Details for: MAU2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: neuron (CL0000540)
Fold Change: 1.55
Marker Score: 6,316 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.46
Marker Score: 55,289 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.45
Marker Score: 21,631 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.45
Marker Score: 13,598 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.44
Marker Score: 5,579 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.41
Marker Score: 10,806 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.39
Marker Score: 85,657 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.39
Marker Score: 51,209 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.39
Marker Score: 29,582 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.36
Marker Score: 12,942 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.34
Marker Score: 26,673 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.31
Marker Score: 11,256 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.29
Marker Score: 1,993 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.27
Marker Score: 28,335 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.25
Marker Score: 2,736 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.23
Marker Score: 718 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.21
Marker Score: 5,065 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.21
Marker Score: 5,015 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.18
Marker Score: 12,166 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.17
Marker Score: 1,571 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.14
Marker Score: 4,040 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.12
Marker Score: 1,294 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.12
Marker Score: 1,236 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.11
Marker Score: 955 - Cell Name: interneuron (CL0000099)
Fold Change: 1.1
Marker Score: 504 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.07
Marker Score: 1,217 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.07
Marker Score: 447 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.04
Marker Score: 16,305 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.04
Marker Score: 329 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.03
Marker Score: 600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1
Marker Score: 1,216 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,705 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,930 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.99
Marker Score: 1,067 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,393 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.97
Marker Score: 1,872 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.96
Marker Score: 1,192 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,397 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 479 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 434 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.91
Marker Score: 618 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.9
Marker Score: 1,091 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,705 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.9
Marker Score: 2,147 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.89
Marker Score: 1,452 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.89
Marker Score: 282 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.88
Marker Score: 435 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.88
Marker Score: 869 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.86
Marker Score: 251 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.86
Marker Score: 15,188 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4,858 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.85
Marker Score: 1,729 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.85
Marker Score: 28,687 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.85
Marker Score: 295 - Cell Name: fat cell (CL0000136)
Fold Change: 0.83
Marker Score: 464 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.81
Marker Score: 222 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.81
Marker Score: 392 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.8
Marker Score: 422 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.79
Marker Score: 3,670 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.79
Marker Score: 593 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.79
Marker Score: 315 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.78
Marker Score: 3,260 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.78
Marker Score: 468 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 593 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.78
Marker Score: 401 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.77
Marker Score: 735 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.77
Marker Score: 590 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.76
Marker Score: 659 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.76
Marker Score: 1,787 - Cell Name: podocyte (CL0000653)
Fold Change: 0.74
Marker Score: 275 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.73
Marker Score: 1,032 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.73
Marker Score: 3,055 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.73
Marker Score: 408 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 372 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.72
Marker Score: 590 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.72
Marker Score: 1,030 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.71
Marker Score: 653 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.71
Marker Score: 763 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.7
Marker Score: 201 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.7
Marker Score: 724 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.7
Marker Score: 706 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.69
Marker Score: 218 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.67
Marker Score: 273 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.67
Marker Score: 402 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.67
Marker Score: 4,029 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.67
Marker Score: 1,678 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 610 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.67
Marker Score: 257 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.67
Marker Score: 446 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 0.66
Marker Score: 935 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.66
Marker Score: 247 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.66
Marker Score: 464 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.65
Marker Score: 323 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.65
Marker Score: 1,367 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.65
Marker Score: 428 - Cell Name: basal cell (CL0000646)
Fold Change: 0.65
Marker Score: 833 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.64
Marker Score: 682
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3552904301
Symbol: SCC4_HUMAN
Name: MAU2 chromatid cohesion factor homolog
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16802858
Title: Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance.
PubMed ID: 16802858
PubMed ID: 16682347
Title: Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.
PubMed ID: 16682347
PubMed ID: 21934712
Title: Isolated NIBPL missense mutations that cause Cornelia de Lange syndrome alter MAU2 interaction.
PubMed ID: 21934712
PubMed ID: 22628566
Title: In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
PubMed ID: 22628566
PubMed ID: 28167679
Title: Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.
PubMed ID: 28167679
DOI: 10.1242/jcs.197236
Sequence Information:
- Length: 613
- Mass: 69082
- Checksum: 47E33F5CE6504047
- Sequence:
MAAQAAAAAQ AAAAQAAQAE AADSWYLALL GFAEHFRTSS PPKIRLCVHC LQAVFPFKPP QRIEARTHLQ LGSVLYHHTK NSEQARSHLE KAWLISQQIP QFEDVKFEAA SLLSELYCQE NSVDAAKPLL RKAIQISQQT PYWHCRLLFQ LAQLHTLEKD LVSACDLLGV GAEYARVVGS EYTRALFLLS KGMLLLMERK LQEVHPLLTL CGQIVENWQG NPIQKESLRV FFLVLQVTHY LDAGQVKSVK PCLKQLQQCI QTISTLHDDE ILPSNPADLF HWLPKEHMCV LVYLVTVMHS MQAGYLEKAQ KYTDKALMQL EKLKMLDCSP ILSSFQVILL EHIIMCRLVT GHKATALQEI SQVCQLCQQS PRLFSNHAAQ LHTLLGLYCV SVNCMDNAEA QFTTALRLTN HQELWAFIVT NLASVYIREG NRHQEVLYSL LERINPDHSF PVSSHCLRAA AFYVRGLFSF FQGRYNEAKR FLRETLKMSN AEDLNRLTAC SLVLLGHIFY VLGNHRESNN MVVPAMQLAS KIPDMSVQLW SSALLRDLNK ACGNAMDAHE AAQMHQNFSQ QLLQDHIEAC SLPEHNLITW TDGPPPVQFQ AQNGPNTSLA SLL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.