker Score: 438 - Cell Name: blood cell (CL0000081)
Fold Change: 1.05
Marker Score: 12,158 - Cell Name: keratinocyte (CL0000312)
Fold Change: 1.04
Marker Score: 872 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.04
Marker Score: 248 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.04
Marker Score: 693 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.04
Marker Score: 422 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.03
Marker Score: 359 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.03
Marker Score: 566 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.02
Marker Score: 15,265 - Cell Name: osteoblast (CL0000062)
Fold Change: 1.02
Marker Score: 548 - Cell Name: Schwann cell (CL0002573)
Fold Change: 1.02
Marker Score: 354 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.02
Marker Score: 62,673 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.01
Marker Score: 677 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.01
Marker Score: 578 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 1.01
Marker Score: 1,013 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.01
Marker Score: 1,157 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 1
Marker Score: 1,910 - Cell Name: keratocyte (CL0002363)
Fold Change: 1
Marker Score: 231 - Cell Name: hepatocyte (CL0000182)
Fold Change: 1
Marker Score: 685 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1
Marker Score: 918 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1
Marker Score: 484 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,590 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,815 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.99
Marker Score: 3,413 - Cell Name: podocyte (CL0000653)
Fold Change: 0.99
Marker Score: 367 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.99
Marker Score: 2,493 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.98
Marker Score: 17,428 - Cell Name: Unknown (CL0000548)
Fold Change: 0.98
Marker Score: 714 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,368 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.98
Marker Score: 1,053 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.97
Marker Score: 685 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.97
Marker Score: 1,372 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.97
Marker Score: 2,635 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.97
Marker Score: 6,290 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.97
Marker Score: 1,192 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.96
Marker Score: 480 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.96
Marker Score: 440 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.96
Marker Score: 3,699 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.95
Marker Score: 1,728 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.94
Marker Score: 4,070 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.94
Marker Score: 21,065 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.94
Marker Score: 34,600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,380 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.93
Marker Score: 946 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.93
Marker Score: 274 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.93
Marker Score: 35,298 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.93
Marker Score: 8,742 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.93
Marker Score: 2,104 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.93
Marker Score: 645 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 476 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.92
Marker Score: 926 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 434 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.92
Marker Score: 1,726 - Cell Name: enterocyte (CL0000584)
Fold Change: 0.92
Marker Score: 4,399 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 0.92
Marker Score: 817 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.92
Marker Score: 1,011
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3968101754
Symbol: UFL1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9872452
Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9872452
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 20531390
Title: Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
PubMed ID: 20531390
PubMed ID: 20018847
Title: A novel type of E3 ligase for the Ufm1 conjugation system.
PubMed ID: 20018847
PubMed ID: 20164180
Title: A novel LZAP-binding protein, NLBP, inhibits cell invasion.
PubMed ID: 20164180
PubMed ID: 20228063
Title: A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling.
PubMed ID: 20228063
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23152784
Title: Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
PubMed ID: 23152784
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25219498
Title: Modification of ASC1 by UFM1 is crucial for ERalpha transactivation and breast cancer development.
PubMed ID: 25219498
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 30354401
Title: Ufm1-specific ligase Ufl1 regulates endoplasmic reticulum homeostasis and protects against heart failure.
PubMed ID: 30354401
PubMed ID: 30886146
Title: UFL1 promotes histone H4 ufmylation and ATM activation.
PubMed ID: 30886146
PubMed ID: 32160526
Title: A genome-wide ER-phagy screen highlights key roles of mitochondrial metabolism and ER-Resident UFMylation.
PubMed ID: 32160526
PubMed ID: 32050156
Title: UFL1 attenuates IL-1beta-induced inflammatory response in human osteoarthritis chondrocytes.
PubMed ID: 32050156
PubMed ID: 37311461
Title: An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.
PubMed ID: 37311461
Sequence Information:
- Length: 794
- Mass: 89595
- Checksum: C6C1777455551991
- Sequence:
MADAWEEIRR LAADFQRAQF AEATQRLSER NCIEIVNKLI AQKQLEVVHT LDGKEYITPA QISKEMRDEL HVRGGRVNIV DLQQVINVDL IHIENRIGDI IKSEKHVQLV LGQLIDENYL DRLAEEVNDK LQESGQVTIS ELCKTYDLPG NFLTQALTQR LGRIISGHID LDNRGVIFTE AFVARHKARI RGLFSAITRP TAVNSLISKY GFQEQLLYSV LEELVNSGRL RGTVVGGRQD KAVFVPDIYS RTQSTWVDSF FRQNGYLEFD ALSRLGIPDA VSYIKKRYKT TQLLFLKAAC VGQGLVDQVE ASVEEAISSG TWVDIAPLLP TSLSVEDAAI LLQQVMRAFS KQASTVVFSD TVVVSEKFIN DCTELFRELM HQKAEKEMKN NPVHLITEED LKQISTLESV STSKKDKKDE RRRKATEGSG SMRGGGGGNA REYKIKKVKK KGRKDDDSDD ESQSSHTGKK KPEISFMFQD EIEDFLRKHI QDAPEEFISE LAEYLIKPLN KTYLEVVRSV FMSSTTSASG TGRKRTIKDL QEEVSNLYNN IRLFEKGMKF FADDTQAALT KHLLKSVCTD ITNLIFNFLA SDLMMAVDDP AAITSEIRKK ILSKLSEETK VALTKLHNSL NEKSIEDFIS CLDSAAEACD IMVKRGDKKR ERQILFQHRQ ALAEQLKVTE DPALILHLTS VLLFQFSTHS MLHAPGRCVP QIIAFLNSKI PEDQHALLVK YQGLVVKQLV SQSKKTGQGD YPLNNELDKE QEDVASTTRK ELQELSSSIK DLVLKSRKSS VTEE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.