Details for: SMG5
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: germ cell (CL0000586)
Fold Change: 1.59
Marker Score: 2,784 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,210 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.17
Marker Score: 71,715 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.14
Marker Score: 11,791 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.11
Marker Score: 1,706 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.1
Marker Score: 9,472 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.1
Marker Score: 733 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.09
Marker Score: 10,352 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.08
Marker Score: 453 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.07
Marker Score: 3,804 - Cell Name: neuron (CL0000540)
Fold Change: 1.03
Marker Score: 4,210 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,725 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,949 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,396 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.96
Marker Score: 35,385 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.94
Marker Score: 8,868 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.94
Marker Score: 256 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.94
Marker Score: 14,650 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 479 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.93
Marker Score: 853 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 435 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.92
Marker Score: 20,465 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,707 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.89
Marker Score: 1,443 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.87
Marker Score: 986 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.86
Marker Score: 955 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.86
Marker Score: 18,403 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 309 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4,878 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.83
Marker Score: 3,220 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.83
Marker Score: 715 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.8
Marker Score: 30,525 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.8
Marker Score: 15,914 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 590 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.76
Marker Score: 2,628 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 304 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.74
Marker Score: 799 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.74
Marker Score: 297 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.72
Marker Score: 1,042 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.72
Marker Score: 3,005 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.72
Marker Score: 252 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 374 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.72
Marker Score: 5,517 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.71
Marker Score: 347 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.71
Marker Score: 769 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.71
Marker Score: 10,660 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.71
Marker Score: 368 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.7
Marker Score: 408 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.7
Marker Score: 1,638 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.69
Marker Score: 2,911 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.68
Marker Score: 12,117 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 614 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.67
Marker Score: 388 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.67
Marker Score: 3,077 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.64
Marker Score: 1,352 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.64
Marker Score: 434 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.63
Marker Score: 766 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.63
Marker Score: 1,585 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.63
Marker Score: 728 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.63
Marker Score: 1,383 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 0.63
Marker Score: 1,969 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.62
Marker Score: 201 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.62
Marker Score: 1,492 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.62
Marker Score: 653 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.62
Marker Score: 536 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.61
Marker Score: 250 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.61
Marker Score: 820 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.61
Marker Score: 155 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.61
Marker Score: 177 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.61
Marker Score: 206 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.6
Marker Score: 2,970 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.6
Marker Score: 399 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.6
Marker Score: 610 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.59
Marker Score: 405 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.59
Marker Score: 408 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.59
Marker Score: 9,427 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.58
Marker Score: 363 - Cell Name: oocyte (CL0000023)
Fold Change: 0.58
Marker Score: 143 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.58
Marker Score: 814 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.57
Marker Score: 720 - Cell Name: Unknown (CL0002371)
Fold Change: 0.57
Marker Score: 610 - Cell Name: podocyte (CL0000653)
Fold Change: 0.57
Marker Score: 211 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.57
Marker Score: 213 - Cell Name: fat cell (CL0000136)
Fold Change: 0.57
Marker Score: 317 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.57
Marker Score: 2,368 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.57
Marker Score: 3,606 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.56
Marker Score: 297 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.56
Marker Score: 5,667 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.56
Marker Score: 162 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.56
Marker Score: 336 - Cell Name: Unknown (CL0000548)
Fold Change: 0.56
Marker Score: 409 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.56
Marker Score: 395 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.56
Marker Score: 234 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.56
Marker Score: 308 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.56
Marker Score: 2,409 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.55
Marker Score: 416 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.55
Marker Score: 4,116
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 462443411
Symbol: SMG5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14636577
Title: Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.
PubMed ID: 14636577
PubMed ID: 12699629
Title: Functional conservation of the telomerase protein Est1p in humans.
PubMed ID: 12699629
PubMed ID: 10470851
Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10470851
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15546618
Title: SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
PubMed ID: 15546618
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 17053788
Title: Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
PubMed ID: 17053788
Sequence Information:
- Length: 1016
- Mass: 113928
- Checksum: B6F8F9B53CF42195
- Sequence:
MSQGPPTGES SEPEAKVLHT KRLYRAVVEA VHRLDLILCN KTAYQEVFKP ENISLRNKLR ELCVKLMFLH PVDYGRKAEE LLWRKVYYEV IQLIKTNKKH IHSRSTLECA YRTHLVAGIG FYQHLLLYIQ SHYQLELQCC IDWTHVTDPL IGCKKPVSAS GKEMDWAQMA CHRCLVYLGD LSRYQNELAG VDTELLAERF YYQALSVAPQ IGMPFNQLGT LAGSKYYNVE AMYCYLRCIQ SEVSFEGAYG NLKRLYDKAA KMYHQLKKCE TRKLSPGKKR CKDIKRLLVN FMYLQSLLQP KSSSVDSELT SLCQSVLEDF NLCLFYLPSS PNLSLASEDE EEYESGYAFL PDLLIFQMVI ICLMCVHSLE RAGSKQYSAA IAFTLALFSH LVNHVNIRLQ AELEEGENPV PAFQSDGTDE PESKEPVEKE EEPDPEPPPV TPQVGEGRKS RKFSRLSCLR RRRHPPKVGD DSDLSEGFES DSSHDSARAS EGSDSGSDKS LEGGGTAFDA ETDSEMNSQE SRSDLEDMEE EEGTRSPTLE PPRGRSEAPD SLNGPLGPSE ASIASNLQAM STQMFQTKRC FRLAPTFSNL LLQPTTNPHT SASHRPCVNG DVDKPSEPAS EEGSESEGSE SSGRSCRNER SIQEKLQVLM AEGLLPAVKV FLDWLRTNPD LIIVCAQSSQ SLWNRLSVLL NLLPAAGELQ ESGLALCPEV QDLLEGCELP DLPSSLLLPE DMALRNLPPL RAAHRRFNFD TDRPLLSTLE ESVVRICCIR SFGHFIARLQ GSILQFNPEV GIFVSIAQSE QESLLQQAQA QFRMAQEEAR RNRLMRDMAQ LRLQLEVSQL EGSLQQPKAQ SAMSPYLVPD TQALCHHLPV IRQLATSGRF IVIIPRTVID GLDLLKKEHP GARDGIRYLE AEFKKGNRYI RCQKEVGKSF ERHKLKRQDA DAWTLYKILD SCKQLTLAQG AGEEDPSGMV TIITGLPLDN PSVLSGPMQA ALQAAAHASV DIKNVLDFYK QWKEIG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.