Details for: SMG5

Gene ID: 23381

Symbol: SMG5

Ensembl ID: ENSG00000198952

Description: SMG5 nonsense mediated mRNA decay factor

Associated with

Other Information

Genular Protein ID: 462443411

Symbol: SMG5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14636577

Title: Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

PubMed ID: 14636577

DOI: 10.1016/s1097-2765(03)00443-x

PubMed ID: 12699629

Title: Functional conservation of the telomerase protein Est1p in humans.

PubMed ID: 12699629

DOI: 10.1016/s0960-9822(03)00210-0

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15546618

Title: SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.

PubMed ID: 15546618

DOI: 10.1016/j.molcel.2004.10.013

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 17053788

Title: Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.

PubMed ID: 17053788

DOI: 10.1038/sj.emboj.7601377

Sequence Information:

  • Length: 1016
  • Mass: 113928
  • Checksum: B6F8F9B53CF42195
  • Sequence:
  • MSQGPPTGES SEPEAKVLHT KRLYRAVVEA VHRLDLILCN KTAYQEVFKP ENISLRNKLR 
    ELCVKLMFLH PVDYGRKAEE LLWRKVYYEV IQLIKTNKKH IHSRSTLECA YRTHLVAGIG 
    FYQHLLLYIQ SHYQLELQCC IDWTHVTDPL IGCKKPVSAS GKEMDWAQMA CHRCLVYLGD 
    LSRYQNELAG VDTELLAERF YYQALSVAPQ IGMPFNQLGT LAGSKYYNVE AMYCYLRCIQ 
    SEVSFEGAYG NLKRLYDKAA KMYHQLKKCE TRKLSPGKKR CKDIKRLLVN FMYLQSLLQP 
    KSSSVDSELT SLCQSVLEDF NLCLFYLPSS PNLSLASEDE EEYESGYAFL PDLLIFQMVI 
    ICLMCVHSLE RAGSKQYSAA IAFTLALFSH LVNHVNIRLQ AELEEGENPV PAFQSDGTDE 
    PESKEPVEKE EEPDPEPPPV TPQVGEGRKS RKFSRLSCLR RRRHPPKVGD DSDLSEGFES 
    DSSHDSARAS EGSDSGSDKS LEGGGTAFDA ETDSEMNSQE SRSDLEDMEE EEGTRSPTLE 
    PPRGRSEAPD SLNGPLGPSE ASIASNLQAM STQMFQTKRC FRLAPTFSNL LLQPTTNPHT 
    SASHRPCVNG DVDKPSEPAS EEGSESEGSE SSGRSCRNER SIQEKLQVLM AEGLLPAVKV 
    FLDWLRTNPD LIIVCAQSSQ SLWNRLSVLL NLLPAAGELQ ESGLALCPEV QDLLEGCELP 
    DLPSSLLLPE DMALRNLPPL RAAHRRFNFD TDRPLLSTLE ESVVRICCIR SFGHFIARLQ 
    GSILQFNPEV GIFVSIAQSE QESLLQQAQA QFRMAQEEAR RNRLMRDMAQ LRLQLEVSQL 
    EGSLQQPKAQ SAMSPYLVPD TQALCHHLPV IRQLATSGRF IVIIPRTVID GLDLLKKEHP 
    GARDGIRYLE AEFKKGNRYI RCQKEVGKSF ERHKLKRQDA DAWTLYKILD SCKQLTLAQG 
    AGEEDPSGMV TIITGLPLDN PSVLSGPMQA ALQAAAHASV DIKNVLDFYK QWKEIG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.