Details for: ICE1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 2.15
Marker Score: 28,608 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.91
Marker Score: 928 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 1.78
Marker Score: 1,746 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.75
Marker Score: 66,319 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.74
Marker Score: 26,020 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.73
Marker Score: 106,520 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.71
Marker Score: 6,605 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.69
Marker Score: 14,527 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.65
Marker Score: 15,722 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.65
Marker Score: 60,882 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.61
Marker Score: 12,313 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.59
Marker Score: 14,917 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.57
Marker Score: 31,206 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.53
Marker Score: 6,330 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.52
Marker Score: 3,335 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.45
Marker Score: 2,238 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.44
Marker Score: 14,826 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.4
Marker Score: 29,773 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.34
Marker Score: 3,830 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.34
Marker Score: 1,539 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.34
Marker Score: 1,192 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.31
Marker Score: 1,199 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.25
Marker Score: 1,514 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.21
Marker Score: 1,633 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.21
Marker Score: 506 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.21
Marker Score: 720 - Cell Name: neuron (CL0000540)
Fold Change: 1.2
Marker Score: 4,887 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.19
Marker Score: 693 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.19
Marker Score: 1,486 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 1.18
Marker Score: 1,174 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.16
Marker Score: 1,284 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.16
Marker Score: 18,179 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.16
Marker Score: 1,447 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.14
Marker Score: 4,772 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.14
Marker Score: 333 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.11
Marker Score: 1,596 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.1
Marker Score: 5,087 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 1.09
Marker Score: 928 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.09
Marker Score: 736 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.08
Marker Score: 1,153 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.05
Marker Score: 2,026 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.05
Marker Score: 553 - Cell Name: Leydig cell (CL0000178)
Fold Change: 1.05
Marker Score: 1,127 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.04
Marker Score: 448 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.04
Marker Score: 689 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.03
Marker Score: 2,183 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.02
Marker Score: 1,105 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.02
Marker Score: 977 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.02
Marker Score: 610 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.01
Marker Score: 590 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.01
Marker Score: 2,699 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.01
Marker Score: 775 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1
Marker Score: 2,394 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.98
Marker Score: 310 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,386 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.98
Marker Score: 311 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.98
Marker Score: 2,307 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 0.98
Marker Score: 654 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.97
Marker Score: 8,529 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.96
Marker Score: 1,201 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.95
Marker Score: 274 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: 0.95
Marker Score: 575 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.94
Marker Score: 3,488 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,390 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.94
Marker Score: 325 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 478 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.92
Marker Score: 5,517 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 433 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.91
Marker Score: 249 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,688 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.9
Marker Score: 930 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.89
Marker Score: 3,507 - Cell Name: podocyte (CL0000653)
Fold Change: 0.89
Marker Score: 329 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.89
Marker Score: 387 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.89
Marker Score: 594 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.88
Marker Score: 458 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,292 - Cell Name: fat cell (CL0000136)
Fold Change: 0.87
Marker Score: 487 - Cell Name: Unknown (CL0000548)
Fold Change: 0.87
Marker Score: 634 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 309 - Cell Name: Unknown (CL0002371)
Fold Change: 0.86
Marker Score: 912 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.86
Marker Score: 8,635 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.85
Marker Score: 321 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.85
Marker Score: 1,939 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4,844 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.84
Marker Score: 1,408 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.83
Marker Score: 1,181 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.83
Marker Score: 873 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.83
Marker Score: 1,227 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.83
Marker Score: 335 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.83
Marker Score: 9,295 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.82
Marker Score: 833 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.82
Marker Score: 2,235 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.81
Marker Score: 857 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.81
Marker Score: 1,322 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.81
Marker Score: 187 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.8
Marker Score: 299 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8
Marker Score: 319 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.8
Marker Score: 438 - Cell Name: classical monocyte (CL0000860)
Fold Change: 0.79
Marker Score: 3,296
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1414521127
Symbol: ICE1_HUMAN
Name: Little elongation complex subunit 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 22195968
Title: The little elongation complex regulates small nuclear RNA transcription.
PubMed ID: 22195968
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23932780
Title: The little elongation complex functions at initiation and elongation phases of snRNA gene transcription.
PubMed ID: 23932780
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 2266
- Mass: 247891
- Checksum: 69EC121F4543B92D
- Sequence:
MMPGETHSAA PGTAADLSRC QGCASLQQNL NEYVEALITL KQKIINTDNL LTEYQKKCDE LQFARRENSN LHHQVEEMLQ KISPLQKCQE ELGSLKAELE EKKSSLKLYQ DTHQEYARVK EECLKSDAQK KKLEAKVKKL QEAAVKQTQD FKQLRNEKKI LEKEFKKTQE RLDEFSKQKN EKELRHIGTQ ISSDSYGSID KRKVKLLLKE LWLCVNTTHR LPGEGSRCVP EKPAKAITSS RVPGEDGTLP PTQGSPLRTS NVQTCLTKLS MEIKEDFLCQ NVEKQSSSGT NCSSDHVFNE NGNLEVLVQS HRDGGSTEFV DHDHFFDEDL QAAIDFFKLP PPLLSPVPSP PPMSSPHPGS LPSSFAPETY FGEYTDSSDN DSVQLRNSAE CVSEDDTTES QNYFGSLRKN KGSGTWEEKP KSHEAIQALN TWEVNKVTTS GLETFTATLR ESSATHSLVG EKHWTTASRS MSDRKRDILH ETKTQMEVRE MDKSVQTEKT IHKLTRGLCI ERLSASPAQE KEAAPGKSEL CSSPLGKRPL NELMESEGKT VLSKMMGSPK SEFTKWTRIN EITSEPDRIT VSGHFHRLSR ELEKEKEDTQ GFTLGESPES EDDDSGDGMD VAGLDIETSF SSSSTLVALS VGSNPQSSSG LDCGNDTDIT TKVFSTEPHH SEHKLQTKTL NTLHLQSEPP ECSIGGNNLE NSLCALSPEL GASNFNDQKS SGIEYTKVVK GLTKIHSLPR SVFMKATKDG QCESQDPRIE LTLNKPDFTS LIGSQAALIK SGLGFVKSTS WHHSDLLRKG GEESLRAKSE HEQKTSHQLQ KAMPFLQNRG PTPKPDLLRE NNNPVEFKTT ASVLPNQVSV ITKQTRPEKV QSAKLEHLRP HRVEPTLVTE NSGNKTGMST VAKCDGERDD TTQNITEVAA VKSISPEVSA SRRKLDFNSP GGSSPVENSD CSTNSRLSFS PENILIQNQD IVREAAVQGD GQKQRQPQAT DLDSSGTHGS EMLPATEVTV SGGFSVEETS CGDTGRSGGE ALAVANDSTS TPQNANGLWK LKSTTPGGAL PECFGTTDTT FSSAFCRKHG ETQDTSQSSL PGTLHCYTGI REGGDDTEVE SEAFSCSEGS EQQDAPDDSQ KNLGDTDAAV AEVRPSLEVG YLTSALQDFN ISTFSELDRL STSEVVMFLE SCQLGDYSSG DSVSECSSKG TLSKEMNKEL KASEIGEKYR KQPCEEETLG TCEEWIESEE DDYSLKNTSQ LTQCSLETLS EVLTKIRQEL QTNSEDCNGK DTGSLLLLNV NNNMTTENLK EKSPFRETTG SSSHASEPTP QAAALDTEGS SPISGMPQNE NPQSRPEARS DAGRQTDGGE EDLPEPVEPS ALCSDSVMEP SIEQSSNCEA ETTFQCQIAT VTSEVINVLI NKDQNLVIEK GDNWTIISGV AVLPHVDQVT LCDIPGDIPI SQDQGELEAG CIPVTSAEKS PEASHTGPAF QEAPCGNNLS CPQEDVSSSG QSTNFDKSRL RNRPVKPSIW ISSQIYDQNF ETQIVASDHT YYNSKLEPSG KNKNRSKISN KDQSNKPVKT SASSRVETHQ SEVAQSFSGE KANTKTQRSQ TQTILANADT STPTDCSPDT LSKIRQEVGP PLPPLLAPLI ATPPRTSQPL SPLISSSSPS SPASPVGQVS PFRETPVPPA MSPWPEDPRR ASPPDPSPSP SAASASERVV PSPLQFCAAT PKHALPVPGR LPPCASGHAA VGGPQENSVK ILDTMYPELS ARARTLNILK GNIQLTRGPP ADCKNLPGPA SAMIGFKTIT SAATAFVKTG SSSGGDCNQD KSRDLGTQQD SSGKRTLSTS TLRSAKRLRL DTGSPEPETR GVTAEGIHKN LPGNLPPAEV ATTNEERSCS SPAVSAVSQL PLSPKETVES HDKAIANALK KIAEFSFDLL PVIRSHVYVG NISKKPVMRD QEKEVVYEFS TTKKHLAECL LHSILSELKI QKISMDHNYI HALCRVYVGI CRQLGDLERA RLFCYSLLKE DFPESEKLTL FIANMWHDIF LSQSVINKAM QLVARQRAKG EVLNCLRAFL NWEKNAPVDV GFMVSKLLLT IQLCPKTEFQ PSEKFGEDLS DNTWEYIFAI DLLCCHQKWI WTHDNIISKE LWPVMDKWIK YRKGHANIAY TPDIIIASIL RLIGRLGQLG LKEGFPSAVK NISSVIGMFI QHAHDEDIPW GIQLAAVYAL CDLSPSNPAE ISKILEAWRR EASKSVPSAI VSCLEEVSAL STEELG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.